公开(公告)号：US20150297467A1

公开(公告)日：2015-10-22

申请号：US14255223

申请日：2014-04-17

Applicant: DENTSPLY International Inc.

Inventor： Joachim E. KLEE ,  Stefan BRUGGER ,  Helmut RITTER ,  Christoph WEBER ,  Oliver ELSNER ,  Mareike BARDTS ,  Andreas FACHER ,  Sven POHLE

IPC: A61K6/083 ,  C08L33/02

CPC classification number: A61K6/0835 ,  C08L33/02 ,  C08L2201/54 ,  C09D133/02

Abstract: An aqueous dental glass ionomer composition comprising (a) a reactive particulate glass, and (b) a linear or branched polymer comprising acidic groups, which is reactive with the particulate glass in a cement reaction, whereby the linear or branched polymer comprising acidic groups has a polymer backbone and optionally pendant side chains, (c) optionally dispersed nanoparticles, and (d) optionally a low molecular compound, characterized in that the glass ionomer composition comprises—S.sub.xH groups, wherein x is an integer of from 1 to 6, which crosslink the particulate glass and/or the linear polycarboxylic acid and/or the optional dispersed nanoparticles and/or the optional low molecular compound.

Abstract translation: 一种水性牙科玻璃离聚物组合物，其包含（a）反应性颗粒玻璃，和（b）包含酸性基团的直链或支链聚合物，其在水泥反应中与颗粒状玻璃反应，由此包含酸性基团的直链或支链聚合物具有 聚合物主链和任选的侧链侧链，（c）任选分散的纳米颗粒，和（d）任选的低分子化合物，其特征在于所述玻璃离聚物组合物包含-SH x H基团，其中x为1的整数 至6，其使颗粒状玻璃和/或线性多元羧酸和/或任选的分散的纳米颗粒和/或任选的低分子化合物交联。

公开(公告)号：US20140058010A1

公开(公告)日：2014-02-27

申请号：US14065682

申请日：2013-10-29

Applicant: DENTSPLY International Inc.

Inventor： Joachim E. KLEE ,  Andreas FACHER ,  Christoph WEBER ,  Rolf MULHAUPT ,  Martin SCHMIDER

IPC: A61K6/00

CPC classification number: A61K6/0017 ,  C08L33/00 ,  C08L63/00

Abstract: One-component heat-curable sealant composition for the protection of exposed dental surfaces, comprising (a) a polymerisable monomer and/or oligomer which has at least two polymerizable double bonds per molecule, and (b) an initiator system comprising benzoylperoxide in an amount of at least 2 wt.-% based on the total composition.

Abstract translation: 用于保护暴露的牙齿表面的单组分可热固化的密封剂组合物，其包含（a）每分子具有至少两个可聚合双键的可聚合单体和/或低聚物，和（b）包含量为过氧化苯甲酰的引发剂体系 至少为2重量％。

公开(公告)号：US20160024334A1

公开(公告)日：2016-01-28

申请号：US14872557

申请日：2015-10-01

Applicant: DENTSPLY International Inc.

Inventor： Simon STELZIG ,  Jörg KEMPTER ,  Stephanie NOERPEL ,  Joachim E. KLEE ,  Andreas ,  Uwe WALZ ,  Christoph WEBER

IPC: C09D143/04 ,  B01J2/16 ,  C08K3/40

CPC classification number: C09D143/04 ,  A61K6/0008 ,  A61K6/0076 ,  A61K6/0085 ,  A61K6/0091 ,  A61K6/0215 ,  A61K6/024 ,  A61K6/025 ,  A61K6/083 ,  B01J2/16 ,  B05D7/24 ,  C01P2004/61 ,  C03C14/008 ,  C03C17/00 ,  C03C17/30 ,  C03C2214/12 ,  C08K3/40 ,  C08K5/5419 ,  C09C1/40 ,  C09C3/00 ,  C09C3/006 ,  C09C3/045 ,  C09C3/08 ,  C09C3/12 ,  C08L33/00

Abstract: A process for the preparation of composite filler particles, comprising: (a) coating a particulate filler having a median particle size (D50) of from 1 to 1200 nm; (b) agglomerating the coated particulate filler, for providing a granulation of the coated particulate filler wherein the granulation contains the coated particulate filler particles whereby the at least one coating layer may be crosslinked by crosslinking groups obtained by reacting the reactive groups and optionally a further crosslinking agent.

公开(公告)号：US20150335535A1

公开(公告)日：2015-11-26

申请号：US14580893

申请日：2014-12-23

Applicant: DENTSPLY INTERNATIONAL INC.

Inventor： Joachim E. KLEE ,  Uwe LEHMANN

IPC: A61K6/00

CPC classification number: A61K6/0029 ,  A61K6/0023 ,  C08L33/26 ,  C08L43/02

Abstract: A one-part self-etching, self-priming dental adhesive having a pH of at most 2, which comprises an aqueous mixture containing (i) one or more polymerizable monomers optionally containing an acidic group, (ii) optionally one or more organic or inorganic acids, (iii) a polymerization initiator, and (iv) a thermal polymerisation inhibitor of the following formula (I): wherein R′1 represents a hydrogen atom, or a saturated hydrocarbon group having 1 to 18 carbon atoms. R′2, which may be the same or different if more than one R′2 is present, independently represent a saturated hydrocarbon group having 1 to 18 carbon atoms, and c represents an integer of from 1 to 4.

Abstract translation: 一种具有pH至多为2的一部分自蚀刻自吸牙科粘合剂，其包含含有（i）一种或多种任选含有酸性基团的可聚合单体的水性混合物，（ii）任选的一种或多种有机或 无机酸，（iii）聚合引发剂，和（iv）下式（I）的热聚合抑制剂：其中R'1表示氢原子或具有1至18个碳原子的饱和烃基。 R'2可以相同或不同，如果多于一个R'2存在，独立地表示具有1至18个碳原子的饱和烃基，c表示1至4的整数。

公开(公告)号：US20150105489A1

公开(公告)日：2015-04-16

申请号：US14574716

申请日：2014-12-18

Applicant: DENTSPLY International Inc.

Inventor： Joachim E. KLEE ,  Uwe WALZ ,  Christoph WEBER

IPC: A61K6/083

CPC classification number: A61K6/0835 ,  A61K6/0038 ,  A61K6/083 ,  A61K6/087 ,  C08L33/26 ,  C08L79/02

Abstract: The invention concerns a dental composition comprising bisacrylamides that are polymerizable by free-radical polymerization and by Michael-addition polymerization with amities. The application of polymerization and addition polymerization with amines opens the possibility to completely reacted materials that have no oxygen inhibited layers. The claimed bisacrylamides have an improved hydrolytic stability.

Abstract translation: 本发明涉及一种包含双丙烯酰胺的牙科用组合物，其可通过自由基聚合和通过与amities的迈克尔加成聚合而聚合。 聚合和加成聚合与胺的应用开启了不具有抑氧层的完全反应的材料的可能性。 要求保护的双丙烯酰胺具有改进的水解稳定性。

公开(公告)号：US20150099821A1

公开(公告)日：2015-04-09

申请号：US14505687

申请日：2014-10-03

Applicant: DENTSPLY INTERNATIONAL INC.

Inventor： Hui LU ,  Xiaoming JIN ,  Joachim E. KLEE ,  Bernard KOLTISKO

IPC: A61K6/083

CPC classification number: A61K6/083 ,  A61K6/0008 ,  C07D295/24 ,  C08L33/10

Abstract: A dental composite composition is disclosed that includes a polymerizable resin, filler particles, and at least one polymerizable stable radical. A variety of polymerizable stable radicals may be employed, including those that have a 2,2,6,6-tetramethylpiperidinyl-1-oxyl moiety. Compositions as described herein exhibit excellent mechanical strength, hardness, and flexural modulus, while also significantly decreasing shrinkage stress caused by polymerization.

Abstract translation: 公开了一种包含可聚合树脂，填料颗粒和至少一个可聚合的稳定基团的牙科复合组合物。 可以使用各种可聚合的稳定基团，包括具有2,2,6,6-四甲基哌啶基-1-氧基部分的那些。 如本文所述的组合物表现出优异的机械强度，硬度和弯曲模量，同时也显着降低由聚合引起的收缩应力。