-
公开(公告)号:US20240280547A1
公开(公告)日:2024-08-22
申请号:US18653099
申请日:2024-05-02
Applicant: Dionex Softron GmbH
Inventor: Christoph HOLLNAGEL , Hermann HOCHGRAEBER , Thomas WACHINGER
CPC classification number: G01N30/20 , G01N30/14 , G01N2030/201 , G01N2030/207 , G01N30/22 , G01N30/36
Abstract: A method of introducing a sample into a separation column includes introducing the sample into a trap column, isolating the trap column from ambient atmosphere and pressurizing the trap column to a first pressure while the trap column is isolated from ambient atmosphere, providing a fluid connection between the trap column and the separation column after pressurizing the trap column to the first pressure, supplying the sample from the trap column to the separation column.
-
公开(公告)号:US20210102922A1
公开(公告)日:2021-04-08
申请号:US17072997
申请日:2020-10-16
Applicant: Dionex Softron GmbH
Inventor: Christoph HOLLNAGEL , Hermann HOCHGRAEBER , Thomas WACHINGER
Abstract: A method of introducing a sample into a separation column includes introducing the sample into a trap column, isolating the trap column from ambient atmosphere and pressurizing the trap column to a first pressure while the trap column is isolated from ambient atmosphere, providing a fluid connection between the trap column and the separation column after pressurizing the trap column to the first pressure, supplying the sample from the trap column to the separation column.
-
公开(公告)号:US20180128792A1
公开(公告)日:2018-05-10
申请号:US15809239
申请日:2017-11-10
Applicant: DIONEX SOFTRON GMBH
Inventor: Thomas WACHINGER , Christoph HOLLNAGEL
CPC classification number: G01N30/6034 , G01N30/14 , G01N30/20 , G01N30/24 , G01N2030/027 , G01N2030/201 , G01N2030/202 , G01N2030/385
Abstract: A liquid chromatography system includes a separation column, a trap column, and a first switching valve. The first switching valve is adapted to assume a first switching position for bringing a sample into the trap column in a first flow direction. The switching valve is also adapted to assume a second switching position for fluidly connecting the trap column with the separation column and providing a flow from the trap column to the separation column in a second flow direction. The second flow direction is opposite to the first flow direction. The first switching valve is adapted to assume a third switching position for fluidly connecting the trap column, with the separation column and providing a flow from the trap column to the separation column in the first flow direction.
-
公开(公告)号:US20210199628A1
公开(公告)日:2021-07-01
申请号:US17199812
申请日:2021-03-12
Applicant: DIONEX SOFTRON GMBH
Inventor: Christoph HOLLNAGEL , Remco SWART , Hermann HOCHGRAEBER
Abstract: A method performed in a liquid chromatography system includes a metering device pushing a sample into a trap column. The metering device sucks in the sample from a sample reservoir, wherein the sucking in the sample from a sample reservoir precedes the step of pushing the sample into the trap column. The liquid chromatography system also includes a trap column and a metering device, wherein the system is adapted to assume a configuration allowing the metering device to push a sample into the trap column and wherein the metering device is adapted to push the sample into the trap column in this configuration, wherein the system is adapted to assume a configuration allowing the sample to be sucked into the system by means of the metering device. Furthermore, the invention relates to a use of the liquid chromatography system for liquid chromatography, in particular of high-pressure liquid chromatography.
-
公开(公告)号:US20230070054A1
公开(公告)日:2023-03-09
申请号:US17929940
申请日:2022-09-06
Applicant: Dionex Softron GmbH
Inventor: Michael KOLBE , Christoph HOLLNAGEL , Hermann HOCHGRAEBER , Robert SPRINGER
Abstract: The present invention relates to a needle (1), wherein the needle (1) comprises a channel (12) extending through the needle (1), wherein the needle (1) comprises a needle tip (11), wherein the channel (12) comprises an opening at the needle tip (11), wherein the needle (1) defines an axial direction (x), wherein the axial direction (x) defines a distal direction and a proximal direction, wherein the needle tip (11) is a distal portion of the needle (1), and wherein the needle tip (11) comprises a first surface section (112) and a second surface section (111), wherein the first surface section (112) is arranged at a first angle (α) with respect to the axial direction (x) and the second surface section (111) is arranged at a second angle (β) with respect to the axial direction (x), wherein the first angle is different from the second angle. The present invention also relates to a corresponding apparatus, system and use.
-
公开(公告)号:US20180128789A1
公开(公告)日:2018-05-10
申请号:US15809136
申请日:2017-11-10
Applicant: DIONEX SOFTRON GMBH
Inventor: Christoph HOLLNAGEL , Remco SWART , Hermann HOCHGRAEBER
CPC classification number: G01N30/32 , G01N30/20 , G01N30/22 , G01N30/24 , G01N2030/027
Abstract: A method performed in a liquid chromatography system that includes a metering device pushing a sample into a trap column. The metering device sucks in the sample from a sample reservoir, wherein the sucking in the sample from a sample reservoir precedes the step of pushing the sample into the trap column. The liquid chromatography system also includes a trap column and a metering device (100), wherein the system (1000) is adapted to assume a configuration allowing the metering device (100) to push a sample into the trap column (6) and wherein the metering device (100) is adapted to push the sample into the trap column (6) in this configuration, wherein the system (1000) is adapted to assume a configuration allowing the sample to be sucked into the system (1000) by means of the metering device (100). Furthermore, the invention relates to a use of the liquid chromatography system (1000) for liquid chromatography, in particular of high pressure liquid chromatography.
-
公开(公告)号:US20180128788A1
公开(公告)日:2018-05-10
申请号:US15809270
申请日:2017-11-10
Applicant: DIONEX SOFTRON GMBH
Inventor: Thomas WACHINGER , Christoph HOLLNAGEL
CPC classification number: G01N30/20 , B01D15/22 , G01N30/24 , G01N30/468 , G01N30/60 , G01N2030/027 , G01N2030/085 , G01N2030/207
Abstract: A system for component interconnection for use in liquid chromatography includes a first switching valve and a second switching valve. A first connecting line fluidly connects the first switching valve to the second switching valve. A second connecting line fluidly connects the first switching valve to the second switching valve. A metering device is located in the first connecting line.
-
公开(公告)号:US20180128787A1
公开(公告)日:2018-05-10
申请号:US15809190
申请日:2017-11-10
Applicant: DIONEX SOFTRON GMBH
Inventor: Christoph HOLLNAGEL , Hermann Hochgraeber , Thomas Wachinger
CPC classification number: G01N30/20 , G01N30/14 , G01N30/36 , G01N2030/207
Abstract: A method of introducing a sample into a separation column includes introducing the sample into a trap column, isolating the trap column from ambient atmosphere and pressurizing the trap column to a first pressure while the trap column is isolated from ambient atmosphere, providing a fluid connection between the trap column and the separation column after pressurizing the trap column to the first pressure, supplying the sample from the trap column to the separation column.
-
-
-
-
-
-
-