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公开(公告)号：US11591367B2
公开(公告)日：2023-02-28
申请号：US16338758
申请日：2017-10-02
申请人： DSM IP ASSETS B.V.
发明人： Marc Heidl , Eileen Jackson
IPC分类号： C07K7/06 , A61K8/64 , A61Q19/10 , A61K8/23 , A61K8/25 , A61K8/27 , A61K8/29 , A61K8/34 , A61Q19/04
摘要： The present invention relates to novel selective melanocortin-1 receptor (MC1R) agonists as well as the use thereof as skin tanning agents.
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公开(公告)号：US11168054B2
公开(公告)日：2021-11-09
申请号：US16061418
申请日：2016-12-14
申请人： DSM IP ASSETS B.V.
发明人： Igor Bendik , Piero Geotti-Bianchini , Marc Heidl , Eileen Jackson , Alexander Schlifke-Poschalko
IPC分类号： C07C401/00 , A61K8/34 , A61Q19/08
摘要： Novel biaromatic compounds, which are vitamin D analogs, processes for their preparation and cosmetic, dermatological and pharmaceutical preparations containing one or more of these compounds.
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公开(公告)号：US10849838B2
公开(公告)日：2020-12-01
申请号：US16062279
申请日：2016-12-14
申请人： DSM IP ASSETS B.V.
发明人： Igor Bendik , Piero Geotti-Bianchini , Marc Heidl , Eileen Jackson , Alexander Schlifke-Poschalko
摘要： Novel biaromatic compounds, which are vitamin D analogs, processes for their preparation and cosmetic, dermatological and pharmaceutical preparations containing one or more of these compounds.
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公开(公告)号：US10550097B2
公开(公告)日：2020-02-04
申请号：US15745754
申请日：2016-07-07
申请人： DSM IP ASSETS B.V.
发明人： Stéphanie Boudon , Piero Geotti-Bianchini , Marc Heidl , Eileen Jackson , Alexander Schlifke-Poschalko
IPC分类号： C07D401/10 , A61K8/49 , A61Q19/08 , C07D223/04 , C07D265/30 , C07D211/16
摘要： The present invention relates to novel selective 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors and the use thereof to prevent age-induced skin structure and function defects.
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公开(公告)号：US11753440B2
公开(公告)日：2023-09-12
申请号：US15734751
申请日：2019-06-05
申请人： DSM IP Assets B.V.
发明人： Marc Heidl , Piero Geotti-Bianchini
CPC分类号： C07K5/1019 , C07K1/064 , C07K5/06156 , C07K5/0817 , C07K5/1016 , C07K5/1027
摘要： Methods for the synthesis of arginine-containing peptides are provided. The methods include a deprotection step that minimizes the transfer of by-products deriving from cleaved sulfonyl-5 based side chain protecting groups from arginine to amino acids carrying electron rich side chains.
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公开(公告)号：US10570075B2
公开(公告)日：2020-02-25
申请号：US16062463
申请日：2016-12-14
申请人： DSM IP ASSETS B.V.
发明人： Igor Bendik , Piero Geotti-Bianchini , Marc Heidl , Eileen Jackson , Alexander Schlifke-Poschalko
摘要： Novel biaromatic compounds, which are vitamin D analogs, processes for their preparation and cosmetic, dermatological and pharmaceutical preparations containing one or more of these compounds.
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公开(公告)号：US10470991B2
公开(公告)日：2019-11-12
申请号：US15777987
申请日：2016-12-09
申请人： DSM IP ASSETS B.V.
发明人： Stephanie Boudon , Marc Heidl , Eileen Jackson
IPC分类号： C07D207/16 , A61K8/49 , A61Q19/08 , A61K8/42
摘要： The present invention relates to novel selective 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors and the use thereof to prevent age-induced skin structure and function defects.
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公开(公告)号：US10336675B2
公开(公告)日：2019-07-02
申请号：US16061697
申请日：2016-12-14
申请人： DSM IP ASSETS B.V.
发明人： Igor Bendik , Piero Geotti-Bianchini , Marc Heidl , Eileen Jackson , Alexander Schlifke-Poschalko
摘要： Novel biaromatic compounds, which are vitamin D analogs, processes for their preparation and cosmetic, dermatological and pharmaceutical preparations containing one or more of these compounds.
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