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公开(公告)号：US10550097B2
公开(公告)日：2020-02-04
申请号：US15745754
申请日：2016-07-07
Applicant: DSM IP ASSETS B.V.
Inventor： Stéphanie Boudon , Piero Geotti-Bianchini , Marc Heidl , Eileen Jackson , Alexander Schlifke-Poschalko
IPC: C07D401/10 , A61K8/49 , A61Q19/08 , C07D223/04 , C07D265/30 , C07D211/16
Abstract: The present invention relates to novel selective 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors and the use thereof to prevent age-induced skin structure and function defects.
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公开(公告)号：US11168054B2
公开(公告)日：2021-11-09
申请号：US16061418
申请日：2016-12-14
Applicant: DSM IP ASSETS B.V.
Inventor： Igor Bendik , Piero Geotti-Bianchini , Marc Heidl , Eileen Jackson , Alexander Schlifke-Poschalko
IPC: C07C401/00 , A61K8/34 , A61Q19/08
Abstract: Novel biaromatic compounds, which are vitamin D analogs, processes for their preparation and cosmetic, dermatological and pharmaceutical preparations containing one or more of these compounds.
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公开(公告)号：US10849838B2
公开(公告)日：2020-12-01
申请号：US16062279
申请日：2016-12-14
Applicant: DSM IP ASSETS B.V.
Inventor： Igor Bendik , Piero Geotti-Bianchini , Marc Heidl , Eileen Jackson , Alexander Schlifke-Poschalko
Abstract: Novel biaromatic compounds, which are vitamin D analogs, processes for their preparation and cosmetic, dermatological and pharmaceutical preparations containing one or more of these compounds.
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Patent Agency Ranking
公开(公告)号：US11753440B2
公开(公告)日：2023-09-12
申请号：US15734751
申请日：2019-06-05
Applicant: DSM IP Assets B.V.
Inventor： Marc Heidl , Piero Geotti-Bianchini
CPC classification number: C07K5/1019 , C07K1/064 , C07K5/06156 , C07K5/0817 , C07K5/1016 , C07K5/1027
Abstract: Methods for the synthesis of arginine-containing peptides are provided. The methods include a deprotection step that minimizes the transfer of by-products deriving from cleaved sulfonyl-5 based side chain protecting groups from arginine to amino acids carrying electron rich side chains.
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公开(公告)号：US10570075B2
公开(公告)日：2020-02-25
申请号：US16062463
申请日：2016-12-14
Applicant: DSM IP ASSETS B.V.
Inventor： Igor Bendik , Piero Geotti-Bianchini , Marc Heidl , Eileen Jackson , Alexander Schlifke-Poschalko
Abstract: Novel biaromatic compounds, which are vitamin D analogs, processes for their preparation and cosmetic, dermatological and pharmaceutical preparations containing one or more of these compounds.
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公开(公告)号：US10336675B2
公开(公告)日：2019-07-02
申请号：US16061697
申请日：2016-12-14
Applicant: DSM IP ASSETS B.V.
Inventor： Igor Bendik , Piero Geotti-Bianchini , Marc Heidl , Eileen Jackson , Alexander Schlifke-Poschalko
Abstract: Novel biaromatic compounds, which are vitamin D analogs, processes for their preparation and cosmetic, dermatological and pharmaceutical preparations containing one or more of these compounds.
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公开(公告)号：US09060945B2
公开(公告)日：2015-06-23
申请号：US14369850
申请日：2012-12-28
Applicant: DSM IP Assets B.V.
Inventor： Remo Campiche , Piero Geotti-Bianchini , Hugo Ziegler , Stefan Martin Stoeckli
CPC classification number: A61K8/35 , A61K8/97 , A61K2800/10 , A61Q17/04 , A61Q19/02
Abstract: The present invention relates to a novel composition comprising danielone and derivatives thereof as well as to the use of such compositions in skin lightening. More particularly, the present invention relates to danielone and derivatives thereof for use in topical compositions for smoothening skin color irregularities, for reducing melanin formation in the human skin, for lightening/brightening human skin and/or for treatment of pigmentation disorders which comprises topically administering an effective amount of danielone and derivatives thereof to the appropriate skin area of a person in need of such beautifying agent, or treatment.
Abstract translation: 本发明涉及一种包含丹尼酮及其衍生物的新型组合物，以及这些组合物在减轻皮肤中的用途。 更具体地说，本发明涉及用于局部用于平滑皮肤颜色不规则的局部组合物的丹尼酮及其衍生物，用于减少人皮肤黑色素的形成，减轻/增亮人体皮肤和/或治疗色素沉着病，其包括局部施用 有效量的丹尼酮及其衍生物可用于需要这种美容剂的人的适当皮肤区域或治疗。
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公开(公告)号：US20150004108A1
公开(公告)日：2015-01-01
申请号：US14369850
申请日：2012-12-28
Applicant: DSM IP ASSETS B.V.
Inventor： Remo Campache , Piero Geotti-Bianchini , Hugo Ziegler
CPC classification number: A61K8/35 , A61K8/97 , A61K2800/10 , A61Q17/04 , A61Q19/02
Abstract: The present invention relates to a novel composition comprising danielone and derivatives thereof as well as to the use of such compositions in skin lightening. More particularly, the present invention relates to danielone and derivatives thereof for use in topical compositions for smoothening skin color irregularities, for reducing melanin formation in the human skin, for lightening/brightening human skin and/or for treatment of pigmentation disorders which comprises topically administering an effective amount of danielone and derivatives thereof to the appropriate skin area of a person in need of such beautifying agent, or treatment.
Abstract translation: 本发明涉及一种包含丹尼酮及其衍生物的新型组合物，以及这些组合物在减轻皮肤中的用途。 更具体地说，本发明涉及用于局部用于平滑皮肤颜色不规则的局部组合物的丹尼酮及其衍生物，用于减少人皮肤黑色素的形成，减轻/增亮人体皮肤和/或治疗色素沉着病，其包括局部施用 有效量的丹尼酮及其衍生物可用于需要这种美容剂的人的适当皮肤区域或治疗。
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