Method of Modulating Membrane Potential of a Cell
    1.
    发明申请
    Method of Modulating Membrane Potential of a Cell 有权
    调节细胞膜电位的方法

    公开(公告)号:US20090163595A1

    公开(公告)日:2009-06-25

    申请号:US12337642

    申请日:2008-12-18

    IPC分类号: A61K31/166 C12N5/06

    CPC分类号: A61K31/166

    摘要: Provided herein are methods of modulating membrane potential of a cell membrane using self-assembling compounds. Also provided herein are methods of regulating a natural voltage-dependent ion channel in a cell membrane using the self-assembling compounds disclosed herein. Further provided herein are methods of treating, preventing and/or managing a disease that is related to the abnormal membrane potential responses by using the self-assembling compounds disclosed herein.

    摘要翻译: 本文提供了使用自组装化合物调节细胞膜的膜电位的方法。 本文还提供了使用本文公开的自组装化合物来调节细胞膜中天然的依赖于电压的离子通道的方法。 本文还提供了通过使用本文公开的自组装化合物治疗,预防和/或控制与异常膜电位反应相关的疾病的方法。

    Synthetic ion channels
    3.
    发明授权

    公开(公告)号:US08378138B2

    公开(公告)日:2013-02-19

    申请号:US11959482

    申请日:2007-12-19

    申请人: Dan Yang Xiang Li

    发明人: Dan Yang Xiang Li

    IPC分类号: C07C239/08

    摘要: Provided herein are self-assembling compounds that can form ion channels in lipid bilayers or cell membranes and ion-channel-forming compositions comprising the self-assembling compounds. Also provided are methods of making and using the ion channels formed from a plurality of molecules of the self-assembling compounds. Further, provided are methods of treating or preventing conditions and diseases that are related to the dysfunction of ion channels, including chloride channels.

    Synthetic Ion Channels
    4.
    发明申请
    Synthetic Ion Channels 有权
    合成离子通道

    公开(公告)号:US20080146513A1

    公开(公告)日:2008-06-19

    申请号:US11959482

    申请日:2007-12-19

    申请人: Dan Yang Xiang Li

    发明人: Dan Yang Xiang Li

    IPC分类号: A61K38/07 C07K17/02

    摘要: Provided herein are self-assembling compounds that can form ion channels in lipid bilayers or cell membranes and ion-channel-forming compositions comprising the self-assembling compounds. Also provided are methods of making and using the ion channels formed from a plurality of molecules of the self-assembling compounds. Further, provided are methods of treating or preventing conditions and diseases that are related to the dysfunction of ion channels, including chloride channels.

    摘要翻译: 本文提供了可以在脂质双层或细胞膜中形成离子通道的自组装化合物和包含自组装化合物的离子通道形成组合物。 还提供了制造和使用由多个自组装化合物分子形成的离子通道的方法。 此外,提供了治疗或预防与离子通道功能障碍(包括氯化物通道)相关的病症和疾病的方法。

    Synthetic Ion Channels
    5.
    发明申请
    Synthetic Ion Channels 有权
    合成离子通道

    公开(公告)号:US20130244944A1

    公开(公告)日:2013-09-19

    申请号:US13731971

    申请日:2012-12-31

    摘要: Provided herein are self-assembling compounds that can form ion channels in lipid bilayers or cell membranes and ion-channel-forming compositions comprising the self-assembling compounds. Also provided are methods of making and using the ion channels formed from a plurality of molecules of the self-assembling compounds. Further, provided are methods of treating or preventing conditions and diseases that are related to the dysfunction of ion channels, including chloride channels.

    摘要翻译: 本文提供了可以在脂质双层或细胞膜中形成离子通道的自组装化合物和包含自组装化合物的离子通道形成组合物。 还提供了制造和使用由多个自组装化合物分子形成的离子通道的方法。 此外,提供了治疗或预防与离子通道功能障碍(包括氯化物通道)相关的病症和疾病的方法。

    Low cost backside illuminated CMOS image sensor package with high integration
    10.
    发明授权
    Low cost backside illuminated CMOS image sensor package with high integration 有权
    低成本背照式CMOS图像传感器封装,集成度高

    公开(公告)号:US08823126B2

    公开(公告)日:2014-09-02

    申请号:US13464939

    申请日:2012-05-04

    IPC分类号: H01L27/146

    摘要: This invention discloses a backside illuminated image sensor without the need to involve a mechanical grinding process or a chemical-mechanical planarization process in fabrication, and a fabricating method thereof. In one embodiment, an image sensor comprises a semiconductor substrate, a plurality of light sensing elements in the semiconductor substrate, and a cavity formed in the semiconductor substrate. The light sensing elements are arranged in a substantially planar manner. The cavity has a base surface overlying the light sensing elements. The presence of the cavity allows the image to reach the light sensing elements through the cavity base surface. The cavity can be fabricated by etching the semiconductor substrate. Agitation may also be used when carrying out the etching.

    摘要翻译: 本发明公开了一种背面照明图像传感器,其制造方法不需要涉及机械研磨工艺或化学机械平面化工艺。 在一个实施例中,图像传感器包括半导体衬底,半导体衬底中的多个感光元件和形成在半导体衬底中的空腔。 光感测元件以基本上平面的方式布置。 空腔具有覆盖光敏元件的基面。 空腔的存在允许图像通过空腔基面到达光感测元件。 可以通过蚀刻半导体衬底来制造空腔。 进行蚀刻时也可以使用搅拌。