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公开(公告)号:US20130165860A1
公开(公告)日:2013-06-27
申请号:US13615229
申请日:2012-09-13
申请人: Darren Doud , Randolph E. Campbell , Signe Erickson , K. Angela MacFarlane , Mike Barrett , Christina Skieller , David Batten , Greg Stine , Eugene de Juan, JR. , Douglas Sutton , Kathleen Cogan Farinas
发明人: Darren Doud , Randolph E. Campbell , Signe Erickson , K. Angela MacFarlane , Mike Barrett , Christina Skieller , David Batten , Greg Stine , Eugene de Juan, JR. , Douglas Sutton , Kathleen Cogan Farinas
CPC分类号: A61F9/0008 , A61F9/0017 , A61M5/141 , A61M5/14276 , A61M5/3202 , A61M5/3291 , A61M5/46 , A61M25/007 , A61M39/0247 , A61M2025/0031 , A61M2025/0039 , A61M2039/0081 , A61M2039/009 , A61M2039/027 , A61M2039/0276 , A61M2039/0294 , A61M2205/6045 , A61M2205/6054 , A61M2209/045 , A61M2210/0612
摘要: An injector apparatus comprises an elongate structure having one or more openings positionable near a penetrable barrier of an implantable device so as to receive fluid of the implantable device. The apparatus comprises a needle and a sheath extending over at least a portion of the needle. The elongate structure may comprise a distal tip to penetrate tissue and the penetrable barrier, and a distal opening near the tip to release therapeutic fluid into the implantable chamber. In many embodiments the distal tip, the distal opening, and the plurality of openings are separated from a stop that engages a tissue of the patient and limit penetration depth such that the distal opening and the plurality of openings are located along an axis of the implantable device to increase an efficiency of the exchange.
摘要翻译: 注射器装置包括具有一个或多个开口的细长结构,其可定位在可植入装置的可穿透屏障附近,以便容纳可植入装置的流体。 该装置包括在针的至少一部分上延伸的针和护套。 细长结构可以包括穿透组织和可穿透屏障的远端尖端,以及靠近尖端的远端开口以将治疗流体释放到可植入腔室中。 在许多实施例中,远端尖端,远侧开口和多个开口与接合患者组织的止挡分开并限制穿透深度,使得远端开口和多个开口沿着可植入的轴线 设备提高交换效率。
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公开(公告)号:US09883968B2
公开(公告)日:2018-02-06
申请号:US13615229
申请日:2012-09-13
申请人: Darren Doud , Randolph E. Campbell , Signe Erickson , K. Angela MacFarlane , Mike Barrett , Christina Skieller , David Batten , Greg Stine , Eugene de Juan, Jr. , Douglas Sutton , Kathleen Cogan Farinas
发明人: Darren Doud , Randolph E. Campbell , Signe Erickson , K. Angela MacFarlane , Mike Barrett , Christina Skieller , David Batten , Greg Stine , Eugene de Juan, Jr. , Douglas Sutton , Kathleen Cogan Farinas
CPC分类号: A61F9/0008 , A61F9/0017 , A61M5/141 , A61M5/14276 , A61M5/3202 , A61M5/3291 , A61M5/46 , A61M25/007 , A61M39/0247 , A61M2025/0031 , A61M2025/0039 , A61M2039/0081 , A61M2039/009 , A61M2039/027 , A61M2039/0276 , A61M2039/0294 , A61M2205/6045 , A61M2205/6054 , A61M2209/045 , A61M2210/0612
摘要: An injector apparatus comprises an elongate structure having one or more openings positionable near a penetrable barrier of an implantable device so as to receive fluid of the implantable device. The apparatus comprises a needle and a sheath extending over at least a portion of the needle. The elongate structure may comprise a distal tip to penetrate tissue and the penetrable barrier, and a distal opening near the tip to release therapeutic fluid into the implantable chamber. In many embodiments the distal tip, the distal opening, and the plurality of openings are separated from a stop that engages a tissue of the patient and limit penetration depth such that the distal opening and the plurality of openings are located along an axis of the implantable device to increase an efficiency of the exchange.
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公开(公告)号:US20130324918A1
公开(公告)日:2013-12-05
申请号:US13814461
申请日:2011-08-05
申请人: Eugene de Juan, JR. , Yair Alster , Kathleen Cogan Farinas , K. Angela MacFarlane , Cary J. Reich , Randolph E. Campbell , Darren Doud , Signe Erickson , Mike Barrett , David Batten , Christina Skieller , Greg Stine
发明人: Eugene de Juan, JR. , Yair Alster , Kathleen Cogan Farinas , K. Angela MacFarlane , Cary J. Reich , Randolph E. Campbell , Darren Doud , Signe Erickson , Mike Barrett , David Batten , Christina Skieller , Greg Stine
IPC分类号: A61F9/00
CPC分类号: A61F9/0017 , A61F9/0008 , A61M5/14276 , A61M5/178 , A61M5/31 , A61M5/32 , A61M5/46 , A61M39/0208 , A61M39/0247 , A61M2039/027 , A61M2039/0276
摘要: Methods and apparatus provide a therapeutic fluid to devices implanted in the body, for example to containers of devices implanted in the eye of a patient. The methods and apparatus may comprise an injector to increase an amount of therapeutic agent injected into the device implanted in the eye, or a structure to receive the therapeutic fluid within the device implanted in the eye, or combinations thereof. The device implanted in the eye may comprise a reservoir chamber having a fluid with a density different than the therapeutic fluid, and the apparatus can be adapted to at least partially separate the implanted device fluid from therapeutic fluid within the reservoir chamber to increase and amount of therapeutic fluid placed in the reservoir chamber.
摘要翻译: 方法和装置为植入体内的装置提供治疗性液体,例如植入患者眼中的装置的容器。 所述方法和装置可包括注射器以增加注入植入眼中的装置中的治疗剂的量,或用于接收植入眼睛内的装置中的治疗流体的结构或其组合。 植入眼睛中的装置可以包括具有密度不同于治疗流体的流体的储存室,并且该装置可以适于至少部分地将植入的装置流体与储存室内的治疗流体分开以增加和量 治疗液放置在储存室中。
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公开(公告)号:US09033911B2
公开(公告)日:2015-05-19
申请号:US13814461
申请日:2011-08-05
申请人: Eugene de Juan, Jr. , Yair Alster , Kathleen Cogan Farinas , K. Angela MacFarlane , Cary J. Reich , Randolph E. Campbell , Darren Doud , Signe Erickson , Mike Barrett , David Batten , Christina Skieller , Greg Stine
发明人: Eugene de Juan, Jr. , Yair Alster , Kathleen Cogan Farinas , K. Angela MacFarlane , Cary J. Reich , Randolph E. Campbell , Darren Doud , Signe Erickson , Mike Barrett , David Batten , Christina Skieller , Greg Stine
CPC分类号: A61F9/0017 , A61F9/0008 , A61M5/14276 , A61M5/178 , A61M5/31 , A61M5/32 , A61M5/46 , A61M39/0208 , A61M39/0247 , A61M2039/027 , A61M2039/0276
摘要: Methods and apparatus provide a therapeutic fluid to devices implanted in the body, for example to containers of devices implanted in the eye of a patient. The methods and apparatus may comprise an injector to increase an amount of therapeutic agent injected into the device implanted in the eye, or a structure to receive the therapeutic fluid within the device implanted in the eye, or combinations thereof. The device implanted in the eye may comprise a reservoir chamber having a fluid with a density different than the therapeutic fluid, and the apparatus can be adapted to at least partially separate the implanted device fluid from therapeutic fluid within the reservoir chamber to increase and amount of therapeutic fluid placed in the reservoir chamber.
摘要翻译: 方法和装置为植入体内的装置提供治疗性液体,例如植入患者眼中的装置的容器。 所述方法和装置可包括注射器以增加注入植入眼中的装置中的治疗剂的量,或用于接收植入眼睛内的装置中的治疗流体的结构或其组合。 植入眼睛中的装置可以包括具有密度不同于治疗流体的流体的储存室,并且该装置可以适于至少部分地将植入的装置流体与储存室内的治疗流体分开以增加和量 治疗液放置在储存室中。
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公开(公告)号:US07887556B2
公开(公告)日:2011-02-15
申请号:US10288581
申请日:2002-11-04
申请人: John B. Simpson , Himanshu Patel , Greg Stine
发明人: John B. Simpson , Himanshu Patel , Greg Stine
IPC分类号: A61B17/22
CPC分类号: A61B17/320758 , A61B8/12 , A61B17/2202 , A61B17/320725 , A61B17/320783 , A61B2017/00685 , A61B2017/2927 , A61B2017/320032 , A61B2017/320791
摘要: A method of removing material from a blood flow lumen generally includes providing a device having a cutting element and an opening, advancing the device through the blood flow lumen to a site where material is to be removed, forcing the opening toward a wall of the site where material is to be removed, and moving the cutting element and the opening so that material in the blood flow lumen is cut by the cutting element and directed into the opening for removal as the cutting element and opening are moved through the blood flow lumen. In some embodiments, the device may be deflected or bent to force the opening toward a wall to remove material. The cutting element may be rotatable and may have an axis that is movable, that is not parallel to the longitudinal axis of the device, or both. In some embodiments, the cutting element is movable between retracted and deployed positions for advancing the device to a site for treatment and for removing material, respectively.
摘要翻译: 从血流腔中去除材料的方法通常包括提供具有切割元件和开口的装置,将装置通过血流腔前进到要除去材料的部位,迫使开口朝向部位的壁 其中要去除材料,并且移动切割元件和开口,使得当切割元件和开口移动通过血流腔时,通过切割元件切割血流腔中的材料并将其引导到用于移除的开口中。 在一些实施例中,该装置可能被偏转或弯曲以迫使开口朝向壁以移除材料。 切割元件可以是可旋转的并且可以具有可移动的轴线,其不平行于装置的纵向轴线或两者。 在一些实施例中,切割元件可在缩回和展开位置之间移动,以将装置分别推进到处理场所和用于移除材料。
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公开(公告)号:US20120330336A1
公开(公告)日:2012-12-27
申请号:US13536497
申请日:2012-06-28
申请人: John B. Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael H. Rosenthal , Mehrdad Farhangnia
发明人: John B. Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael H. Rosenthal , Mehrdad Farhangnia
IPC分类号: A61B17/22
CPC分类号: A61B17/320758 , A61B10/04 , A61B17/32075 , A61B17/320783 , A61B2010/0225 , A61B2017/00685 , A61B2017/320032 , A61B2017/320791
摘要: A method of removing material from a blood flow lumen includes providing a device having a cutting element and an opening, the cutting element being movable relative to the opening. The method then includes advancing the device through a patient's vascular system to the blood flow lumen. Finally, the method involves moving the cutting element and the opening relative to the blood flow lumen so that a continuous piece of material is severed by the cutting element and directed into the opening as the cutting element and opening move through the blood flow lumen, the continuous piece of severed material being directed into the device for removal from the patient. The method may include providing a device having a rotatable cutter that, in some embodiments, is not parallel to the longitudinal axis of the device, is movable, has retracted and deployed positions, or any combination thereof.
摘要翻译: 从血流腔去除材料的方法包括提供具有切割元件和开口的装置,所述切割元件可相对于所述开口移动。 该方法然后包括将装置通过患者的血管系统推进到血流腔。 最后,该方法包括相对于血液流动腔移动切割元件和开口,使得当切割元件和开口移动通过血流腔时,连续片材被切割元件切断并引导到开口中, 连续切断的材料被引导到装置中以从患者身上取出。 该方法可以包括提供具有可旋转切割器的装置,其在一些实施例中不平行于装置的纵向轴线,是可移动的,具有缩回和展开位置或其任何组合。
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公开(公告)号:US20100198240A1
公开(公告)日:2010-08-05
申请号:US12757291
申请日:2010-04-09
申请人: John B. Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael H. Rosenthal , Mehrdad Farhangnia
发明人: John B. Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael H. Rosenthal , Mehrdad Farhangnia
CPC分类号: A61B17/320758 , A61B10/04 , A61B17/32075 , A61B17/320783 , A61B2010/0225 , A61B2017/00685 , A61B2017/320032 , A61B2017/320791
摘要: A method of removing material from a blood flow lumen includes providing a device having a cutting element and an opening, the cutting element being movable relative to the opening. The method then includes advancing the device through a patient's vascular system to the blood flow lumen. Finally, the method involves moving the cutting element and the opening relative to the blood flow lumen so that a continuous piece of material is severed by the cutting element and directed into the opening as the cutting element and opening move through the blood flow lumen, the continuous piece of severed material being directed into the device for removal from the patient. The method may include providing a device having a rotatable cutter that, in some embodiments, is not parallel to the longitudinal axis of the device, is movable, has retracted and deployed positions, or any combination thereof. The method may further include forcing the opening toward the wall of the vascular site after the advancing step and before the moving step.
摘要翻译: 从血流腔去除材料的方法包括提供具有切割元件和开口的装置,所述切割元件可相对于所述开口移动。 该方法然后包括将装置通过患者的血管系统推进到血流腔。 最后,该方法包括相对于血液流动腔移动切割元件和开口,使得当切割元件和开口移动通过血流腔时,连续片材被切割元件切断并引导到开口中, 连续切断的材料被引导到装置中以从患者身上取出。 该方法可以包括提供具有可旋转切割器的装置,其在一些实施例中不平行于装置的纵向轴线,是可移动的,具有缩回和展开位置或其任何组合。 该方法还可以包括在推进步骤之后和移动步骤之前迫使开口朝向血管部位的壁。
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公开(公告)号:US07708749B2
公开(公告)日:2010-05-04
申请号:US11012876
申请日:2004-12-14
申请人: John B. Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael H. Rosenthal , Mehrdad Farhangnia
发明人: John B. Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael H. Rosenthal , Mehrdad Farhangnia
CPC分类号: A61B17/320758 , A61B10/04 , A61B17/32075 , A61B17/320783 , A61B2010/0225 , A61B2017/00685 , A61B2017/320032 , A61B2017/320791
摘要: A method of removing material from a blood flow lumen includes providing a device having a cutting element and an opening, the cutting element being movable relative to the opening. The method then includes advancing the device through a patient's vascular system to the blood flow lumen. Finally, the method involves moving the cutting element and the opening relative to the blood flow lumen so that a continuous piece of material is severed by the cutting element and directed into the opening as the cutting element and opening move through the blood flow lumen, the continuous piece of severed material being directed into the device for removal from the patient. The method may include providing a device having a rotatable cutter that, in some embodiments, is not parallel to the longitudinal axis of the device, is movable, has retracted and deployed positions, or any combination thereof. The method may further include forcing the opening toward the wall of the vascular site after the advancing step and before the moving step.
摘要翻译: 从血流腔去除材料的方法包括提供具有切割元件和开口的装置,所述切割元件可相对于所述开口移动。 该方法然后包括将装置通过患者的血管系统推进到血流腔。 最后,该方法包括相对于血液流动腔移动切割元件和开口,使得当切割元件和开口移动通过血流腔时,连续片材被切割元件切断并引导到开口中, 连续切断的材料被引导到装置中以从患者身上取出。 该方法可以包括提供具有可旋转切割器的装置,其在一些实施例中不平行于装置的纵向轴线,是可移动的,具有缩回和展开位置或其任何组合。 该方法还可以包括在推进步骤之后和移动步骤之前迫使开口朝向血管部位的壁。
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公开(公告)号:US20050222663A1
公开(公告)日:2005-10-06
申请号:US11012876
申请日:2004-12-14
申请人: John Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael Rosenthal , Mehrdad Farhangnia
发明人: John Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael Rosenthal , Mehrdad Farhangnia
CPC分类号: A61B17/320758 , A61B10/04 , A61B17/32075 , A61B17/320783 , A61B2010/0225 , A61B2017/00685 , A61B2017/320032 , A61B2017/320791
摘要: A method of removing material from a blood flow lumen includes providing a device having a cutting element and an opening, the cutting element being movable relative to the opening. The method then includes advancing the device through a patient's vascular system to the blood flow lumen. Finally, the method involves moving the cutting element and the opening relative to the blood flow lumen so that a continuous piece of material is severed by the cutting element and directed into the opening as the cutting element and opening move through the blood flow lumen, the continuous piece of severed material being directed into the device for removal from the patient. The method may include providing a device having a rotatable cutter that, in some embodiments, is not parallel to the longitudinal axis of the device, is movable, has retracted and deployed positions, or any combination thereof. The method may further include forcing the opening toward the wall of the vascular site after the advancing step and before the moving step.
摘要翻译: 从血流腔去除材料的方法包括提供具有切割元件和开口的装置,所述切割元件可相对于所述开口移动。 该方法然后包括将装置通过患者的血管系统推进到血流腔。 最后,该方法包括相对于血液流动腔移动切割元件和开口,使得当切割元件和开口移动通过血流腔时,连续片材被切割元件切断并引导到开口中, 连续切断的材料被引导到装置中以从患者身上取出。 该方法可以包括提供具有可旋转切割器的装置,其在一些实施例中不平行于装置的纵向轴线,是可移动的,具有缩回和展开位置或其任何组合。 该方法还可以包括在推进步骤之后和移动步骤之前迫使开口朝向血管部位的壁。
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公开(公告)号:US08911459B2
公开(公告)日:2014-12-16
申请号:US13536497
申请日:2012-06-28
申请人: John B. Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael H. Rosenthal , Mehrdad Farhangnia
发明人: John B. Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael H. Rosenthal , Mehrdad Farhangnia
CPC分类号: A61B17/320758 , A61B10/04 , A61B17/32075 , A61B17/320783 , A61B2010/0225 , A61B2017/00685 , A61B2017/320032 , A61B2017/320791
摘要: A method of removing material from a blood flow lumen includes providing a device having a cutting element and an opening, the cutting element being movable relative to the opening. The method then includes advancing the device through a patient's vascular system to the blood flow lumen. Finally, the method involves moving the cutting element and the opening relative to the blood flow lumen so that a continuous piece of material is severed by the cutting element and directed into the opening as the cutting element and opening move through the blood flow lumen, the continuous piece of severed material being directed into the device for removal from the patient. The method may include providing a device having a rotatable cutter that, in some embodiments, is not parallel to the longitudinal axis of the device, is movable, has retracted and deployed positions, or any combination thereof.
摘要翻译: 从血流腔去除材料的方法包括提供具有切割元件和开口的装置,所述切割元件可相对于所述开口移动。 该方法然后包括将装置通过患者的血管系统推进到血流腔。 最后,该方法包括相对于血液流动腔移动切割元件和开口,使得当切割元件和开口移动通过血流腔时,连续片材被切割元件切断并引导到开口中, 连续切断的材料被引导到装置中以从患者身上取出。 该方法可以包括提供具有可旋转切割器的装置,其在一些实施例中不平行于装置的纵向轴线,是可移动的,具有缩回和展开位置或其任何组合。
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