公开(公告)号：US20130165860A1

公开(公告)日：2013-06-27

申请号：US13615229

申请日：2012-09-13

申请人： Darren Doud ,  Randolph E. Campbell ,  Signe Erickson ,  K. Angela MacFarlane ,  Mike Barrett ,  Christina Skieller ,  David Batten ,  Greg Stine ,  Eugene de Juan, JR. ,  Douglas Sutton ,  Kathleen Cogan Farinas

发明人： Darren Doud ,  Randolph E. Campbell ,  Signe Erickson ,  K. Angela MacFarlane ,  Mike Barrett ,  Christina Skieller ,  David Batten ,  Greg Stine ,  Eugene de Juan, JR. ,  Douglas Sutton ,  Kathleen Cogan Farinas

IPC分类号： A61M5/46 ,  A61F9/00

CPC分类号： A61F9/0008 ,  A61F9/0017 ,  A61M5/141 ,  A61M5/14276 ,  A61M5/3202 ,  A61M5/3291 ,  A61M5/46 ,  A61M25/007 ,  A61M39/0247 ,  A61M2025/0031 ,  A61M2025/0039 ,  A61M2039/0081 ,  A61M2039/009 ,  A61M2039/027 ,  A61M2039/0276 ,  A61M2039/0294 ,  A61M2205/6045 ,  A61M2205/6054 ,  A61M2209/045 ,  A61M2210/0612

摘要： An injector apparatus comprises an elongate structure having one or more openings positionable near a penetrable barrier of an implantable device so as to receive fluid of the implantable device. The apparatus comprises a needle and a sheath extending over at least a portion of the needle. The elongate structure may comprise a distal tip to penetrate tissue and the penetrable barrier, and a distal opening near the tip to release therapeutic fluid into the implantable chamber. In many embodiments the distal tip, the distal opening, and the plurality of openings are separated from a stop that engages a tissue of the patient and limit penetration depth such that the distal opening and the plurality of openings are located along an axis of the implantable device to increase an efficiency of the exchange.

摘要翻译： 注射器装置包括具有一个或多个开口的细长结构，其可定位在可植入装置的可穿透屏障附近，以便容纳可植入装置的流体。 该装置包括在针的至少一部分上延伸的针和护套。 细长结构可以包括穿透组织和可穿透屏障的远端尖端，以及靠近尖端的远端开口以将治疗流体释放到可植入腔室中。 在许多实施例中，远端尖端，远侧开口和多个开口与接合患者组织的止挡分开并限制穿透深度，使得远端开口和多个开口沿着可植入的轴线 设备提高交换效率。

公开(公告)号：US09883968B2

公开(公告)日：2018-02-06

申请号：US13615229

申请日：2012-09-13

申请人： Darren Doud ,  Randolph E. Campbell ,  Signe Erickson ,  K. Angela MacFarlane ,  Mike Barrett ,  Christina Skieller ,  David Batten ,  Greg Stine ,  Eugene de Juan, Jr. ,  Douglas Sutton ,  Kathleen Cogan Farinas

发明人： Darren Doud ,  Randolph E. Campbell ,  Signe Erickson ,  K. Angela MacFarlane ,  Mike Barrett ,  Christina Skieller ,  David Batten ,  Greg Stine ,  Eugene de Juan, Jr. ,  Douglas Sutton ,  Kathleen Cogan Farinas

IPC分类号： A61F9/00 ,  A61M25/00 ,  A61M39/02 ,  A61M5/14 ,  A61M5/32 ,  A61M5/46 ,  A61M39/00 ,  A61M5/142

CPC分类号： A61F9/0008 ,  A61F9/0017 ,  A61M5/141 ,  A61M5/14276 ,  A61M5/3202 ,  A61M5/3291 ,  A61M5/46 ,  A61M25/007 ,  A61M39/0247 ,  A61M2025/0031 ,  A61M2025/0039 ,  A61M2039/0081 ,  A61M2039/009 ,  A61M2039/027 ,  A61M2039/0276 ,  A61M2039/0294 ,  A61M2205/6045 ,  A61M2205/6054 ,  A61M2209/045 ,  A61M2210/0612

摘要： An injector apparatus comprises an elongate structure having one or more openings positionable near a penetrable barrier of an implantable device so as to receive fluid of the implantable device. The apparatus comprises a needle and a sheath extending over at least a portion of the needle. The elongate structure may comprise a distal tip to penetrate tissue and the penetrable barrier, and a distal opening near the tip to release therapeutic fluid into the implantable chamber. In many embodiments the distal tip, the distal opening, and the plurality of openings are separated from a stop that engages a tissue of the patient and limit penetration depth such that the distal opening and the plurality of openings are located along an axis of the implantable device to increase an efficiency of the exchange.

公开(公告)号：US20130324918A1

公开(公告)日：2013-12-05

申请号：US13814461

申请日：2011-08-05

申请人： Eugene de Juan, JR. ,  Yair Alster ,  Kathleen Cogan Farinas ,  K. Angela MacFarlane ,  Cary J. Reich ,  Randolph E. Campbell ,  Darren Doud ,  Signe Erickson ,  Mike Barrett ,  David Batten ,  Christina Skieller ,  Greg Stine

发明人： Eugene de Juan, JR. ,  Yair Alster ,  Kathleen Cogan Farinas ,  K. Angela MacFarlane ,  Cary J. Reich ,  Randolph E. Campbell ,  Darren Doud ,  Signe Erickson ,  Mike Barrett ,  David Batten ,  Christina Skieller ,  Greg Stine

IPC分类号： A61F9/00

CPC分类号： A61F9/0017 ,  A61F9/0008 ,  A61M5/14276 ,  A61M5/178 ,  A61M5/31 ,  A61M5/32 ,  A61M5/46 ,  A61M39/0208 ,  A61M39/0247 ,  A61M2039/027 ,  A61M2039/0276

摘要： Methods and apparatus provide a therapeutic fluid to devices implanted in the body, for example to containers of devices implanted in the eye of a patient. The methods and apparatus may comprise an injector to increase an amount of therapeutic agent injected into the device implanted in the eye, or a structure to receive the therapeutic fluid within the device implanted in the eye, or combinations thereof. The device implanted in the eye may comprise a reservoir chamber having a fluid with a density different than the therapeutic fluid, and the apparatus can be adapted to at least partially separate the implanted device fluid from therapeutic fluid within the reservoir chamber to increase and amount of therapeutic fluid placed in the reservoir chamber.

摘要翻译： 方法和装置为植入体内的装置提供治疗性液体，例如植入患者眼中的装置的容器。 所述方法和装置可包括注射器以增加注入植入眼中的装置中的治疗剂的量，或用于接收植入眼睛内的装置中的治疗流体的结构或其组合。 植入眼睛中的装置可以包括具有密度不同于治疗流体的流体的储存室，并且该装置可以适于至少部分地将植入的装置流体与储存室内的治疗流体分开以增加和量 治疗液放置在储存室中。

公开(公告)号：US09033911B2

公开(公告)日：2015-05-19

申请号：US13814461

申请日：2011-08-05

申请人： Eugene de Juan, Jr. ,  Yair Alster ,  Kathleen Cogan Farinas ,  K. Angela MacFarlane ,  Cary J. Reich ,  Randolph E. Campbell ,  Darren Doud ,  Signe Erickson ,  Mike Barrett ,  David Batten ,  Christina Skieller ,  Greg Stine

发明人： Eugene de Juan, Jr. ,  Yair Alster ,  Kathleen Cogan Farinas ,  K. Angela MacFarlane ,  Cary J. Reich ,  Randolph E. Campbell ,  Darren Doud ,  Signe Erickson ,  Mike Barrett ,  David Batten ,  Christina Skieller ,  Greg Stine

IPC分类号： A61F9/00 ,  A61M5/142 ,  A61M5/178 ,  A61M5/31 ,  A61M39/02

CPC分类号： A61F9/0017 ,  A61F9/0008 ,  A61M5/14276 ,  A61M5/178 ,  A61M5/31 ,  A61M5/32 ,  A61M5/46 ,  A61M39/0208 ,  A61M39/0247 ,  A61M2039/027 ,  A61M2039/0276

摘要： Methods and apparatus provide a therapeutic fluid to devices implanted in the body, for example to containers of devices implanted in the eye of a patient. The methods and apparatus may comprise an injector to increase an amount of therapeutic agent injected into the device implanted in the eye, or a structure to receive the therapeutic fluid within the device implanted in the eye, or combinations thereof. The device implanted in the eye may comprise a reservoir chamber having a fluid with a density different than the therapeutic fluid, and the apparatus can be adapted to at least partially separate the implanted device fluid from therapeutic fluid within the reservoir chamber to increase and amount of therapeutic fluid placed in the reservoir chamber.

摘要翻译： 方法和装置为植入体内的装置提供治疗性液体，例如植入患者眼中的装置的容器。 所述方法和装置可包括注射器以增加注入植入眼中的装置中的治疗剂的量，或用于接收植入眼睛内的装置中的治疗流体的结构或其组合。 植入眼睛中的装置可以包括具有密度不同于治疗流体的流体的储存室，并且该装置可以适于至少部分地将植入的装置流体与储存室内的治疗流体分开以增加和量 治疗液放置在储存室中。

公开(公告)号：US10398592B2

公开(公告)日：2019-09-03

申请号：US14129200

申请日：2012-06-28

申请人： Signe Erickson ,  Darren Doud ,  Eugene de Juan, Jr. ,  Yair Alster ,  Cary J. Reich ,  Kathleen Cogan Farinas

发明人： Signe Erickson ,  Darren Doud ,  Eugene de Juan, Jr. ,  Yair Alster ,  Cary J. Reich ,  Kathleen Cogan Farinas

IPC分类号： A61M35/00 ,  A61F9/00 ,  A61B10/00

摘要： An apparatus to treat a patient comprises a container to receive fluid of a device implanted in the eye. The fluid of the device can be analyzed to determine a component of the vitreous humor of the eye.

公开(公告)号：US20140221941A1

公开(公告)日：2014-08-07

申请号：US14129200

申请日：2012-06-28

申请人： Signe Erickson ,  Darren Doud ,  Eugene de Juan, JR. ,  Yair Alster ,  Cary J. Reich ,  Kathleen Cogan Farinas

发明人： Signe Erickson ,  Darren Doud ,  Eugene de Juan, JR. ,  Yair Alster ,  Cary J. Reich ,  Kathleen Cogan Farinas

IPC分类号： A61F9/00

CPC分类号： A61F9/0017 ,  A61B10/0045 ,  A61F2250/0067

摘要： An apparatus to treat a patient comprises a container to receive fluid of a device implanted in the eye. The fluid of the device can be analyzed to determine a component of the vitreous humor of the eye.

摘要翻译： 用于治疗患者的装置包括容纳植入眼中的装置的流体的容器。 可以分析装置的流体以确定眼睛玻璃体液的一个组成部分。

公开(公告)号：US20100130996A1

公开(公告)日：2010-05-27

申请号：US12578204

申请日：2009-10-13

申请人： Darren Doud ,  Tomislav Huljev ,  Ralph McNall ,  Brandon Fell ,  Priyanshu Gupta ,  Ryan Olivera ,  Thomas C. Pham

发明人： Darren Doud ,  Tomislav Huljev ,  Ralph McNall ,  Brandon Fell ,  Priyanshu Gupta ,  Ryan Olivera ,  Thomas C. Pham

IPC分类号： A61B17/22

CPC分类号： A61B17/320783 ,  A61B2017/003 ,  A61B2017/00318 ,  A61B2017/00331 ,  A61B2017/00389 ,  A61B2017/00469 ,  A61B2017/00778 ,  A61B2017/22038 ,  A61B2017/320791 ,  A61M25/0152 ,  A61M2025/0161

摘要： A catheter for performing a procedure at a treatment site in the lumen of a blood vessel. The catheter includes an elongate tubular shaft having a proximal bend, a distal bend and a hinge element. A distal portion of the shaft includes a window extending through the sidewall of the shaft between the hinge element and the distal end of the elongate tubular shaft. A working element is disposed within the lumen of the elongate tubular shaft and is configured for performing the procedure through the window at the treatment site. The bends and hinge element are configured to urge the window against a wall of the vessel at the treatment site.

摘要翻译： 一种用于在血管内腔的治疗部位进行手术的导管。 导管包括具有近端弯曲部，远端弯曲部和铰链部件的细长管状轴。 轴的远侧部分包括在铰链元件和细长管状轴的远端之间延伸穿过轴的侧壁的窗口。 工作元件设置在细长管状轴的内腔内，并被构造成用于在治疗部位通过窗口执行该过程。 弯曲和铰链元件构造成在处理部位将窗户推向容器的壁。

公开(公告)号：US20060235334A1

公开(公告)日：2006-10-19

申请号：US11455995

申请日：2006-06-19

申请人： Tim Corvi ,  Stephen Boyd ,  Brett Follmer ,  John Stine ,  David Snow ,  Darren Doud

发明人： Tim Corvi ,  Stephen Boyd ,  Brett Follmer ,  John Stine ,  David Snow ,  Darren Doud

IPC分类号： A61B10/00

CPC分类号： A61B10/0275 ,  A61B10/04 ,  A61B17/320783 ,  A61B2017/320064 ,  A61B2017/320791

摘要： Catheters, kits, and methods are provided for removing material from a body lumen. The catheters and methods may be used in a variety of body lumens, including but not limited to coronary and other arteries. In general, the catheter has a cutting element that cuts material while the material is engaged by a material capture device on the catheter body. Preferably, the material capture device tensions the material during cutting, which reduces the amount of cutting force required. The material capture device typically follows a path that draws material into the catheter body. Preferably, but not necessarily, the material capture device may be arranged on the catheter body to advance along a path outwardly from the catheter body into the material and then inwardly towards the catheter body to tension the material. The cutting element on the catheter body moves between a first position and a second position to cut the material while in tension.

公开(公告)号：US09687266B2

公开(公告)日：2017-06-27

申请号：US12768281

申请日：2010-04-27

申请人： John Robert Moberg ,  Alex Yang ,  Christopher B. Brodeur ,  William Joseph Whealon ,  Kee Lee ,  Phyllis Yuen ,  Darren Doud

发明人： John Robert Moberg ,  Alex Yang ,  Christopher B. Brodeur ,  William Joseph Whealon ,  Kee Lee ,  Phyllis Yuen ,  Darren Doud

IPC分类号： A61B17/22 ,  A61B17/3207 ,  A61B17/32

CPC分类号： A61B17/320758 ,  A61B17/320783 ,  A61B2017/320004 ,  A61B2017/320791

摘要： The present invention provides an atherectomy catheter which has a cutting element that is able to cut both soft tissue and hard tissue, and methods of cutting material from a blood vessel lumen using a rotating cutting element. The cutting element has a sharp cutting edge that surrounds a cup-shaped surface and at least one surface of abrasive material. The cup-shaped surface directs the cut material into a tissue chamber. The cutting edge and the cup-shaped surface together are well suited to cut and remove relatively soft tissue from the blood vessel. The abrasive material surface in combination with the cutting element is well suited to abrade and remove hard material from the blood vessel.

公开(公告)号：US08784440B2

公开(公告)日：2014-07-22

申请号：US12325797

申请日：2008-12-01

申请人： Kee Lee ,  Phyllis Yuen ,  Darren Doud

发明人： Kee Lee ,  Phyllis Yuen ,  Darren Doud

IPC分类号： A61B17/3207

CPC分类号： A61B17/320758 ,  A61B17/320725 ,  A61B17/32075 ,  A61B17/320783 ,  A61B2017/320791

摘要： A catheter is provided, which includes a cutting element having one or more raised elements. The cutting element has a cup-shaped surface at the distal end that may be smooth and continuous except for the raised elements.

摘要翻译： 提供了一种导管，其包括具有一个或多个凸起元件的切割元件。 切割元件具有在远端处的杯形表面，除了凸起元件之外，其可以是平滑和连续的。