-
公开(公告)号:US20110160233A1
公开(公告)日:2011-06-30
申请号:US11960298
申请日:2007-12-19
申请人: David A. Betebenner , Clarence J. Maring , Todd W. Rockway , Curt S. Cooper , David D. Anderson , Rolf Wagner , Rong Zhang , Akhteruzzaman Molla , Hongmei Mo , Tami J. Pilot-Matias , Sherie VL. Masse , Robert J. Carrick , Wenping He , Liangjun Lu
发明人: David A. Betebenner , Clarence J. Maring , Todd W. Rockway , Curt S. Cooper , David D. Anderson , Rolf Wagner , Rong Zhang , Akhteruzzaman Molla , Hongmei Mo , Tami J. Pilot-Matias , Sherie VL. Masse , Robert J. Carrick , Wenping He , Liangjun Lu
IPC分类号: A61K31/519 , C07D471/14 , A61P31/14
CPC分类号: C07D471/04 , C07D239/94 , C07D487/04 , C07D487/14 , C07D519/00
摘要: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
摘要翻译: 公开了有效抑制丙型肝炎病毒(“HCV”)或其他病毒复制的化合物。 本发明还涉及包含这些化合物的组合物,这些化合物与其它抗病毒剂或治疗剂的共同配制或共同给药,用于合成这些化合物的方法和中间体,以及使用这些化合物治疗 HCV或其他病毒感染。
-
公开(公告)号:US07763731B2
公开(公告)日:2010-07-27
申请号:US11613836
申请日:2006-12-20
申请人: Todd W. Rockway , David A. Betebenner , Allan C. Krueger , Nobuhiko Iwasaki , Curt S. Cooper , David D. Anderson , Dale J. Kempf , Darold L. Madigan , Christopher E. Motter , Jason P. Shanley , Michael D. Tufano , Rolf Wagner , Rong Zhang , Akhteruzzaman Molla , Hongmei Mo , Tami J. Pilot-Matias , Sherie VL. Masse , Robert J. Carrick , Wenping He , Liangjun Lu
发明人: Todd W. Rockway , David A. Betebenner , Allan C. Krueger , Nobuhiko Iwasaki , Curt S. Cooper , David D. Anderson , Dale J. Kempf , Darold L. Madigan , Christopher E. Motter , Jason P. Shanley , Michael D. Tufano , Rolf Wagner , Rong Zhang , Akhteruzzaman Molla , Hongmei Mo , Tami J. Pilot-Matias , Sherie VL. Masse , Robert J. Carrick , Wenping He , Liangjun Lu
IPC分类号: C07D471/02
CPC分类号: C07D471/04
摘要: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
摘要翻译: 公开了有效抑制丙型肝炎病毒(“HCV”)或其他病毒复制的化合物。 本发明还涉及包含这些化合物的组合物,这些化合物与其它抗病毒剂或治疗剂的共同配制或共同给药,用于合成这些化合物的方法和中间体,以及使用这些化合物治疗 HCV或其他病毒感染。
-
公开(公告)号:US07910595B2
公开(公告)日:2011-03-22
申请号:US11613810
申请日:2006-12-20
申请人: David A. Betebenner , David A. DeGoey , Clarence J. Maring , Allan C. Krueger , Nobuhiko Iwasaki , Todd W. Rockway , Curt S. Cooper , David D. Anderson , Pamela L. Donner , Brian E. Green , Dale J. Kempf , Dachun Liu , Keith F. McDaniel , Darold L. Madigan , Christopher E. Motter , John K. Pratt , Jason P. Shanley , Michael D. Tufano , Rolf Wagner , Rong Zhang , Akhteruzzaman Molla , Hongmei Mo , Tami J. Pilot-Matias , Sherie V L. Masse , Robert J. Carrick , Wenping He , Liangjun Lu , David J. Grampovnik
发明人: David A. Betebenner , David A. DeGoey , Clarence J. Maring , Allan C. Krueger , Nobuhiko Iwasaki , Todd W. Rockway , Curt S. Cooper , David D. Anderson , Pamela L. Donner , Brian E. Green , Dale J. Kempf , Dachun Liu , Keith F. McDaniel , Darold L. Madigan , Christopher E. Motter , John K. Pratt , Jason P. Shanley , Michael D. Tufano , Rolf Wagner , Rong Zhang , Akhteruzzaman Molla , Hongmei Mo , Tami J. Pilot-Matias , Sherie V L. Masse , Robert J. Carrick , Wenping He , Liangjun Lu , David J. Grampovnik
IPC分类号: C07D471/04 , A01N31/519 , A61P31/12
CPC分类号: C07D471/04 , C07D495/04 , C07D513/04
摘要: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
摘要翻译: 公开了有效抑制丙型肝炎病毒(“HCV”)或其他病毒复制的化合物。 本发明还涉及包含这些化合物的组合物,这些化合物与其它抗病毒剂或治疗剂的共同配制或共同给药,用于合成这些化合物的方法和中间体,以及使用这些化合物治疗 HCV或其他病毒感染。
-
公开(公告)号:US08236950B2
公开(公告)日:2012-08-07
申请号:US11960298
申请日:2007-12-19
申请人: David A. Betebenner , Clarence J. Maring , Todd W. Rockway , Curt S. Cooper , David D. Anderson , Rolf Wagner , Rong Zhang , Akhteruzzaman Molla , Hongmei Mo , Tami J. Pilot-Matias , Sherie V L. Masse , Robert J. Carrick , Wenping He , Liangjun Lu
发明人: David A. Betebenner , Clarence J. Maring , Todd W. Rockway , Curt S. Cooper , David D. Anderson , Rolf Wagner , Rong Zhang , Akhteruzzaman Molla , Hongmei Mo , Tami J. Pilot-Matias , Sherie V L. Masse , Robert J. Carrick , Wenping He , Liangjun Lu
IPC分类号: C07D491/02
CPC分类号: C07D471/04 , C07D239/94 , C07D487/04 , C07D487/14 , C07D519/00
摘要: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
摘要翻译: 公开了有效抑制丙型肝炎病毒(“HCV”)或其他病毒复制的化合物。 本发明还涉及包含这些化合物的组合物,这些化合物与其它抗病毒剂或治疗剂的共同配制或共同给药,用于合成这些化合物的方法和中间体,以及使用这些化合物治疗 HCV或其他病毒感染。
-
公开(公告)号:US07915411B2
公开(公告)日:2011-03-29
申请号:US11613825
申请日:2006-12-20
申请人: David A. Betebenner , David A. DeGoey , Clarence J. Maring , Allan C. Krueger , Nobuhiko Iwasaki , Todd W. Rockway , Curt S. Cooper , David D. Anderson , Pamela L. Donner , Brian E. Green , Dale J. Kempf , Dachun Liu , Keith F. McDaniel , Darold L. Madigan , Christopher E. Motter , John K. Pratt , Jason P. Shanley , Michael D. Tufano , Rolf Wagner , Rong Zhang , Akhteruzzaman Molla , Hongmei Mo , Tami J. Pilot-Matias , Sherie V L. Masse , Robert J. Carrick , Wenping He , Liangjun Lu , David J. Grampovnik
发明人: David A. Betebenner , David A. DeGoey , Clarence J. Maring , Allan C. Krueger , Nobuhiko Iwasaki , Todd W. Rockway , Curt S. Cooper , David D. Anderson , Pamela L. Donner , Brian E. Green , Dale J. Kempf , Dachun Liu , Keith F. McDaniel , Darold L. Madigan , Christopher E. Motter , John K. Pratt , Jason P. Shanley , Michael D. Tufano , Rolf Wagner , Rong Zhang , Akhteruzzaman Molla , Hongmei Mo , Tami J. Pilot-Matias , Sherie V L. Masse , Robert J. Carrick , Wenping He , Liangjun Lu , David J. Grampovnik
IPC分类号: C07D471/04 , A61P1/16
CPC分类号: C07D487/04 , C07D471/04 , C07D475/06 , C07D495/04 , C07D513/04
摘要: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
-
公开(公告)号:US20100256139A1
公开(公告)日:2010-10-07
申请号:US12817808
申请日:2010-06-17
申请人: Todd W. Rockway , David A. Betebenner , Allan C. Krueger , Nobuhiko Iwasaki , Curt S. Cooper , David D. Anderson , Dale J. Kempf , Darold L. Madigan , Christopher E. Motter , Jason P. Shanley , Michael D. Tufano , Rolf Wagner , Rong Zhang , Akhteruzzaman Molla , Hongmei Mo , Tami J. Pilot-Matias , Sherie V.L. Masse , Robert J. Carrick , Wenping He , Liangjun Lu
发明人: Todd W. Rockway , David A. Betebenner , Allan C. Krueger , Nobuhiko Iwasaki , Curt S. Cooper , David D. Anderson , Dale J. Kempf , Darold L. Madigan , Christopher E. Motter , Jason P. Shanley , Michael D. Tufano , Rolf Wagner , Rong Zhang , Akhteruzzaman Molla , Hongmei Mo , Tami J. Pilot-Matias , Sherie V.L. Masse , Robert J. Carrick , Wenping He , Liangjun Lu
IPC分类号: A61K31/5377 , C07D471/04 , A61K31/444 , A61P31/14
CPC分类号: C07D471/04
摘要: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
摘要翻译: 公开了有效抑制丙型肝炎病毒(“HCV”)或其他病毒复制的化合物。 本发明还涉及包含这些化合物的组合物,这些化合物与其它抗病毒剂或治疗剂的共同配制或共同给药,用于合成这些化合物的方法和中间体,以及使用这些化合物治疗 HCV或其他病毒感染。
-
公开(公告)号:US08338605B2
公开(公告)日:2012-12-25
申请号:US12817808
申请日:2010-06-17
申请人: Todd W. Rockway , David A. Betebenner , Allan C. Krueger , Nobuhiko Iwasaki , Curt S. Cooper , David D. Anderson , Dale J. Kempf , Darold L. Madigan , Christopher E. Motter , Jason P. Shanley , Michael D. Tufano , Rolf Wagner , Rong Zhang , Akteruzzaman Molla , Hongmei Mo , Tami J. Pilot-Matias , Sherie V. L. Masse , Robert J. Carrick , Wenping He , Liangjun Lu
发明人: Todd W. Rockway , David A. Betebenner , Allan C. Krueger , Nobuhiko Iwasaki , Curt S. Cooper , David D. Anderson , Dale J. Kempf , Darold L. Madigan , Christopher E. Motter , Jason P. Shanley , Michael D. Tufano , Rolf Wagner , Rong Zhang , Akteruzzaman Molla , Hongmei Mo , Tami J. Pilot-Matias , Sherie V. L. Masse , Robert J. Carrick , Wenping He , Liangjun Lu
IPC分类号: C07D471/02
CPC分类号: C07D471/04
摘要: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
摘要翻译: 公开了有效抑制丙型肝炎病毒(HCV)或其他病毒复制的化合物。 本发明还涉及包含这些化合物的组合物,这些化合物与其它抗病毒剂或治疗剂的共同配制或共同给药,用于合成这些化合物的方法和中间体,以及使用这些化合物治疗 HCV或其他病毒感染。
-
公开(公告)号:US08497275B2
公开(公告)日:2013-07-30
申请号:US12492518
申请日:2009-06-26
申请人: Brian E. Green , David D. Anderson , Todd D. Bosse , Curt S. Cooper , Larry L. Klein , Allan C. Krueger , Daniel P. Larson , Dachun Liu , Keith F. McDaniel , Christopher E. Motter , John K. Pratt , Todd W. Rockway , Teresa A. Rosenberg , Ming C. Yeung , Hui-Ju Chen , Jason P. Shanley
发明人: Brian E. Green , David D. Anderson , Todd D. Bosse , Curt S. Cooper , Larry L. Klein , Allan C. Krueger , Daniel P. Larson , Dachun Liu , Keith F. McDaniel , Christopher E. Motter , John K. Pratt , Todd W. Rockway , Teresa A. Rosenberg , Ming C. Yeung , Hui-Ju Chen , Jason P. Shanley
IPC分类号: A61K31/4965 , A61K31/40 , A61K38/00 , A61K38/05
CPC分类号: C07D403/12 , C07D207/16 , C07D241/24 , C07D403/14 , C07D409/14 , C07K7/02
摘要: This invention relates to: (a) compounds of formula I and salts thereof that, inter alia, are useful as hepatitis C virus (HCV) inhibitors; (b) intermediates useful for the preparation of such compounds and salts; (c) pharmaceutical compositions comprising such compounds and salts; and (d) methods of use of such compounds, salts, and compositions.
摘要翻译: 本发明涉及:(a)式I化合物及其盐,其特别可用作丙型肝炎病毒(HCV)抑制剂; (b)可用于制备这些化合物和盐的中间体; (c)包含这些化合物和盐的药物组合物; 和(d)使用这些化合物,盐和组合物的方法。
-
公开(公告)号:US20100029686A1
公开(公告)日:2010-02-04
申请号:US12492518
申请日:2009-06-26
申请人: Brian E. Green , David D. Anderson , Todd D. Bosse , Curt S. Cooper , Larry L. Klein , Allan C. Krueger , Daniel P. Larson , Dachun Liu , Keith F. McDaniel , Christopher E. Motter , John K. Pratt , Todd W. Rockway , Teresa A. Rosenberg , Ming C. Yeung , Hui-Ju Chen , Jason P. Shanley
发明人: Brian E. Green , David D. Anderson , Todd D. Bosse , Curt S. Cooper , Larry L. Klein , Allan C. Krueger , Daniel P. Larson , Dachun Liu , Keith F. McDaniel , Christopher E. Motter , John K. Pratt , Todd W. Rockway , Teresa A. Rosenberg , Ming C. Yeung , Hui-Ju Chen , Jason P. Shanley
IPC分类号: A61K31/497 , C07D241/12 , A61K31/4965 , C07D403/12 , C07D207/00 , A61K31/40 , A61P31/00
CPC分类号: C07D403/12 , C07D207/16 , C07D241/24 , C07D403/14 , C07D409/14 , C07K7/02
摘要: This invention relates to: (a) compounds of formula I and salts thereof that, inter alia, are useful as hepatitis C virus (HCV) inhibitors; (b) intermediates useful for the preparation of such compounds and salts; (c) pharmaceutical compositions comprising such compounds and salts; and (d) methods of use of such compounds, salts, and compositions.
摘要翻译: 本发明涉及:(a)式I化合物及其盐,其特别可用作丙型肝炎病毒(HCV)抑制剂; (b)可用于制备这些化合物和盐的中间体; (c)包含这些化合物和盐的药物组合物; 和(d)使用这些化合物,盐和组合物的方法。
-
公开(公告)号:US07737159B2
公开(公告)日:2010-06-15
申请号:US11675160
申请日:2007-02-15
申请人: David D. Anderson , Bruce A. Beutel , Curt S. Cooper , Yu-Gui Gu , Mira M. Hinman , Douglas M. Kalvin , Robert F. Keyes , Xenia B. Searle , Rolf Wagner
发明人: David D. Anderson , Bruce A. Beutel , Curt S. Cooper , Yu-Gui Gu , Mira M. Hinman , Douglas M. Kalvin , Robert F. Keyes , Xenia B. Searle , Rolf Wagner
IPC分类号: A61K31/44 , C07D515/02
CPC分类号: C07D513/04 , C07D207/12 , C07D207/16 , C07D239/48 , C07D277/36 , C07D471/04
摘要: Bacterial protein synthesis-inhibiting compounds having formula (I) and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates in the processes, compositions containing the compounds, and methods of using the compounds are disclosed.
摘要翻译: 公开了具有式(I)的具有式(I)的细菌蛋白质合成抑制化合物及其前体药物的前体药物,其制备方法,含该化合物的组合物,使用该化合物的方法。
-
-
-
-
-
-
-
-
-