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    Method to enhance aqueous solubility of poorly soluble actives
    1.
    发明授权
    Method to enhance aqueous solubility of poorly soluble actives 有权
    提高难溶性活性物质的水溶性的方法

    公开(公告)号：US08497303B2

    公开(公告)日：2013-07-30

    申请号：US12810962

    申请日：2009-01-05

    申请人： David B. Wurn ,  David A. Wilson ,  Bruce A. Barner ,  Cynthia L. Rand ,  Matthew D. Miller ,  Michael J. Johnson

    发明人： David B. Wurn ,  David A. Wilson ,  Bruce A. Barner ,  Cynthia L. Rand ,  Matthew D. Miller ,  Michael J. Johnson

    IPC分类号： A61K9/08 ,  A61K47/10 ,  A61K31/192 ,  A61K31/167

    CPC分类号： A61K31/167 ,  A61K9/08 ,  A61K31/192 ,  A61K47/10

    摘要： A method to enhance solubility of an active compound comprises combining an active compound, having an aqueous solubility that is less than or equal to about 10 mg/mL, and an amount of methoxypolyethylene glycol that is sufficient to increase the aqueous solubility of the active compound. Enhancement of aqueous solubility for this combination may be significantly greater than that of an active compound in combination with an equivalent amount of polyethylene glycol. Particularly enhanced solubility is shown where a small amount of water is also included. The invention may be used in a wide variety of applications, such as for pharmaceutical, agricultural, antimicrobial, and personal care products.

    摘要翻译： 提高活性化合物的溶解度的方法包括组合具有小于或等于约10mg / mL的水溶解度的活性化合物和足以提高活性化合物的水溶性的甲氧基聚乙二醇的量 。 该组合的水溶性的增强可以显着大于活性化合物与等量的聚乙二醇的组合。 显示特别增加的溶解度，其中也包括少量的水。 本发明可以用于各种各样的应用，例如用于制药，农业，抗微生物和个人护理产品。

    Cargo management system
    7.
    发明授权
    Cargo management system 有权
    货物管理系统

    公开(公告)号：US08528957B2

    公开(公告)日：2013-09-10

    申请号：US13172673

    申请日：2011-06-29

    申请人： Gian Carlo Morlet Ugalde ,  Babak Shahmehri ,  Kathleen Pecoraro ,  David A. Wilson ,  Marc Jonathon Lucas ,  Robert Joseph Beier ,  Timothy DeBastos

    发明人： Gian Carlo Morlet Ugalde ,  Babak Shahmehri ,  Kathleen Pecoraro ,  David A. Wilson ,  Marc Jonathon Lucas ,  Robert Joseph Beier ,  Timothy DeBastos

    IPC分类号： B62D43/06 ,  B62D21/00

    CPC分类号： B60R5/04 ,  B60K1/04 ,  B60R13/011

    摘要： A vehicle is provided with a seat oriented in a passenger compartment forward of a storage compartment. The seat has a seat back that is pivotally connected to a body of the vehicle. The seat back is pivotable between a seating position and a storage position. A battery is disposed within the storage compartment. A tray is removably connected to the vehicle body in either one of a first and a second position. The tray is elevated from the battery within the storage compartment in the first position. The tray is connected to the vehicle body such that it is contiguous with and forward of the battery in the second position. A flat load floor is formed by the top surface of a housing of the battery together with the tray.

    摘要翻译： 车辆设置有定位在储藏室前方的乘客室中的座椅。 座椅具有枢转地连接到车辆的车身的座椅靠背。 座椅靠背可在就座位置和存放位置之间枢转。 电池设置在储藏室内。 托盘在第一和第二位置中的任一个中可移除地连接到车身。 托盘在储物箱内的电池处于第一位置。 托盘连接到车体，使得其在第二位置与电池连续并向前。 平板负载地板由电池的壳体的顶面与托盘一起形成。

    REMINDER DEVICE
    8.
    发明申请
    REMINDER DEVICE 有权
    提醒装置

    公开(公告)号：US20090201773A1

    公开(公告)日：2009-08-13

    申请号：US12302181

    申请日：2007-05-25

    申请人： David A. Wilson ,  Gurjit S. Dhillon ,  Craig J. Tonge

    发明人： David A. Wilson ,  Gurjit S. Dhillon ,  Craig J. Tonge

    IPC分类号： G04F10/00

    CPC分类号： G04F1/005

    摘要： A single use reminder device (100) has a tamperproof housing which contains a counter circuit and a power supply. The device includes a status indicator (106) for indicating when a date or time period has elapsed. The device also includes a button (104) can be depressed so as to activate the status indicator (106). A traffic light LED system is operated, whereby a red signal is shown by the status indicator (106) if the date or time has elapsed, and whereby an amber signal is shown if the elapse date or time is imminent. A similar device comprises a laminated card structure having a portion, which can be pressed to provide status information via an LCD.

    摘要翻译： 一次使用提醒装置（100）具有包含计数器电路和电源的防篡改外壳。 该设备包括用于指示何时经过了日期或时间的状态指示器（106）。 该设备还包括可以按下按钮（104）以便激活状态指示器（106）。 操作交通灯LED系统，如果日期或时间已经过去，状态指示器（106）示出红色信号，并且如果经过逝去的日期或时间即将显示琥珀色信号。 类似的装置包括具有一部分的层压卡结构，其可被按压以经由LCD提供状态信息。

    Process for preparing dihydroxytrialkylammonium halides and products thereof
    9.
    发明授权
    Process for preparing dihydroxytrialkylammonium halides and products thereof 有权
    二羟基三烷基卤化铵的制备方法及其制备方法

    公开(公告)号：US07541496B2

    公开(公告)日：2009-06-02

    申请号：US11403779

    申请日：2006-04-13

    申请人： Joseph L. Deavenport ,  Rhonda C. Posey ,  David A. Wilson

    发明人： Joseph L. Deavenport ,  Rhonda C. Posey ,  David A. Wilson

    IPC分类号： C07C223/00 ,  C07C215/00 ,  C07C209/00

    CPC分类号： C07C215/40 ,  C07C213/02

    摘要： Compositions and methods for making compositions including a quaternary trialkylammonium halide compound are described. Compositions follow the formula: wherein the R1 groups are each individually selected from alkyl groups having from 1 to 12 carbon atoms; wherein the R2, R3, and R4 groups are each individually selected from hydrogen, hydroxide, alkyl groups having from 1 to 12 carbon atoms, and hydroxy alkyl groups having from 1 to 12 carbon atoms; wherein y ranges from 0 to 12; wherein X− is selected from fluoride, chloride, bromide, and iodide; wherein the quaternary trialkylammonium compound is present in an amount of at least 90 wt. percent; and wherein the composition comprises not greater than 4000 ppm of a trialkylamine or protonated form thereof.

    摘要翻译： 描述了制备包含四烷基三烷基卤化铵化合物的组合物的组合物和方法。 组合物遵循下式：其中R 1基团各自独立地选自具有1至12个碳原子的烷基; 其中R2，R3和R4各自独立地选自氢，氢氧根，具有1至12个碳原子的烷基和具有1至12个碳原子的羟基烷基; 其中y在0至12的范围内; 其中X-选自氟化物，氯化物，溴化物和碘化物; 其中季铵三烷基铵化合物的存在量为至少90wt。 百分; 并且其中所述组合物包含不大于4000ppm的三烷基胺或其质子化形式。

    FORMULATIONS WITH UNEXPECTED CLEANING PERFORMANCE INCORPORATING A BIODEGRADABLE CHELANT
    10.
    发明申请
    FORMULATIONS WITH UNEXPECTED CLEANING PERFORMANCE INCORPORATING A BIODEGRADABLE CHELANT 有权
    具有不可预见清洁性能的配方，包括可生物降解的连接器

    公开(公告)号：US20090099058A1

    公开(公告)日：2009-04-16

    申请号：US12297386

    申请日：2007-04-03

    申请人： Druce K. Crump ,  David A. Wilson

    发明人： Druce K. Crump ,  David A. Wilson

    IPC分类号： C11D3/33 ,  C09K3/00 ,  C11D1/62

    CPC分类号： C11D3/33 ,  C02F1/683 ,  C02F5/12 ,  C02F2101/20 ,  C02F2209/02 ,  C02F2305/04 ,  C11D3/046

    摘要： A chelating composition suitable for low-temperature use or storage is disclosed. The chelating compositions include 20 to 70 wt. percent of a polar solvent and 30 to 80 wt. percent of a first component of the formula: (I) wherein R is a hydroxyalkyl group and each R′ is individually selected from the group consisting of hydrogen, unsubstituted or inertly substituted alkyl groups, carbonyl-containing alkyl groups, carboxylate-containing alkyl groups, hydroxyalkyl groups and alkoxy groups; R″ is selected from the group consisting of hydrogen, unsubstituted or inertly substituted alkyl groups; carbonyl-substituted alkyl groups, carboxylate-containing alkyl groups, hydroxyalkyl groups and alkoxy groups; M1 and M2 are alkali metal ions, wherein the M1 has a higher atomic weight than M2; wherein x+y=n and the mole fraction of M1 is greater than 0.70 to 1. Methods of suppressing crystallization and methods of cleaning surfaces employing the compositions described herein are also disclosed.

    摘要翻译： 公开了适用于低温使用或储存的螯合组合物。 螯合组合物包含20至70wt。 极性溶剂的百分比和30至80wt。 百分数的下式的第一组分：（I）其中R是羟烷基，每个R'分别选自氢，未取代或惰性取代的烷基，含羰基的烷基，含羧酸的烷基 ，羟基烷基和烷氧基; R“选自氢，未取代或惰性取代的烷基; 羰基取代的烷基，含羧酸的烷基，羟基烷基和烷氧基; M1和M2是碱金属离子，其中M1具有比M2更高的原子量; 其中x + y = n，M1的摩尔分数大于0.70至1.还公开了使用本文所述的组合物抑制结晶的方法和清洁表面的方法。