METHODS OF TREATING IMPAIRED GLUCOSE METABOLISM VIA ADMINISTRATION OF ALGAL BIOMASS
    1.
    发明申请
    METHODS OF TREATING IMPAIRED GLUCOSE METABOLISM VIA ADMINISTRATION OF ALGAL BIOMASS 有权
    通过ALGAL生物量的管理处理受损葡萄糖代谢的方法

    公开(公告)号:US20120027724A1

    公开(公告)日:2012-02-02

    申请号:US13254035

    申请日:2010-03-03

    IPC分类号: A61K36/05 A61P3/08 A61P3/04

    摘要: The invention is directed to methods of using Chlorella protothecoides microalgal biomass in the treatment of individuals having impaired glucose metabolism. In some cases, the patient has impaired fasting glucose, impaired glucose tolerance, or diabetes. In some methods, algal biomass is used to reduce blood glucose and/or body fat in a subject, or to increase the relative abundance of beneficial gut microflora in a subject. In preferred embodiments, the biomass is derived from Chlorella protothecoides cultures grown heterotrophically in which the algal cells comprise at least 15% algal oil by dry weight.

    摘要翻译: 本发明涉及使用原小球藻微藻生物质处理葡萄糖代谢受损个体的方法。 在某些情况下,患者空腹血糖受损,糖耐量异常或糖尿病。 在一些方法中,藻类生物质用于降低受试者的血糖和/或体脂肪,或增加受试者中有益的肠道微生物群落的相对丰度。 在优选的实施方案中,生物质衍生自异养生长的球藻藻细胞培养物,其中藻类细胞含有至少15%的干重的藻油。

    Methods of treating impaired glucose metabolism via administration of algal biomass
    2.
    发明授权
    Methods of treating impaired glucose metabolism via administration of algal biomass 有权
    通过施用藻类生物量来治疗糖代谢紊乱的方法

    公开(公告)号:US08747834B2

    公开(公告)日:2014-06-10

    申请号:US13254035

    申请日:2010-03-03

    IPC分类号: A01N63/00 A01N65/00

    摘要: The invention is directed to methods of using Chlorella protothecoides microalgal biomass in the treatment of individuals having impaired glucose metabolism. In some cases, the patient has impaired fasting glucose, impaired glucose tolerance, or diabetes. In some methods, algal biomass is used to reduce blood glucose and/or body fat in a subject, or to increase the relative abundance of beneficial gut microflora in a subject. In preferred embodiments, the biomass is derived from Chlorella protothecoides cultures grown heterotrophically in which the algal cells comprise at least 15% algal oil by dry weight.

    摘要翻译: 本发明涉及使用原小球藻微藻生物质处理葡萄糖代谢受损个体的方法。 在某些情况下,患者空腹血糖受损,糖耐量异常或糖尿病。 在一些方法中,藻类生物质用于降低受试者的血糖和/或体脂肪,或增加受试者中有益的肠道微生物群落的相对丰度。 在优选的实施方案中,生物质衍生自异养生长的球藻藻细胞培养物,其中藻类细胞含有至少15%的干重的藻油。

    Soaps Produced from Oil-Bearing Microbial Biomass and Oils
    9.
    发明申请
    Soaps Produced from Oil-Bearing Microbial Biomass and Oils 有权
    由含油微生物油和油生产的肥皂

    公开(公告)号:US20090305942A1

    公开(公告)日:2009-12-10

    申请号:US12499033

    申请日:2009-07-07

    IPC分类号: C11D17/08 C12P7/64

    摘要: Soap and cosmetic products can be made from oil-bearing microbial biomass via the alkaline hydrolysis of glycerolipids and fatty acid esters to fatty acid salts. The saponified microbial oils/lipids can be combined with a variety of additives to produce compositions for use as soaps and other cosmetic products, which may also contain other constituents of the biomass, including unsaponified oils, glycerol and carotenoids, among others.

    摘要翻译: 肥皂和化妆品可以由含油微生物生物质通过甘油脂肪和脂肪酸酯的碱水解生成脂肪酸盐。 皂化的微生物油/脂质可以与各种添加剂组合以产生用作肥皂和其它化妆品的组合物,其也可以含有生物质的其它成分,包括非皂化油,甘油和类胡萝卜素等。

    Peptides and supported peptides for treating skin diseases
    10.
    发明授权
    Peptides and supported peptides for treating skin diseases 有权
    用于治疗皮肤疾病的肽和支持的肽

    公开(公告)号:US07524816B2

    公开(公告)日:2009-04-28

    申请号:US10984270

    申请日:2004-11-08

    IPC分类号: A61K38/16

    摘要: The present invention provides peptides and supported peptides for treating proliferative diseases. In particularly preferred embodiments, the present invention provides peptides and supported peptides for treating diseases of the skin, such as rosacea. In some particularly preferred embodiments, the supported peptides of the present invention are anti-VEGF peptides. In alternative particularly preferred embodiments, the anti-VEGF peptides are expressed on a scaffold protein. In some most preferred embodiments, the scaffold proteins is BBI.

    摘要翻译: 本发明提供用于治疗增殖性疾病的肽和负载肽。 在特别优选的实施方案中,本发明提供用于治疗皮肤疾病的肽和负载肽,例如红斑痤疮。 在一些特别优选的实施方案中,本发明的负载型肽是抗VEGF肽。 在替代的特别优选的实施方案中,抗VEGF肽在支架蛋白上表达。 在一些最优选的实施方案中,支架蛋白是BBI。