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1.发明授权公开(公告)号：US07297261B2
公开(公告)日：2007-11-20
申请号：US11700626
申请日：2007-01-31
申请人： David C. Bomberger , Bryan Chavez , Pablo E. Garcia , Eric Hegwer , Thomas P. Low , Ripudaman Malhotra , Jeffrey J. Shimon
发明人： David C. Bomberger , Bryan Chavez , Pablo E. Garcia , Eric Hegwer , Thomas P. Low , Ripudaman Malhotra , Jeffrey J. Shimon
CPC分类号： B01D63/02 , A61M1/34 , A61M1/3403 , A61M1/3472 , A61M1/3482 , A61M1/3486 , A61M1/3496 , A61M2202/0456 , A61M2202/08 , A61M2202/203 , A61M2202/206 , A61M2205/3306 , A61M2205/3368 , B01D11/0415 , B01D11/0457 , B01D11/0488 , B01D11/0492 , B01D61/246 , B01D61/36 , B01D2317/02 , B01F5/0646 , B01F5/0647 , B01F5/10 , B01F7/1635 , B01F9/02 , B01F11/0014 , B01F11/0283 , B01F2009/0063
摘要： Systems and methods for removing lipids from a fluid, such as plasma, or from lipid-containing organisms. A fluid is combined with at least one extraction solvent, which causes the lipids to separate from the fluid or from lipid-containing organisms. The separated lipids are removed from the fluid. The extraction solvent is removed from the fluid or at least reduced to an acceptable concentration enabling the delipidated fluid to be administered to a patient without the patient experiencing undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid, to a different patient, or stored for later use.
摘要翻译： 用于从流体（例如血浆）或从含脂质生物体中除去脂质的系统和方法。 流体与至少一种提取溶剂组合，其引起脂质与流体或含脂质生物分离。 将分离的脂质从流体中除去。 将萃取溶剂从流体中除去或至少降低到可接受的浓度，使得能够将脱脂流体施用于患者，而不会使患者经历不期望的后果。 一旦流体被处理，流体可以被给予捐赠流体的患者给不同的患者，或者存储以供以后使用。
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2.发明授权Systems and methods using multiple solvents for the removal of lipids from fluids 失效使用多种溶剂从流体中除去脂质的系统和方法公开(公告)号：US07402246B2
公开(公告)日：2008-07-22
申请号：US11769872
申请日：2007-06-28
申请人： David C. Bomberger , Bryan Chavez , Pablo E. Garcia , Eric Hegwer , Thomas P. Low , Ripudaman Malhotra , Jeffrey J. Shimon
发明人： David C. Bomberger , Bryan Chavez , Pablo E. Garcia , Eric Hegwer , Thomas P. Low , Ripudaman Malhotra , Jeffrey J. Shimon
CPC分类号： B01D61/362 , A61M1/34 , A61M1/3403 , A61M1/341 , A61M1/342 , A61M1/3468 , A61M1/3472 , A61M1/3482 , A61M1/3486 , A61M1/3496 , A61M1/3693 , A61M2202/0456 , A61M2202/08 , A61M2202/203 , A61M2202/206 , A61M2205/3368 , B01D11/043 , B01D11/0492 , B01D61/246 , B01D63/02 , B01D63/046 , B01D2313/50
摘要： This invention is directed to systems and methods for removing lipids from a fluid or from lipid-containing organisms from a fluid, such as plasma. These systems combine a fluid with at least one extraction solvent, which causes the lipids to separate from the fluid or from the lipid-containing organisms. The separated lipids are removed from the fluid. The at least one extraction solvent is removed from the fluid or at least reduced to a concentration enabling the fluid to be administered to a patient without undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid or to a different patient for therapy.
摘要翻译： 本发明涉及从流体或诸如血浆的流体中从含脂质生物体中除去脂质的系统和方法。 这些系统将流体与至少一种提取溶剂组合，其引起脂质与流体或含脂质生物分离。 将分离的脂质从流体中除去。 将至少一种提取溶剂从流体中除去或者至少减少到使得能够向患者施用流体的浓度，而不会产生不期望的后果。 一旦流体被处理，流体可以被施用给捐赠流体的患者或不同的患者进行治疗。
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3.发明授权Systems and methods using multiple solvents for removal of lipids from fluids 失效使用多种溶剂从流体中除去脂质的系统和方法公开(公告)号：US07364658B2
公开(公告)日：2008-04-29
申请号：US11737939
申请日：2007-04-20
申请人： David C. Bomberger , Bryan Chavez , Pablo E. Garcia , Eric Hegwer , Thomas P. Low , Ripudaman Malhotra , Jeffrey J. Shimon
发明人： David C. Bomberger , Bryan Chavez , Pablo E. Garcia , Eric Hegwer , Thomas P. Low , Ripudaman Malhotra , Jeffrey J. Shimon
CPC分类号： B01D61/362 , A61M1/34 , A61M1/3403 , A61M1/342 , A61M1/3472 , A61M1/3482 , A61M1/3486 , A61M1/3496 , A61M1/3693 , A61M2202/0456 , A61M2202/08 , A61M2202/203 , A61M2202/206 , A61M2205/3306 , A61M2205/3331 , A61M2205/3334
摘要： This invention is directed to systems and methods for removing lipids from a fluid or from lipid-containing organisms from a fluid, such as plasma. These systems combine a fluid with at least one extraction solvent, which causes the lipids to separate from the fluid or from the lipid-containing organisms. The separated lipids are removed from the fluid. The at least one extraction solvent is removed from the fluid or at least reduced to a concentration enabling the fluid to be administered to a patient without undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid or to a different patient for therapy.
摘要翻译： 本发明涉及从流体或诸如血浆的流体中从含脂质生物体中除去脂质的系统和方法。 这些系统将流体与至少一种提取溶剂组合，其引起脂质与流体或含脂质生物分离。 将分离的脂质从流体中除去。 将至少一种提取溶剂从流体中除去或者至少减少到使得能够向患者施用流体的浓度，而不会产生不期望的后果。 一旦流体被处理，流体可以被施用给捐赠流体的患者或不同的患者进行治疗。
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4.发明授权Systems and methods using multiple solvents for the removal of lipids from fluids 失效使用多种溶剂从流体中除去脂质的系统和方法公开(公告)号：US07195710B2
公开(公告)日：2007-03-27
申请号：US10856046
申请日：2004-05-28
申请人： David C. Bomberger , Bryan Chavez , Pablo E. Garcia , Eric Hegwer , Thomas P. Low , Ripudaman Malhotra , Jeffrey J. Shimon
发明人： David C. Bomberger , Bryan Chavez , Pablo E. Garcia , Eric Hegwer , Thomas P. Low , Ripudaman Malhotra , Jeffrey J. Shimon
CPC分类号： B01D61/362 , A61M1/34 , A61M1/3403 , A61M1/342 , A61M1/3472 , A61M1/3482 , A61M1/3486 , A61M1/3496 , A61M1/3693 , A61M2202/0456 , A61M2202/08 , A61M2202/203 , A61M2202/206 , A61M2205/3306 , A61M2205/3331 , A61M2205/3334
摘要： This invention is directed to systems and methods for removing lipids from a fluid or from lipid-containing organisms from a fluid, such as plasma. These systems combine a fluid with at least one extraction solvent, which causes the lipids to separate from the fluid or from the lipid-containing organisms. The separated lipids are removed from the fluid. The at least one extraction solvent is removed from the fluid or at least reduced to a concentration enabling the fluid to be administered to a patient without undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid or to a different patient for therapy.
摘要翻译： 本发明涉及从流体或诸如血浆的流体中从含脂质生物体中除去脂质的系统和方法。 这些系统将流体与至少一种提取溶剂组合，其引起脂质与流体或含脂质生物分离。 将分离的脂质从流体中除去。 将至少一种提取溶剂从流体中除去或者至少减少到使得能够向患者施用流体的浓度，而不会产生不期望的后果。 一旦流体被处理，流体可以被施用给捐赠流体的患者或不同的患者进行治疗。
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5.发明申请Systems and Methods Using Multiple Solvents for the Removal of Lipids from Fluids 审中-公开使用多种溶剂从流体中去除脂质的系统和方法公开(公告)号：US20080203022A1
公开(公告)日：2008-08-28
申请号：US12114851
申请日：2008-05-05
申请人： David C. Bomberger , Bryan Chavez , Pablo E. Garcia , Eric Hegwer , Thomas P. Low , Ripudaman Malhotra , Jeffrey J. Shimon
发明人： David C. Bomberger , Bryan Chavez , Pablo E. Garcia , Eric Hegwer , Thomas P. Low , Ripudaman Malhotra , Jeffrey J. Shimon
IPC分类号： B01D61/58
CPC分类号： B01D61/362 , A61M1/34 , A61M1/3403 , A61M1/341 , A61M1/342 , A61M1/3468 , A61M1/3472 , A61M1/3482 , A61M1/3486 , A61M1/3496 , A61M1/3693 , A61M2202/0456 , A61M2202/08 , A61M2202/203 , A61M2202/206 , A61M2205/3368 , B01D11/043 , B01D11/0492 , B01D61/246 , B01D63/02 , B01D63/046 , B01D2313/50
摘要： This invention is directed to systems and methods for removing lipids from a fluid or from lipid-containing organisms from a fluid, such as plasma. These systems combine a fluid with at least one extraction solvent, which causes the lipids to separate from the fluid or from the lipid-containing organisms. The separated lipids are removed from the fluid. The at least one extraction solvent is removed from the fluid or at least reduced to a concentration enabling the fluid to be administered to a patient without undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid or to a different patient for therapy.
摘要翻译： 本发明涉及从流体或诸如血浆的流体中从含脂质生物体中除去脂质的系统和方法。 这些系统将流体与至少一种提取溶剂组合，其引起脂质与流体或含脂质生物分离。 将分离的脂质从流体中除去。 将至少一种提取溶剂从流体中除去或者至少减少到使得能够向患者施用流体的浓度，而不会产生不期望的后果。 一旦流体被处理，流体可以被施用给捐赠流体的患者或不同的患者进行治疗。
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公开(公告)号：US20080149572A1
公开(公告)日：2008-06-26
申请号：US12039831
申请日：2008-02-29
申请人： David C. Bomberger , Bryan Chavez , Pablo E. Garcia , Eric Hegwer , Thomas P. Low , Ripudaman Malhotra , Jeffrey J. Shimon
发明人： David C. Bomberger , Bryan Chavez , Pablo E. Garcia , Eric Hegwer , Thomas P. Low , Ripudaman Malhotra , Jeffrey J. Shimon
IPC分类号： B01D21/26
CPC分类号： B01D61/362 , A61M1/34 , A61M1/3403 , A61M1/341 , A61M1/342 , A61M1/3468 , A61M1/3472 , A61M1/3482 , A61M1/3486 , A61M1/3496 , A61M1/3693 , A61M2202/0456 , A61M2202/08 , A61M2202/203 , A61M2202/206 , A61M2205/3368 , B01D11/043 , B01D11/0492 , B01D61/246 , B01D63/02 , B01D63/046 , B01D2313/50
摘要： This invention is directed to systems and methods for removing lipids from a fluid or from lipid-containing organisms from a fluid, such as plasma. These systems combine a fluid with at least one extraction solvent, which causes the lipids to separate from the fluid or from the lipid-containing organisms. The separated lipids are removed from the fluid. The at least one extraction solvent is removed from the fluid or at least reduced to a concentration enabling the fluid to be administered to a patient without undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid or to a different patient for therapy.
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公开(公告)号：US07033500B2
公开(公告)日：2006-04-25
申请号：US10178900
申请日：2002-06-21
申请人： David C. Bomberger , Bryan Chavez , Pablo E. Garcia , Eric Hegwer , Thomas P. Low , Ripudaman Malhotra , Jeffrey J. Shimon
发明人： David C. Bomberger , Bryan Chavez , Pablo E. Garcia , Eric Hegwer , Thomas P. Low , Ripudaman Malhotra , Jeffrey J. Shimon
CPC分类号： B01D61/362 , A61M1/34 , A61M1/3403 , A61M1/342 , A61M1/3472 , A61M1/3482 , A61M1/3486 , A61M1/3496 , A61M1/3693 , A61M2202/0456 , A61M2202/08 , A61M2202/203 , A61M2202/206 , A61M2205/3306 , A61M2205/3331 , A61M2205/3334
摘要： This invention is directed to systems and methods for removing lipids from a fluid or from lipid-containing organisms from a fluid, such as plasma. These systems combine a fluid with at least one extraction solvent, which causes the lipids to separate from the fluid or from the lipid-containing organisms. The separated lipids are removed from the fluid. The at least one extraction solvent is removed from the fluid or at least reduced to a concentration enabling the fluid to be administered to a patient without undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid or to a different patient for therapy.
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公开(公告)号：US07166223B2
公开(公告)日：2007-01-23
申请号：US11221617
申请日：2005-09-08
CPC分类号： B01D61/362 , A61M1/34 , A61M1/3403 , A61M1/341 , A61M1/342 , A61M1/3468 , A61M1/3472 , A61M1/3482 , A61M1/3486 , A61M1/3496 , A61M1/3693 , A61M2202/0456 , A61M2202/08 , A61M2202/203 , A61M2202/206 , A61M2205/3368 , B01D11/043 , B01D11/0492 , B01D61/246 , B01D63/02 , B01D63/046 , B01D2313/50
摘要： This invention is directed to systems and methods for removing lipids from a fluid, such as plasma, or from lipid-containing organisms. These systems contact a fluid with an extraction solvent, which causes the lipids in the fluid to separate from the fluid or causes lipids in the lipid-containing organisms to separate from the lipid-containing organism, using at least one hollow fiber contactor. The separated lipids are removed from the fluid. The extraction solvent is removed from the fluid or at least reduced to a level below a particular threshold enabling the fluid to be administered to a patient without the patient experiencing undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid, to a different patient, or be stored.
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公开(公告)号：US20090032468A1
公开(公告)日：2009-02-05
申请号：US11868551
申请日：2007-10-08
IPC分类号： B01D11/04
CPC分类号： B01D61/362 , A61M1/34 , A61M1/3403 , A61M1/341 , A61M1/342 , A61M1/3468 , A61M1/3472 , A61M1/3482 , A61M1/3486 , A61M1/3496 , A61M1/3693 , A61M2202/0456 , A61M2202/08 , A61M2202/203 , A61M2202/206 , A61M2205/3368 , B01D11/043 , B01D11/0492 , B01D61/246 , B01D63/02 , B01D63/046 , B01D2313/50
摘要： This invention is directed to systems and methods for removing lipids from a fluid, such as plasma, or from lipid-containing organisms. These systems contact a fluid with an extraction solvent, which causes the lipids in the fluid to separate from the fluid or causes lipids in the lipid-containing organisms to separate from the lipid-containing organism, using at least one hollow fiber contactor. The separated lipids are removed from the fluid. The extraction solvent is removed from the fluid or at least reduced to a level below a particular threshold enabling the fluid to be administered to a patient without the patient experiencing undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid, to a different patient, or be stored.
摘要翻译： 本发明涉及从流体（例如血浆）或从含脂质生物体中除去脂质的系统和方法。 这些系统与提取溶剂接触流体，其使得流体中的脂质与流体分离，或者使用至少一个中空纤维接触器使含脂质生物体中的脂质与含脂质生物体分离。 将分离的脂质从流体中除去。 将萃取溶剂从流体中除去或至少降低到低于特定阈值的水平，使得能够将流体施用于患者，而患者不经历不期望的后果。 一旦液体已经被处理，流体可以被给予捐赠流体的患者，给不同的患者或被储存。
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公开(公告)号：US07297262B2
公开(公告)日：2007-11-20
申请号：US11589376
申请日：2006-10-30
CPC分类号： B01D61/362 , A61M1/34 , A61M1/3403 , A61M1/341 , A61M1/342 , A61M1/3468 , A61M1/3472 , A61M1/3482 , A61M1/3486 , A61M1/3496 , A61M1/3693 , A61M2202/0456 , A61M2202/08 , A61M2202/203 , A61M2202/206 , A61M2205/3368 , B01D11/043 , B01D11/0492 , B01D61/246 , B01D63/02 , B01D63/046 , B01D2313/50
摘要： This invention is directed to systems and methods for removing lipids from a fluid, such as plasma, or from lipid-containing organisms. These systems contact a fluid with an extraction solvent, which causes the lipids in the fluid to separate from the fluid or causes lipids in the lipid-containing organisms to separate from the lipid-containing organism, using at least one hollow fiber contactor. The separated lipids are removed from the fluid. The extraction solvent is removed from the fluid or at least reduced to a level below a particular threshold enabling the fluid to be administered to a patient without the patient experiencing undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid, to a different patient, or be stored.
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