STABILIZED OPHTHALMIC SOLUTIONS
    2.
    发明申请
    STABILIZED OPHTHALMIC SOLUTIONS 审中-公开
    稳定的眼科解决方案

    公开(公告)号:US20090004288A1

    公开(公告)日:2009-01-01

    申请号:US12124882

    申请日:2008-05-21

    IPC分类号: A61K33/40

    摘要: The present invention relates to stabilized ophthalmic solutions comprising at least one peroxide. In one embodiment, the present invention relates to an ophthalmic solution comprising a pH between about 6 and about 8 and about 50 to about 1000 ppm hydrogen peroxide and about 0.005 wt % (50 ppm) to about 0.05 wt % (500 ppm) at least one salt of diethylenetriamine pentaacetic acid selected from the group consisting of calcium salts of diethylenetriamine pentaacetic acid, zinc salts of diethylenetriamine pentaacetic acid and mixed calcium/zinc salts of diethylenetriamine pentaacetic acid.The present invention further relates to a method for preserving ophthalmic solution comprising at least one peroxide.

    摘要翻译: 本发明涉及包含至少一种过氧化物的稳定的眼用溶液。 在一个实施方案中,本发明涉及一种眼用溶液,其包含至少约6至约8至约10至约1000ppm过氧化氢和约0.005重量%(50ppm)至约0.05重量%(500ppm)的pH 二亚乙基三胺五乙酸的一种盐,选自二亚乙基三胺五乙酸钙盐,二亚乙基三胺五乙酸锌盐和二亚乙基三胺五乙酸的混合钙/锌盐。 本发明还涉及一种用于保存含有至少一种过氧化物的眼用溶液的方法。