公开(公告)号：US20210032083A1

公开(公告)日：2021-02-04

申请号：US16525368

申请日：2019-07-29

Applicant: David Fink

Inventor： David Fink

IPC: B66F9/14

Abstract: An extension system for a pallet lift and translate tool is provided including a right fork extension arm having a length, including a right angle bar attached to a right rear cover bracket. A mirrored left fork extension arm is also provided having a length, including at least a left angle bar attached to a left rear cover bracket. With the right rear bracket placed around a right fork of the pallet lift and translate tool, and the left rear bracket placed around a left fork of the pallet lift and translate tool, the right and left angle bars extend away from the body along the forks and the right and left extension arms may be extended past a length of the right and left forks to accommodate lifting pallets having different sizes in relation to lengths of the right and left forks.

公开(公告)号：US20080273858A1

公开(公告)日：2008-11-06

申请号：US11990356

申请日：2006-06-29

Applicant: Stephanie Wald ,  Ezra Darshan ,  David Fink ,  Kevin Murray

Inventor： Stephanie Wald ,  Ezra Darshan ,  David Fink ,  Kevin Murray

IPC: H04N5/91

CPC classification number: G11B27/031 ,  H04N5/76 ,  H04N5/783 ,  H04N5/85 ,  H04N9/8042 ,  H04N9/8205

Abstract: A method for producing an auxiliary video stream arranged for reverse trick mode playback from a video stream including a plurality of uni-directional predicted frames, the method including producing the auxiliary video stream by performing the following steps copying each uni-directional predicted frame included in the video stream into a memory, thereby producing a plurality of copied frames in the memory, replacing each one of the plurality of copied frames with one corresponding supplemental frame, thereby producing a plurality of corresponding supplemental frames, and producing a copy of the video stream arranged in reverse processing order, the producing a copy including replacing each frame which corresponds to one of the plurality of copied frames with the one corresponding supplemental frame from among the plurality of corresponding supplemental frames. Related methods and systems are also described.

Abstract translation: 一种用于产生由包括多个单向预测帧的视频流反向特技模式重放的辅助视频流的制造方法，该方法包括：通过执行以下步骤来产生辅助视频流：复制包括在每个单向预测帧中的每个单向预测帧 视频流进入存储器，从而在存储器中产生多个复制的帧，用一个对应的补充帧替换多个复制帧中的每一个，从而产生多个对应的补充帧，并产生视频流的副本 以反向处理顺序排列，产生一个副本，包括从多个对应的补充帧中用一个对应的补充帧替换对应于多个复制帧之一的每个帧。 还描述了相关方法和系统。

公开(公告)号：US20080044161A1

公开(公告)日：2008-02-21

申请号：US11628402

申请日：2005-06-08

Applicant: David White ,  Kevin Murray ,  Ezra Darshan ,  Moshe Shlissel ,  David Fink ,  David Whittaker ,  Zeev Geyzel ,  Reuven Wachtfogel

Inventor： David White ,  Kevin Murray ,  Ezra Darshan ,  Moshe Shlissel ,  David Fink ,  David Whittaker ,  Zeev Geyzel ,  Reuven Wachtfogel

IPC: H04N5/91

CPC classification number: G11B27/105 ,  G11B27/322 ,  H04N21/4325 ,  H04N21/44016

Abstract: A method for switching from playing a first compressed data segment to playing a second compressed recorded data segment, the method including playing an uncompressed copy of a start of the second compressed recorded data segment upon switching from playing the first compressed data segment, decoding the second compressed recorded data segment from a preceding random access point, the preceding random access point preceding, in the second compressed recorded data segment, a point at which playing is to be switched to the second compressed recorded data segment, stopping the decoding of the second compressed recorded data segment when reaching a point beyond a point currently being played in the uncompressed copy, and switching to playing the second compressed recorded data segment when playing the uncompressed copy of a start of the second compressed recorded data segment reaches the point at which the decoding of the second compressed recorded data segment was stopped. Related apparatus and methods are also provided.

Abstract translation: 一种用于从播放第一压缩数据段切换到播放第二压缩记录数据段的方法，所述方法包括：从播放所述第一压缩数据段切换时播放所述第二压缩记录数据段的开始的未压缩副本， 从前一个随机接入点的前一随机接入点的压缩记录数据段，在第二压缩记录数据段中的前一个随机接入点，播放要切换到第二压缩记录数据段的点，停止对第二压缩记录数据段的解码 当到达超过当前在未压缩副本中播放的点的点时记录数据段，并且当播放第二压缩记录数据段的开始的未压缩副本时切换到播放第二压缩记录数据段到达解码的点 的第二压缩记录数据段被停止。 还提供了相关的装置和方法。

公开(公告)号：US20070066946A1

公开(公告)日：2007-03-22

申请号：US11516925

申请日：2006-09-06

Applicant: Kurt Haggstrom ,  David Fink ,  Katja Grundmeier

Inventor： Kurt Haggstrom ,  David Fink ,  Katja Grundmeier

IPC: A61M1/00

CPC classification number: A61M1/0027 ,  A61F13/00063 ,  A61F13/00068 ,  A61F13/0209 ,  A61F13/0216 ,  A61M1/0031 ,  A61M1/0088 ,  A61M27/00 ,  A61M39/24 ,  A61M2205/15 ,  A61M2205/18 ,  A61M2205/3344 ,  A61M2205/3368 ,  A61M2205/583 ,  A61M2205/584 ,  A61M2205/587 ,  A61M2205/6081 ,  A61M2205/8206

Abstract: A wound dressing apparatus includes a wound dressing member dimensioned for positioning relative to a wound bed. The wound dressing member including an internal vacuum reservoir and has a port in communication with the vacuum reservoir for applying subatmospheric pressure to the vacuum reservoir to facilitate removal of fluid from the wound bed. The wound dressing member includes a visual pressure indicator associated therewith for indicating a level of pressure within the vacuum reservoir. The visual pressure indicator includes color indicia having a plurality of colors corresponding to a condition of the pressure within the vacuum reservoir. The wound dressing member includes a lower absorbent member positionable adjacent the wound bed and an upper member which at least partially defines the vacuum reservoir. At least one of the top member and the lower absorbent member has the visual pressure indicator mounted thereto. The preferred visual pressure indicator includes an electronic position sensor. The visual pressure indicator further includes circuit means and visible alarm means. The circuit means is adapted to actuate the visible alarm means when the position sensor detects a relative positioning of the top member of the wound dressing member to provide a visual indication of the condition of the subatmospheric pressure within the vacuum reservoir.

Abstract translation: 一种伤口敷料装置包括用于相对于伤口床定位的伤口敷料构件。 所述伤口敷料构件包括内部真空容器，并且具有与所述真空容器连通的端口，用于向所述真空容器施加低于大气压的压力，以便于从所述伤口床移除流体。 伤口敷料构件包括与其相关联的视觉压力指示器，用于指示真空容器内的压力水平。 视觉压力指示器包括具有对应于真空容器内的压力状态的多种颜色的颜色标记。 所述伤口敷料构件包括可邻近所述伤口床定位的下部吸收体，以及至少部分限定所述真空容器的上部构件。 顶部构件和下部吸收构件中的至少一个具有安装在其上的视觉压力指示器。 优选的视觉压力指示器包括电子位置传感器。 视觉压力指示器还包括电路装置和可见报警装置。 当位置传感器检测到伤口敷料构件的顶部构件的相对定位以提供在真空容器内的低于大气压的状况的视觉指示时，电路装置适于致动可见警报装置。

公开(公告)号：US20070004695A1

公开(公告)日：2007-01-04

申请号：US11459068

申请日：2006-07-21

Applicant: David Fink ,  Brian Freed ,  Nicholas Hrib ,  Raymond Kosley ,  George Lee ,  Gregory Merriman ,  Barbara Rauckman

Inventor： David Fink ,  Brian Freed ,  Nicholas Hrib ,  Raymond Kosley ,  George Lee ,  Gregory Merriman ,  Barbara Rauckman

IPC: A61K31/5377 ,  A61K31/496 ,  C07D471/00 ,  A61K31/4745 ,  A61K31/4743 ,  A61K31/454 ,  A61K31/4709 ,  A61K31/42 ,  A61K31/4162

CPC classification number: C07D495/04

Abstract: The compounds are of the class thienoisoxazolyl- and thienylpyrrazolyl-phenoxy substituted propyl derivatives, useful as D4 antagonists. Said compounds are useful for the treatment of medical conditions mediated by inhibition of D4 receptor. These conditions comprise, for example, Attention Deficit Hyperactivity Disorder, Obsessive-Compulsive Disorder, Psychoses, Substance Abuse, Substance Dependence, Parkinson's Disease, Parkinsonism, Tardive Diskinesia, Gilles de la Tourette Syndrome, Conduct Disorder, and Oppositional Defiant Disorder. A further aspect of the invention is to provide a pharmaceutical composition, intermediates, and a method of making said class of compounds.

Abstract translation: 这些化合物是类似噻吩并恶唑基和噻吩基吡唑基 - 苯氧基取代的丙基衍生物，可用作D 4 N 4拮抗剂。 所述化合物可用于治疗通过抑制D 4受体介导的医学病症。 这些病症包括例如注意力缺陷多动障碍，强迫症，精神病，药物滥用，物质依赖性，帕金森病，帕金森综合征，迟发性麻痹症，杜氏综合征，行为障碍和反对性反抗障碍。 本发明的另一方面是提供药物组合物，中间体和制备所述类化合物的方法。

公开(公告)号：US20050147959A1

公开(公告)日：2005-07-07

申请号：US10508497

申请日：2003-03-21

Applicant: Carmelita Frondoza ,  David Fink

Inventor： Carmelita Frondoza ,  David Fink

IPC: A01N1/02 ,  C12N5/071 ,  C12N5/077 ,  C12Q1/00 ,  G01N33/50 ,  C12N5/08

CPC classification number: C12N5/0697 ,  C12N5/0655 ,  C12N2501/23 ,  C12N2501/25 ,  C12N2503/04 ,  C12N2531/00 ,  G01N33/5082

Abstract: A test system and method are disclosed for using tissue analogs The method includes the following steps: (1) isolating the cells to be implanted from donor tissue; (2) seeding the cells onto a particulate microcarrier bead; (3) culturing the cells on the microcarriers to achieve an expansion in the number of cells; and (4) further culturing the cell-particle aggregates to form a tissue analog. The resulting tissue analog and test system may be used for use in screening drugs for diseases and pathological conditions, for testing for toxicity of chemical agents, or for genomic or proteomic screening. The tissue analogs may also be subjected to conditions that will induce disease-like conditions such that the resulting diseased tissue analogs may be used to screen for therapeutic drugs that modify the diseased tissue analog physiology or block progression of the diseased conditions. Kits may be developed for the purpose of conducting multiple tests in conventional multi-well plate systems.

Abstract translation: 公开了使用组织类似物的测试系统和方法。该方法包括以下步骤：（1）从供体组织中分离待植入的细胞; （2）将细胞接种在微粒载体珠粒上; （3）在微载体上培养细胞以实现细胞数量的扩大; 和（4）进一步培养细胞 - 颗粒聚集体以形成组织类似物。 所得到的组织类似物和测试系统可用于筛选用于疾病和病理状况的药物，用于测试化学试剂的毒性，或用于基因组或蛋白质组学筛选。 组织类似物还可以经受将引起疾病状况的病症，使得所得到的患病组织类似物可用于筛选改变患病组织的类似生理学或阻断疾病状态进展的治疗药物。 可以开发套件，用于在常规多孔板系统中进行多次测试。

公开(公告)号：US08787737B2

公开(公告)日：2014-07-22

申请号：US11990356

申请日：2006-06-29

Applicant: Stephanie Wald ,  Ezra Darshan ,  David Fink ,  Kevin Murray

Inventor： Stephanie Wald ,  Ezra Darshan ,  David Fink ,  Kevin Murray

IPC: H04N5/783

CPC classification number: G11B27/031 ,  H04N5/76 ,  H04N5/783 ,  H04N5/85 ,  H04N9/8042 ,  H04N9/8205

Abstract: A method for producing an auxiliary video stream arranged for reverse trick mode playback from a video stream including a plurality of uni-directional predicted frames, the method including producing the auxiliary video stream by performing the following steps copying each uni-directional predicted frame included in the video stream into a memory, thereby producing a plurality of copied frames in the memory, replacing each one of the plurality of copied frames with one corresponding supplemental frame, thereby producing a plurality of corresponding supplemental frames, and producing a copy of the video stream arranged in reverse processing order, the producing a copy including replacing each frame which corresponds to one of the plurality of copied frames with the one corresponding supplemental frame from among the plurality of corresponding supplemental frames. Related methods and systems are also described.

Abstract translation: 一种用于产生由包括多个单向预测帧的视频流反向特技模式重放的辅助视频流的制造方法，该方法包括：通过执行以下步骤来产生辅助视频流：复制包括在每个单向预测帧中的每个单向预测帧 视频流进入存储器，从而在存储器中产生多个复制的帧，用一个对应的补充帧替换多个复制帧中的每一个，从而产生多个对应的补充帧，并产生视频流的副本 以反向处理顺序排列，产生一个副本，包括从多个对应的补充帧中用一个对应的补充帧替换对应于多个复制帧之一的每个帧。 还描述了相关方法和系统。

公开(公告)号：US08641691B2

公开(公告)日：2014-02-04

申请号：US11904411

申请日：2007-09-27

Applicant: David Fink ,  David Heagle ,  Sharon A. Mulligan

Inventor： David Fink ,  David Heagle ,  Sharon A. Mulligan

IPC: A61F13/00

CPC classification number: A61F13/53 ,  A61F2013/530481 ,  A61M1/0001 ,  A61M1/0015 ,  A61M1/0023 ,  A61M1/0056 ,  A61M1/0072 ,  A61M1/0088 ,  A61M1/009 ,  A61M2205/15 ,  A61M2209/082 ,  A61M2209/088

Abstract: A portable system for subatmospheric pressure therapy in connection with healing a surgical wound, includes a wound dressing dimensioned for positioning relative to a wound bed of a subject, a portable subatmospheric pressure mechanism dimensioned to be carried or worn by the subject and a container for collecting exudates from the wound bed removed under the subatmospheric pressure supplied by the subatmospheric pressure mechanism. The portable subatmospheric pressure mechanism includes a housing, a subatmospheric pressure source disposed within the housing and in fluid communication with the wound dressing to supply subatmospheric pressure to the wound dressing and a power source mounted to or within the housing for supplying power to actuate the subatmospheric pressure source.

Abstract translation: 涉及愈合外科伤口的低于大气压力治疗的便携式系统包括用于相对于受试者的伤口床定位的伤口敷料，被设计为被检体携带或佩戴的便携式低于大气压力的机构，以及用于收集的容器 在由低于大气压力的机构提供的低于大气压的压力下，从伤口床排出的渗出液。 便携式低于大气压的压力机构包括壳体，低于大气压的压力源，其设置在壳体内并与伤口敷料流体连通以向伤口敷料提供低于大气压力的电源，以及安装到壳体内或壳体内的动力源，用于提供动力以致动低于大气压 压力源。

公开(公告)号：US07772252B2

公开(公告)日：2010-08-10

申请号：US12425731

申请日：2009-04-17

Applicant: James Hendrix ,  Horst Hemmerle ,  Matthias Urmann ,  Gregory M Shutske ,  Joseph T Strupczewski ,  Kenneth J Bordeau ,  John G Jurcak ,  Thaddeus Nieduzak ,  Sharon A. Jackson ,  Paul Angell ,  James P Carey ,  George Lee ,  David Fink ,  Jean-Francois Sabuco ,  Yulin Chiang ,  Nicola Collar

Inventor： James Hendrix ,  Horst Hemmerle ,  Matthias Urmann ,  Gregory M Shutske ,  Joseph T Strupczewski ,  Kenneth J Bordeau ,  John G Jurcak ,  Thaddeus Nieduzak ,  Sharon A. Jackson ,  Paul Angell ,  James P Carey ,  George Lee ,  David Fink ,  Jean-Francois Sabuco ,  Yulin Chiang ,  Nicola Collar

IPC: A61K31/4535 ,  C07D409/04 ,  C07D409/14 ,  C07D495/04

CPC classification number: A61K31/496 ,  C07D209/08 ,  C07D213/74 ,  C07D215/40 ,  C07D231/12 ,  C07D233/56 ,  C07D239/42 ,  C07D241/04 ,  C07D241/20 ,  C07D249/08 ,  C07D261/20 ,  C07D295/14 ,  C07D295/155 ,  C07D307/66 ,  C07D307/68 ,  C07D317/58 ,  C07D333/58 ,  C07D333/66 ,  C07D401/04 ,  C07D401/14 ,  C07D403/04 ,  C07D403/12 ,  C07D405/04 ,  C07D409/04 ,  C07D409/12 ,  C07D409/14 ,  C07D413/04 ,  C07D413/12 ,  C07D413/14 ,  C07D471/06 ,  C07D495/04 ,  C07D498/04

Abstract: The invention relates to heterocyclic substituted carbonyl derivatives that display selective binding to dopamine D3 receptors. In another aspect, the invention relates to a method for treating central nervous system disorders associated with the dopamine D3 receptor activity in a patient in need of such treatment comprising administering to the subject a therapeutically effective amount of said compounds for alleviation of such disorder. The central nervous system disorders that may be treated with these compounds include Psychotic Disorders, Substance Dependence, Substance Abuse, Dyskinetic Disorders (e.g. Parkinson's Disease, Parkinsonism, Neuroleptic-Induced Tardive Dyskinesia, Gilles de la Tourette Syndrome and Huntington's Disease), Dementia, Anxiety Disorders, Sleep Disorders, Circadian Rhythm Disorders and Mood Disorders. The subject invention is also directed towards processes for the preparation of the compounds described herein as well as methods for making and using the compounds as imaging agents for dopamine D3 receptors.

Abstract translation: 本发明涉及显示与多巴胺D3受体的选择性结合的杂环取代的羰基衍生物。 另一方面，本发明涉及一种治疗需要这种治疗的患者中与多巴胺D3受体活性相关的中枢神经系统障碍的方法，其包括向受试者施用治疗有效量的所述化合物以减轻这种病症。 可能用这些化合物治疗的中枢神经系统疾病包括心理障碍，物质依赖性，物质滥用，运动障碍（例如帕金森病，帕金森综合征，神经灵敏诱导的迟发性运动障碍，杜氏综合征和亨廷顿疾病），痴呆，焦虑 疾病，睡眠障碍，昼夜节律紊乱和情绪障碍。 本发明还涉及本文所述化合物的制备方法以及制备和使用化合物作为多巴胺D3受体的显像剂的方法。

公开(公告)号：US20080082059A1

公开(公告)日：2008-04-03

申请号：US11904411

申请日：2007-09-27

Applicant: David Fink ,  David Heagle ,  Sharon Mulligan

Inventor： David Fink ,  David Heagle ,  Sharon Mulligan

IPC: A61F13/40

CPC classification number: A61F13/53 ,  A61F2013/530481 ,  A61M1/0001 ,  A61M1/0015 ,  A61M1/0023 ,  A61M1/0056 ,  A61M1/0072 ,  A61M1/0088 ,  A61M1/009 ,  A61M2205/15 ,  A61M2209/082 ,  A61M2209/088

Abstract: A portable system for subatmospheric pressure therapy in connection with healing a surgical wound, includes a wound dressing dimensioned for positioning relative to a wound bed of a subject, a portable subatmospheric pressure mechanism dimensioned to be carried or worn by the subject and a container for collecting exudates from the wound bed removed under the subatmospheric pressure supplied by the subatmospheric pressure mechanism. The portable subatmospheric pressure mechanism includes a housing, a subatmospheric pressure source disposed within the housing and in fluid communication with the wound dressing to supply subatmospheric pressure to the wound dressing and a power source mounted to or within the housing for supplying power to actuate the subatmospheric pressure source.

Abstract translation: 涉及愈合外科伤口的低于大气压力治疗的便携式系统包括用于相对于受试者的伤口床定位的伤口敷料，被设计为被检体携带或佩戴的便携式低于大气压力的机构，以及用于收集的容器 在由低于大气压力的机构提供的低于大气压的压力下，从伤口床排出的渗出液。 便携式低于大气压的压力机构包括壳体，低于大气压的压力源，其设置在壳体内并与伤口敷料流体连通以向伤口敷料提供低于大气压力的电源，以及安装到壳体内或壳体内的动力源，用于提供动力以致动低于大气压 压力源。