-
公开(公告)号:US20190200801A1
公开(公告)日:2019-07-04
申请号:US16298931
申请日:2019-03-11
申请人: David Harper
发明人: David Harper
IPC分类号: A47J31/043 , A47J31/20
CPC分类号: A47J31/043 , A47J31/20
摘要: A beverage brewing device is configured to brew beverages such as coffee and tea. A brewing canister having a filter at a bottom end is held partially within a receiving beaker, and a seal is created between the canister outer surface and the beaker inner surface. Brewing media such as coffee grounds and brewing fluid such as hot water are added to the canister, mixed, and allowed to brew. At a desired time, the receiving beaker is moved relative to the brewing canister so that the brewing canister is partially removed from the receiving beaker. As such, a vacuum is formed between the bottom end of the brewing canister and the receiving beaker. The filter stops brewing media from flowing into the receiving beaker, but the vacuum draws the brewed beverage through the brewing media and filter and into the receiving beaker.
-
公开(公告)号:US08105579B2
公开(公告)日:2012-01-31
申请号:US12897741
申请日:2010-10-04
申请人: James Soothill , Catherine Hawkins , David Harper
发明人: James Soothill , Catherine Hawkins , David Harper
IPC分类号: A01N63/00 , A61K39/38 , A61K39/40 , A61K39/108
CPC分类号: A61K35/76 , A61K31/424 , A61K31/43 , A61K38/00 , A61K38/51 , A61K45/06 , C07K14/21 , C07K16/1214 , C12N2795/00031 , C12N2795/00032 , A61K2300/00
摘要: The present invention relates in its broadest aspect to combined phage/antibiotic therapy. More particularly, it relates to use of (i) one or more bacteriophages and (ii) one or more antibiotics in the manufacture of a combined product for simultaneous, separate or sequential administration of (i) and (ii) to treat a bacterial infection characterized by biofilm formation, for example an infection comprising or consisting of P. aeruginosa. Treatment in this context may be either therapeutic or prophylactic treatment. Also provided are deposited bacteriophages each exhibiting different strain specificity against P. aeruginosa and combinations of such bacteriophages, e.g. a panel of six deposited bacteriophages which was found to be effective against a high percentage of clinical isolates of P. aeruginosa from canine ear infections.
摘要翻译: 本发明最广泛地涉及联合噬菌体/抗生素治疗。 更具体地说,本发明涉及(i)一种或多种噬菌体的用途和(ii)一种或多种抗生素在制造用于同时,分开或依次施用(i)和(ii)的组合产品中以治疗细菌感染 其特征在于生物膜形成,例如包含铜绿假单胞菌或由铜绿假单胞菌组成的感染。 在本文中的治疗可以是治疗性或预防性治疗。 还提供了各自对铜绿假单胞菌显示不同的菌株特异性的沉积噬菌体和这种噬菌体的组合,例如, 一组六个沉积的噬菌体被发现对来自犬耳感染的高百分比的铜绿假单胞菌临床分离株有效。
-
公开(公告)号:US10694883B2
公开(公告)日:2020-06-30
申请号:US16298931
申请日:2019-03-11
申请人: David Harper
发明人: David Harper
IPC分类号: A47J31/043 , A47J31/20
摘要: A beverage brewing device is configured to brew beverages such as coffee and tea. A brewing canister having a filter at a bottom end is held partially within a receiving beaker, and a seal is created between the canister outer surface and the beaker inner surface. Brewing media such as coffee grounds and brewing fluid such as hot water are added to the canister, mixed, and allowed to brew. At a desired time, the receiving beaker is moved relative to the brewing canister so that the brewing canister is partially removed from the receiving beaker. As such, a vacuum is formed between the bottom end of the brewing canister and the receiving beaker. The filter stops brewing media from flowing into the receiving beaker, but the vacuum draws the brewed beverage through the brewing media and filter and into the receiving beaker.
-
公开(公告)号:US08475787B2
公开(公告)日:2013-07-02
申请号:US12529876
申请日:2008-03-07
申请人: David Harper
发明人: David Harper
IPC分类号: A01N63/00 , A61K39/108 , A61K39/00 , A61K45/00 , A61K47/00
CPC分类号: A61K35/76 , A61K31/407 , A61K31/427 , A61K31/431 , A61K31/496 , A61K31/546 , A61K31/7036 , A61K38/12 , C12N7/00 , C12N2795/00032 , C12Q1/025 , A61K2300/00
摘要: The invention relates to use of one or more bacteriophages in vivo in a human or animal in order to induce sensitivity to chemical antibiotics in bacterial cells, where such susceptibility is heritable, independent of continuing bacteriophage metabolism within those cells, and does not relate to the destruction of a biofilm to induce such sensitivity.
摘要翻译: 本发明涉及一种或多种噬菌体在人或动物体内的用途,以便诱导对细菌细胞中的化学抗生素的敏感性,其中这种易感性是可遗传的,而与这些细胞内的持续噬菌体代谢无关,并且与 破坏生物膜以诱导这种敏感性。
-
公开(公告)号:US07807149B2
公开(公告)日:2010-10-05
申请号:US10565347
申请日:2004-07-23
申请人: James Soothill , Catherine Hawkins , David Harper
发明人: James Soothill , Catherine Hawkins , David Harper
IPC分类号: A01N63/00 , A61K39/38 , A61K39/40 , A61K39/108
CPC分类号: A61K35/76 , A61K31/424 , A61K31/43 , A61K38/00 , A61K38/51 , A61K45/06 , C07K14/21 , C07K16/1214 , C12N2795/00031 , C12N2795/00032 , A61K2300/00
摘要: The present invention relates in its broadest aspect to combined phage/antibiotic therapy. More particularly, it relates to use of (i) one or more bacteriophages and (ii) one or more antibiotics in the manufacture of a combined product for simultaneous, separate or sequential administration of (i) and (ii) to treat a bacterial infection characterized by biofilm formation, for example an infection comprising or consisting of P. aeruginosa. Treatment in this context may be either therapeutic or prophylactic treatment. Also provided are deposited bacteriophages each exhibiting different strain specificity against P. aeruginosa and combinations of such bacteriophages, e.g. a panel of six deposited bacteriophages which was found to be effective against a high percentage of clinical isolates of P. aeruginosa from canine ear infections.
摘要翻译: 本发明最广泛地涉及联合噬菌体/抗生素治疗。 更具体地说,本发明涉及(i)一种或多种噬菌体的用途和(ii)一种或多种抗生素在制造用于同时,分开或依次施用(i)和(ii)的组合产品中以治疗细菌感染 其特征在于生物膜形成,例如包含铜绿假单胞菌或由铜绿假单胞菌组成的感染。 在本文中的治疗可以是治疗性或预防性治疗。 还提供了各自对铜绿假单胞菌显示不同的菌株特异性的沉积噬菌体和这种噬菌体的组合,例如, 一组六个沉积的噬菌体被发现对来自犬耳感染的高百分比的铜绿假单胞菌的临床分离株有效。
-
公开(公告)号:US20080256786A1
公开(公告)日:2008-10-23
申请号:US12169426
申请日:2008-07-08
申请人: David Harper
发明人: David Harper
IPC分类号: H01F7/06
CPC分类号: G11B5/584 , Y10T29/4902 , Y10T29/49025 , Y10T29/49027 , Y10T29/4903 , Y10T29/49032
摘要: A method for assembling an actuator assembly includes providing a first housing portion and a second housing portion; providing a coil, a pole piece, a magnet, and a completed beam; positioning the coil, pole piece, magnet, and completed beam between the housing portions; and coupling the housing portions together.
摘要翻译: 一种用于组装致动器组件的方法,包括提供第一壳体部分和第二壳体部分; 提供线圈,极片,磁体和完成的光束; 将线圈,极片,磁体和完成的波束定位在壳体部分之间; 以及将所述壳体部分联接在一起。
-
公开(公告)号:US20070053111A1
公开(公告)日:2007-03-08
申请号:US11218704
申请日:2005-09-02
申请人: David Harper
发明人: David Harper
IPC分类号: G11B5/55
CPC分类号: G11B5/584 , Y10T74/18568
摘要: An actuator includes a leadscrew and a helical gear engaging the leadscrew, the helical gear having journals extending from opposite ends thereof. A carriage operatively engages the journals. A relative rotation between the leadscrew and the helical gear creates a relative movement between the carriage and the leadscrew in a direction parallel to an axis of the leadscrew.
摘要翻译: 致动器包括导螺杆和接合丝杠的斜齿轮,螺旋齿轮具有从其相对端延伸的轴颈。 一个马车可操作地接合这些期刊。 丝杠和螺旋齿轮之间的相对旋转在平行于丝杠的轴线的方向上在托架和丝杠之间产生相对运动。
-
公开(公告)号:US06860684B2
公开(公告)日:2005-03-01
申请号:US10643133
申请日:2003-08-18
摘要: A loading system for securing cargo with, typically, at least two spaced forwardly located pin and receptacle assemblies and at least two spaced rearwardly located tensioning systems.
摘要翻译: 用于固定货物的装载系统,通常具有至少两个间隔开的向前定位的销和插座组件以及至少两个间隔开的向后定位的张紧系统。
-
公开(公告)号:US5046284A
公开(公告)日:1991-09-10
申请号:US580074
申请日:1990-09-10
申请人: David Harper
发明人: David Harper
IPC分类号: B60J1/18
摘要: An anti-theft device for a vehicle having a window pane within a rim forming an opening in the vehicle. An interior frame has a plurality of openings extending therethrough. An exterior frame, capable of mating with the interior frame, has a recess extending around the frame and a plurality of openings extending into but not through the exterior frame. A sheath, extending around and receiving the edge of the window pane, has at least one handle extending therefrom. A latch extends from the sheath and is enagable with the interior frame. Fasteners are receivable through the interior frame openings and into the exterior frames openings so that the window pane within the surrounding sheath may be placed in the recess and engaged with the interior frame by use of the latch.
摘要翻译: 一种用于车辆的防盗装置,其具有在车轮内形成开口的边缘内的窗玻璃。 内部框架具有穿过其延伸的多个开口。 能够与内部框架配合的外框架具有围绕框架延伸的凹部和延伸到外框架中但不穿过框架的多个开口。 围绕并接收窗玻璃的边缘延伸的护套具有从其延伸的至少一个手柄。 闩锁从护套延伸并且可与内框架一起使用。 紧固件可通过内部框架开口接纳到外部框架开口中,使得周围护套内的窗玻璃可以被放置在凹部中并且通过使用闩锁与内部框架接合。
-
公开(公告)号:US10226147B2
公开(公告)日:2019-03-12
申请号:US15400869
申请日:2017-01-06
申请人: David Harper
发明人: David Harper
IPC分类号: A47J31/043 , A47J31/20
摘要: A beverage brewing device is configured to brew beverages such as coffee and tea. A brewing canister having a filter at a bottom end is held partially within a receiving beaker, and a seal is created between the canister outer surface and the beaker inner surface. Brewing media such as coffee grounds and brewing fluid such as hot water are added to the canister, mixed, and allowed to brew. At a desired time, the receiving beaker is moved relative to the brewing canister so that the brewing canister is partially removed from the receiving beaker. As such, a vacuum is formed between the bottom end of the brewing canister and the receiving beaker. The filter stops brewing media from flowing into the receiving beaker, but the vacuum draws the brewed beverage through the brewing media and filter and into the receiving beaker.
-
-
-
-
-
-
-
-
-