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公开(公告)号：US06448037B1
公开(公告)日：2002-09-10
申请号：US09026017
申请日：1998-02-20
IPC分类号： C07H2104
CPC分类号： C12N9/1288 , A61K38/00 , A61K39/00 , C12Y207/08005
摘要： The invention provides pgsA polypeptides and polynucleotides encoding pgsA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pgsA polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供pgsA多肽和编码pgsA多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用pgsA多肽筛选抗菌化合物的方法。
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公开(公告)号：US07202071B2
公开(公告)日：2007-04-10
申请号：US10437581
申请日：2003-05-14
申请人： Sanjoy Biswas , James Raymond Brown , Christine Debouck , Deborah Dee Jaworski , Elizabeth Jane Lawlor , Jeffrey Mooney , Lisa Kathleen Shilling , Min Wang , Richard Lloyd Warren , Magdalena Zalacain , Yi Yi Zhong , John Peter Throup , Karen Anne Ingraham , Alison Frances Chalker , David John Holmes , Christopher Michael Traini
发明人： Sanjoy Biswas , James Raymond Brown , Christine Debouck , Deborah Dee Jaworski , Elizabeth Jane Lawlor , Jeffrey Mooney , Lisa Kathleen Shilling , Min Wang , Richard Lloyd Warren , Magdalena Zalacain , Yi Yi Zhong , John Peter Throup , Karen Anne Ingraham , Alison Frances Chalker , David John Holmes , Christopher Michael Traini
摘要： The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供第p多肽和编码第p多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用第p多肽筛选抗菌化合物的方法。
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公开(公告)号：US06303771B1
公开(公告)日：2001-10-16
申请号：US09080643
申请日：1998-05-18
申请人： Sanjoy Biswas , James Raymond Brown , Christine Debouck , Deborah Dee Jaworski , Elizabeth Jane Lawlor , Jeffrey Mooney , Lisa Kathleen Shilling , Min Wang , Richard Lloyd Warren , Magdalena Zalacain , Yi Yi Zhong , John Peter Throup , Karen Anne Ingraham , Alison Frances Chalker , David John Holmes , Christopher Michael Traini
发明人： Sanjoy Biswas , James Raymond Brown , Christine Debouck , Deborah Dee Jaworski , Elizabeth Jane Lawlor , Jeffrey Mooney , Lisa Kathleen Shilling , Min Wang , Richard Lloyd Warren , Magdalena Zalacain , Yi Yi Zhong , John Peter Throup , Karen Anne Ingraham , Alison Frances Chalker , David John Holmes , Christopher Michael Traini
IPC分类号： C12N1531
摘要： The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供第p多肽和编码第p多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用第p多肽筛选抗菌化合物的方法。
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公开(公告)号：US06458572B1
公开(公告)日：2002-10-01
申请号：US09631547
申请日：2000-08-03
IPC分类号： C12N910
CPC分类号： C12N9/1288 , A61K38/00 , A61K39/00 , C12Y207/08005
摘要： The invention provides Phosphatidylglycerophosphate Synthase polypeptides from Staphylococcus aureus (“pgsA polypeptides”). Also provided are methods for utilizing pgsA polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了来自金黄色葡萄球菌的磷脂酰甘油磷酸合成酶多肽（“pgsA多肽”）。 还提供了利用pgsA多肽筛选抗菌化合物的方法。
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公开(公告)号：US06228625B1
公开(公告)日：2001-05-08
申请号：US09273686
申请日：1999-03-22
申请人： Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Chi Young So , Richard Lloyd Warren , Magdalena Zalacain
发明人： Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Chi Young So , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号： C12N900
CPC分类号： C12Q1/6876 , A61K38/00 , C07K14/3156
摘要： The invention provides metK polypeptides and polynucleotides encoding metK polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing metK polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了metK多肽和编码metK多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用metK多肽来筛选抗菌化合物的方法。
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公开(公告)号：US06399343B1
公开(公告)日：2002-06-04
申请号：US09574912
申请日：2000-05-19
申请人： Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , Richard Lloyd Warren , Magdalena Zalacain , Chi Young So , Christopher M Traini , David John Holmes , Karen Anne Ingraham , Thomas B Mathie
发明人： Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , Richard Lloyd Warren , Magdalena Zalacain , Chi Young So , Christopher M Traini , David John Holmes , Karen Anne Ingraham , Thomas B Mathie
IPC分类号： C12N900
CPC分类号： C07K14/3156 , A61K38/00 , A61K39/00 , A61K48/00 , Y10S435/885
摘要： The invention provides infB polypeptides and polynucleotides encoding infB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing in polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供编码infB多肽的infB多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了在多肽中利用筛选抗菌化合物的方法。
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公开(公告)号：US06350600B1
公开(公告)日：2002-02-26
申请号：US09627769
申请日：2000-07-28
申请人： Sanjoy Biswas , James Raymond Brown , Chi Young So , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain
发明人： Sanjoy Biswas , James Raymond Brown , Chi Young So , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号： C12N900
CPC分类号： C12N9/1007 , A61K38/00 , A61K39/00 , A61K48/00
摘要： The invention provides trmA methyl transferase (trmD) polypeptides and polynucleotides encoding trmD polypeptides and methods for producing such polypeptides by recominant techniques from strepococcus pneumoniae. Also provided are methods for utilizing polypepides to screen for antibacterial compounds.
摘要翻译： 本发明提供trmA甲基转移酶（trmD）多肽和编码trmD多肽的多核苷酸以及通过来自肺炎链球菌的重组技术产生此类多肽的方法。 还提供了利用多肽来筛选抗菌化合物的方法。
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公开(公告)号：US06245542B1
公开(公告)日：2001-06-12
申请号：US09306276
申请日：1999-05-06
申请人： Sanjoy Biswas , Alexander Bryant , James Raymond Brown , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Chi Young So , Stephanie Van Horn , Richard Lloyd Warren , Magdalena Zalacain
发明人： Sanjoy Biswas , Alexander Bryant , James Raymond Brown , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Chi Young So , Stephanie Van Horn , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号： C12N910
CPC分类号： C12N9/1007 , A61K38/00
摘要： The invention provides yfjO polypeptides and polynucleotides encoding yfjO polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing yfjO polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了yfjO多肽和编码yfjO多肽的多核苷酸，以及通过重组技术产生此类多肽的方法。 还提供了利用yfj多肽筛选抗菌化合物的方法。
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公开(公告)号：US06340564B1
公开(公告)日：2002-01-22
申请号：US09237111
申请日：1999-01-26
申请人： Karen Anne Ingraham , Chi Yong So , Stephanie Van Horn , Alison Francis Chalker , David John Holmes , Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Patrick Vernon Warren , Richard Lloyd Warren , Magdalena Zalacain
发明人： Karen Anne Ingraham , Chi Yong So , Stephanie Van Horn , Alison Francis Chalker , David John Holmes , Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Patrick Vernon Warren , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号： C12Q168
CPC分类号： C07K14/3156
摘要： The invention provides yhxB polypeptides and polynucleotides encoding yhxB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing yhxB polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了yhxB多肽和编码yhxB多肽的多核苷酸以及通过重组技术产生这种多肽的方法。 还提供了利用yhxB多肽筛选抗菌化合物的方法。
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公开(公告)号：US6110685A
公开(公告)日：2000-08-29
申请号：US283763
申请日：1999-04-01
申请人： Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , Richard Lloyd Warren , Magdalena Zalacain , Chi Young So , Christopher M Traini , David John Holmes , Karen Anne Ingraham , Thomas B Mathie
发明人： Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , Richard Lloyd Warren , Magdalena Zalacain , Chi Young So , Christopher M Traini , David John Holmes , Karen Anne Ingraham , Thomas B Mathie
CPC分类号： C07K14/3156 , A61K38/00 , A61K39/00 , A61K48/00 , Y10S435/885
摘要： The invention provides infB polypeptides and polynucleotides encoding in polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing infB polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了在多肽中编码的infB多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用infB多肽筛选抗菌化合物的方法。
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