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    Systems and methods using asymmetric multiple electrode arrays
    1.
    发明授权
    Systems and methods using asymmetric multiple electrode arrays 失效
    使用不对称多电极阵列的系统和方法

    公开(公告)号：US5968040A

    公开(公告)日：1999-10-19

    申请号：US728698

    申请日：1996-10-28

    申请人： David K. Swanson ,  Sidney D. Fleischman ,  Dorin Panescu ,  James G. Whayne ,  Thomas F. Kordis

    发明人： David K. Swanson ,  Sidney D. Fleischman ,  Dorin Panescu ,  James G. Whayne ,  Thomas F. Kordis

    IPC分类号： A61N1/00 ,  A61B17/39

    CPC分类号： A61N1/00

    摘要： Systems and methods support arrays of multiple electrodes in asymmetric pattern, either radially, or axially, or both. Radial asymmetry makes it possible provide localized density of electrodes. Axial asymmetry makes it possible to locate electrodes in a pattern that closely conforms to the irregular contours of an interior body cavity, like the heart. In a preferred embodiment, the systems and methods operate the multiple electrode arrays to form continuous lesion patterns.

    摘要翻译： 系统和方法以径向或轴向或两者不对称的方式支持多个电极的阵列。 径向不对称使得可能提供电极的局部密度。 轴向不对称使得可以将电极定位成与内部体腔的不规则轮廓紧密一致的图案，如心脏。 在优选实施例中，系统和方法操作多个电极阵列以形成连续的病变图案。

    Systems and methods employing structures having asymmetric mechanical properties to support diagnostic or therapeutic elements in contact with tissue in interior body regions
    2.
    发明授权
    Systems and methods employing structures having asymmetric mechanical properties to support diagnostic or therapeutic elements in contact with tissue in interior body regions 失效
    使用具有不对称机械性能的结构以支持与内部身体区域中的组织接触的诊断或治疗元件的系统和方法

    公开(公告)号：US6014590A

    公开(公告)日：2000-01-11

    申请号：US742564

    申请日：1996-10-28

    申请人： James G. Whayne ,  Sidney D. Fleischman ,  Dorin Panescu ,  Thomas F. Kordis ,  David K. Swanson

    发明人： James G. Whayne ,  Sidney D. Fleischman ,  Dorin Panescu ,  Thomas F. Kordis ,  David K. Swanson

    IPC分类号： A61B17/39

    摘要： Structures having asymmetric mechanical properties provide enhanced ability to support therapeutic or diagnostic elements in contact with tissue in an interior body region. The support structure includes a first region, which exhibits a first mechanical property affecting tissue contact, and a second region spaced from the first region about the axis, which exhibits a second mechanical property, different than the first mechanical property, affecting tissue contact. In a preferred embodiment, the first and second mechanical properties correlate with stiffness of the respective first and second regions, with the first region being more flexible (i.e., less stiff) than the second region. The first region, due to its greater flexibility, is more conformal to tissue than the second region. The less flexible (i.e., more stiff) second region imparts greater force against the tissue to urge the more flexible first region toward intimate tissue contact. In a preferred embodiment, the more flexible first region carries at least one therapeutic or diagnostic element.

    摘要翻译： 具有不对称机械特性的结构提供增强的能力，以支持与内部身体区域中的组织接触的治疗或诊断元件。 支撑结构包括表现出影响组织接触的第一机械特性的第一区域以及围绕轴线与第一区域隔开的第二区域，该第二区域具有影响组织接触的第二机械特性，该第二机械特性不同于第一机械特性。 在优选实施例中，第一和第二机械特性与相应的第一和第二区域的刚度相关，其中第一区域比第二区域更加柔性（即，较不硬）。 第一个区域由于其更大的灵活性，比第二个区域更适合组织。 较不柔性（即更硬）的第二区域赋予组织更大的力以促使更柔性的第一区域朝向紧密的组织接触。 在优选实施方案中，更灵活的第一区域携带至少一种治疗或诊断元件。

    Structures for supporting porous electrode elements
    7.
    发明授权
    Structures for supporting porous electrode elements 失效

    公开(公告)号：US06668198B2

    公开(公告)日：2003-12-23

    申请号：US09996235

    申请日：2001-11-27

    申请人： David K Swanson ,  Russell B Thompson ,  Sidney D Fleischman ,  Dorin Panescu ,  James G Whayne

    发明人： David K Swanson ,  Russell B Thompson ,  Sidney D Fleischman ,  Dorin Panescu ,  James G Whayne

    IPC分类号： A61N100

    CPC分类号： A61N1/06 ,  A61B18/1492 ,  A61B2018/00148 ,  A61B2018/00214

    摘要： A catheter assembly comprising a elongated, flexible support structure having an axis. The assembly also includes an elongated porous electrode assembly carried by the support structure along the axis for contact with tissue. The elongated porous electrode assembly comprises a wall having an exterior peripherally surrounding an interior area, a lumen to convey a medium containing ions into the interior area, and an element coupling the medium within the interior area to a source of electrical energy. At least a portion of the wall comprising a porous material is sized to allow passage of ions contained in the medium to thereby enable ionic transport of electrical energy through the porous material to the exterior of the wall to form a continuous elongated lesion pattern in tissue contacted by the wall. The support structure can have a curvilinear geometry, e.g., a loop shape, and the elongated porous electrode assembly conforms to the curvilinear geometry.

    Structures for supporting porous electrode elements
    10.
    发明授权
    Structures for supporting porous electrode elements 失效
    用于支撑多孔电极元件的结构

    公开(公告)号：US6076012A

    公开(公告)日：2000-06-13

    申请号：US770572

    申请日：1996-12-19

    申请人： David K Swanson ,  Russell B Thompson ,  Sidney D Fleischman ,  Dorin Panescu ,  James G Whayne

    发明人： David K Swanson ,  Russell B Thompson ,  Sidney D Fleischman ,  Dorin Panescu ,  James G Whayne

    IPC分类号： A61B18/14 ,  A61N1/06 ,  A61N1/30 ,  A61N1/00 ,  A61B17/36

    CPC分类号： A61N1/06 ,  A61B18/1492 ,  A61B2018/00148 ,  A61B2018/00214

    摘要： A catheter assembly comprising a elongated, flexible support structure having an axis. The assembly also includes an elongated porous electrode assembly carried by the support structure along the axis for contact with tissue. The elongated porous electrode assembly comprises a wall having an exterior peripherally surrounding an interior area, a lumen to convey a medium containing ions into the interior area, and an element coupling the medium within the interior area to a source of electrical energy. At least a portion of the wall comprising a porous material is sized to allow passage of ions contained in the medium to thereby enable ionic transport of electrical energy through the porous material to the exterior of the wall to form a continuous elongated lesion pattern in tissue contacted by the wall. The support structure can have a curvilinear geometry, e.g., a loop shape, and the elongated porous electrode assembly conforms to the curvilinear geometry. The assembly also includes comprises a sheath carried by the support structure having a slot extending along the axis of the support structure, wherein the electrode assembly is adapted to bend outwardly through the slot.

    摘要翻译： 导管组件，其包括具有轴的细长的柔性支撑结构。 组件还包括由支撑结构承载的细长多孔电极组件，沿着轴线与组织接触。 细长的多孔电极组件包括具有周围围绕内部区域的外部的外壁，用于将含有离子的介质输送到内部区域的内腔，以及将内部区域内的介质耦合到电能源的元件。 包含多孔材料的壁的至少一部分的尺寸设定成允许包含在介质中的离子通过，从而使得电能通过多孔材料离子传递到壁的外部，以在组织接触中形成连续的细长损伤图案 在墙上。 支撑结构可以具有曲线几何形状，例如环形，并且细长多孔电极组件符合曲线几何形状。 组件还包括由支撑结构承载的护套，其具有沿着支撑结构的轴线延伸的槽，其中电极组件适于向外弯曲穿过槽。