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公开(公告)号：US07851204B2
公开(公告)日：2010-12-14
申请号：US11450855
申请日：2006-06-09
CPC分类号： C12M23/12 , B01L3/50853 , B01L2200/0689 , B01L2300/042 , B01L2300/044 , B01L2300/048 , B01L2300/049 , B01L2300/123 , B01L2400/0605 , B01L2400/0611 , C12M23/38 , C12M37/04
摘要： A closure for a microreactor includes a cap that is configured to be inserted into a well of the microreactor. The cap, or at least a portion of the cap, is compliant so as to form a seal with the well when the cap is inserted. The cap includes an aperture that provides an airway between the inside of the well to the external environment when the cap is inserted into the well. A porous plug is inserted in the aperture, e.g., either directly or in tube that extends through the aperture. The porous plug permits gas within the well to pass through the aperture while preventing liquids from passing through to reduce evaporation and preventing microbes from passing through to provide a sterile environment. A one-way valve may also be used to help control the environment in the well.
摘要翻译： 用于微反应器的盖子包括构造成插入微反应器的孔中的盖。 帽或帽的至少一部分是柔顺的，以便当盖被插入时与孔形成密封。 所述盖包括孔，当所述盖插入所述孔中时，所述孔在井的内部与外部环境之间提供气道。 多孔塞插入到孔中，例如直接地或在管中延伸穿过孔。 多孔插塞允许孔内的气体通过孔，同时防止液体通过以减少蒸发并防止微生物通过以提供无菌环境。 也可以使用单向阀来帮助控制井中的环境。
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公开(公告)号：US20080014629A1
公开(公告)日：2008-01-17
申请号：US11450855
申请日：2006-06-09
IPC分类号： C12M3/00
CPC分类号： C12M23/12 , B01L3/50853 , B01L2200/0689 , B01L2300/042 , B01L2300/044 , B01L2300/048 , B01L2300/049 , B01L2300/123 , B01L2400/0605 , B01L2400/0611 , C12M23/38 , C12M37/04
摘要： A closure for a microreactor includes a cap that is configured to be inserted into a well of the microreactor. The cap, or at least a portion of the cap, is compliant so as to form a seal with the well when the cap is inserted. The cap includes an aperture that provides an airway between the inside of the well to the external environment when the cap is inserted into the well. A porous plug is inserted in the aperture, e.g., either directly or in tube that extends through the aperture. The porous plug permits gas within the well to pass through the aperture while preventing liquids from passing through to reduce evaporation and preventing microbes from passing through to provide a sterile environment. A one-way valve may also be used to help control the environment in the well.
摘要翻译： 用于微反应器的盖子包括构造成插入微反应器的孔中的盖。 帽或帽的至少一部分是柔顺的，以便当盖被插入时与孔形成密封。 所述盖包括孔，当所述盖插入所述孔中时，所述孔在井的内部与外部环境之间提供气道。 多孔塞插入到孔中，例如直接地或在管中延伸穿过孔。 多孔插塞允许孔内的气体通过孔，同时防止液体通过以减少蒸发并防止微生物通过以提供无菌环境。 也可以使用单向阀来帮助控制井中的环境。
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公开(公告)号：US20080131972A1
公开(公告)日：2008-06-05
申请号：US12026450
申请日：2008-02-05
IPC分类号： G01N33/00
CPC分类号： C12M23/12 , B01L3/50851 , B01L3/50853 , B01L2200/143 , B01L2300/049 , B01L2300/0663 , B01L2300/0829 , B01L2300/10 , B01L2300/1822 , B01L2300/1827 , C12M23/38 , C12M41/26 , C12M41/34 , Y10T436/209163
摘要： A well plate and its supporting devices provide capabilities found in larger fermenters, such as controlling the oxygen level, the pH level, and temperature of the contents of the well. The well plate includes a plurality of wells, each of which can be independently controlled. Apertures in the wells, for example, provide access for a gas supply and sensors within each well provide data relating to, e.g., oxygen and/or pH level in the well. A control system controls the gas supply for each well based on the information provided by the sensor within the well. Similarly, temperature control elements, such as a heater or cooler, is placed in thermal contact with the interior of the well, as is a temperature measurement element. A control system can independently control the temperature of the contents of the well based on information provided by the temperature measurement element for that well.
摘要翻译： 井板及其支撑装置提供在较大发酵罐中发现的能力，例如控制井的内容物的氧气含量，pH值和温度。 井板包括多个井，每个井可独立控制。 例如，孔中的孔径为气体供应提供通路，并且每个井内的传感器提供与井中的氧气和/或pH水平有关的数据。 控制系统根据由井内的传感器提供的信息来控制每个井的气体供应。 类似地，诸如加热器或冷却器的温度控制元件也被放置成与井的内部热接触，温度测量元件也是如此。 控制系统可以根据井的温度测量元件提供的信息独立地控制井的内部温度。
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公开(公告)号：US07713486B2
公开(公告)日：2010-05-11
申请号：US12024973
申请日：2008-02-01
IPC分类号： B01L3/00
CPC分类号： C12M23/12 , B01L3/50851 , B01L3/50853 , B01L2200/143 , B01L2300/049 , B01L2300/0663 , B01L2300/0829 , B01L2300/10 , B01L2300/1822 , B01L2300/1827 , C12M23/38 , C12M41/26 , C12M41/34 , Y10T436/209163
摘要： A well plate and its supporting devices provide capabilities found in larger fermenters, such as controlling the oxygen level, the pH level, and temperature of the contents of the well. The well plate includes a plurality of wells, each of which can be independently controlled. Apertures in the wells, for example, provide access for a gas supply and sensors within each well provide data relating to, e.g., oxygen and/or pH level in the well. A control system controls the gas supply for each well based on the information provided by the sensor within the well. Similarly, temperature control elements, such as a heater or cooler, is placed in thermal contact with the interior of the well, as is a temperature measurement element. A control system can independently control the temperature of the contents of the well based on information provided by the temperature measurement element for that well.
摘要翻译： 井板及其支撑装置提供在较大发酵罐中发现的能力，例如控制井的内容物的氧气含量，pH值和温度。 井板包括多个井，每个井可独立控制。 例如，孔中的孔径为气体供应提供通路，并且每个井内的传感器提供与井中的氧气和/或pH水平有关的数据。 控制系统根据由井内的传感器提供的信息来控制每个井的气体供应。 类似地，诸如加热器或冷却器的温度控制元件也被放置成与井的内部热接触，温度测量元件也是如此。 控制系统可以根据井的温度测量元件提供的信息独立地控制井的内部温度。
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公开(公告)号：US20100184199A1
公开(公告)日：2010-07-22
申请号：US12749374
申请日：2010-03-29
IPC分类号： C12M1/36
CPC分类号： C12M23/12 , B01L3/50851 , B01L3/50853 , B01L2200/143 , B01L2300/049 , B01L2300/0663 , B01L2300/0829 , B01L2300/10 , B01L2300/1822 , B01L2300/1827 , C12M23/38 , C12M41/26 , C12M41/34 , Y10T436/209163
摘要： A well plate and its supporting devices provide capabilities found in larger fermenters, such as controlling the oxygen level, the pH level, and temperature of the contents of the well. The well plate includes a plurality of wells, each of which can be independently controlled. Apertures in the wells, for example, provide access for a gas supply and sensors within each well provide data relating to, e.g., oxygen and/or pH level in the well. A control system controls the gas supply for each well based on the information provided by the sensor within the well. Similarly, temperature control elements, such as a heater or cooler, is placed in thermal contact with the interior of the well, as is a temperature measurement element. A control system can independently control the temperature of the contents of the well based on information provided by the temperature measurement element for that well.
摘要翻译： 井板及其支撑装置提供在较大发酵罐中发现的能力，例如控制井的内容物的氧气含量，pH值和温度。 井板包括多个井，每个井可独立控制。 例如，孔中的孔径为气体供应提供通路，并且每个井内的传感器提供与井中的氧气和/或pH水平有关的数据。 控制系统根据由井内的传感器提供的信息来控制每个井的气体供应。 类似地，诸如加热器或冷却器的温度控制元件也被放置成与井的内部热接触，温度测量元件也是如此。 控制系统可以根据井的温度测量元件提供的信息独立地控制井的内部温度。
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公开(公告)号：US07718134B2
公开(公告)日：2010-05-18
申请号：US12026450
申请日：2008-02-05
IPC分类号： B01L3/00
CPC分类号： C12M23/12 , B01L3/50851 , B01L3/50853 , B01L2200/143 , B01L2300/049 , B01L2300/0663 , B01L2300/0829 , B01L2300/10 , B01L2300/1822 , B01L2300/1827 , C12M23/38 , C12M41/26 , C12M41/34 , Y10T436/209163
摘要： A well plate and its supporting devices provide capabilities found in larger fermenters, such as controlling the oxygen level, the pH level, and temperature of the contents of the well. The well plate includes a plurality of wells, each of which can be independently controlled. Apertures in the wells, for example, provide access for a gas supply and sensors within each well provide data relating to, e.g., oxygen and/or pH level in the well. A control system controls the gas supply for each well based on the information provided by the sensor within the well. Similarly, temperature control elements, such as a heater or cooler, is placed in thermal contact with the interior of the well, as is a temperature measurement element. A control system can independently control the temperature of the contents of the well based on information provided by the temperature measurement element for that well.
摘要翻译： 井板及其支撑装置提供在较大发酵罐中发现的能力，例如控制井的内容物的氧气含量，pH值和温度。 井板包括多个井，每个井可独立控制。 例如，孔中的孔径为气体供应提供通路，并且每个井内的传感器提供与井中的氧气和/或pH水平有关的数据。 控制系统根据由井内的传感器提供的信息来控制每个井的气体供应。 类似地，诸如加热器或冷却器的温度控制元件也被放置成与井的内部热接触，温度测量元件也是如此。 控制系统可以根据井的温度测量元件提供的信息独立地控制井的内部温度。
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公开(公告)号：US07887766B2
公开(公告)日：2011-02-15
申请号：US12749374
申请日：2010-03-29
IPC分类号： B01L3/00
CPC分类号： C12M23/12 , B01L3/50851 , B01L3/50853 , B01L2200/143 , B01L2300/049 , B01L2300/0663 , B01L2300/0829 , B01L2300/10 , B01L2300/1822 , B01L2300/1827 , C12M23/38 , C12M41/26 , C12M41/34 , Y10T436/209163
摘要： A well plate and its supporting devices provide capabilities found in larger fermenters, such as controlling the oxygen level, the pH level, and temperature of the contents of the well. The well plate includes a plurality of wells, each of which can be independently controlled. Apertures in the wells, for example, provide access for a gas supply and sensors within each well provide data relating to, e.g., oxygen and/or pH level in the well. A control system controls the gas supply for each well based on the information provided by the sensor within the well. Similarly, temperature control elements, such as a heater or cooler, is placed in thermal contact with the interior of the well, as is a temperature measurement element. A control system can independently control the temperature of the contents of the well based on information provided by the temperature measurement element for that well.
摘要翻译： 井板及其支撑装置提供在较大发酵罐中发现的能力，例如控制井的内容物的氧气含量，pH值和温度。 井板包括多个井，每个井可独立控制。 例如，孔中的孔径为气体供应提供通路，并且每个井内的传感器提供与井中的氧气和/或pH水平有关的数据。 控制系统根据由井内的传感器提供的信息来控制每个井的气体供应。 类似地，诸如加热器或冷却器的温度控制元件也被放置成与井的内部热接触，温度测量元件也是如此。 控制系统可以根据井的温度测量元件提供的信息独立地控制井的内部温度。
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公开(公告)号：US07374725B2
公开(公告)日：2008-05-20
申请号：US10777581
申请日：2004-02-11
IPC分类号： B01L3/00
CPC分类号： C12M23/12 , B01L3/50851 , B01L3/50853 , B01L2200/143 , B01L2300/049 , B01L2300/0663 , B01L2300/0829 , B01L2300/10 , B01L2300/1822 , B01L2300/1827 , C12M23/38 , C12M41/26 , C12M41/34 , Y10T436/209163
摘要： A well plate and its supporting devices provide capabilities found in larger fermenters, such as controlling the oxygen level, the pH level, and temperature of the contents of the well. The well plate includes a plurality of wells, each of which can be independently controlled. Apertures in the wells, for example, provide access for a gas supply and sensors within each well provide data relating to, e.g., oxygen and/or pH level in the well. A control system controls the gas supply for each well based on the information provided by the sensor within the well. Similarly, temperature control elements, such as a heater or cooler, is placed in thermal contact with the interior of the well, as is a temperature measurement element. A control system can independently control the temperature of the contents of the well based on information provided by the temperature measurement element for that well.
摘要翻译： 井板及其支撑装置提供在较大发酵罐中发现的能力，例如控制井的内容物的氧气含量，pH值和温度。 井板包括多个井，每个井可独立控制。 例如，孔中的孔径为气体供应提供通路，并且每个井内的传感器提供与井中的氧气和/或pH水平有关的数据。 控制系统根据由井内的传感器提供的信息来控制每个井的气体供应。 类似地，诸如加热器或冷却器的温度控制元件也被放置成与井的内部热接触，温度测量元件也是如此。 控制系统可以根据井的温度测量元件提供的信息独立地控制井的内部温度。
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公开(公告)号：US20090302831A1
公开(公告)日：2009-12-10
申请号：US12136698
申请日：2008-06-10
申请人： Frank J. Adams , David L. Klein
发明人： Frank J. Adams , David L. Klein
IPC分类号： G01R11/48
CPC分类号： G01R21/133 , G01R21/06 , Y10T307/505 , Y10T307/511 , Y10T307/615
摘要： Power consumption at a site is monitored. An electrical load is connected to a power source by an electrical conductor. A fuel-less energy producing device is electrically connected to a junction along the electrical conductor. A current sensor is electromagnetically coupled to the electrical conductor at a sensing position between the power source and the junction to create a current sensor signal. Sensed current and voltage signals are produced from the current sensor signal. A sensed phase relationship between the sensed signals is determined and compared to a baseline phase relationship to determine the direction of current flow through the conductor. A power source signal, based on the current flowing through the conductor at the sensing position, is created. With some examples a Rogowski type differential current sensor is used. In some examples a single current sensor is used.
摘要翻译： 监控场地的功耗。 电负载通过电导体连接到电源。 无燃料能量产生装置电连接到沿导电体的连接处。 电流传感器在电源和接点之间的感测位置处电磁耦合到电导体，以产生电流传感器信号。 感测的电流和电压信号由电流传感器信号产生。 确定感测到的信号之间感测到的相位关系，并将其与基线相位关系进行比较，以确定通过导体的电流的方向。 基于在感测位置处流过导体的电流产生电源信号。 使用一些Rogowski型差动电流传感器。 在一些示例中，使用单个电流传感器。
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公开(公告)号：US07622912B1
公开(公告)日：2009-11-24
申请号：US12136698
申请日：2008-06-10
申请人： Frank J. Adams , David L. Klein
发明人： Frank J. Adams , David L. Klein
IPC分类号： G01R31/28
CPC分类号： G01R21/133 , G01R21/06 , Y10T307/505 , Y10T307/511 , Y10T307/615
摘要： Power consumption at a site is monitored. An electrical load is connected to a power source by an electrical conductor. A fuel-less energy producing device is electrically connected to a junction along the electrical conductor. A current sensor is electromagnetically coupled to the electrical conductor at a sensing position between the power source and the junction to create a current sensor signal. Sensed current and voltage signals are produced from the current sensor signal. A sensed phase relationship between the sensed signals is determined and compared to a baseline phase relationship to determine the direction of current flow through the conductor. A power source signal, based on the current flowing through the conductor at the sensing position, is created. With some examples a Rogowski type differential current sensor is used. In some examples a single current sensor is used.
摘要翻译： 监控场地的功耗。 电负载通过电导体连接到电源。 无燃料能量产生装置电连接到沿导电体的连接处。 电流传感器在电源和接点之间的感测位置处电磁耦合到电导体，以产生电流传感器信号。 感测的电流和电压信号由电流传感器信号产生。 确定感测到的信号之间感测到的相位关系，并将其与基线相位关系进行比较，以确定通过导体的电流的方向。 基于在感测位置处流过导体的电流产生电源信号。 使用一些Rogowski型差动电流传感器。 在一些示例中，使用单个电流传感器。
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