摘要:
Inhibitors of HIV membrane fusion and a method of identifying drugs or agents which inhibit binding of the N-helix coiled-coil and the C helix of HIV gp41 envelope protein.
摘要:
Described are the crystal structure of the α-helical domain of the gp41 component of HIV-1 envelope glycoprotein which represents the core of fusion-active gp41, methods of identifying and designing drugs which inhibit gp41 function and drugs which do so.
摘要:
Five-Helix protein, which comprises the three N-helices and at least two, but not three, of the three C-helices of the trimer-of-hairpin structure of HIV gp41, separated by linkers, such as amino acid residue linkers, is disclosed. Six-Helix protein, which includes the three N-helices and the three C-helices of the trimer-of-hairpin structure of HIV gp41, separated by linkers, is also disclosed.
摘要:
A request for a funds transfer is received by a sending financial institution (FI) located in a first country from a mobile network operator (MNO) for a recipient located in a second country. The funds transfer request includes the sender's mobile telephone number and transaction data, and the process includes translating the mobile telephone number into a sender's payment card account number, determining that the sender's payment card account can support the transfer amount, and transmitting the transaction data and the sender's payment card account number to a payment system. The sending FI receives a payment confirmation message that satisfies compliance with know your customer (KYC) information and anti-money laundering (AML) information requirements, and transmits a remittance confirmation message to the MNO.
摘要:
A computer platform (100) uses a tamper-proof component (120), or “trusted module”, of a computer platform in conjunction with software, preferably running within the tamper-proof component, that controls the uploading and usage of data on the platform as a generic dongle for that platform. Licensing checks can occur within a trusted environment (in other words, an environment which can be trusted to behave as the user expects); this can be enforced by integrity checking of the uploading and license-checking software. Metering records can be stored in the tamper-proof device and reported back to administrators as required. There can be an associated clearinghouse mechanism to enable registration and payment for data.
摘要:
A coring device is provided and in particular a coring device for coring cupcakes or similar food items. The coring device may comprise a body defining a channel therein; a plunger, received within the channel and configured to slide therein; and a flange, extending around at least a portion of the body. The body has a first and second end, at least one of which defines a cutting edge. The body and the flange may be a unitary construction.
摘要:
A method and system for determining distribution center or warehouse product order quantities of a slow selling product. The method includes the step of determining for each one of a plurality of stores supplied by the distribution center, a store order forecast for the slow selling product. The method generates a random beginning on-hand inventory value for stores with inventories below a minimum inventory threshold value. Store order forecasts are thereafter determined by subtracting the random beginning on-hand inventory value from store sales forecasts when the beginning on-hand inventory value is less than the minimum inventory threshold value, and subtracting the actual beginning on-hand inventory value from the store sales forecasts when the beginning on-hand inventory value is not less than the minimum inventory threshold value. The individual store order forecasts are accumulated to generate a distribution center demand forecast; which is compared with current and projected inventory levels for the product at the distribution center to determine distribution center order quantities necessary for maintaining a product inventory level sufficient to meet the distribution center demand forecast for the product.
摘要:
A computer platform (100) uses a tamper-proof component (120), or “trusted module”, of a computer platform in conjunction with software, preferably running within the tamper-proof component, that controls the uploading and usage of data on the platform as a generic dongle for that platform. Licensing checks can occur within a trusted environment (in other words, an environment which can be trusted to behave as the user expects); this can be enforced by integrity checking of the uploading and license-checking software. Metering records can be stored in the tamper-proof device and reported back to administrators as required. There can be an associated clearinghouse mechanism to enable registration and payment for data.
摘要:
A method includes receiving a funds transfer request. The request specifies a transaction amount, a destination bank account and a source payment card account. A response to the request includes initiating a payment transaction to transfer the transaction amount from the source payment card account to a payment card system settlement account that was established by a payment card system with an agent bank. The response to the request also includes issuing an instruction for the agent bank to transfer the transaction amount from the settlement account to the destination bank account.
摘要:
A funds transfer system includes a first mobile telephone operating company and a first financial institution which exchanges data communications regarding funds transfer requests with the first mobile telephone operating company. The system further includes a second mobile telephone company and a second financial institution. The system also includes a payment processing network operating company. The payment processing network operating company transfers funds from the first financial institution to the second financial institution to benefit a recipient who owns a mobile telephone served by the second mobile telephone operating company.