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公开(公告)号：US20110165198A1
公开(公告)日：2011-07-07
申请号：US12736787
申请日：2009-05-15
申请人： Delphine Tissot-Favre , Frederic Destaillats , Yuanlong Pan , Fabiola Dionisi , Cristina Cruz-Hernandez , Clementine Thabuis , Jean-Charles Martin
发明人： Delphine Tissot-Favre , Frederic Destaillats , Yuanlong Pan , Fabiola Dionisi , Cristina Cruz-Hernandez , Clementine Thabuis , Jean-Charles Martin
IPC分类号： A61K9/00 , A61K31/16 , C07C233/20 , C07C233/09 , A61P3/06 , A61P1/14 , A61P3/00 , A61K35/66 , G09B23/28
CPC分类号： A61K31/164 , A23K10/18 , A23K20/105 , A23K50/40 , A23L33/115 , A23V2002/00 , A61K31/44 , A61K45/06 , A61K2300/00 , A23V2200/332 , A23V2250/186
摘要： The invention provides methods for using fatty acid alkanolamides for reducing lipid absorption from the intestine of an animal. Reducing lipid absorption results in fewer lipids available for an animal to convert to body fat. Converting fewer lipids to body fat means that the animal reduces body fat, body weight, and/or body weight gain when consuming an equivalent amount of lipids without the fatty acid alkanolamides.
摘要翻译： 本发明提供了使用脂肪酸链烷醇酰胺来减少动物肠内脂质吸收的方法。 减少脂质吸收导致较少的脂质可用于动物转化为身体脂肪。 将更少的脂质转化为身体脂肪意味着当消耗等量的没有脂肪酸链烷醇酰胺的脂质时，动物减少体脂肪，体重和/或体重增加。
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2.发明授权Compositions and methods for influencing satiety, lipid metabolism, and fat utilization 失效影响饱腹感，脂质代谢和脂肪利用的组成和方法公开(公告)号：US08742082B2
公开(公告)日：2014-06-03
申请号：US12737744
申请日：2009-08-10
CPC分类号： C12Q1/6883 , A61K31/20 , C12Q2600/136 , C12Q2600/158 , A61K2300/00
摘要： The invention provides (1) genes differentially expressed in animals administered fatty acid amides that affect one or more of food intake, satiety, lipid metabolism, and fat utilization and (2) compositions and methods relating to the use of the genes to identify new compounds that affect one or more of food intake, satiety, lipid metabolism, and fat utilization.
摘要翻译： 本发明提供了（1）在施用脂肪酸酰胺的动物中差异表达的基因，所述脂肪酸酰胺影响食物摄取，饱腹感，脂质代谢和脂肪利用中的一种或多种，以及（2）与使用该基因鉴定新化合物有关的组合物和方法 影响食物摄入，饱腹感，脂质代谢和脂肪利用的一种或多种。
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3.发明申请COMPOSITIONS AND METHODS FOR INFLUENCING SATIETY, LIPID METABOLISM, AND FAT UTILIZATION 失效影响满意度，脂质代谢和脂肪利用的组合物和方法公开(公告)号：US20110196042A1
公开(公告)日：2011-08-11
申请号：US12737744
申请日：2009-08-10
CPC分类号： C12Q1/6883 , A61K31/20 , C12Q2600/136 , C12Q2600/158 , A61K2300/00
摘要： The invention provides (1) genes differentially expressed in animals administered fatty acid amides that affect one or more of food intake, satiety, lipid metabolism, and fat utilization and (2) compositions and methods relating to the use of the genes to identify new compounds that affect one or more of food intake, satiety, lipid metabolism, and fat utilization.
摘要翻译： 本发明提供了（1）在施用脂肪酸酰胺的动物中差异表达的基因，所述脂肪酸酰胺影响食物摄取，饱腹感，脂质代谢和脂肪利用中的一种或多种，以及（2）与使用该基因鉴定新化合物有关的组合物和方法 影响食物摄入，饱腹感，脂质代谢和脂肪利用的一种或多种。
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公开(公告)号：US20110313039A1
公开(公告)日：2011-12-22
申请号：US13254622
申请日：2010-02-24
申请人： Frederic Destaillats , Jean-Baptiste Bezelgues , Fabiola Dionisi , Cristina Cruz-Hernandez , Isabelle Masserey-Elmelegy
发明人： Frederic Destaillats , Jean-Baptiste Bezelgues , Fabiola Dionisi , Cristina Cruz-Hernandez , Isabelle Masserey-Elmelegy
IPC分类号： A61K31/225 , A61P3/00 , A61P25/28 , A61K31/08 , A61P35/00
CPC分类号： A61K31/23 , A23K20/10 , A23K50/40 , A23L33/10 , A23L33/115 , A61K31/08 , A61K31/231 , A61K45/06 , C11C3/00
摘要： The present invention relates generally to compounds such as alkylglycerol and alkoxyglycerol for use in increasing the endogenous level of plasmalogens in a mammal. In particular, these compounds are used for increasing the endogenous plasmalogen level to a level greater than the level in healthy mammals. According to the present invention such compounds are also for use in the prevention or treatment of diseases caused or affected by a decreased endogenous level of plasmalogens. A method for the manufacture of a dietary precursor for the use of the present invention is also part of the present disclosure.
摘要翻译： 本发明一般涉及诸如烷基甘油和烷氧基甘油的化合物，其用于增加哺乳动物中等离子体发生剂的内源水平。 特别地，这些化合物用于将内源性浆细胞原子水平增加至高于健康哺乳动物水平的水平。 根据本发明，这些化合物也可用于预防或治疗由降低的血浆原核细胞内源水平引起或影响的疾病。 用于制造用于本发明的饮食前体的方法也是本公开的一部分。
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公开(公告)号：US20110275600A1
公开(公告)日：2011-11-10
申请号：US13138066
申请日：2009-12-30
IPC分类号： A61K31/661 , A61K31/232 , A61P35/00 , A61P25/28 , A61P25/00 , A61K31/202 , A61P3/00
摘要： The invention provides methods for increasing endogenous plasmalogen levels in an animal by administering to the animal an endogenous plasmalogen level increasing amount of one or more long chain polyunsaturated fatty acids (LCPUFAs).
摘要翻译： 本发明提供了通过向动物施用增加量的一种或多种长链多不饱和脂肪酸（LCPUFA）的内源性浆细胞原位水平来提高动物内源性浆细胞原子水平的方法。
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公开(公告)号：US20130109753A1
公开(公告)日：2013-05-02
申请号：US13808779
申请日：2011-07-05
申请人： Bruce Bistrian , Frederic Destaillats , Cristina Cruz-Hernandez , Fabiola Dionisi , Isabelle Masserey-Elmelegy , Manuel Oliveira , Julie Celine Moulin
发明人： Bruce Bistrian , Frederic Destaillats , Cristina Cruz-Hernandez , Fabiola Dionisi , Isabelle Masserey-Elmelegy , Manuel Oliveira , Julie Celine Moulin
IPC分类号： A61K31/202
CPC分类号： A61K31/357 , A23K20/158 , A23L2/52 , A23L33/115 , A23L33/12 , A23V2002/00 , A61K31/202 , A61K31/232 , A23V2200/324 , A23V2250/187
摘要： The present invention relates generally to the field of lipids and in particular aims at improving lipid absorption, for example under conditions of lipid maldigestion or malabsorption. One embodiment of the present invention relates to a composition comprising a sn-2 monoacylglycerol derivative, wherein the sn-1 and sn-3 positions are blocked by protective groups. The acyl group may be a fatty acid, for example one with anti-inflammatory properties.
摘要翻译： 本发明一般涉及脂质领域，特别涉及改善脂质吸收，例如在脂质消化不良或吸收不良的条件下。 本发明的一个实施方案涉及包含Sn-2单酰基甘油衍生物的组合物，其中sn-1和sn-3位置被保护基团封闭。 酰基可以是脂肪酸，例如具有抗炎性质的脂肪酸。
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公开(公告)号：US09000039B2
公开(公告)日：2015-04-07
申请号：US14009981
申请日：2012-04-03
申请人： Frederic Destaillats , Cristina Cruz-Hernandez , Fabiola Dionisi , Isabelle Masserey-Elmelegy , Manuel Oliveira , Julie Moulin
发明人： Frederic Destaillats , Cristina Cruz-Hernandez , Fabiola Dionisi , Isabelle Masserey-Elmelegy , Manuel Oliveira , Julie Moulin
IPC分类号： A61K31/22 , A23L1/30 , A61K31/23 , A61K31/231 , A61K31/232 , A61K31/25 , A61K45/06
CPC分类号： A61K31/232 , A23L33/12 , A61K31/23 , A61K31/231 , A61K31/25 , A61K45/06
摘要： The present invention relates generally to the field of lipids and in particular aims at improving lipid absorption, for example under conditions of lipid maldigestion or malabsorption. One embodiment of the present invention relates to a composition comprising sn-1(3) monoacylglycerols, wherein the sn-1 or sn-3 position is occupied by an acyl group such as a fatty acid and the sn-2 position remains unoccupied. The fatty acid may be one with anti-inflammatory properties.
摘要翻译： 本发明一般涉及脂质领域，特别涉及改善脂质吸收，例如在脂质消化不良或吸收不良的条件下。 本发明的一个实施方案涉及包含sn-1（3）单酰基甘油的组合物，其中sn-1或sn-3位置被酰基例如脂肪酸占据，并且sn-2位置保持未被占据。 脂肪酸可以是具有抗炎性质的脂肪酸。
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公开(公告)号：US20140031426A1
公开(公告)日：2014-01-30
申请号：US14009981
申请日：2012-04-03
申请人： Frederic Destaillats , Cristina Cruz-Hernandez , Fabiola Dionisi , Isabelle Masserey-Elmelegy , Manuel Oliveira , Julie Moulin
发明人： Frederic Destaillats , Cristina Cruz-Hernandez , Fabiola Dionisi , Isabelle Masserey-Elmelegy , Manuel Oliveira , Julie Moulin
IPC分类号： A61K31/232
CPC分类号： A61K31/232 , A23L33/12 , A61K31/23 , A61K31/231 , A61K31/25 , A61K45/06
摘要： The present invention relates generally to the field of lipids and in particular aims at improving lipid absorption, for example under conditions of lipid maldigestion or malabsorption. One embodiment of the present invention relates to a composition comprising sn-1(3) monoacylglycerols, wherein the sn-1 or sn-3 position is occupied by an acyl group such as a fatty acid and the sn-2 position remains unoccupied. The fatty acid may be one with anti-inflammatory properties.
摘要翻译： 本发明一般涉及脂质领域，特别涉及改善脂质吸收，例如在脂质消化不良或吸收不良的条件下。 本发明的一个实施方案涉及包含sn-1（3）单酰基甘油的组合物，其中sn-1或sn-3位置被酰基例如脂肪酸占据，并且sn-2位置保持未被占据。 脂肪酸可以是具有抗炎性质的脂肪酸。
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公开(公告)号：US20140018559A1
公开(公告)日：2014-01-16
申请号：US14007239
申请日：2012-03-23
申请人： Kornel Nagy , Komel Nagy , Frederic Destaillats , Brian Craft
发明人： Kornel Nagy , Komel Nagy , Frederic Destaillats , Brian Craft
IPC分类号： C11B3/00
摘要： The present invention generally relates to the field of refined oils. In particular, the present invention relates to refined plant oils substantially free of chlorinated contaminants, such as monochloropropanediol (MCPD), in particular 3-MCPD diesters, and to a process to produce such oils. To achieve this, plant material is washed to remove chlorine donors before a crude oil is produced that subsequently is further refined.
摘要翻译： 本发明一般涉及精炼油领域。 特别地，本发明涉及基本上不含氯化污染物的精制植物油，例如单氯丙二醇（MCPD），特别是3-MCPD二酯，以及生产这种油的方法。 为了实现这一点，在生产原油之前，将植物材料洗涤以除去氯供体，随后进一步精制。
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10.发明申请NUTRITIONAL COMPOSITION FOR SUPPORTING BRAIN DEVELOPMENT AND FUNCTION OF TODDLERS 审中-公开用于支持脑发育和功能功能的营养组合物公开(公告)号：US20120171177A1
公开(公告)日：2012-07-05
申请号：US13375079
申请日：2010-06-01
申请人： Jan Biehl , Frederic Destaillats , Laurent Fay , Yoichi Fukushima , Johannes Schmitt , Bing Wang
发明人： Jan Biehl , Frederic Destaillats , Laurent Fay , Yoichi Fukushima , Johannes Schmitt , Bing Wang
CPC分类号： A23L33/135 , A23L33/12 , A23L33/40 , A23V2002/00 , A23V2250/1868 , A23V2250/1862 , A23V2200/3204 , A23V2200/3202 , A23V2200/322
摘要： The present invention relates to a nutritional composition, in particular directed to toddlers and/or a weaning child, said nutritional composition comprising a protein source, a source of available carbohydrates, a lipid source, at least one probiotic microorganism, and prebiotics, wherein said lipid source comprises DHA (docosahexaenoic acid). The nutritional composition improves cognitive performance, in particular learning and memory of the child. Preferably, the composition comprises iron, zinc, vitamin D and/or sialic acid. Preferably, the composition comprises a source of phospholipids rich in DHA.
摘要翻译： 本发明涉及营养组合物，特别是针对幼儿和/或断奶小孩，所述营养组合物包含蛋白质源，可用碳水化合物源，脂质源，至少一种益生菌微生物和益生元，其中所述 脂质源包括DHA（二十二碳六烯酸）。 营养成分提高认知表现，特别是儿童的学习和记忆能力。 优选地，组合物包含铁，锌，维生素D和/或唾液酸。 优选地，组合物包含富含DHA的磷脂源。
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