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公开(公告)号:US20100222396A1
公开(公告)日:2010-09-02
申请号:US12695462
申请日:2010-01-28
申请人: Dirk BEHNKE , Claudia Betschart , Simona Cotesta , Marc Gerspacher , Samuel Hintermann , Bernard Lucien Roy , Anette Von Matt , Jürgen Wagner
发明人: Dirk BEHNKE , Claudia Betschart , Simona Cotesta , Marc Gerspacher , Samuel Hintermann , Bernard Lucien Roy , Anette Von Matt , Jürgen Wagner
IPC分类号: A61K31/44 , C07D207/30 , A61K31/40 , C07D213/81
CPC分类号: C07C233/78 , C07D207/416 , C07D209/08 , C07D213/81 , C07D215/48 , C07D215/50 , C07D217/26 , C07D233/66 , C07D235/24 , C07D277/56 , C07D307/79 , C07D317/68 , C07D401/12 , C07D403/12 , C07D405/12 , C07D413/12 , C07D417/12 , C07D513/04
摘要: The invention relates to compound of the formula I in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.
摘要翻译: 本发明涉及式I化合物,其中取代基如说明书中所定义; 以游离形式或盐形式; 作为其制备,用作药物和包含它的药物。
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公开(公告)号:US20120264748A1
公开(公告)日:2012-10-18
申请号:US13517111
申请日:2010-12-20
申请人: Sangamesh Badiger , Dirk Behnke , Claudia Betschart , Vinod Chaudhari , Simona Cotesta , Jürgen Hans-Hermann Hinrichs , Silvio Ofner , Chetan Pandit , Jürgen Wagner
发明人: Sangamesh Badiger , Dirk Behnke , Claudia Betschart , Vinod Chaudhari , Simona Cotesta , Jürgen Hans-Hermann Hinrichs , Silvio Ofner , Chetan Pandit , Jürgen Wagner
IPC分类号: C07D471/10 , A61K31/438 , A61K31/506 , A61K31/5377 , A61P3/00 , A61K31/5025 , A61P25/00 , A61P25/30 , A61P25/28 , A61K31/502 , A61K31/538
CPC分类号: C07D471/10
摘要: The invention relates to compound of the formula (I), in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.
摘要翻译: 本发明涉及式(I)化合物,其中取代基如说明书中所定义; 以游离形式或盐形式; 作为其制备,用作药物和包含它的药物。
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公开(公告)号:US08530648B2
公开(公告)日:2013-09-10
申请号:US13517111
申请日:2010-12-20
申请人: Sangamesh Badiger , Dirk Behnke , Claudia Betschart , Vinod Chaudhari , Simona Cotesta , Jürgen Hans-Hermann Hinrichs , Silvio Ofner , Chetan Pandit , Jürgen Wagner
发明人: Sangamesh Badiger , Dirk Behnke , Claudia Betschart , Vinod Chaudhari , Simona Cotesta , Jürgen Hans-Hermann Hinrichs , Silvio Ofner , Chetan Pandit , Jürgen Wagner
IPC分类号: C07D471/10 , A61P3/00 , A61P25/00 , A61P25/28 , A61P25/30
CPC分类号: C07D471/10
摘要: The invention relates to compound of the formula (I), in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.
摘要翻译: 本发明涉及式(I)化合物,其中取代基如说明书中所定义; 以游离形式或盐形式; 作为其制备,用作药物和包含它的药物。
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公开(公告)号:US20100179175A1
公开(公告)日:2010-07-15
申请号:US12377165
申请日:2007-08-21
申请人: Jeremy M. Sivak , Jürgen Wagner
发明人: Jeremy M. Sivak , Jürgen Wagner
IPC分类号: A61K31/517 , A61K31/438 , A61P27/02
CPC分类号: A61K31/454 , A61K31/4545 , A61K31/499 , A61K31/517 , A61K45/06 , A61K2300/00
摘要: The present invention pertains to the use of a PKC inhibitor in the treatment of an ocular disorder.
摘要翻译: 本发明涉及PKC抑制剂在眼部疾病的治疗中的应用。
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公开(公告)号:US07691861B2
公开(公告)日:2010-04-06
申请号:US10586420
申请日:2005-01-19
IPC分类号: A61K31/497 , A61K31/4025 , C07D403/14
CPC分类号: C07D401/14 , C07D403/04 , C07D403/14
摘要: A compound of formula I wherein R, Ra, Rb, Rc, Rd and Re are as defined in the specification, processes for their production, their uses, in particular in transplantation, and pharmaceutical compositions containing them.
摘要翻译: 其中R,Ra,Rb,Rc,Rd和Re如说明书中所定义的式I化合物,其制备方法,用途,特别是在移植中,以及含有它们的药物组合物。
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公开(公告)号:USD606017S1
公开(公告)日:2009-12-15
申请号:US29277307
申请日:2007-02-21
申请人: Simon Charlson , Lyndon Shenton , Jürgen Wagner
设计人: Simon Charlson , Lyndon Shenton , Jürgen Wagner
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公开(公告)号:US06918543B2
公开(公告)日:2005-07-19
申请号:US10613869
申请日:2003-07-05
申请人: Patric Schlecht , Jürgen Wagner
发明人: Patric Schlecht , Jürgen Wagner
CPC分类号: B60H1/2206 , B60H2001/224 , B60H2001/2253 , B60H2001/2265
摘要: A heating system for a vehicle comprises a heating air fan for producing a heating air flow to be introduced into a vehicle interior, a heating device with a heat exchanger arrangement for heating the heating air flow delivered by the heating air fan, a vehicle interior temperature sensor arrangement for producing an output in connection with the temperature in the vehicle interior, a vehicle interior reference temperature presetting arrangement, a heating air flow temperature sensor arrangement for producing a second output in connection with the outlet temperature of the heating air flow heated by the heating device, and also a control device which is arranged so as to set the delivery capacity of the heating air fan in dependence on the first output and on the vehicle interior reference temperature predetermined by the vehicle interior reference temperature presetting arrangement, and to set the heating capacity of the heating device in dependence on the second output.
摘要翻译: 一种用于车辆的加热系统,包括用于产生被引入车辆内部的加热空气流的加热空气风扇,具有用于加热由加热风扇输送的加热空气流的热交换器装置的加热装置,车辆内部温度 用于产生与车辆内部的温度有关的输出的传感器装置,车辆内部参考温度预设装置,用于产生第二输出的加热空气流温度传感器装置,该第二输出与加热的空气流的出口温度相关联 加热装置,以及控制装置,其被配置为根据第一输出和由车辆内部基准温度预设装置预先确定的车辆内部基准温度来设定加热风扇的输送能力,并且将 加热装置的加热能力依赖于第二输出。
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公开(公告)号:US20100273774A1
公开(公告)日:2010-10-28
申请号:US12833462
申请日:2010-07-09
IPC分类号: A61K31/553 , C07D403/04 , A61K31/404 , C07D403/14 , A61K31/496 , C07D471/04 , A61K31/437 , C07D401/14 , A61K31/4709 , A61K31/498 , A61P29/00 , A61P37/06 , A61P37/02 , A61P35/00 , C07D498/06
CPC分类号: C07D471/04 , C07D403/04 , C07D403/14
摘要: A compound of formula (I), wherein R, R1, R2, ring A, which ring contains one or two nitrogen atoms, and ring B are as defined in the Specification, pharmaceutical compositions containing these compounds, and uses for these compounds and compositions, in particular, in transplantation.
摘要翻译: 式(I)的化合物,其中R 1,R 2,R 2,环A,其中含有一个或两个氮原子的环A和环B如本说明书中所定义,含有这些化合物的药物组合物,以及这些化合物和组合物的用途 ,特别是在移植中。
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公开(公告)号:US07781438B2
公开(公告)日:2010-08-24
申请号:US11995450
申请日:2006-07-10
IPC分类号: A61K31/4965 , A61K31/40 , A01N43/52 , A01N43/56 , C07D401/00
CPC分类号: C07D471/04 , C07D403/04 , C07D403/14
摘要: A compound of formula (I) wherein R, R1, and R2, ring A and ring B are as defined in the specification, processes for their production, their uses, in particular in transplantation, and pharmaceutical compositions containing them.
摘要翻译: 式(I)的化合物,其中R,R 1和R 2,环A和环B如说明书中所定义,其制备方法,其用途,特别是在移植中,以及含有它们的药物组合物。
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公开(公告)号:US20100176601A1
公开(公告)日:2010-07-15
申请号:US12602224
申请日:2008-06-03
CPC分类号: F16C17/10 , F03D80/70 , F05B2260/90 , F05B2260/902 , F05B2280/501 , F05C2251/14 , F16C41/001 , F16C2300/14 , Y02E10/722
摘要: The invention relates to a bearing arrangement, especially for a wind turbine, for transmitting radial and axial forces, two bearing partners being provided that are twistable relative to one another about an axis. The bearing partners each comprise a support area, between which a bearing block is arranged to be insertable in an actuating direction in order to generate a normal force that acts upon the support areas. The bearing block is connected in a rotationally fixed manner to one of the bearing partners. The aim of the invention is to design an improved bearing arrangement which overcomes the drawbacks of the prior art. In particular, the aim is to design a wear-resistant and maintenance-friendly bearing arrangement for an azimuth bearing of a windturbine. Furthermore, an optional aim of the invention is to make it possible to simultaneously use the bearing arrangement as an active brake. Said aim is achieved by the features of independent claim 1, according to which a friction lining is disposed between the bearing block and the bearing partner that can be twisted relative to the bearing block. For the first time, this design makes it possible to represent a support of a bearing ring and a bearing rim, the bearing clearance being easy to adjust.
摘要翻译: 本发明涉及一种用于传递径向和轴向力的特别用于风力涡轮机的轴承装置,提供了相对于彼此围绕轴线可扭转的两个轴承配合件。 轴承配件每个都包括支撑区域,在该支撑区域之间,轴承座布置成可沿致动方向插入,以便产生作用在支撑区域上的法向力。 轴承座以旋转固定的方式连接到轴承配件之一。 本发明的目的是设计一种克服现有技术的缺点的改进的轴承装置。 特别地,其目的是为风力发电机的方位角轴承设计耐磨和维护方便的轴承装置。 此外,本发明的可选目的是使得可以同时使用轴承装置作为主动制动器。 所述目的通过独立权利要求1的特征来实现,根据该特征,摩擦衬里设置在可相对于轴承座扭转的轴承座和轴承座之间。 第一次,这种设计使得可以表示轴承圈和轴承轮圈的支撑,轴承间隙容易调整。
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