公开(公告)号：US07935345B2

公开(公告)日：2011-05-03

申请号：US12123339

申请日：2008-05-19

申请人： Donald Reason ,  Jianhui Zhou

发明人： Donald Reason ,  Jianhui Zhou

IPC分类号： A61K39/40 ,  C07K16/00

CPC分类号： C40B40/10 ,  C07K16/1278 ,  C07K2317/21 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/76 ,  C40B30/04 ,  C40B50/06 ,  G01N2333/32

摘要： The invention features compositions relating to antibodies that specifically bind to the protective antigen of Bacillus anthracis, fragments thereof, and nucleic acids encoding same. The invention further features methods of using such compositions.

摘要翻译： 本发明涉及与特异性结合炭疽芽孢杆菌的保护性抗原的抗体相关的组合物，其片段和编码其的核酸。 本发明还涉及使用这种组合物的方法。

公开(公告)号：US20160168841A1

公开(公告)日：2016-06-16

申请号：US15049076

申请日：2016-02-20

申请人： Jianhui Zhou

发明人： Jianhui Zhou ,  Dingming Zhou

IPC分类号： E04B1/19

CPC分类号： E04B1/1903 ,  E04B1/585 ,  E04B2001/1957 ,  E04C3/08 ,  E04C2003/0491 ,  E04G1/06 ,  E04G7/14 ,  E04H12/085 ,  E04H12/10 ,  E04H2012/006

摘要： A combined member, comprising a communication rod (1) and a connecting rod (2), wherein the connecting rod (2) comprises a rod body (2.1) and a connector (2.2), the connector (2.2) being a fastening connector (3) or a sleeving connector (4), the rod body (2.1) of the connecting rod (2.1) and a rod body of the communication rod (1) being of a strip-shaped structure, the connecting rod (2) being connected to the communication rod (1) by the fastening connector (3) or the sleeving connector (4), the axis of the connecting rod (2) intersecting that of the communication rod (1) connected thereto. The combined member has the advantages of high bearing capacity, and convenient construction.

摘要翻译： 一种组合构件，包括通信杆（1）和连杆（2），其中所述连杆（2）包括杆体（2.1）和连接器（2.2），所述连接器（2.2）是紧固连接器 3）或套筒连接器（4），连杆（2.1）的杆体（2.1）和连杆（1）的杆体是条形结构，连杆（2）连接 通过紧固连接器（3）或套筒连接器（4）与连杆（1）连接，连杆（2）的轴线与与其连接的连杆（1）的轴线相交。 组合件具有承载力高，施工方便的优点。

公开(公告)号：US08969489B2

公开(公告)日：2015-03-03

申请号：US13205152

申请日：2011-08-08

申请人： Jianhui Zhou ,  Angela Jones Johnson

发明人： Jianhui Zhou ,  Angela Jones Johnson

IPC分类号： C09D169/00 ,  C08G64/02 ,  H01S3/097 ,  C08G64/30 ,  C08K5/29 ,  C08K5/3492

CPC分类号： H01S3/097 ,  C08G64/0208 ,  C08G64/305 ,  C08K5/29 ,  C08K5/34922 ,  C08K5/34924 ,  C09D169/00

摘要： The invention is a thermosetting coating composition comprised of an aliphatic polycarbonate resin and a cross linker. The aliphatic polycarbonate resins are derived from hydroxyl containing compounds including 2,2,4,4-tetramethyl-1,3-cyclobutanediol (TMCD) and 1,4-cyclohexane dimethanol (CHDM). The coatings made of these polycarbonates exhibit exceptional toughness; they possess a high degree of hardness while maintaining a high level of flexibility/impact resistance. These polycarbonate resins also exhibited better hydrolytic stability as compared to their polyester counterparts.

摘要翻译： 本发明是由脂族聚碳酸酯树脂和交联剂组成的热固性涂料组合物。 脂肪族聚碳酸酯树脂衍生自包含2,2,4,4-四甲基-1,3-环丁二醇（TMCD）和1,4-环己烷二甲醇（CHDM）的含羟基化合物。 由这些聚碳酸酯制成的涂层表现出优异的韧性; 它们具有高度的硬度，同时保持高水平的柔韧性/抗冲击性。 与聚酯树脂相比，这些聚碳酸酯树脂也表现出更好的水解稳定性。

公开(公告)号：US06509987B1

公开(公告)日：2003-01-21

申请号：US09371165

申请日：1999-08-10

申请人： Guido H. Hunziker ,  Stan Lumish ,  Jianhui Zhou

发明人： Guido H. Hunziker ,  Stan Lumish ,  Jianhui Zhou

IPC分类号： H04J1402

CPC分类号： H04B10/291 ,  G02F1/353 ,  G02F1/3536 ,  H04J14/0201 ,  H04J14/0213

摘要： The number of optical channels that may be used to transmit information/data is greatly enhanced using an optical transmission facility having a transmitter that outputs optical signals having respective wavelengths within a first bandwidth, e.g., the C band, combines the latter signal with an optical signal having a wavelength between the first bandwidth and a second bandwidth, e.g., the L-band, and, using a non-linear frequency converter, processes the combined signal to form at least optical signals having wavelengths within the second bandwidth that correspond with the wavelengths of the optical signals within the first bandwidth. In this way, equipment designed for the C band may also be used to process optical signals with another, second band.

摘要翻译： 使用具有输出具有第一带宽内的各个波长的光信号的发射机的光传输设备，例如C波段，将后一信号与光信号相结合，可以大大增强可用于传输信息/数据的光信道数量 具有第一带宽和第二带宽之间的波长的信号，例如L波段，并且使用非线性频率转换器处理组合信号，以至少形成具有与第二带宽内的波长相对应的波长的光信号 在第一带宽内的光信号的波长。 以这种方式，为C频带设计的设备也可以用于处理具有另一个第二频带的光信号。

公开(公告)号：US07973143B2

公开(公告)日：2011-07-05

申请号：US12341520

申请日：2008-12-22

申请人： Julie D. Saba ,  Jianhui Zhou

发明人： Julie D. Saba ,  Jianhui Zhou

IPC分类号： C07K16/40 ,  C07K16/00 ,  G01N33/573

CPC分类号： C12Q1/6886 ,  A01K2217/05 ,  A01K2217/075 ,  C12N9/88 ,  C12Q2600/136 ,  Y10S435/81 ,  Y10S435/975

摘要： Compositions, methods and kits for diagnosing and treating cancer are provided. Therapeutic compositions may comprise agents that modulate the expression or activity of a sphingosine-1-phosphate lyase (SPL). Such compositions may be administered to a mammal afflicted with cancer. Diagnostic methods and kits may employ an agent suitable for detecting alterations in endogenous SPL. Such methods and kits may be used to detect the presence of a cancer or to evaluate the prognosis of a known disease. SPL polypeptides, polynucleotides and antibodies are also provided.

摘要翻译： 提供用于诊断和治疗癌症的组合物，方法和试剂盒。 治疗组合物可以包含调节鞘氨醇-1-磷酸裂解酶（SPL）的表达或活性的试剂。 这种组合物可以施用于患有癌症的哺乳动物。 诊断方法和试剂盒可以使用适合于检测内源性SPL变化的试剂。 这些方法和试剂盒可用于检测癌症的存在或评价已知疾病的预后。 还提供了SPL多肽，多核苷酸和抗体。

公开(公告)号：US07933518B2

公开(公告)日：2011-04-26

申请号：US12035327

申请日：2008-02-21

申请人： Wen Li ,  Jianhui Zhou ,  Wen Huang ,  Fulin Pan

发明人： Wen Li ,  Jianhui Zhou ,  Wen Huang ,  Fulin Pan

IPC分类号： H04B10/08

CPC分类号： H04B10/40

摘要： An integrated optical transceiver includes an optical receiver that produces a first electrical signal at a reception electrical interface in response to a first optical signal, an optical transmitter that emits a second optical signal in response to a second electrical signal received at a transmission electrical interface, a first optical branching device that receives the first optical signal at an reception optical interface and to direct at least a portion of the first optical signal to the optical receiver, and a second optical branching device that directs the second optical signal to an transmission optical interface. The first optical branching device directs at least a portion of the first optical signal to the second optical branching device. The second optical branching device directs the portion of the first optical signal received from the first optical branching device to the transmission optical interface.

摘要翻译： 集成光收发器包括：光接收器，其响应于第一光信号在接收电接口处产生第一电信号;响应于在传输电接口接收的第二电信号发射第二光信号的光发射机， 第一光分支装置，其在接收光接口处接收所述第一光信号并将所述第一光信号的至少一部分引导到所述光接收器;以及第二光分支装置，其将所述第二光信号引导到透射光接口 。 第一光分路装置将第一光信号的至少一部分引导到第二光分支装置。 第二光分支装置将从第一光分支装置接收的第一光信号的部分引导到传输光接口。

公开(公告)号：US20100215359A1

公开(公告)日：2010-08-26

申请号：US12390484

申请日：2009-02-22

申请人： Wen Li ,  Fulin Pan ,  Jianhui Zhou

发明人： Wen Li ,  Fulin Pan ,  Jianhui Zhou

IPC分类号： H04B10/08 ,  H04B10/06 ,  H04B10/00

CPC分类号： H04B10/40

摘要： An optical transceiver includes an electric terminal that can receive power from a host equipment and provide a power supply voltage to the optical transceiver, and a power failure monitor circuit that can detect an imminent loss of the power supply voltage. The power failure monitor circuit can produce a dying-gasp control signal when such imminent loss of power supply voltage is detected or when a disabling control signal is received from the host equipment. A driver can receive the dying-gasp control signal. An optical transmitter is powered by the power supply voltage and can emit a first optical signal under the control of the driver. The driver can modulate an envelope of the first optical signal in response to the dying-gasp control signal to produce a modulated envelope comprising a first dying gasp signal.

摘要翻译： 光收发器包括能够从主机设备接收电力并向光收发器提供电源电压的电端子，以及能够检测即将发生的电源电压损失的电源故障监视电路。 当检测到电源电压即将发生或当从主机设备接收到禁用控制信号时，电源故障监控电路可以产生一个垂死的喘气控制信号。 驾驶员可以接收垂直喘气控制信号。 光发射机由电源电压供电，并可在驱动器的控制下发出第一光信号。 驱动器可以响应于垂直气体控制信号来调制第一光信号的包络，以产生包括第一垂直气体信号的调制包络。

公开(公告)号：US20090203044A1

公开(公告)日：2009-08-13

申请号：US12341520

申请日：2008-12-22

申请人： Julie D. Saba ,  Jianhui Zhou

发明人： Julie D. Saba ,  Jianhui Zhou

IPC分类号： G01N33/573 ,  C07K16/18

CPC分类号： C12Q1/6886 ,  A01K2217/05 ,  A01K2217/075 ,  C12N9/88 ,  C12Q2600/136 ,  Y10S435/81 ,  Y10S435/975

摘要： Compositions, methods and kits for diagnosing and treating cancer are provided. Therapeutic compositions may comprise agents that modulate the expression or activity of a sphingosine-1-phosphate lyase (SPL). Such compositions may be administered to a mammal afflicted with cancer. Diagnostic methods and kits may employ an agent suitable for detecting alterations in endogenous SPL. Such methods and kits may be used to detect the presence of a cancer or to evaluate the prognosis of a known disease. SPL polypeptides, polynucleotides and antibodies are also provided.

摘要翻译： 提供用于诊断和治疗癌症的组合物，方法和试剂盒。 治疗组合物可以包含调节鞘氨醇-1-磷酸裂解酶（SPL）的表达或活性的试剂。 这种组合物可以施用于患有癌症的哺乳动物。 诊断方法和试剂盒可以使用适合于检测内源性SPL变化的试剂。 这些方法和试剂盒可用于检测癌症的存在或评价已知疾病的预后。 还提供了SPL多肽，多核苷酸和抗体。

公开(公告)号：US06423527B1

公开(公告)日：2002-07-23

申请号：US08939309

申请日：1997-09-29

申请人： Julie D. Saba ,  Jianhui Zhou

发明人： Julie D. Saba ,  Jianhui Zhou

IPC分类号： C12N988

CPC分类号： C12Q1/6886 ,  A01K2217/05 ,  A01K2217/075 ,  C12N9/88 ,  C12Q2600/136 ,  Y10S435/81 ,  Y10S435/975

摘要： Compositions, methods and kits for diagnosing and treating cancer are provided. Therapeutic compositions may comprise agents that modulate the expression or activity of a springiness-1-phosphate lease (SPL). Such compositions may be administered to a mammal afflicted with cancer. Diagnostic methods and kits may employ an agent suitable for detecting alterations in endogenous SPL. Such methods and kits may be used to detect the presence of a cancer or to evaluate the prognosis of a known disease. SPL polypeptides, polynucleotides and antibodies are also provided.

摘要翻译： 提供用于诊断和治疗癌症的组合物，方法和试剂盒。 治疗组合物可以包含调节弹性-1-磷酸盐（SPL）的表达或活性的试剂。 这种组合物可以施用于患有癌症的哺乳动物。 诊断方法和试剂盒可以使用适合于检测内源性SPL变化的试剂。 这些方法和试剂盒可用于检测癌症的存在或评价已知疾病的预后。 还提供了SPL多肽，多核苷酸和抗体。

公开(公告)号：US06366393B1

公开(公告)日：2002-04-02

申请号：US09382853

申请日：1999-08-25

申请人： Matthias Richard Feulner ,  Guido Hermann Hunziker ,  Bernd Teichmann ,  Dieter Werner ,  Jianhui Zhou

发明人： Matthias Richard Feulner ,  Guido Hermann Hunziker ,  Bernd Teichmann ,  Dieter Werner ,  Jianhui Zhou

IPC分类号： H01S300

CPC分类号： H04B10/2942 ,  H01S3/10015 ,  H01S3/1301

摘要： In an optically amplified wavelength division multiplexed (WDM) system having a WDM signal comprising a plurality of optical channels, the per-channel gain of the optical channels is kept relatively constant despite changes in input power at the optical amplifier, such as when individual optical channels of the WDM signal are added and dropped. More specifically, gain of an optical amplifier is controlled by controlling the amount of pump power supplied to the optical amplifier as a function of changes in input power which are measured in a feed-forward monitoring path. The amount of pump power for effecting gain control is adjusted according to a scaled relationship to the measured input power of the optical amplifier. By controlling the pump power directly in response to changes in input power, gain of the optical amplifier can be controlled within a sub-microsecond time scale from the time that a change in input power is detected. Moreover, by maintaining relatively constant per-channel gain in an amplified WDM signal despite changes in input power at the optical amplifier, power excursions are substantially reduced in surviving optical channels of the WDM signal, i.e., those at the output of the optical amplifier.

摘要翻译： 在具有包括多个光通道的WDM信号的光学放大波分多路复用（WDM）系统中，尽管光放大器的输入功率发生变化，但是光通道的每通道增益保持相对恒定，例如当单个光 WDM信号的信道被添加和丢弃。 更具体地，通过根据在前馈监视路径中测量的输入功率的变化来控制提供给光放大器的泵浦功率的量来控制光放大器的增益。 根据与光放大器的测量输入功率的比例关系来调节用于实现增益控制的泵浦功率量。 通过响应于输入功率的变化直接控制泵浦功率，从检测到输入功率的变化的时刻起，可以将光放大器的增益控制在亚微秒级。 此外，尽管在光放大器的输入功率发生变化，通过保持放大的WDM信号中的每通道增益相对恒定的增益，但WDM信号的存储光通道（即光放大器的输出端）的功率偏移大大降低。