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    COMBINED CGH & ALLELE SPECIFIC HYBRIDISATION METHOD
    1.
    发明申请
    COMBINED CGH & ALLELE SPECIFIC HYBRIDISATION METHOD 有权
    组合CGH和ALLELE特异性混合方法

    公开(公告)号：US20130102476A1

    公开(公告)日：2013-04-25

    申请号：US13520935

    申请日：2011-01-07

    申请人： Douglas Hurd ,  Edwin Southern ,  Richard Stark

    发明人： Douglas Hurd ,  Edwin Southern ,  Richard Stark

    IPC分类号： C12Q1/68

    CPC分类号： G06F19/20 ,  C12Q1/6837 ,  C12Q1/6883 ,  C12Q1/6886 ,  C12Q2600/156 ,  C12Q2600/172 ,  C12Q2525/151 ,  C12Q2535/131 ,  C12Q2537/16 ,  C12Q2539/115 ,  C12Q2565/513

    摘要： The invention combines the fields of comparative genomic hybridisation (CGH) analysis and SNP array analysis. It relates to methods for detecting and mapping genetic abnormalities associated with various diseases. In particular the invention provides a method for simultaneously performing array CGH and SNP array analysis on a genomic DNA sample comprising contacting a nucleic acid array which comprises a first probe set and a second probe set with a genomic DNA sample, comprising a test and reference sample, under hybridisation conditions, comparing the amount of test sample and reference sample hybridised to the hybridisation probes of the first probe set, comparing the amount of test sample and reference sample hybridised to the hybridisation probes of the second probe set; and using the data obtained to determine the copy number of at least one locus; and at least one SNP in the genomic DNA sample.

    摘要翻译： 本发明结合了比较基因组杂交（CGH）分析和SNP阵列分析的领域。 它涉及检测和绘制与各种疾病相关的遗传异常的方法。 特别地，本发明提供了一种用于在基因组DNA样品上同时进行阵列CGH和SNP阵列分析的方法，包括使包含第一探针组和第二探针组的核酸阵列与基因组DNA样品接触，所述核酸阵列包含测试和参考样品 在杂交条件下，比较与第一探针组的杂交探针杂交的测试样品和参考样品的量，比较与第二探针组的杂交探针杂交的测试样品和参考样品的量; 并使用获得的数据来确定至少一个轨迹的拷贝数; 和基因组DNA样品中的至少一个SNP。

    Continuously variable transmission
    2.
    发明授权
    Continuously variable transmission 有权
    连续可变传动

    公开(公告)号：US07125355B2

    公开(公告)日：2006-10-24

    申请号：US10667215

    申请日：2003-09-19

    申请人： Jens Schmidt ,  Richard Stark ,  Remi Leorat

    发明人： Jens Schmidt ,  Richard Stark ,  Remi Leorat

    IPC分类号： F16H57/04 ,  B05B1/14

    CPC分类号： F16H57/0456 ,  F16H57/0489

    摘要： A regulatable continuously variable transmission in which one multiple-jet nozzle (4) is used for supplying cooling and lubricant oil to the variator. The flow diameter (9, 10) of the nozzle (4) is created so that a stationary flow exists in the nozzle (4) and the continuity equation results in a constant value.

    摘要翻译： 一种可调节的无级变速器，其中一个多喷嘴（4）用于向变速器供应冷却和润滑油。 创建喷嘴（4）的流动直径（9,10），使得在喷嘴（4）中存在静止流，并且连续性方程得到恒定值。

    Motorcycle footrest
    3.
    发明授权
    Motorcycle footrest 有权

    公开(公告)号：US11110983B1

    公开(公告)日：2021-09-07

    申请号：US16781218

    申请日：2020-02-04

    申请人： Richard Stark

    发明人： Richard Stark

    IPC分类号： B62J25/06

    摘要： A motorcycle footrest that is configured to be operably coupled to a motorcycle and provide an additional footrest member for a rider to place their feet during operation of the motorcycle. The motorcycle footrest of the present invention includes a coupling member wherein the coupling member is undulated in shape having a contiguous upper portion and lower portion. The lower portion has an aperture formed therethrough and is of suitable size to accommodate a footpeg standoff therethrough. The coupling member includes an offset member contiguous therewith. A first arm support member is rotatably secured to the offset member and includes a first end and second end. A second arm support member is secured to the second end of the first arm support member. A footrest member is secured to the second end of the second support arm member.

    Leak detection method for testing fuel rods of fuel assemblies of a boiling water reactor for leaks
    4.
    发明授权
    Leak detection method for testing fuel rods of fuel assemblies of a boiling water reactor for leaks 有权
    用于检测沸水反应堆燃料组件燃料棒泄漏的泄漏检测方法

    公开(公告)号：US07778378B2

    公开(公告)日：2010-08-17

    申请号：US11801939

    申请日：2007-05-11

    申请人： Markus Pülmanns ,  Richard Stark

    发明人： Markus Pülmanns ,  Richard Stark

    IPC分类号： G21C17/00

    CPC分类号： G21C17/04 ,  G21C17/06 ,  G21C17/07 ,  G21Y2002/202 ,  G21Y2002/40 ,  G21Y2004/40

    摘要： Fuel rods of fuel assemblies of a boiling water reactor are tested for leaks. A plurality of fuel assemblies are each arranged adjacent to one another in a cell of the upper core grid of the boiling water reactor. A hood is placed above a plurality of cells A water sample is taken from each of the cells, and the water samples from a plurality of cells forming a group are combined and tested for the presence of radioactive fission products A plurality of groups are analyzed simultaneously in a number, which number corresponds to the number of groups, of measurement channels. Where a result of a group is positive, the cells of the group are tested separately by the measurement channels. Those fuel assemblies of a cell that is found positive are tested individually outside the hood.

    摘要翻译： 测试沸水反应堆的燃料组件的燃料棒的泄漏。 多个燃料组件各自相邻布置在沸水反应堆的上部核心格栅的电池中。 将罩放置在多个细胞上方从每个细胞中取出水样，并且组合来自形成组的多个细胞的水样品并测试放射性裂变产物的存在。同时分析多个组 在一个数字中，哪个数字对应于组的数量，测量通道。 如果组的结果为正，则通过测量通道单独测试该组的单元。 发现阳性的电池的那些燃料组件在罩外单独测试。

    Infinitely variable-speed transmission
    5.
    发明授权
    Infinitely variable-speed transmission 失效
    无级变速传动

    公开(公告)号：US6123634A

    公开(公告)日：2000-09-26

    申请号：US946534

    申请日：1997-10-07

    申请人： Hartmut Faust ,  Richard Stark

    发明人： Hartmut Faust ,  Richard Stark

    IPC分类号： F16H9/12 ,  F16H55/32 ,  F16H55/56 ,  F16H59/00 ,  F16H61/00

    CPC分类号： F16H55/56 ,  F16H55/32

    摘要： An infinitely variable-speed transmission for use in the power train of a motor vehicle has two rotary sheaves and an endless flexible element trained over the sheaves to transmit torque from the flanges of one of the sheaves to the flanges of the other sheave when the one sheave is driven by the prime mover of the vehicle. The flanges have exposed conical surfaces which are frictionally engaged by the exposed end surfaces of pintles forming part of the flexible element when the latter transmits torque. The flanges are hardened, cushioned, roughened and/or otherwise treated at their exposed surfaces to promote the ability of the sheaves to eliminate or reduce noise on contact with the pintles, to stand long periods of use without extensive wear, and/or to transmit pronounced and variable torques.

    摘要翻译： 用于机动车辆的动力传动系中的无级变速传动装置具有两个旋转滑轮和在滑轮上训练的环形柔性元件，以将扭矩从一个滑轮的凸缘传递到另一个滑轮的凸缘， 滑轮由车辆的原动机驱动。 凸缘具有暴露的圆锥形表面，当锥形表面传递扭矩时，凸出的锥形表面由露出的枢轴接合，形成一部分柔性元件。 法兰在其暴露的表面上被硬化，缓冲，粗糙化和/或以其他方式处理，以促进滑轮消除或减少与枢轴接触时的噪音的能力，以便在没有大量磨损的情况下长时间使用，和/或传送 明显的和可变的扭矩。

    Leak detection method for testing fuel rods of fuel assemblies of a boiling water reactor for leaks
    6.
    发明申请
    Leak detection method for testing fuel rods of fuel assemblies of a boiling water reactor for leaks 有权
    用于检测沸水反应堆燃料组件燃料棒泄漏的泄漏检测方法

    公开(公告)号：US20080130818A1

    公开(公告)日：2008-06-05

    申请号：US11801939

    申请日：2007-05-11

    申请人： Markus Pulmanns ,  Richard Stark

    发明人： Markus Pulmanns ,  Richard Stark

    IPC分类号： G21C17/07

    CPC分类号： G21C17/04 ,  G21C17/06 ,  G21C17/07 ,  G21Y2002/202 ,  G21Y2002/40 ,  G21Y2004/40

    摘要： Fuel rods of fuel assemblies of a boiling water reactor are tested for leaks. A plurality of fuel assemblies are each arranged adjacent to one another in a cell of the upper core grid of the boiling water reactor. A hood is placed above the fuel assemblies of a plurality of cells, which form a division for simultaneously heating the fuel assemblies of this division. At least one water sample is taken from each cell of this division, and the water samples from a plurality of cells forming a group are combined and tested for the presence of radioactive fission products contained in the water sample. A plurality of groups are analyzed simultaneously and independently of one another in a number, which number corresponds to the number of groups, of measurement channels of an analysis device. Where a result of a group is positive, the water samples from the cells which are located in this group are fed separately to the analysis device and are analyzed separately in a corresponding number of measurement channels. Those fuel assemblies of a cell that are found positive are tested individually outside the hood.

    摘要翻译： 测试沸水反应堆的燃料组件的燃料棒的泄漏。 多个燃料组件各自相邻布置在沸水反应堆的上部核心格栅的电池中。 将发动机罩放置在多个电池的燃料组件上方，形成用于同时加热该部分的燃料组件的分隔件。 从该分区的每个细胞中取出至少一个水样品，并且组合来自形成组的多个细胞的水样品，并测试水样中包含的放射性裂变产物的存在。 多个组被分析同时且彼此独立地分析，数量对应于分析装置的测量通道的组数。 当组的结果为正时，来自位于该组中的单元的水样本被单独地供给到分析装置，并在相应数量的测量通道中单独分析。 发现阳性的细胞的那些燃料组件在罩外单独测试。

    Method and apparatus for testing nuclear reactor fuel assemblies
    9.
    发明授权
    Method and apparatus for testing nuclear reactor fuel assemblies 有权

    公开(公告)号：US06570949B2

    公开(公告)日：2003-05-27

    申请号：US09994202

    申请日：2001-11-26

    申请人： Klaus Knecht ,  Richard Stark

    发明人： Klaus Knecht ,  Richard Stark

    IPC分类号： G21C1700

    CPC分类号： G21C17/07

    摘要： A method for testing whether fuel rods of fuel assemblies resting on a working base and under water, of a nuclear reactor are leaking is disclosed. The method includes heating at least one first fuel assembly of a first division of fuel assemblies for driving radioactive fission products out of a defective fuel rod contained in the first fuel assembly. The first fuel assembly is continuously tested by extracting samples of water and continuously degassing the water removed from an area around the first fuel assembly even during the heating resulting in gas. A radioactivity of gaseous fission products released in the gas is continuously recorded. A fuel assembly belonging to a second division of fuel assemblies is heated only if the first fuel assembly belonging to the first division of fuel assemblies has been tested. An apparatus for implementing the method is also disclosed.

    Toy animal life preserver
    10.
    发明授权
    Toy animal life preserver 失效
    玩具动物救生员

    公开(公告)号：US4668201A

    公开(公告)日：1987-05-26

    申请号：US728409

    申请日：1985-04-29

    申请人： Richard Stark

    发明人： Richard Stark

    IPC分类号： A63H3/02 ,  B63C9/08 ,  B63C9/10

    CPC分类号： B63C9/08 ,  A63H3/02

    摘要： A substantially indestructible, long wearing, life preserver teddy bear toy is constructed with a shaped body of foam plastic enveloped in a tough, snug fitting, water repellant, close fitting fabric outer layer so that the body absorbs less than 5% of its total weight when immersed in water and has enough buoyancy to support a child.

    摘要翻译： 一个基本上坚不可摧的长时间穿着的救生玩具玩具熊玩具被塑造成一个泡沫塑料体，它包裹着坚韧，贴合，防水，紧密的织物外层，使身体吸收的总重不到5％ 当沉浸在水中并具有足够的浮力来支撑孩子时。