COMPOSITION FOR APPLICATION TO A MUCOSA COMPRISING A METHYLCELLULOSE
    10.
    发明申请
    COMPOSITION FOR APPLICATION TO A MUCOSA COMPRISING A METHYLCELLULOSE 审中-公开
    用于包含甲基纤维素的粘蛋白的组合物

    公开(公告)号:US20160114047A1

    公开(公告)日:2016-04-28

    申请号:US14890617

    申请日:2014-07-16

    摘要: A composition designed for application to a mucosa comprises a tonicity-adjusting agent, a methylcellulose, and a liquid diluent, wherein the methylcellulose has anhydroglucose units joined by 1-4 linkages wherein hydroxy groups of anhydroglucose units are substituted with methyl groups such that s23/s26 is 0.36 or less, wherein s23 is the molar fraction of anhydroglucose units wherein only the two hydroxy groups in the 2- and 3-positions of the anhydroglucose unit are substituted with methyl groups and wherein s26 is the molar fraction of anhydroglucose units wherein only the two hydroxy groups in the 2- and 6-positions of the anhydroglucose unit are substituted with methyl groups.

    摘要翻译: 设计用于粘膜的组合物包括张力调节剂,甲基纤维素和液体稀释剂,其中甲基纤维素具有通过1-4键连接的脱水葡萄糖单元,其中脱水葡萄糖单元的羟基被甲基取代,使得s23 / s26为0.36以下,其中s23是脱水葡萄糖单元的摩尔分数,其中脱水葡萄糖单元的2-和3-位中的两个羟基仅被甲基取代,并且其中s26是脱水葡萄糖单元的摩尔分数,其中仅 脱水葡萄糖单元的2-和6-位上的两个羟基被甲基取代。