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1.发明授权Chimeric vectors comprising a phage packaging site and a portion derived from the genome of a eukaryotic virus 有权包含噬菌体包装位点和源自真核病毒基因组的部分的嵌合载体公开(公告)号：US06440728B1
公开(公告)日：2002-08-27
申请号：US09450972
申请日：1999-11-30
IPC分类号： C12N1563
CPC分类号： C12N15/86 , C12N2710/10343 , C12N2710/10344 , C12N2795/10344 , C12N2810/405 , C12N2830/002 , C12N2830/005 , C12N2830/15 , C12N2830/55
摘要： The present invention provides an improved method of making eukaryotic gene transfer vectors comprising homologous recombining lambdid vectors with a second DNA in a bacterium to generate novel recombinant eukaryotic viral gene transfer vectors as well as a novel lambdid vector used in the inventive method and an inventive system comprising the novel lambdid vector.
摘要翻译： 本发明提供了一种制备包含同源重组羊羔载体的真核基因转移载体与细菌中的第二DNA以产生新的重组真核病毒基因转移载体以及用于本发明方法和本发明系统的新型羔羊载体的改进方法 包括新的小鼠载体。
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公开(公告)号：US07070930B2
公开(公告)日：2006-07-04
申请号：US10162043
申请日：2002-06-03
CPC分类号： C12N15/86 , C12N2710/10343 , C12N2710/10344 , C12N2795/10344 , C12N2810/405 , C12N2830/002 , C12N2830/005 , C12N2830/15 , C12N2830/55
摘要： The present invention provides an improved method of making eukaryotic gene transfer vectors comprising homologous recombining lambdid vectors with a second DNA in a bacterium to generate novel recombinant eukaryotic viral gene transfer vectors as well as a novel lambdid vector used in the inventive method and an inventive system comprising the novel lambdid vector.
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3.发明申请公开(公告)号：US20070155647A1
公开(公告)日：2007-07-05
申请号：US11445375
申请日：2006-06-01
申请人： Hugo Demeyere , Karel Claeys , Mohammed Zuber , Frank Hulskotter
发明人： Hugo Demeyere , Karel Claeys , Mohammed Zuber , Frank Hulskotter
IPC分类号： C11D3/00
CPC分类号： C11D3/0015 , C11D1/62 , C11D1/645 , C11D3/2006 , C11D3/2041 , C11D3/2058 , C11D3/2068 , C11D3/43
摘要： Cationic charge boosters, wherein the booster has a single alkoxychain, provide clear or translucent compositions with improved softening performance with a lesser amount of softener active.
摘要翻译： 阳离子电荷增强剂，其中增强剂具有单个烷氧基链，提供透明或半透明组合物，其具有改善的软化性能，而较少量的软化剂活性物质。
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4.发明申请Clear or translucent liquid fabric softening compositions with improved dispersibility 审中-公开透明或半透明液体织物软化组合物具有改善的分散性公开(公告)号：US20070135331A1
公开(公告)日：2007-06-14
申请号：US11444663
申请日：2006-06-01
IPC分类号： C11D3/00
CPC分类号： C11D1/721 , C11D1/62 , C11D1/722 , C11D1/835 , C11D3/0015 , C11D3/2003 , C11D3/2048
摘要： The present invention relates to clear or translucent liquid fabric softening compositions. The composition of the invention comprises a fabric softener, a principal solvent and a non-ionic surfactant.
摘要翻译： 本发明涉及透明或半透明液体织物软化组合物。 本发明的组合物包括织物柔软剂，主要溶剂和非离子表面活性剂。
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公开(公告)号：US20060286121A1
公开(公告)日：2006-12-21
申请号：US11337866
申请日：2006-01-23
申请人： Jason Gall , Thomas Wickham , William Enright , Douglas Brough , Mohammed Zuber , C. King , Gary Nabel , Cheng Cheng
发明人： Jason Gall , Thomas Wickham , William Enright , Douglas Brough , Mohammed Zuber , C. King , Gary Nabel , Cheng Cheng
IPC分类号： A61K39/12 , A61K39/395
CPC分类号： C12N15/86 , A61K48/00 , A61K2039/5256 , C07K2319/00 , C12N2710/10343 , C12N2710/10345
摘要： The invention provides a method of inducing an immune response in a mammal. The method comprises administering to the mammal a non-subgroup C adenoviral vector comprising an adenoviral fiber protein having an amino acid sequence comprising about 80% or more identity to an amino acid sequence encoding a subgroup C adenoviral fiber protein. The adenoviral vector further comprises a nucleic acid sequence encoding an antigen which is expressed in the mammal to induce an immune response. The invention further comprises a method of producing an adenoviral vector, and a composition comprising a serotype 41 or a serotype 35 adenoviral vector and a carrier. The invention also provides an adenoviral vector comprising a nucleic acid sequence encoding an adenoviral pIX protein operably linked to a heterologous expression control sequence, as well as a method of enhancing the stability and/or packaging capacity of an adenoviral vector.
摘要翻译： 本发明提供在哺乳动物中诱导免疫应答的方法。 该方法包括向哺乳动物施用非亚组C腺病毒载体，其包含具有与编码亚组C腺病毒纤维蛋白的氨基酸序列具有约80％或更高同一性的氨基酸序列的腺病毒纤维蛋白。 腺病毒载体还包含编码在哺乳动物中表达以诱导免疫应答的抗原的核酸序列。 本发明还包括产生腺病毒载体的方法和包含血清型41或血清型35腺病毒载体和载体的组合物。 本发明还提供了一种腺病毒载体，其包含编码与异源表达控制序列可操作地连接的腺病毒pIX蛋白的核酸序列，以及增强腺病毒载体的稳定性和/或包装能力的方法。
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