公开(公告)号：US20050155608A1

公开(公告)日：2005-07-21

申请号：US10843990

申请日：2004-05-12

申请人： Dusan Pavcnik ,  John Kaufman ,  Clay Fette

发明人： Dusan Pavcnik ,  John Kaufman ,  Clay Fette

IPC分类号： A61B17/00 ,  A61B17/12 ,  A61F2/06 ,  A61F6/22 ,  A61F6/24 ,  A61M29/00 ,  A61F6/06

CPC分类号： A61B17/0057 ,  A61B17/00234 ,  A61B17/12022 ,  A61B17/12109 ,  A61B17/12113 ,  A61B17/12118 ,  A61B17/1219 ,  A61B2017/00004 ,  A61B2017/00637 ,  A61B2017/00641 ,  A61B2017/00654 ,  A61B2017/00898 ,  A61F2/07 ,  A61F2/89 ,  A61F6/225 ,  A61F6/24 ,  A61F2002/061 ,  A61F2002/065 ,  A61F2002/077 ,  A61F2230/005

摘要： An absorbable and expandable closure member used to occlude or exclude a body lumen or cavity, such as a blood vessel, fallopian tube, duct, aneurysmal sac, etc., comprising a closure member comprising one of more sheets of a biomaterial that are rolled, stacked, or folded to form a multilayer construct of a generally cylindrical configuration for deployment through a delivery system, either as a singularly or part of a multiplicity of closure members. The biomaterial is derived from a source material, such as small intestinal submucosa or another remodelable material (e.g., an extracellular matrix) having properties for stimulating ingrowth of adjacent tissue into the biomaterial deployed within the bodily lumen. The closure member is deployed to the bodily lumen from a delivery sheath, cartridge, and/or over a inner guiding member, such as a wire guide or catheter.

摘要翻译： 一种可吸收和可膨胀的封闭构件，其用于闭塞或排除体腔或腔体，例如血管，输卵管，导管，动脉瘤囊等，其包括封闭构件，该闭合构件包括多个生物材料片材中的一个， 堆叠或折叠以形成大致圆柱形构造的多层构造，用于通过输送系统进行部署，作为单个或多个闭合构件的一部分。 生物材料衍生自源材料，例如小肠粘膜下层或具有用于刺激相邻组织的向内生长进入体内部署的生物材料的特性的另一种可重塑材料（例如细胞外基质）。 封闭构件从输送护套，药筒和/或内部引导构件（例如电线引导件或导管）部署到身体管腔。

公开(公告)号：US20070166345A1

公开(公告)日：2007-07-19

申请号：US11442687

申请日：2006-05-26

申请人： Dusan Pavcnik ,  John Kaufman ,  Thomas Osborne ,  Brian Bates ,  Umesh Patel ,  Clay Fette ,  Likang Chin ,  Chad McAlexander ,  Bhavin Shah

发明人： Dusan Pavcnik ,  John Kaufman ,  Thomas Osborne ,  Brian Bates ,  Umesh Patel ,  Clay Fette ,  Likang Chin ,  Chad McAlexander ,  Bhavin Shah

IPC分类号： A61F2/00

CPC分类号： A61B17/12109 ,  A61B17/00008 ,  A61B17/12022 ,  A61B17/12181 ,  A61B17/32053 ,  A61B2017/12054 ,  A61L2430/36

摘要： Described are devices, methods and systems useful for achieving occlusion of vascular vessels. Percutaneous procedures are used to occlude and obliterate the greater saphenous vein, for example in the treatment of varicose vein condition caused by venous reflux. Certain embodiments encompass the deployment of one or more vascular occlusion devices via a through-and-through percutaneous procedure that leaves the vascular occlusion device or devices in a through-and-through condition.

摘要翻译： 描述了用于实现血管血管阻塞的装置，方法和系统。 经皮手术用于闭塞和闭塞较大的隐静脉，例如用于治疗由静脉回流引起的静脉曲张病变。 某些实施方案包括经由通过和经过经皮程序的一个或多个血管闭塞装置的部署，其使得血管闭塞装置或穿通状态离开。

公开(公告)号：US08317823B2

公开(公告)日：2012-11-27

申请号：US12109574

申请日：2008-04-25

申请人： Dusan Pavcnik ,  John Kaufman ,  Clay D. Fette

发明人： Dusan Pavcnik ,  John Kaufman ,  Clay D. Fette

IPC分类号： A61B17/08

CPC分类号： A61B17/0057 ,  A61B17/00234 ,  A61B17/12022 ,  A61B17/12109 ,  A61B17/12113 ,  A61B17/12118 ,  A61B17/1219 ,  A61B2017/00004 ,  A61B2017/00637 ,  A61B2017/00641 ,  A61B2017/00654 ,  A61B2017/00898 ,  A61F2/07 ,  A61F2/89 ,  A61F6/225 ,  A61F6/24 ,  A61F2002/061 ,  A61F2002/065 ,  A61F2002/077 ,  A61F2230/005

摘要： An absorbable and expandable closure member used to occlude or exclude a body lumen or cavity, such as a blood vessel, fallopian tube, duct, aneurysmal sac, etc., comprising a closure member comprising one of more sheets of a biomaterial that are rolled, stacked, or folded to form a multilayer construct of a generally cylindrical configuration for deployment through a delivery system, either as a singularly or part of a multiplicity of closure members. The biomaterial is derived from a source material, such as small intestinal submucosa or another remodelable material (e.g., an extracellular matrix) having properties for stimulating ingrowth of adjacent tissue into the biomaterial deployed within the bodily lumen. The closure member is deployed to the bodily lumen from a delivery sheath, cartridge, and/or over a inner guiding member, such as a wire guide or catheter.

摘要翻译： 一种可吸收和可膨胀的封闭构件，其用于闭塞或排除体腔或腔体，例如血管，输卵管，导管，动脉瘤囊等，其包括封闭构件，该闭合构件包括多个生物材料片材中的一个， 堆叠或折叠以形成大致圆柱形构造的多层构造，用于通过输送系统进行部署，作为单个或多个闭合构件的一部分。 生物材料衍生自源材料，例如小肠粘膜下层或具有用于刺激相邻组织的向内生长进入体内部署的生物材料的特性的另一种可重塑材料（例如细胞外基质）。 封闭构件从输送护套，药筒和/或内部引导构件（例如电线引导件或导管）部署到身体管腔。

公开(公告)号：US09861517B2

公开(公告)日：2018-01-09

申请号：US10206480

申请日：2002-07-26

申请人： Dusan Pavcnik ,  Martina Bastin Pavcnik ,  John Kaufman ,  Joseph F. Obermiller ,  Rodney W. Bosley, Jr.

发明人： Dusan Pavcnik ,  Martina Bastin Pavcnik ,  John Kaufman ,  Joseph F. Obermiller ,  Rodney W. Bosley, Jr.

IPC分类号： A61F6/20 ,  A61F6/24 ,  A61B17/00 ,  A61B17/12

CPC分类号： A61F6/24 ,  A61B17/0057 ,  A61B17/12022 ,  A61B17/12109 ,  A61B17/12118 ,  A61B17/1219 ,  A61B2017/00637 ,  A61B2017/00641 ,  A61B2017/00654 ,  A61B2017/00672 ,  A61B2017/00898

摘要： An apparatus which includes a closure member and delivery systems for closing vessels in the body of a patient is disclosed. In one embodiment, the closure member is a hemostatic closure member having a cylindrical shape and an expandable volume on contact with fluids. The hemostatic member includes a functional passageway through the length of the member so that it may be mounted over a delivery catheter or wire guide for delivery against a vessel puncture or into another vacuslar environment, such as to fill an aneurysm sac. In another embodiment the closure member is a fallopian tube closure member which is deployed into the fallopian tube over a guide wire to prevent conception. The fallopian tube member includes a loop-shaped frame having barbs, a first layer of material, a binding wire, a second layer of material, and an expandable volume on contact with fluids.

公开(公告)号：US20140148839A1

公开(公告)日：2014-05-29

申请号：US13686569

申请日：2012-11-27

申请人： Dusan Pavcnik ,  John Kaufman ,  Clay D. Fette

发明人： Dusan Pavcnik ,  John Kaufman ,  Clay D. Fette

IPC分类号： A61B17/12

CPC分类号： A61B17/12131 ,  A61B17/00234 ,  A61B17/0057 ,  A61B17/12022 ,  A61B17/12109 ,  A61B17/12113 ,  A61B17/12118 ,  A61B17/1219 ,  A61B2017/00004 ,  A61B2017/00637 ,  A61B2017/00641 ,  A61B2017/00654 ,  A61B2017/00898 ,  A61F2/07 ,  A61F2/89 ,  A61F6/225 ,  A61F6/24 ,  A61F2002/061 ,  A61F2002/065 ,  A61F2002/077 ,  A61F2230/005

摘要： An absorbable and expandable closure member used to occlude or exclude a body lumen or cavity, such as a blood vessel, fallopian tube, duct, aneurysmal sac, etc., comprising a closure member comprising one of more sheets of a biomaterial that are rolled, stacked, or folded to form a multilayer construct of a generally cylindrical configuration for deployment through a delivery system, either as a singularly or part of a multiplicity of closure members. The biomaterial is derived from a source material, such as small intestinal submucosa or another remodelable material (e.g., an extracellular matrix) having properties for stimulating ingrowth of adjacent tissue into the biomaterial deployed within the bodily lumen. The closure member is deployed to the bodily lumen from a delivery sheath, cartridge, and/or over a inner guiding member, such as a wire guide or catheter.

摘要翻译： 一种可吸收和可膨胀的封闭构件，其用于闭塞或排除体腔或腔体，例如血管，输卵管，导管，动脉瘤囊等，其包括封闭构件，该闭合构件包括多个生物材料片材中的一个， 堆叠或折叠以形成大致圆柱形构造的多层构造，用于通过输送系统进行部署，作为单个或多个闭合构件的一部分。 生物材料衍生自源材料，例如小肠粘膜下层或具有用于刺激相邻组织的向内生长进入体内部署的生物材料的特性的另一种可重塑材料（例如细胞外基质）。 封闭构件从输送护套，药筒和/或内部引导构件（例如电线引导件或导管）部署到身体管腔。

公开(公告)号：US08465516B2

公开(公告)日：2013-06-18

申请号：US10843990

申请日：2004-05-12

申请人： Dusan Pavcnik ,  John Kaufman ,  Clay D. Fette

发明人： Dusan Pavcnik ,  John Kaufman ,  Clay D. Fette

IPC分类号： A61B17/08

CPC分类号： A61B17/0057 ,  A61B17/00234 ,  A61B17/12022 ,  A61B17/12109 ,  A61B17/12113 ,  A61B17/12118 ,  A61B17/1219 ,  A61B2017/00004 ,  A61B2017/00637 ,  A61B2017/00641 ,  A61B2017/00654 ,  A61B2017/00898 ,  A61F2/07 ,  A61F2/89 ,  A61F6/225 ,  A61F6/24 ,  A61F2002/061 ,  A61F2002/065 ,  A61F2002/077 ,  A61F2230/005

摘要： An absorbable and expandable closure member used to occlude or exclude a body lumen or cavity, such as a blood vessel, fallopian tube, duct, aneurysmal sac, etc., comprising a closure member comprising one of more sheets of a biomaterial that are rolled, stacked, or folded to form a multilayer construct of a generally cylindrical configuration for deployment through a delivery system, either as a singularly or part of a multiplicity of closure members. The biomaterial is derived from a source material, such as small intestinal submucosa or another remodelable material (e.g., an extracellular matrix) having properties for stimulating ingrowth of adjacent tissue into the biomaterial deployed within the bodily lumen. The closure member is deployed to the bodily lumen from a delivery sheath, cartridge, and/or over a inner guiding member, such as a wire guide or catheter.

摘要翻译： 一种可吸收和可膨胀的封闭构件，其用于闭塞或排除体腔或腔体，例如血管，输卵管，导管，动脉瘤囊等，其包括封闭构件，该闭合构件包括多个生物材料片材中的一个， 堆叠或折叠以形成大致圆柱形构造的多层构造，用于通过输送系统进行部署，作为单个或多个闭合构件的一部分。 生物材料衍生自源材料，例如小肠粘膜下层或具有用于刺激相邻组织的向内生长进入体内部署的生物材料的特性的另一种可重塑材料（例如细胞外基质）。 封闭构件从输送护套，药筒和/或内部引导构件（例如电线引导件或导管）部署到身体管腔。

公开(公告)号：US20080215087A1

公开(公告)日：2008-09-04

申请号：US12109574

申请日：2008-04-25

申请人： Dusan Pavcnik ,  John Kaufman ,  Clay D. Fette

发明人： Dusan Pavcnik ,  John Kaufman ,  Clay D. Fette

IPC分类号： A61B17/12 ,  A61F6/20

CPC分类号： A61B17/0057 ,  A61B17/00234 ,  A61B17/12022 ,  A61B17/12109 ,  A61B17/12113 ,  A61B17/12118 ,  A61B17/1219 ,  A61B2017/00004 ,  A61B2017/00637 ,  A61B2017/00641 ,  A61B2017/00654 ,  A61B2017/00898 ,  A61F2/07 ,  A61F2/89 ,  A61F6/225 ,  A61F6/24 ,  A61F2002/061 ,  A61F2002/065 ,  A61F2002/077 ,  A61F2230/005

摘要： An absorbable and expandable closure member used to occlude or exclude a body lumen or cavity, such as a blood vessel, fallopian tube, duct, aneurysmal sac, etc., comprising a closure member comprising one of more sheets of a biomaterial that are rolled, stacked, or folded to form a multilayer construct of a generally cylindrical configuration for deployment through a delivery system, either as a singularly or part of a multiplicity of closure members. The biomaterial is derived from a source material, such as small intestinal submucosa or another remodelable material (e.g., an extracellular matrix) having properties for stimulating ingrowth of adjacent tissue into the biomaterial deployed within the bodily lumen. The closure member is deployed to the bodily lumen from a delivery sheath, cartridge, and/or over a inner guiding member, such as a wire guide or catheter.

摘要翻译： 一种可吸收和可膨胀的封闭构件，其用于闭塞或排除体腔或腔体，例如血管，输卵管，导管，动脉瘤囊等，其包括封闭构件，该闭合构件包括多个生物材料片材中的一个， 堆叠或折叠以形成大致圆柱形构造的多层构造，用于通过输送系统进行部署，作为单个或多个闭合构件的一部分。 生物材料衍生自源材料，例如小肠粘膜下层或具有用于刺激相邻组织的向内生长进入体内部署的生物材料的特性的另一种可重塑材料（例如细胞外基质）。 封闭构件从输送护套，药筒和/或内部引导构件（例如电线引导件或导管）部署到身体管腔。

公开(公告)号：US09414843B2

公开(公告)日：2016-08-16

申请号：US11442687

申请日：2006-05-26

申请人： Dusan Pavcnik ,  John A. Kaufman ,  Thomas Osborne ,  Brian Bates ,  Umesh Patel ,  Likang Chin ,  Chad S. McAlexander ,  Bhavin Shah

发明人： Dusan Pavcnik ,  John A. Kaufman ,  Thomas Osborne ,  Brian Bates ,  Umesh Patel ,  Clay D. Fette ,  Likang Chin ,  Chad S. McAlexander ,  Bhavin Shah

IPC分类号： A61M29/00 ,  A61B17/12 ,  A61B17/00 ,  A61B17/3205

CPC分类号： A61B17/12109 ,  A61B17/00008 ,  A61B17/12022 ,  A61B17/12181 ,  A61B17/32053 ,  A61B2017/12054 ,  A61L2430/36

摘要： Described are devices, methods and systems useful for achieving occlusion of vascular vessels. Percutaneous procedures are used to occlude and obliterate the greater saphenous vein, for example in the treatment of varicose vein condition caused by venous reflux. Certain embodiments encompass the deployment of one or more vascular occlusion devices via a through-and-through percutaneous procedure that leaves the vascular occlusion device or devices in a through-and-through condition.

摘要翻译： 描述了用于实现血管血管阻塞的装置，方法和系统。 经皮手术用于闭塞和闭塞较大的隐静脉，例如用于治疗由静脉回流引起的静脉曲张病变。 某些实施方案包括经由通过和经过经皮程序的一个或多个血管闭塞装置的部署，其使得血管闭塞装置或穿通状态离开。

公开(公告)号：US08444687B2

公开(公告)日：2013-05-21

申请号：US12393819

申请日：2009-02-26

申请人： Dusan Pavcnik ,  Frederick S. Keller ,  Josef Rosch ,  Thomas A. Osborne ,  Brian L. Bates ,  Christopher G. Dixon ,  Andrew K. Hoffa ,  Raymond B. Leonard, II ,  Joseph F. Obermiller ,  John A. DeFord ,  Joseph W. Roberts

发明人： Dusan Pavcnik ,  Frederick S. Keller ,  Josef Rosch ,  Thomas A. Osborne ,  Brian L. Bates ,  Christopher G. Dixon ,  Andrew K. Hoffa ,  Raymond B. Leonard, II ,  Joseph F. Obermiller ,  John A. DeFord ,  Joseph W. Roberts

IPC分类号： A61F2/06 ,  A61F2/24

CPC分类号： A61F2/01 ,  A61F2/2418 ,  A61F2/2475 ,  A61F2002/018 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0075 ,  A61F2230/0008 ,  A61F2230/001 ,  A61F2230/0023 ,  A61F2230/0026 ,  A61F2230/0054 ,  A61F2230/0058 ,  A61F2230/0095 ,  Y10S623/901

摘要： A multiple-sided medical device comprises a frame comprising wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration which a generally serpentine shape. The device is pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs for anchoring purposes. A full or partial covering of fabric or other flexible material such as DACRON, PTFE, or a collagen-based material such as small intestinal submucosa (SIS), may be sutured or attached to the frame using heat or pressure welding crimping, adhesive, or other techniques to form an occlusion device, a stent graft, or an implantable, intraluminal valve such as for correcting incompetent veins in the lower legs and feet.

公开(公告)号：US08444666B2

公开(公告)日：2013-05-21

申请号：US10662216

申请日：2003-09-12

申请人： Dusan Pavcnik ,  Brian C. Case ,  John A. Kaufman ,  Michael L. Garrison ,  Jacob A. Flagle

发明人： Dusan Pavcnik ,  Brian C. Case ,  John A. Kaufman ,  Michael L. Garrison ,  Jacob A. Flagle

IPC分类号： A61B17/00 ,  A61F2/06 ,  A61F2/82

CPC分类号： A61F2/01 ,  A61F2002/016 ,  A61F2230/005 ,  A61F2230/0067

摘要： A filter may have an apical hub and a plurality of divergent legs. A first attachment member may be separate from, but attached to the second end of at least one of the plurality of divergent legs. A second attachment member may be separate from, but attached to a stent. The first and second attachment members may be separate from, but attachable to one another to releasably attach the filter to the stent. One of the first attachment member and the second attachment member may include an attachment wire that is positioned in a lumen of a tubular member or one of the first attachment member and the second attachment member may comprise a cannula. In some implementations, an upward motion applied to the retrieval connection member may disengage at least one attachment wire of the first attachment member from the second attachment member.

摘要翻译： 过滤器可以具有顶端毂和多个发散腿。 第一附接构件可以与多个发散腿中的至少一个分开，但是附接到多个发散腿中的至少一个的第二端。 第二附接构件可以与支架分离但附接到支架。 第一和第二附接构件可以彼此分离，但可彼此附接以将过滤器可释放地附接到支架。 第一附接构件和第二附接构件中的一个可以包括定位在管状构件的内腔中的附接线，或者第一附接构件和第二附接构件中的一个可以包括套管。 在一些实施方式中，施加到取回连接构件的向上运动可以使第一附接构件的至少一个附接线与第二附接构件脱离接触。