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公开(公告)号:US10059709B2
公开(公告)日:2018-08-28
申请号:US15119800
申请日:2015-03-25
发明人: Noelle Gauvry , Chouaib Tahtaoui , Pascal Furet , Pierre Ducray
IPC分类号: C07D471/14 , C07D239/46 , C07D471/04 , A61K31/44 , C07D473/34 , C07D487/04 , C07D495/04 , C07D239/42 , C07D239/48
CPC分类号: C07D471/14 , C07D239/42 , C07D239/46 , C07D239/48 , C07D471/04 , C07D473/34 , C07D487/04 , C07D495/04
摘要: The invention relates to a compound of formula (I) wherein the variables have the meaning as indicated in the claims; in free form and in salt form; and optionally the enantiomers and geometrical isomers thereof. The compounds of formula (I) are useful as therapeutic agent for organ transplants, lupus, multiple sclerosis, rheumatoid arthritis, psoriasis, Type I diabetes and complications from diabetes, cancer, asthma, atopic dermatitis, autoimmune thyroid disorders, ulcerative colitis, inflammatory bowel diseases, Crohn's disease, Alzheimer's disease, leukemia, osteoarthritis, control of pruritus, chronic respiratory disease or keratoconjunctivitis in mammals.
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公开(公告)号:US10047040B2
公开(公告)日:2018-08-14
申请号:US15502512
申请日:2015-08-27
发明人: Noelle Gauvry , Chouaib Tahtaoui
IPC分类号: C07C311/08 , C07F7/08 , C07F5/02 , C07D295/155 , C07D333/24 , C07D231/12 , C07D213/61 , C07D231/56 , C07D213/56 , C07D239/30 , C07D239/26 , C07D277/30 , C07D213/84 , C07D333/28 , C07C311/21 , C07C311/14 , C07D309/06 , C07D249/08 , C07D277/64 , C07D277/60 , C07D277/56 , C07D285/135 , C07D333/78 , C07D277/46 , C07D277/54 , C07D263/50 , C07D275/03 , C07D317/66 , C07D209/08 , C07D215/06 , C07D487/04 , C07D237/26
CPC分类号: C07C311/08 , C07C235/56 , C07C307/10 , C07C311/09 , C07C311/10 , C07C311/14 , C07C311/21 , C07C311/29 , C07C2601/02 , C07C2601/14 , C07C2602/08 , C07C2602/40 , C07C2602/42 , C07D209/08 , C07D213/26 , C07D213/56 , C07D213/61 , C07D213/64 , C07D213/65 , C07D213/84 , C07D215/06 , C07D231/12 , C07D231/20 , C07D231/56 , C07D237/26 , C07D239/26 , C07D239/30 , C07D239/34 , C07D249/08 , C07D249/12 , C07D263/50 , C07D275/03 , C07D277/30 , C07D277/46 , C07D277/54 , C07D277/56 , C07D277/60 , C07D277/62 , C07D277/64 , C07D279/12 , C07D285/135 , C07D295/155 , C07D295/185 , C07D295/26 , C07D309/06 , C07D317/66 , C07D333/24 , C07D333/28 , C07D333/78 , C07D487/04 , C07F5/025 , C07F7/081 , C07F7/0812
摘要: The present invention relates to a new compound of formula (I) wherein the variables have the meaning as indicated in the claims; or an enantiomer or salt thereof. The compounds of formula (I) are useful in the control of parasites, in particular endoparasites, in and on vertebrates.
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公开(公告)号:US10464889B2
公开(公告)日:2019-11-05
申请号:US16037396
申请日:2018-07-17
发明人: Noelle Gauvry , Chouaib Tahtaoui
IPC分类号: C07C311/08 , C07D277/62 , C07D213/61 , C07D213/84 , C07D231/12 , C07D231/20 , C07D231/56 , C07C307/10 , C07D333/24 , C07D333/28 , C07C311/10 , C07C311/14 , C07C311/21 , C07C311/29 , C07D239/26 , C07D239/30 , C07D239/34 , C07D249/12 , C07D277/30 , C07D277/64 , C07D279/12 , C07D295/155 , C07D295/185 , C07D295/26 , C07D213/26 , C07D213/64 , C07D213/65 , C07C311/09 , C07C235/56 , C07F5/02 , C07F7/08 , C07D209/08 , C07D213/56 , C07D215/06 , C07D237/26 , C07D249/08 , C07D263/50 , C07D275/03 , C07D277/46 , C07D277/54 , C07D277/56 , C07D277/60 , C07D285/135 , C07D309/06 , C07D317/66 , C07D333/78 , C07D487/04
摘要: The present invention relates to a new compound of formula (I) wherein the variables have the meaning as indicated in the claims; or an enantiomer or salt thereof. The compounds of formula (I) are useful in the control of parasites, in particular endoparasites, in and on vertebrates.
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公开(公告)号:US10370375B2
公开(公告)日:2019-08-06
申请号:US16055560
申请日:2018-08-06
发明人: Noelle Gauvry , Chouaib Tahtaoui , Pascal Furet , Pierre Ducray
IPC分类号: C07D471/14 , C07D239/46 , C07D471/04 , C07D473/34 , C07D487/04 , C07D495/04 , C07D239/42 , C07D239/48
摘要: The invention relates to a compound of formula (I) wherein the variables have the meaning as indicated in the claims; in free form and in salt form; and optionally the enantiomers and geometrical isomers thereof. The compounds of formula (I) are useful as therapeutic agent for organ transplants, lupus, multiple sclerosis, rheumatoid arthritis, psoriasis. Type I diabetes and complications from diabetes, cancer, asthma, atopic dermatitis, autoimmune thyroid disorders, ulcerative colitis, inflammatory bowel diseases, Crohn's disease, Alzheimer's disease, leukemia, osteoarthritis, control of pruritus, chronic respiratory disease or keratoconjunctivitis in mammals.
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公开(公告)号:US20180346465A1
公开(公告)日:2018-12-06
申请号:US16055560
申请日:2018-08-06
发明人: Noelle Gauvry , Chouaib Tahtaoui , Pascal Furet , Pierre Ducray
IPC分类号: C07D471/14 , C07D239/48 , C07D471/04 , C07D473/34 , C07D487/04 , C07D495/04 , C07D239/42 , C07D239/46
CPC分类号: C07D471/14 , C07D239/42 , C07D239/46 , C07D239/48 , C07D471/04 , C07D473/34 , C07D487/04 , C07D495/04
摘要: The invention relates to a compound of formula (I) wherein the variables have the meaning as indicated in the claims; in free form and in salt form; and optionally the enantiomers and geometrical isomers thereof. The compounds of formula (I) are useful as therapeutic agent for organ transplants, lupus, multiple sclerosis, rheumatoid arthritis, psoriasis. Type I diabetes and complications from diabetes, cancer, asthma, atopic dermatitis, autoimmune thyroid disorders, ulcerative colitis, inflammatory bowel diseases, Crohn's disease, Alzheimer's disease, leukemia, osteoarthritis, control of pruritus, chronic respiratory disease or keratoconjunctivitis in mammals.
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公开(公告)号:US20180319741A1
公开(公告)日:2018-11-08
申请号:US16037396
申请日:2018-07-17
发明人: Noelle Gauvry , Chouaib Tahtaoui
IPC分类号: C07C311/08 , C07F7/08 , C07D237/26 , C07D487/04 , C07D215/06 , C07D209/08 , C07D317/66 , C07D275/03 , C07D263/50 , C07D277/54 , C07D277/46 , C07D333/78 , C07D285/135 , C07D277/56 , C07D277/60 , C07D277/64 , C07D249/08 , C07D309/06 , C07C311/14 , C07C311/21 , C07D333/28 , C07D213/84 , C07D277/30 , C07D239/26 , C07D239/30 , C07D213/56 , C07D231/56 , C07D213/61 , C07D231/12 , C07D333/24 , C07D295/155 , C07F5/02
CPC分类号: C07C311/08 , C07C235/56 , C07C307/10 , C07C311/09 , C07C311/10 , C07C311/14 , C07C311/21 , C07C311/29 , C07C2601/02 , C07C2601/14 , C07C2602/08 , C07C2602/40 , C07C2602/42 , C07D209/08 , C07D213/26 , C07D213/56 , C07D213/61 , C07D213/64 , C07D213/65 , C07D213/84 , C07D215/06 , C07D231/12 , C07D231/20 , C07D231/56 , C07D237/26 , C07D239/26 , C07D239/30 , C07D239/34 , C07D249/08 , C07D249/12 , C07D263/50 , C07D275/03 , C07D277/30 , C07D277/46 , C07D277/54 , C07D277/56 , C07D277/60 , C07D277/62 , C07D277/64 , C07D279/12 , C07D285/135 , C07D295/155 , C07D295/185 , C07D295/26 , C07D309/06 , C07D317/66 , C07D333/24 , C07D333/28 , C07D333/78 , C07D487/04 , C07F5/025 , C07F7/081 , C07F7/0812
摘要: The present invention relates to a new compound of formula (I) wherein the variables have the meaning as indicated in the claims; or an enantiomer or salt thereof. The compounds of formula (I) are useful in the control of parasites, in particular endoparasites, in and on vertebrates.
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