公开(公告)号：US20170165638A1

公开(公告)日：2017-06-15

申请号：US15323471

申请日：2015-08-19

Applicant: EMD Millipore Corporation

Inventor： John Paul Amara ,  John Boyle ,  David Yavorsky ,  Benjamin Cacace

IPC: B01J20/285 ,  B01D15/32 ,  B01D15/38 ,  B01J47/127 ,  B01J20/28 ,  B01J39/19 ,  B01J41/13 ,  B01D15/36 ,  C12N7/00

Abstract: Chromatography media including a high surface area thermoplastic porous nanofiber and an ion-exchange ligand functionality on the surface of the fiber. The porous nanofibers display a convoluted structure that is comprised of discrete bundles of highly entangled nanofibrils that may be fibrillated or ridged. The porous fibers can be prepared through the extraction of a dissolvable mineral or polymeric porogen that is embedded into the fiber during its manufacture in a melt extrusion process.

公开(公告)号：US10449517B2

公开(公告)日：2019-10-22

申请号：US15323471

申请日：2015-08-19

Applicant: EMD Millipore Corporation

Inventor： John Paul Amara ,  John Boyle ,  David Yavorsky ,  Benjamin Cacace

IPC: B01J20/285 ,  B01D15/32 ,  B01J20/26 ,  B01J20/28 ,  B01J20/281 ,  B01J20/32 ,  C07K1/16 ,  B01D15/36 ,  B01D15/38 ,  B01J39/19 ,  B01J47/127 ,  B01J41/13 ,  C12N7/00 ,  B01J39/26 ,  B01J41/20 ,  C07K1/18 ,  C07K1/20 ,  C07K1/22

Abstract: Chromatography media including a high surface area thermoplastic porous nanofiber and an ion-exchange ligand functionality on the surface of the fiber. The porous nanofibers display a convoluted structure that is comprised of discrete bundles of highly entangled nanofibrils that may be fibrillated or ridged. The porous fibers can be prepared through the extraction of a dissolvable mineral or polymeric porogen that is embedded into the fiber during its manufacture in a melt extrusion process.