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公开(公告)号：US20230023196A1
公开(公告)日：2023-01-26
申请号：US17871579
申请日：2022-07-22
申请人： ENTEGRIS, INC.
发明人： Nicholas Coscia
摘要： A bag holder for supporting a bioprocess bag during freezing includes a cover, a bottom, a frame, and at least one bag support. The cover, the bottom, and the frame form an enclosed space. The at least one bag support is disposed in the space. The cover and the bottom are made of metal. The frame has a first side, a second side, a front end, and a back end. Each of the cover and the bottom has a first bendable tab and a second bendable tab configured to bend over the front end from a longitudinal direction to a thickness direction, and a first arm and a second arm extending in the thickness direction and then in the longitudinal direction. Each of the first side and the second side includes at least one recessed portion extending in the longitudinal direction.
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公开(公告)号：US12116169B2
公开(公告)日：2024-10-15
申请号：US18100493
申请日：2023-01-23
申请人： ENTEGRIS, INC.
发明人： Nicholas Coscia
CPC分类号： B65D25/48 , B65D47/061 , B65D47/248 , B67C3/04 , B65D47/32
摘要： An aseptic closure assembly for a fluid container that includes a cap connectable to an opening of the fluid container and a fluid dispenser connectable to an outer surface of the housing of the cap. The fluid dispenser includes a main body and fluid lines provided within the main body, a shell housing provided around the main body, and an insert connectable to a second end of the main body. The main body includes apertures nearer the second end that are connected to the fluid lines and configured to be in fluid communication with the fluid container when the fluid dispenser is connected to the cap. The fluid dispenser is configured such that a downward directed force towards the fluid container fits the insert into the support of the cavity and disconnects the insert from the main body of the fluid dispenser to seal the fluid container.
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公开(公告)号：US20230064103A1
公开(公告)日：2023-03-02
申请号：US17894905
申请日：2022-08-24
申请人： ENTEGRIS, INC.
发明人： Nicholas Coscia
摘要： A transfer container for a fluid includes a tube, the tube including a conical portion at one end, the tube defining an interior space and one or more fluid passages configured to allow flow of fluid into or out of the interior space of the tube. The transfer container also includes a connector configured to seal the end of the conical portion when the connector is joined only to the conical portion and a pressure control mechanism configured to increase or decrease a pressure in the interior space of the tube. The transfer container can be used in a method including connecting fluid lines to the fluid passages, adding a fluid including cryoprotectant and cells, centrifuging the transfer container, and then connecting the transfer container to a second fluid transfer container containing another fluid. This allows the sterile transfer of fluids and separation of cells from cryoprotectant.
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公开(公告)号：US20240174411A1
公开(公告)日：2024-05-30
申请号：US18515101
申请日：2023-11-20
申请人： ENTEGRIS, INC.
CPC分类号： B65D47/10 , B65B51/10 , B65D2517/5024
摘要： A fitment for a bag includes an integrally formed spike port, the spike port including an aperture, a puncture barrier film and an internal gasket. The fitment can be a fluoropolymer. The puncture barrier can be a fluoropolymer film. The internal gasket is positioned within the aperture and provides an additional puncture barrier to the spike port. The fitment can be incorporated into a bag by joining two sheets such as fluoropolymer sheets to one another and to the fitment around a perimeter of the sheets. The bag can be used in processes including exposure to or holding at cryogenic temperatures.
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公开(公告)号：US20240116686A1
公开(公告)日：2024-04-11
申请号：US18378110
申请日：2023-10-09
申请人： ENTEGRIS, INC.
IPC分类号： B65D55/10 , B65D43/02 , B65D81/133
CPC分类号： B65D55/10 , B65D43/0233 , B65D81/133 , B65D2543/00277 , B65D2581/055
摘要： A storage container that includes a housing having a bottom surface, two side walls, a front wall, and a back wall that form an interior space in the housing. The storage container also includes a lid configured to enclose the interior space. The two side walls of the housing include a rim portion and the lid includes a rail portion configured to provide a non-destructive and deformable locking and unlocking engagement with the rim portion. The back wall of the housing includes a first segment and a second segment, the second segment being separated a distance longitudinally from the first segment and connected to the first segment by a secondary bottom surface such that the second section of the interior space has a greater volume than the first section of the interior space.
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公开(公告)号：US20220298462A1
公开(公告)日：2022-09-22
申请号：US17698104
申请日：2022-03-18
申请人： ENTEGRIS, INC.
发明人： Nicholas Coscia
摘要： Bag holders for plate freezing of bags containing fluids such as reactor bags, in particular bags containing biological or chemical reagents can include genderless bag trays. Each bag tray can include a basin defined in part by a first side wall and a second side wall. The basin can be configured to hold the bag. The first side wall can include a first retaining feature and the second side wall can include a second retaining feature having a shape complementary to the first retaining feature. The complementary nature of first and second retaining features allows identical bag trays to be joined by each of their respective first and second retaining features to one another. Methods include forming first and second bag trays, placing a bag within the first bag tray, joining the second bag tray to the first bag tray, and freezing the bag by a plate freezing process.
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公开(公告)号：USD1015569S1
公开(公告)日：2024-02-20
申请号：US29774971
申请日：2021-03-19
申请人： ENTEGRIS, INC.
设计人： Nicholas Coscia
摘要： FIG. 1 is a top-front-left perspective view of a bag holding tray showing my new design;
FIG. 2 is an enlarged view of area 2 encircled in FIG. 1;
FIG. 3 is an enlarged view of area 3 encircled in FIG. 1;
FIG. 4 is a top-rear-right perspective view of the bag holding tray;
FIG. 5 is an enlarged view of area 5 encircled in FIG. 4;
FIG. 6 is an enlarged view of area 6 encircled in FIG. 4;
FIG. 7 is a bottom-front-left perspective view of the bag holding tray;
FIG. 8 is an enlarged view of area 8 encircled in FIG. 7;
FIG. 9 is a bottom-rear-right perspective view of the bag holding tray;
FIG. 10 is an enlarged view of area 10 encircled in FIG. 9;
FIG. 11 is an enlarged view of area 11 encircled in FIG. 9;
FIG. 12 is a top view of the bag holding tray;
FIG. 13 is an enlarged view of area 13 encircled in FIG. 12;
FIG. 14 is a bottom view of the bag holding tray;
FIG. 15 is an enlarged view of area 15 encircled in FIG. 6A;
FIG. 16 is an enlarged view of area 16 encircled in FIG. 14;
FIG. 17 is a front view of the bag holding tray;
FIG. 18 is an enlarged view of area 18 encircled in FIG. 17;
FIG. 19 is a rear view of the bag holding tray;
FIG. 20 is an enlarged view of area 20 encircled in FIG. 19;
FIG. 21 is a left side view of the bag holding tray; and,
FIG. 22 is an enlarged view of area 22 encircled in FIG. 21.
The broken lines in the drawings depict portions of the bag holding tray that form no part of the claimed design.-
公开(公告)号：USD1011551S1
公开(公告)日：2024-01-16
申请号：US29774988
申请日：2021-03-19
申请人： ENTEGRIS, INC.
设计人： Nicholas Coscia
摘要： FIG. 1 is a top-front-left perspective view of a bag holding tray showing my new design;
FIG. 2 is an enlarged view of area 2 encircled in FIG. 1;
FIG. 3 is an enlarged view of area 3 encircled in FIG. 1;
FIG. 4 is a top-front-right perspective view of the bag holding tray;
FIG. 5 is an enlarged view of area 5 encircled in FIG. 4;
FIG. 6 is an enlarged view of area 6 encircled in FIG. 4;
FIG. 7 is a bottom-rear-left perspective view of the bag holding tray;
FIG. 8 is an enlarged view of area 8 encircled in FIG. 7;
FIG. 9 is a bottom-rear-right perspective view of the bag holding tray;
FIG. 10 is an enlarged view of area 10 encircled in FIG. 9;
FIG. 11 is an enlarged view of area 11 encircled in FIG. 9;
FIG. 12 is a top view of the bag holding tray;
FIG. 13 is an enlarged view of area 13 encircled in FIG. 12;
FIG. 14 is an enlarged view of area 14 encircled in FIG. 12;
FIG. 15 is a bottom view of the bag holding tray;
FIG. 16 is an enlarged view of area 16 encircled in FIG. 15;
FIG. 17 is an enlarged view of area 17 encircled in FIG. 15;
FIG. 18 is a front view of the bag holding tray;
FIG. 19 is an enlarged view of area 19 encircled in FIG. 18;
FIG. 20 is a rear view of the bag holding tray;
FIG. 21 is an enlarged view of area 21 encircled in FIG. 20;
FIG. 22 is a left side view of the bag holding tray; and,
FIG. 23 is an enlarged view of area 23 encircled in FIG. 22.
The broken lines in the drawings depict portions of the bag holding tray that form no part of the claimed design.
The dot-dot-dash broken lines depict the boundaries of the claim and form no part thereof.-
公开(公告)号：US20230122990A1
公开(公告)日：2023-04-20
申请号：US17827470
申请日：2022-05-27
申请人： ENTEGRIS, INC.
摘要： A bag assembly that includes a bag portion having first and second walls defining an interior and an opening. The interior is formed by the first and second walls of the bag portion being attached to each other along at least a portion of a perimeter of the bag assembly up to one end of the bag portion. Portions of the first and second walls of the bag portion that are not attached to each other form the opening. The bag assembly also includes an aseptic system for sterile connection and disconnection of the bag assembly from a sterile process, the aseptic system being continuously formed at an interface between the aseptic system and the one end of the bag portion. The aseptic system includes an internal passage to allow fluid communication with the interior of the bag portion and the sterile process.
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公开(公告)号：US20220295784A1
公开(公告)日：2022-09-22
申请号：US17698207
申请日：2022-03-18
申请人： ENTEGRIS, INC.
发明人： Nicholas Coscia
摘要： A bag holder for a blast freezing process includes a bag tray. The bag tray is genderless and can be combined with an identical bag tray to form the bag holder. The bag holder includes a basin, side walls, and an end wall. The first and second side walls each include a set of alternating extended and recessed sections and a channel extending through at least a portion of the set of alternating extended and recessed sections. The alternating extended and recessed sections are offset from one another such that where a set on one side wall has an extended section, the set on the other side wall has a recessed section and vice versa. Methods include forming these bag trays, and placing a bag in one bag tray, then joining another bag tray to form the holder around the bag.
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