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公开(公告)号：US11324235B2
公开(公告)日：2022-05-10
申请号：US16934179
申请日：2020-07-21
Applicant: Erber Aktiengesellschaft
Inventor： Sebastian Fruhauf , Michaela Thamhesl , Martin Pfeffer , Dieter Moll , Gerd Schatzmayr , Eva Maria Binder
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
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公开(公告)号：US20200375218A1
公开(公告)日：2020-12-03
申请号：US16934179
申请日：2020-07-21
Applicant: Erber Aktiengesellschaft
Inventor： Sebastian Fruhauf , Michaela Thamhesl , Martin Pfeffer , Dieter Moll , Gerd Schatzmayr , Eva Maria Binder
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
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公开(公告)号：US11998027B2
公开(公告)日：2024-06-04
申请号：US17829416
申请日：2022-06-01
Applicant: Erber Aktiengesellschaft
Inventor： Sebastian Fruhauf , Michaela Thamhesl , Martin Pfeffer , Dieter Moll , Gerd Schatzmayr , Eva Maria Binder
CPC classification number: A23K10/14 , A23K50/30 , A23K50/75 , A23K50/80 , A23L3/3571 , C12N9/14 , C12N9/18 , C12Y301/01 , A23V2002/00 , Y02A40/818
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
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公开(公告)号：US11910807B2
公开(公告)日：2024-02-27
申请号：US17555731
申请日：2021-12-20
Applicant: Erber Aktiengesellschaft
Inventor： Sebastian Fruhauf , Michaela Thamhesl , Martin Pfeffer , Dieter Moll , Gerd Schatzmayr , Eva Maria Binder
CPC classification number: A23K10/14 , A23K50/30 , A23K50/75 , A23K50/80 , A23L3/3571 , C12N9/14 , C12N9/18 , C12Y301/01 , A23V2002/00 , Y02A40/818
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
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公开(公告)号：US11998028B2
公开(公告)日：2024-06-04
申请号：US17829431
申请日：2022-06-01
Applicant: Erber Aktiengesellschaft
Inventor： Sebastian Fruhauf , Michaela Thamhesl , Martin Pfeffer , Dieter Moll , Gerd Schatzmayr , Eva Maria Binder
CPC classification number: A23K10/14 , A23K50/30 , A23K50/75 , A23K50/80 , A23L3/3571 , C12N9/14 , C12N9/18 , C12Y301/01 , A23V2002/00 , Y02A40/818
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
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Patent Agency Ranking
公开(公告)号：US20220287328A1
公开(公告)日：2022-09-15
申请号：US17829431
申请日：2022-06-01
Applicant: Erber Aktiengesellschaft
Inventor： Sebastian FRUHAUF , Michaela Thamhesl , Martin Pfeffer , Dleter Moll , Gerd Schatzmayr , Eva Maria Binder
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
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公开(公告)号：US10149489B2
公开(公告)日：2018-12-11
申请号：US14914671
申请日：2014-08-27
Applicant: Erber Aktiengesellschaft
Inventor： Sebastian Fruhauf , Michaela Thamhesl , Martin Pfeffer , Dieter Moll , Gerd Schatzmayr , Eva Maria Binder
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
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公开(公告)号：US11751985B2
公开(公告)日：2023-09-12
申请号：US16631485
申请日：2018-07-17
Applicant: Erber Aktiengesellschaft
Inventor： Daniel Petri , Luca Stefano Vandi , Eva Maria Binder , Martin Pfeffer , Stephen Charles John Cole , Dante Lorini
CPC classification number: A61D7/00 , A61D1/025 , B05C11/1044 , B05D1/02
Abstract: A dispensing apparatus (1) for delivering droplets of fluids such as liquids having a low viscosity or being soft gels onto poultry hatchlings that are present in movably mounted hatchling trays (19) comprising at least one reservoir (18), at least one pumping unit (9), connected to at least one reservoir (18), with at least one manifold (8) connected to at least one pumping unit (9), as well as a control unit. The apparatus comprises a plurality of optionally adjustable fluid atomizers (6) being connected by flexible connecting means (7) to at least one manifold (8), whereby the fluid atomizers (6) are detachably and/or slidably connected on at least one mounting rail (5), and that optionally different types of fluid atomizers (6) are distributed onto the mounting rail (5). Additionally, a method for delivering fluid droplets onto poultry hatchlings present in moving hatchling trays (19) is described.
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公开(公告)号：US20210371835A1
公开(公告)日：2021-12-02
申请号：US17264096
申请日：2019-07-30
Applicant: ERBER AKTIENGESELLSCHAFT
Inventor： Michaela Thamhesl , Sebastian Fruhauf , Wulf-Dieter Moll , Andreas Hoebartner , Gerd Schatzmayr , Eva Maria Binder , Markus Aleschko , Martin Pfeffer
IPC: C12N9/14 , A23K20/189 , A23K50/30 , A23K50/60 , A23K50/75 , A23L29/00 , A23L33/10 , A23L33/00 , A61K38/46
Abstract: The present invention relates to a method for increasing the stability of an α/β-hydrolase. In addition, the present invention relates to an α/β-hydrolase obtainable by the method of the present invention. Also provided are α/β-hydrolases having a decreased grand average of hydropathy (GRAVY) value and/or comprising specific mutations. In addition, the present invention concerns a use of an α/β-hydrolase of the present invention for degrading zearalenone (ZEN).
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公开(公告)号：US10779556B2
公开(公告)日：2020-09-22
申请号：US16161266
申请日：2018-10-16
Applicant: Erber Aktiengesellschaft
Inventor： Sebastian Fruhauf , Michaela Thamhesl , Martin Pfeffer , Dieter Moll , Gerd Schatzmayr , Eva Maria Binder
IPC: A23K10/14 , C12N9/14 , A23K50/75 , A23K50/30 , A23K50/80 , A23L3/3571 , C12N9/18 , C07K14/195
Abstract: The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.
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