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公开(公告)号：US06193686B1
公开(公告)日：2001-02-27
申请号：US09345664
申请日：1999-06-30
IPC分类号： A61M2900
CPC分类号： A61M25/104 , A61M25/007 , A61M25/0075 , A61M25/09 , A61M2025/0063 , A61M2025/0183 , A61M2025/1079 , A61M2025/1093
摘要： A balloon catheter system generally having an elongated catheter shaft with enhanced flexibility to facilitate more distal advancement within a patient's body lumen. The catheter shaft has a relatively stiff proximal shaft section, a relatively flexible distal shaft section and an intermediate shaft section which provides a smooth, flexible transition between the proximal and distal shaft sections. The intermediate shaft section has an improved construction with a tubular reinforcing member secured by its proximal end to the distal extremity of the proximal shaft section and a distal end secured within the proximal end of the distal shaft section. The tubular reinforcing member preferably has an inner tubular support member which has a proximal end secured to the distal end of the proximal shaft section. Preferably, the proximal shaft section has an outer jacket which extends over the tubular reinforcing member of the intermediate shaft section. Dual lumen and concentric distal shaft sections are describes. Additionally, over-the-wire constructions are described in which the inner and outer tubular members forming part of the distal shaft section extend the length of the catheter.
摘要翻译： 一种气囊导管系统，其通常具有细长的导管轴，该导管轴具有增强的柔性，以便于在患者的体腔内更远的前进。 导管轴具有相对刚性的近端轴部分，相对柔性的远侧轴部分和中间轴部分，其在近端和远端轴部分之间提供平滑的柔性过渡。 中间轴部分具有改进的构造，其中管状加强构件通过其近端固定到近侧轴部分的远端，并且远端固定在远侧轴部分的近端内。 管状加强构件优选地具有内管状支撑构件，其具有固定到近端轴部分的远端的近端。 优选地，近侧轴部分具有在中间轴部分的管状加强件上延伸的外护套。 描述双腔和同心远端轴段。 另外，描述了在线结构，其中形成远侧轴部分的一部分的内部和外部管状构件延伸导管的长度。
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公开(公告)号：US06695812B2
公开(公告)日：2004-02-24
申请号：US10005025
申请日：2001-12-04
IPC分类号： A61M2900
CPC分类号： A61M25/104 , A61M25/007 , A61M25/0075 , A61M25/09 , A61M2025/0063 , A61M2025/0183 , A61M2025/1079 , A61M2025/1093
摘要： A balloon catheter system generally having an elongated catheter shaft with enhanced flexibility to facilitate more distal advancement within a patient's body lumen. The catheter shaft has a relatively stiff proximal shaft section, a relatively flexible distal shaft section and an intermediate shaft section which provides a smooth, flexible transition between the proximal and distal shaft sections. The intermediate shaft section has an improved construction with a tubular reinforcing member secured by its proximal end to the distal extremity of the proximal shaft section and a distal end secured within the proximal end of the distal shaft section. The tubular reinforcing member preferably has an inner tubular support member which has a proximal end secured to the distal end of the proximal shaft section. Preferably, the proximal shaft section has an outer jacket which extends over the tubular reinforcing member of the intermediate shaft section. Dual lumen and concentric distal shaft sections are describes. Additionally, over-the-wire constructions are described in which the inner and outer tubular members forming part of the distal shaft section extend the length of the catheter.
摘要翻译： 一种气囊导管系统，其通常具有细长的导管轴，该导管轴具有增强的柔性，以便于在患者的体腔内更远的前进。 导管轴具有相对刚性的近端轴部分，相对柔性的远侧轴部分和中间轴部分，其在近端和远端轴部分之间提供平滑的柔性过渡。 中间轴部分具有改进的构造，其中管状加强构件通过其近端固定到近侧轴部分的远端，并且远端固定在远侧轴部分的近端内。 管状加强构件优选地具有内管状支撑构件，其具有固定到近端轴部分的远端的近端。 优选地，近侧轴部分具有在中间轴部分的管状加强件上延伸的外护套。 描述双腔和同心远端轴段。 另外，描述了在线结构，其中形成远侧轴部分的一部分的内部和外部管状构件延伸导管的长度。
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公开(公告)号：US06344029B1
公开(公告)日：2002-02-05
申请号：US09724733
申请日：2000-11-28
IPC分类号： A61M2900
CPC分类号： A61M25/104 , A61M25/007 , A61M25/0075 , A61M25/09 , A61M2025/0063 , A61M2025/0183 , A61M2025/1079 , A61M2025/1093
摘要： A balloon catheter system generally having an elongated catheter shaft with enhanced flexibility to facilitate more distal advancement within a patient's body lumen. The catheter shaft has a relatively stiff proximal shaft section, a relatively flexible distal shaft section and an intermediate shaft section which provides a smooth, flexible transition between the proximal and distal shaft sections. The intermediate shaft section has an improved construction with a tubular reinforcing member secured by its proximal end to the distal extremity of the proximal shaft section and a distal end secured within the proximal end of the distal shaft section. The tubular reinforcing member preferably has an inner tubular support member which has a proximal end secured to the distal end of the proximal shaft section. Preferably, the proximal shaft section has an outer jacket which extends over the tubular reinforcing member of the intermediate shaft section. Dual lumen and concentric distal shaft sections are describes. Additionally, over-the-wire constructions are described in which the inner and outer tubular members forming part of the distal shaft section extend the length of the catheter.
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公开(公告)号：US07147817B1
公开(公告)日：2006-12-12
申请号：US10335484
申请日：2002-12-31
CPC分类号： B29C61/006 , A61M25/0045 , A61M25/1006 , A61M25/1036 , A61M25/1038 , A61M25/104 , A61M2025/1031 , A61M2025/1075 , A61M2025/1081 , B29L2022/025 , B29L2031/7542
摘要： A method of making a catheter balloon or other expandable tubular medical device or component thereof, in which an assembly of heat shrink material on an outer surface of coaxially disposed first and second tubes is heated to radially shrink the heat shrink material and reduce the outer diameter of the first tube. In a presently preferred embodiment, the heat shrink material extends at least along a central section of the first tube to reduce the outer diameter of the first tube at least along the central section of the first tube. The first and second tubes form the outer and inner layers, respectively, of a multilayered balloon, which has an improved low profile outer diameter.
摘要翻译： 一种制造导管球囊或其它可扩张的管状医疗装置或其组件的方法，其中在同轴设置的第一和第二管的外表面上的热收缩材料的组件被加热以径向收缩热收缩材料并减小外径 的第一管。 在目前优选的实施例中，热收缩材料至少沿着第一管的中心部分延伸，以至少沿着第一管的中心部分减小第一管的外径。 第一和第二管分别形成多层气囊的外层和内层，其具有改进的低外形外径。
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公开(公告)号：US06946173B2
公开(公告)日：2005-09-20
申请号：US10103274
申请日：2002-03-21
申请人： Florencia Lim , Chi Le Long , Charles D. Claude , Jeong S. Lee , Srinivasan Sridharan , Fernando Gonzalez , Edwin Wang
发明人： Florencia Lim , Chi Le Long , Charles D. Claude , Jeong S. Lee , Srinivasan Sridharan , Fernando Gonzalez , Edwin Wang
IPC分类号： A61L29/00 , A61F2/958 , A61L29/04 , A61L29/08 , A61L29/12 , A61M25/00 , A61M25/16 , B32B1/08 , A61M25/10 , A61M29/00
CPC分类号： A61M25/1034 , A61L29/041 , A61L29/085 , A61L29/126 , A61M25/1006 , A61M25/1025 , A61M25/1029 , A61M2025/1075 , Y10T428/13 , Y10T428/1334 , Y10T428/1352 , Y10T428/1376 , Y10T428/1386 , Y10T428/139 , Y10T428/1393 , C08L27/18
摘要： A catheter balloon formed of a polymeric material such as expanded polytetrafluoroethylene (ePTFE) bonded to a second layer formed of a low tensile set polymer and/or impregnated with a low tensile set polymer. In a presently preferred embodiment, the low tensile set polymer is a silicone-polyurethane copolymer elastomer or a diene polymer elastomer. The low tensile set polymer has high strength, low modulus, high elongation, and low tensile set. The diene or silicone-polyurethane has a low tensile set, which facilitates deflation of the balloon to a low profile deflated configuration. One aspect of the invention provides improved attachment of the diene to the ePTFE. In one embodiment, the second layer is formed of a diene mixed with a bonding promoter such as a vulcanizing agent which is covalently bonded to the diene.
摘要翻译： 由诸如膨胀聚四氟乙烯（ePTFE）的聚合物材料形成的导管球囊结合到由低拉伸凝固聚合物形成的第二层和/或用低拉伸固化聚合物浸渍。 在目前优选的实施方案中，低拉伸固化聚合物是硅氧烷 - 聚氨酯共聚物弹性体或二烯聚合物弹性体。 低强度聚合物具有高强度，低模量，高伸长率和低拉伸强度。 二烯或硅氧烷聚氨酯具有低拉伸组合，其有利于将气囊放气至低剖面放气构型。 本发明的一个方面提供了改进的二烯与ePTFE的连接。 在一个实施方案中，第二层由与二烯混合的二烯混合形成，所述二烯与粘合促进剂例如硫化剂混合。
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公开(公告)号：US07892469B2
公开(公告)日：2011-02-22
申请号：US10802225
申请日：2004-03-16
申请人： Florencia Lim , NianJiong Bei , Chi Le Long
发明人： Florencia Lim , NianJiong Bei , Chi Le Long
CPC分类号： A61L29/049 , A61F2/958 , A61M25/1027 , A61M25/1029 , A61M25/104 , A61M29/02 , B29C47/00 , B29C47/0023 , B29C47/065 , B29C55/24 , B29K2075/00 , B29L2022/022 , B29L2031/7542
摘要： An intravascular catheter system for properly implanting a stent in a body lumen generally comprising a catheter having an elongated shaft with an inflatable balloon formed of compliant material and a stent mounted on the working length of the balloon. The balloon material is compliant within the working range of the balloon to provide substantial radial expansion. The wingless radially expansive balloon expands in a uniform manner, thereby producing uniform expansion and implantation of the stent. Another embodiment is directed to a balloon catheter, having a semi-compliant balloon or a noncompliant balloon formed at least in part of a block copolymer.
摘要翻译： 一种用于将支架适当地植入体腔内的血管内导管系统，其通常包括具有细长轴的导管，所述导管具有由顺应性材料形成的可膨胀气囊和安装在所述气囊的工作长度上的支架。 球囊材料在气球的工作范围内是柔顺的，以提供显着的径向膨胀。 无翼状径向膨胀气囊以均匀的方式膨胀，从而产生支架的均匀膨胀和植入。 另一个实施方案涉及一种球囊导管，其具有至少部分由嵌段共聚物形成的半顺应性气囊或不合适气囊。
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公开(公告)号：US06939321B2
公开(公告)日：2005-09-06
申请号：US10255487
申请日：2002-09-26
申请人： Edwin Wang , Florencia Lim , Huong Chung , Chi Le Long , Nadine Ding
发明人： Edwin Wang , Florencia Lim , Huong Chung , Chi Le Long , Nadine Ding
CPC分类号： A61M25/1034 , A61M25/10 , A61M25/1006 , A61M2025/1075 , Y10T428/1334
摘要： A balloon catheter and a method of making the balloon catheter, having a balloon which is bonded to an elongated shaft, and which has a first layer and a second layer and an improved strong bond between the balloon and the shaft. One aspect of the invention is directed to a balloon in which the balloon first layer has at least a section with a gas plasma-etched or chemical solution-etched surface for improved bondability. Another aspect of the invention is directed to a balloon in which the balloon first layer has a proximal end section bonded to an outer surface of the shaft and the balloon second layer has a proximal end section bonded to an inner surface of the shaft, and, in one embodiment, at least a section of the balloon first layer has a gas plasma-etched or chemical solution-etched surface.
摘要翻译： 气囊导管和制造气囊导管的方法，具有结合到细长轴的气球，并且具有第一层和第二层以及在球囊和轴之间改善的强结合。 本发明的一个方面涉及一种球囊，其中球囊第一层具有至少一个具有气体等离子体蚀刻或化学溶液蚀刻表面的部分，以提高粘合性。 本发明的另一方面涉及一种球囊，其中球囊第一层具有接合到轴的外表面的近端部分，球囊第二层具有接合到轴的内表面的近端部分， 在一个实施例中，气囊第一层的至少一部分具有气体等离子体蚀刻或化学溶液蚀刻表面。
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