Process and composition for oral hygiene
    3.
    发明授权
    Process and composition for oral hygiene 失效
    口腔卫生的过程和组成

    公开(公告)号:US5275804A

    公开(公告)日:1994-01-04

    申请号:US951354

    申请日:1992-09-25

    申请人: Edwin B. Michaels

    发明人: Edwin B. Michaels

    摘要: A process for enhancing oral hygiene by reducing oral microflora and for inhibiting the formation of dental plaque by applying, to the oral cavity a composition containing (a)0.1 to 40 parts, by weight, of a higher acyl-N-betaine having the structure ##STR1## where R is a higher alkyl group of from 10 to 18 carbon atoms, or mixtures thereof, and (b) 0.1 to 40 parts, by weight of a higher alkyl-N,-N-dimethylamine oxide, a higher alkyl-N-N-dihydroxyethylamine oxide, or an acyl-amino t-amine, of the respective structures: ##STR2##

    摘要翻译: 一种通过减少口腔微生物群落和抑制牙菌斑形成来增强口腔卫生的方法,所述方法是向所述口腔施用含有(a)0.1-40重量份的具有所述结构的较高级酰基-N-甜菜碱 (*化学结构*)(*化学结构*)其中R是10至18个碳原子的高级烷基或其混合物,和(b)0.1至40重量份的较高级烷基-N, - (*化学结构*)(*化学结构*)(*化学结构*)(*化学结构*)(*化学结构*)(*化学结构*)

    Process and composition for oral hygiene
    5.
    发明授权
    Process and composition for oral hygiene 失效
    口腔卫生的过程和组成

    公开(公告)号:US5403579A

    公开(公告)日:1995-04-04

    申请号:US136317

    申请日:1993-10-13

    申请人: Edwin B. Michaels

    发明人: Edwin B. Michaels

    摘要: A process for enhancing oral hygiene by reducing oral microflora and for inhibiting the formation of dental plaque in a subject by applying to the oral cavity a composition containing 0.1 to 40 parts, by weight, of a higher alkyl-N-sulfobetaine having the structure ##STR1## where R is a higher alkyl group of from 10 to 18 carbon atoms and b) 0.1 to 40 parts, by weight, of a higher alkyl-N,N-dimethylamine oxide, a higher alkyl-N,N-dihydroxylethylamine oxide, or an acylamide t-amine oxide having the respective structures: ##STR2## wherein R is a higher alkyl of from 10 to 18 carbon atoms, or mixtures of said amine oxides.

    摘要翻译: 一种通过向口腔施用减少口腔微生物群落和抑制牙菌斑形成来提高口腔卫生的方法,该组合物含有0.1-40重量份的具有结构<! - SIPO - >的高级烷基-N-磺基甜菜碱, 其中R是10至18个碳原子的高级烷基,b)0.1-40重量份的高级烷基-N,N-二甲基氧化胺,高级烷基-N,N-二羟基三乙胺氧化物, 或具有各自结构的酰胺叔胺氧化物,或者所述氧化胺的混合物。

    Process and composition for oral hygiene
    10.
    发明授权
    Process and composition for oral hygiene 失效
    口腔卫生的过程和组成

    公开(公告)号:US4839158A

    公开(公告)日:1989-06-13

    申请号:US81580

    申请日:1987-07-31

    申请人: Edwin B. Michaels

    发明人: Edwin B. Michaels

    IPC分类号: A61K8/40 A61K8/44 A61Q11/00

    摘要: A process for enhancing oral hygiene by reducing oral microflora and for inhibiting the formation of dental plaque by applying, to the oral cavity, a composition containing(a) 0.1 to 40 parts, by weight, of a higher alkyl-N-betaine, having the structure ##STR1## wherein N is a higher alkyl group of from 10-18 carbon atoms, and (b) 0.1 to 40 parts, by weight, of a higher alkyl-N, N-dimethylamine, having the structure ##STR2## wherein R is a higher alkyl group of from 10 to 18 carbon atoms, and (c) acid in an amount sufficient to adjust the pH of the composition from 4.5 to 7.5 when measured in an aqueous solution of components (a) and (b) in a orally acceptable carrier.

    摘要翻译: 一种通过减少口腔微生物群落和通过向口腔施用含有(a)0.1至40重量份的高级烷基-N-甜菜碱的组合物来增强口腔卫生的方法,所述高级烷基-N-甜菜碱具有 结构其中N是10-18个碳原子的高级烷基,和(b)0.1至40重量份的具有结构“IMAGE”的高级烷基-N,N-二甲胺,其中 R是10-18个碳原子的高级烷基,和(c)当在组分(a)和(b)的水溶液中测量时,足以将组合物的pH调节到4.5至7.5的量的酸 口头可接受的载体。