-
1.发明授权Antibiotic GE 2270 factors B.sub.1, B.sub.2, C.sub.1, C.sub.2, D.sub.1, D.sub.2, E and T 失效抗生素GE 2270因子B1，B2，C1，C2，D1，D2，E和T
公开(公告)号：US5747295A
公开(公告)日：1998-05-05
申请号：US460177
申请日：1995-06-02
IPC分类号： A61K31/44 , A61K38/00 , A61P3/00 , A61P31/00 , C07D513/22 , C07K5/078 , C12P17/18 , C12P21/04 , C12R1/01 , C12P1/00
CPC分类号： C07K5/06139 , A61K38/00
摘要： The present invention is directed to new antibiotic substances denominated antibiotic GE 2270 factors B.sub.1, B.sub.2, C.sub.1, C.sub.2, D.sub.1, D.sub.2, E and T, the addition salts thereof, the pharmaceutical compositions thereof and their use as medicaments, particularly in the treatment of infectious diseases involving microorganisms susceptible to them and their use as animal growth promoters.
摘要翻译： 本发明涉及新型抗生素物质GE 2270因子B1，B2，C1，C2，D1，D2，E和T，其加成盐，其药物组合物及其作为药物的用途，特别是用于治疗 涉及对它们敏感的微生物的感染性疾病及其作为动物生长促进剂的用途。
-
公开(公告)号：US5843890A
公开(公告)日：1998-12-01
申请号：US462997
申请日：1995-06-05
IPC分类号： A61K31/44 , A61K38/00 , A61P3/00 , A61P31/00 , C07D513/22 , C07K5/078 , C12P17/18 , C12P21/04 , C12R1/01 , A61K35/70
CPC分类号： C07K5/06139 , A61K38/00
摘要： The present invention is directed to new antibiotic substances denominated antibiotic GE 2270 factors B.sub.1, B.sub.2, C.sub.1, C.sub.2, D.sub.1, D.sub.2, E and T, the addition salts thereof, the pharmaceutical compositions thereof and their use as medicaments, particularly in the treatment of infectious diseases involving microorganisms susceptible to them and their use as animal growth promoters.
-
公开(公告)号：US5322777A
公开(公告)日：1994-06-21
申请号：US961007
申请日：1992-10-14
CPC分类号： C07K5/06139 , C12R1/01 , A61K38/00
摘要： The present invention is directed to a new antibiotic substance denominated antibiotic GE 2270, the addition salts thereof, the pharmaceutical compositions thereof and their use as medicaments, particularly in the treatment of infectious diseases involving microorganisms susceptible to them.
摘要翻译： 本发明涉及一种新型抗生素物质GE2270，其加成盐，其药物组合物及其作为药物的用途，特别是用于治疗涉及对其敏感的微生物的感染性疾病。
-
4.发明授权Method for selectively enhancing the production of factors A or B.sub.0 of antibiotic A 40926 complex 失效选择性增强抗生素A 40926复合物因子A或B0生成的方法
公开(公告)号：US5843679A
公开(公告)日：1998-12-01
申请号：US460024
申请日：1995-06-02
摘要： The present invention is directed to a method for selectively enhancing the production of factors A, and/or B.sub.0 of antibiotic A 40926 either to isolate these single components in better yields or to enrich the complex in one or both the above components, which comprises adding an appropriate precursor of the desired antibiotic factor to an A 40926 producing culture during fermentation.
摘要翻译： 本发明涉及一种用于选择性增强抗生素A 40926的因子A和/或B0的产生的方法，以便以更好的产率分离这些单一组分或富集上述组分的一种或两种中的复合物，其包括加入 在发酵期间产生A 40926的培养物的所需抗生素因子的合适前体。
-
公开(公告)号：US5610143A
公开(公告)日：1997-03-11
申请号：US493043
申请日：1995-06-21
申请人： Sergio Stella , Nicoletta Montanini , Francis J. LeMonnier , Luigi Colombo , Enrico Selva , Maurizio Denaro
发明人： Sergio Stella , Nicoletta Montanini , Francis J. LeMonnier , Luigi Colombo , Enrico Selva , Maurizio Denaro
CPC分类号： C07K5/0821 , A23K20/195 , C07K5/06139 , C12R1/465 , A61K38/00
摘要： The present invention is directed to new antibiotic substances denominated antibiotics GE 37468 A, B and C, their addition salts with bases, the pharmaceutical compositions thereof and their use as medicaments, particularly in the treatment of infectious diseases involving microorganisms susceptible to them.The compounds of the invention are also active as growth promotant agents in animals, such as poultry, swine, ruminants, etc.
-
公开(公告)号：US5567676A
公开(公告)日：1996-10-22
申请号：US457365
申请日：1995-06-01
申请人： Enrico Selva , Grazia Beretta , Angelo Borghi , Maurizio Denaro
发明人： Enrico Selva , Grazia Beretta , Angelo Borghi , Maurizio Denaro
IPC分类号： C12P21/02 , A61K38/00 , A61P31/04 , C07G11/00 , C07K20060101 , C07K9/00 , C07K14/195 , C07K14/41 , C12R1/045 , A61K38/14 , A61K38/12
CPC分类号： C07K9/008
摘要： The present invention concerns new antiobiotic substances demoninated de-acyl antibiotics A40926, de-acyl antibiotic A 40926P and antibiotic A 40926 amino glucronyl aglycon, and the use of these substances in the treatment of infectious diseases involving microorganisms susceptible to it.
摘要翻译： 本发明涉及脱酰基抗生素A40926，去酰基抗生素A40926P和抗生素A40926氨基葡糖苷酸苷的新抗生素物质，以及这些物质用于治疗涉及对其敏感的微生物的感染性疾病的用途。
-
公开(公告)号：US5618724A
公开(公告)日：1997-04-08
申请号：US648646
申请日：1996-05-16
申请人： Sergio Stella , Nicoletta Montanini , Francis J. LeMonnier , Luigi Colombo , Enrico Selva , Maurizio Denaro
发明人： Sergio Stella , Nicoletta Montanini , Francis J. LeMonnier , Luigi Colombo , Enrico Selva , Maurizio Denaro
IPC分类号： A23K20/195 , A61K38/00 , C07K5/078 , C07K5/097 , C12M1/02
CPC分类号： C07K5/0821 , A23K20/195 , C07K5/06139 , C12R1/465 , A61K38/00
摘要： The present invention is directed to new antibiotic substances denominated antibiotics GE 37468 A, B and C, their addition salts with bases, the pharmaceutical compositions thereof and their use as medicaments, particularly in the treatment of infectious diseases involving microorganisms susceptible to them.The compounds of the invention are also active as growth promotant agents in animals, such as poultry, swine, ruminants, etc.
摘要翻译： 本发明涉及新的抗生素物质GE 37468A，B和C，它们与碱的加成盐，其药物组合物及其作为药物的用途，特别是用于治疗涉及对它们敏感的微生物的感染性疾病。 本发明的化合物在动物如动物，如家禽，猪，反刍动物等中也是有活性的。
-
公开(公告)号：US5606036A
公开(公告)日：1997-02-25
申请号：US447152
申请日：1995-05-22
申请人： Rolf H. Hermann , Romeo Ciabatti , Enrico Selva , Maurizio Denaro
发明人： Rolf H. Hermann , Romeo Ciabatti , Enrico Selva , Maurizio Denaro
CPC分类号： C07K9/008
摘要： The present invention relates to novel ester derivatives of antibiotic A 40926 complex and its N-acylaminoglucuronyl aglycone. The compounds of the invention are prepared according to an esterification process involving reaction of an A 40926 substrate with an excess of the selected alkanol in the presence of concentrated mineral acid and are reactive as antibiotics.
摘要翻译： 本发明涉及抗生素A40926复合物的新型酯衍生物及其N-酰氨基葡萄糖醛酸糖苷配基。 本发明的化合物根据酯化方法制备，该方法包括在浓无机酸存在下A404026底物与过量的选择的链烷醇的反应，并作为抗生素反应。
-
公开(公告)号：US5514649A
公开(公告)日：1996-05-07
申请号：US428787
申请日：1995-04-21
申请人： Enrico Selva , Sergio Stella , Luigi Colombo , Maurizio Denaro
发明人： Enrico Selva , Sergio Stella , Luigi Colombo , Maurizio Denaro
IPC分类号： A61K31/435 , A61K38/00 , A61P31/00 , C07D513/22 , C07G11/00 , C07K5/078 , C12P1/06 , C12R1/01 , C07K5/00 , A61K35/00 , C07K7/00
CPC分类号： C07K5/06139 , A61K38/00
摘要： The present invention is directed to a new antibiotic substance denominated antibiotic GE 2270 factor C.sub.2a, the addition salts thereof, the pharmaceutical compositions thereof and its use as medicament, particularly in the treatment of infectious diseases involving microorganisms susceptible to it and its use as animal growth promoter.
摘要翻译： 本发明涉及一种新型抗生素物质GE 2270因子C2a，其加成盐，其药物组合物及其作为药物的用途，特别是用于治疗涉及对其敏感的微生物的感染性疾病及其作为动物生长的用途 启动子。
-
公开(公告)号：US5202241A
公开(公告)日：1993-04-13
申请号：US713567
申请日：1991-06-11
CPC分类号： C07K5/06139 , C12R1/01 , A61K38/00
摘要： The present invention is directed to a new antibiotic substance denominated antibiotic GE 2270, the addition salts thereof, the pharmaceutical compositions thereof and their use as medicaments, particularly in the treatment of infectious diseases involving microorganisms susceptible to them.
摘要翻译： 本发明涉及一种新型抗生素物质GE2270，其加成盐，其药物组合物及其作为药物的用途，特别是用于治疗涉及对其敏感的微生物的感染性疾病。
-
-
-
-
-
-
-
-
-
搜索结果
19 条记录 (耗时 0.04 秒)
