Integrated tail mounted blood pressure monitor and pulse oximeter system for animal research
    3.
    发明授权
    Integrated tail mounted blood pressure monitor and pulse oximeter system for animal research 有权
    综合尾装血压计和脉搏血氧仪系统进行动物研究

    公开(公告)号:US07857768B2

    公开(公告)日:2010-12-28

    申请号:US12249044

    申请日:2008-10-10

    摘要: An integrated tail mounted blood pressure monitor and pulse oximeter system includes a tail blood flow occlusion member configured to selectively occlude blood flow through the tail; a sensor coupled to the tail blood flow occlusion member detecting a degree of operation thereof; Light sources coupled to the tail closer to the distal end of the tail than the tail blood flow occlusion member, and selectively directing light of two different wavelengths into the tail; a light receiver coupled to the tail and selectively receiving a signal associated with light directed into the tail from the light sources; and a controller configured to selectively determine blood pressure parameters from the data and pulse oximeter parameters from the data.

    摘要翻译: 综合的尾部安装的血压监测器和脉搏血氧计系统包括构造成选择性地阻塞穿过尾部的血流的尾部血流阻塞构件; 耦合到所述尾部血流阻塞构件的传感器,其检测其操作程度; 耦合到尾部的光源比尾部血流阻塞构件更靠近尾部的远端,并且选择性地将两种不同波长的光引导到尾部中; 耦合到尾部的光接收器并且选择性地接收与从光源引导到尾部中的光相关联的信号; 以及控制器,被配置为从数据中选择性地从数据和脉搏血氧计参数确定血压参数。

    Noninvasive photoplethysmographic sensor platform for mobile animals
    4.
    发明授权
    Noninvasive photoplethysmographic sensor platform for mobile animals 有权
    用于移动动物的无创光电体积描记传感器平台

    公开(公告)号:US08688184B2

    公开(公告)日:2014-04-01

    申请号:US12330501

    申请日:2008-12-08

    IPC分类号: A61B5/00

    CPC分类号: A61B5/14552 A61B2503/40

    摘要: A noninvasive photoplethysmographic sensor platform for mobile animals such as small rodents, namely rats and mice is useful such as in a laboratory research environment. The noninvasive photoplethysmographic sensor platform may be a collar which provides an easily affixed, adjustable attachment mechanism that encircles the animal, such as the neck. The neck of the animal provides several particular advantages as a sensor mounting platform for photoplethysmographic sensors. For pulse oximetry, the neck location will provide significant blood flow under all conditions. For small mammals, such as rats and mice, transmittance pulse oximetry through the neck of the subject remains possible. The neck mounted collar also offers inherent bite resistance to the sensor platform.

    摘要翻译: 用于诸如小鼠和小鼠的移动动物的无创光电体积描记传感器平台是有用的,例如在实验室研究环境中。 无创光电体积描记传感器平台可以是一个套环,提供一个环绕动物(如颈部)的容易固定的可调节的附接机构。 作为光电容积传感器的传感器安装平台,动物的颈部提供了几个特殊的优点。 对于脉搏血氧饱和度测量,颈部位置将在所有条件下提供显着的血流量。 对于小型哺乳动物,如大鼠和小鼠,穿过受试者颈部的透射脉搏血氧饱和度仍然是可能的。 颈部安装的衣领还为传感器平台提供了固有的抗咬伤性。

    Intraoral electromuscular stimulation device and method
    5.
    发明授权
    Intraoral electromuscular stimulation device and method 失效
    口内电磁刺激装置及方法

    公开(公告)号:US07711438B2

    公开(公告)日:2010-05-04

    申请号:US10623328

    申请日:2003-07-18

    IPC分类号: A61N1/05

    CPC分类号: A61N1/0548 A61N1/3601

    摘要: An intraoral electromuscular stimulation device and method to treat a breathing disorder. The stimulation device includes a first electrode, a first support member that maintains the first electrode in a sublingual location posterior to a frenulum and proximate to one of a first molar, a second molar and a third molar of a patient. A second electrode is maintained in a sublingual position posterior relative to the first electrode by a second support member. A further embodiment of the stimulation device includes a sensor that detects a respiratory parameter of a patient and outputs a signal indicative thereof. A control unit receives the signal from the sensor, distinguishes between inspiration and expiration, and initiates an electrical stimulation at a stimulation time prior to onset of inspiration and continues stimulation through a portion of inspiration at a level sufficient to induce muscle contraction without pain.

    摘要翻译: 口内电磁刺激装置及治疗呼吸障碍的方法。 所述刺激装置包括第一电极,第一支撑构件,所述第一支撑构件将所述第一电极保持在手术后的舌下位置,并且靠近患者的第一摩尔,第二摩尔和第三磨牙中的一个。 第二电极通过第二支撑构件保持在相对于第一电极后方的舌下位置。 刺激装置的另一实施例包括检测患者的呼吸参数并输出指示其的信号的传感器。 控制单元接收来自传感器的信号,区分吸气和呼气,并且在启动开始之前的刺激时间开始电刺激,并且通过一部分吸气继续刺激足以引起肌肉收缩而没有疼痛的水平。

    Method and apparatus for determining cardiac output
    6.
    发明授权
    Method and apparatus for determining cardiac output 失效
    用于确定心输出量的方法和装置

    公开(公告)号:US07367954B2

    公开(公告)日:2008-05-06

    申请号:US10763971

    申请日:2004-01-23

    IPC分类号: A61B5/08 A61B5/02

    CPC分类号: A61B5/029 A61B5/0833

    摘要: A method and apparatus for use in determining the cardiac output. The method includes measuring a first parameter indicative of a patient's oxygen uptake and a second parameter indicative of the patient's fractional arterial oxygen concentration. The method also includes inducing a change in the patient's arterial oxygen concentration while taking these measurements to monitor the effects of the change in the patient's arterial oxygen concentration. The cardiac output is determined from the data collected regarding the effects of the change in the patient's arterial oxygen concentration.

    摘要翻译: 一种用于确定心输出量的方法和装置。 该方法包括测量指示患者氧吸收的第一参数和指示患者分数动脉氧浓度的第二参数。 该方法还包括诱导患者动脉氧浓度的变化,同时进行这些测量以监测患者动脉氧浓度变化的影响。 从收集的关于患者动脉氧浓度变化的影响的数据中确定心输出量。