-
公开(公告)号：US08808622B2
公开(公告)日：2014-08-19
申请号：US13194351
申请日：2011-07-29
申请人： Ernst V. Arnold , Blaine G. Doletski , Thomas M. Dunn , Robert E. Raulli , Edward P. Mueller , Karen R. Benedek , Marie-Louise Murville
发明人： Ernst V. Arnold , Blaine G. Doletski , Thomas M. Dunn , Robert E. Raulli , Edward P. Mueller , Karen R. Benedek , Marie-Louise Murville
CPC分类号： A61L2/20 , A61L2/00 , A61L2/0094 , A61L2/16 , A61L2202/122 , A61L2202/24
摘要： A system, device and method for sterilizing or decontaminating an object that by exposing the object to a sterilant gas comprised of one or more oxides of nitrogen, such as NO, NO2, NO3, N2O3, N2O4, N2O5, N2O and mixtures thereof. The source of the sterilant gas can be generated from a sterilant gas-generating composition or provided by a source of the sterilant gas.
摘要翻译： 将物体暴露于由一种或多种氮氧化物（如NO，NO 2，NO 3，N 2 O 3，N 2 O 4，N 2 O 5，N 2 O）及其混合物构成的杀菌剂气体的灭菌或去污的系统，装置和方法。 杀菌剂气体的来源可以由消毒剂产生气体的组合物产生，或由灭菌气体的来源提供。
-
公开(公告)号：US20110059036A1
公开(公告)日：2011-03-10
申请号：US12940208
申请日：2010-11-05
CPC分类号： C08F8/30 , A61K31/655 , A61L27/34 , A61L29/085 , A61L31/10 , C08G63/6854 , C08G64/12
摘要： This invention relates to compositions comprising carbon-based diazeniumdiolates attached to hydrophobic polymers that releases nitric oxide (NO). The carbon-based diazeniumdiolated polymers release NO spontaneously under physiological conditions without subsequence nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated polymers, compositions comprising such polymers, methods of using such compositions, and devices employing such polymer compositions.
摘要翻译： 本发明涉及包含与释放一氧化氮（NO）的疏水性聚合物连接的碳基二氮烯二硫醇盐的组合物。 碳基二氮茚二聚物在生理条件下自发释放NO，而不产生亚硝胺形成。 本发明还涉及制备碳基二氮烯二烯聚合物的方法，包含这种聚合物的组合物，使用这种组合物的方法，以及使用这种聚合物组合物的装置。
-
公开(公告)号：US07569559B2
公开(公告)日：2009-08-04
申请号：US11052745
申请日：2005-02-09
IPC分类号： C07C245/00 , A61K31/655
CPC分类号： A61K31/655
摘要： This invention relates to compositions comprising carbon-based diazeniumdiolates that release nitric oxide (NO). The carbon-based diazeniumdiolated molecules release NO spontaneously under physiological conditions without subsequent nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated molecules, compositions comprising such molecules, methods of using such compositions, and devices employing such molecule compositions.
摘要翻译： 本发明涉及包含释放一氧化氮（NO）的碳基二氮烯二硫醇盐的组合物。 碳基二氮茚二酮分子在生理条件下自发释放NO，无后续的亚硝胺形成。 本发明还涉及制备碳基二氮茚二酮分子的方法，包含这种分子的组合物，使用这种组合物的方法，以及使用这种分子组合物的装置。
-
公开(公告)号：US08894985B2
公开(公告)日：2014-11-25
申请号：US12940208
申请日：2010-11-05
IPC分类号： A61P9/08 , C08G63/685 , A61K31/655 , A61L31/10 , A61L29/08 , A61L27/34 , C08G64/12 , C08F8/30
CPC分类号： C08F8/30 , A61K31/655 , A61L27/34 , A61L29/085 , A61L31/10 , C08G63/6854 , C08G64/12
摘要： This invention relates to compositions comprising carbon-based diazeniumdiolates attached to hydrophobic polymers that releases nitric oxide (NO). The carbon-based diazeniumdiolated polymers release NO spontaneously under physiological conditions without subsequence nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated polymers, compositions comprising such polymers, methods of using such compositions, and devices employing such polymer compositions.
摘要翻译： 本发明涉及包含与释放一氧化氮（NO）的疏水性聚合物连接的碳基二氮烯二硫醇盐的组合物。 碳基二氮茚二聚物在生理条件下自发释放NO，而不产生亚硝胺形成。 本发明还涉及制备碳基二氮烯二烯聚合物的方法，包含这种聚合物的组合物，使用这种组合物的方法，以及使用这种聚合物组合物的装置。
-
公开(公告)号：US20110318225A1
公开(公告)日：2011-12-29
申请号：US13194351
申请日：2011-07-29
申请人： Ernst V. ARNOLD , Blaine G. Doletski , Thomas M. Dunn , Robert E. Raulli , Edward P. Mueller , Karen R. Benedek , Marie-Louise Murville
发明人： Ernst V. ARNOLD , Blaine G. Doletski , Thomas M. Dunn , Robert E. Raulli , Edward P. Mueller , Karen R. Benedek , Marie-Louise Murville
IPC分类号： A61L2/20
CPC分类号： A61L2/20 , A61L2/00 , A61L2/0094 , A61L2/16 , A61L2202/122 , A61L2202/24
摘要： A system, device and method for sterilizing or decontaminating an object that by exposing the object to a sterilant gas comprised of one or more oxides of nitrogen, such as NO, NO2, NO3, N2O3, N2O4, N2O5, N2O and mixtures thereof. The source of the sterilant gas can be generated from a sterilant gas-generating composition or provided by a source of the sterilant gas.
摘要翻译： 将物体暴露于由一种或多种氮氧化物（如NO，NO 2，NO 3，N 2 O 3，N 2 O 4，N 2 O 5，N 2 O）及其混合物构成的杀菌剂气体的灭菌或去污的系统，装置和方法。 杀菌剂气体的来源可以由消毒剂产生气体的组合物产生，或由灭菌气体的来源提供。
-
公开(公告)号：US20090270509A1
公开(公告)日：2009-10-29
申请号：US12497113
申请日：2009-07-02
IPC分类号： A61K31/04 , C07C241/00 , A01N1/02
CPC分类号： A61K31/655
摘要： This invention relates to compositions comprising carbon-based diazeniumdiolates that release nitric oxide (NO). The carbon-based diazeniumdiolated molecules release NO spontaneously under physiological conditions without subsequent nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated molecules, compositions comprising such molecules, methods of using such compositions, and devices employing such molecule compositions.
摘要翻译： 本发明涉及包含释放一氧化氮（NO）的碳基二氮烯二硫醇盐的组合物。 碳基二氮茚二酮分子在生理条件下自发释放NO，无后续的亚硝胺形成。 本发明还涉及制备碳基二氮茚二酮分子的方法，包含这种分子的组合物，使用这种组合物的方法，以及使用这种分子组合物的装置。
-
公开(公告)号：US08101589B2
公开(公告)日：2012-01-24
申请号：US12497113
申请日：2009-07-02
IPC分类号： A61K31/655 , C07C245/00
CPC分类号： A61K31/655
摘要： This invention relates to compositions comprising carbon-based diazeniumdiolates that release nitric oxide (NO). The carbon-based diazeniumdiolated molecules release NO spontaneously under physiological conditions without subsequent nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated molecules, compositions comprising such molecules, methods of using such compositions, and devices employing such molecule compositions.
摘要翻译： 本发明涉及包含释放一氧化氮（NO）的碳基二氮烯二硫醇盐的组合物。 碳基二氮茚二酮分子在生理条件下自发释放NO，无后续的亚硝胺形成。 本发明还涉及制备碳基二氮茚二酮分子的方法，包含这种分子的组合物，使用这种组合物的方法，以及使用这种分子组合物的装置。
-
公开(公告)号：US08017074B2
公开(公告)日：2011-09-13
申请号：US11477513
申请日：2006-06-30
申请人： Ernst V. Arnold , Blaine G. Doletski , Thomas M. Dunn , Robert E. Raulli , Edward P. Mueller , Karen R. Benedek , Marie-Louise Murville
发明人： Ernst V. Arnold , Blaine G. Doletski , Thomas M. Dunn , Robert E. Raulli , Edward P. Mueller , Karen R. Benedek , Marie-Louise Murville
CPC分类号： A61L2/20 , A61L2/00 , A61L2/0094 , A61L2/16 , A61L2202/122 , A61L2202/24
摘要： A system, device and method for sterilizing or decontaminating an object that by exposing the object to a sterilant gas comprised of one or more oxides of nitrogen, such as NO, NO2, NO3, N2O3, N2O4, N2O5, N2O and mixtures thereof. The source of the sterilant gas can be generated from a sterilant gas-generating composition or provided by a source of the sterilant gas.
摘要翻译： 将物体暴露于由一种或多种氮氧化物（如NO，NO 2，NO 3，N 2 O 3，N 2 O 4，N 2 O 5，N 2 O）及其混合物构成的杀菌剂气体的灭菌或去污的系统，装置和方法。 杀菌剂气体的来源可以由消毒剂产生气体的组合物产生，或由灭菌气体的来源提供。
-
公开(公告)号：US07829553B2
公开(公告)日：2010-11-09
申请号：US10588718
申请日：2005-01-06
IPC分类号： A61K31/655
CPC分类号： C08F8/30 , A61K31/655 , A61L27/34 , A61L29/085 , A61L31/10 , C08G63/6854 , C08G64/12
摘要： This invention relates to compositions comprising carbon-based diazeniumdiolates attached to hydrophobic polymers that releases nitric oxide (NO). The carbon-based diazeniumdiolated polymers release NO spontaneously under physiological conditions without subsequent nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated polymers, compositions comprising such polymers, methods of using such compositions, and devices employing such polymer compositions.
摘要翻译： 本发明涉及包含与释放一氧化氮（NO）的疏水性聚合物连接的碳基二氮烯二硫醇盐的组合物。 碳基二氮茚二聚物在生理条件下自发释放NO，无后续的亚硝胺形成。 本发明还涉及制备碳基二氮烯二烯聚合物的方法，包含这种聚合物的组合物，使用这种组合物的方法，以及使用这种聚合物组合物的装置。
-
10.发明申请公开(公告)号：US20100255062A1
公开(公告)日：2010-10-07
申请号：US12602198
申请日：2008-06-02
申请人： Aristotle G. Kalivretenos , Robert E. Raulli , Niaz Sahibzada , Richard Gillis , Mark S. Niedringhaus
发明人： Aristotle G. Kalivretenos , Robert E. Raulli , Niaz Sahibzada , Richard Gillis , Mark S. Niedringhaus
CPC分类号： A61K49/001 , A61K31/785 , A61K47/58
摘要： The present disclosure describes novel carbon-based diazeniumdiolates agents and compounds or salts or prodrugs thereof that release nitric oxide for the treatment of neuropathic gastrointestinal dysfunction. The neuropathic gastrointestinal dysfunction refers to disorders associated with motility, sensation and neuromuscular function that include but are not limited to conditions such as delayed gastric emptying.
摘要翻译： 本公开描述了新型的碳基二氮烯鎓二硫醇盐试剂及其释放一氧化氮以用于治疗神经性胃肠功能障碍的化合物或其盐或前药。 神经性胃肠功能障碍是指与运动，感觉和神经肌肉功能相关的障碍，包括但不限于诸如延迟胃排空的病症。
-
-
-
-
-
-
-
-
-
搜索结果
10 条记录 (耗时 0.024 秒)
