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公开(公告)号：US20130302842A1
公开(公告)日：2013-11-14
申请号：US13467584
申请日：2012-05-09
CPC分类号： G01N33/5005 , A01N1/0263 , A01N1/0268 , B01L3/502715 , B01L7/50 , B01L2200/027 , B01L2300/044 , B01L2300/047 , B01L2300/0672 , B01L2300/0816 , B01L2300/0887 , B01L2400/0406 , B01L2400/0481 , B01L2400/0677 , B01L2400/0683 , B01L2400/0694 , B01L2400/086
摘要： A microfluidic device and method is provided for handheld diagnostics and assays. A first substance is frozen in a cryopreservation fluid in a first well of a lid. The lid includes a first surface communicating with a first port of the first well and a second surface communicating with a second port of the first well. A porous membrane is affixed to the first surface so as to overlap the first port and a non-porous membrane is affixed to the second surface so as to overlap the second port. The first substance may be dialytically freed from the cryopreservation fluid at a user desired time. Thereafter, the lid may be moved from a first position wherein the lid is spaced from a base to a second position wherein the lid is adjacent the channel in the base such that the first substance communicates with the input of the channel.
摘要翻译： 提供了用于手持诊断和测定的微流体装置和方法。 将第一物质在盖的第一孔中的冷冻保存液中冷冻。 所述盖包括与所述第一井的第一端口连通的第一表面和与所述第一井的第二端口连通的第二表面。 将多孔膜固定在第一表面上以与第一端口重叠，并且非多孔膜固定到第二表面以与第二端口重叠。 第一物质可以在用户期望的时间透析地从冷冻保存液中除去。 此后，盖可以从第一位置移动，其中盖子与基座间隔开到第二位置，其中盖子与基座中的通道相邻，使得第一物质与通道的输入端相通。
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公开(公告)号：US20130302817A1
公开(公告)日：2013-11-14
申请号：US13467544
申请日：2012-05-09
CPC分类号： B01L3/502715 , B01L3/5023 , B01L3/50853 , B01L2200/027 , B01L2300/044 , B01L2300/047 , B01L2300/0672 , B01L2300/0816 , B01L2400/0406 , B01L2400/0481 , B01L2400/0677 , B01L2400/0683 , B01L2400/086
摘要： A microfluidic device and method is provided for handheld diagnostics and assays. The device includes a base having outer surface and a channel therethough for receiving fluid therein. The channel has input and output ports communicating with the outer surface. A lid is also provided. The lid has an outer surface, a first well having a port communicating with the outer surface of the lid, and a second well having a port communicating with the outer surface. The lid moveable between a first disengaged position and a second engaged position wherein the first port of the lid is adjacent the input port of the channel and the second port is adjacent the output port of the channel.
摘要翻译： 提供了用于手持诊断和测定的微流体装置和方法。 该装置包括具有外表面的基部和用于在其中接收流体的通道。 通道具有与外表面连通的输入和输出端口。 还提供盖子。 盖具有外表面，第一阱具有与盖的外表面连通的端口，以及具有与外表面连通的端口的第二阱。 所述盖可在第一脱离位置和第二接合位置之间移动，其中所述盖的第一端口邻近所述通道的输入端口，并且所述第二端口邻近所述通道的输出端口。
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公开(公告)号：US09283559B2
公开(公告)日：2016-03-15
申请号：US13467584
申请日：2012-05-09
CPC分类号： G01N33/5005 , A01N1/0263 , A01N1/0268 , B01L3/502715 , B01L7/50 , B01L2200/027 , B01L2300/044 , B01L2300/047 , B01L2300/0672 , B01L2300/0816 , B01L2300/0887 , B01L2400/0406 , B01L2400/0481 , B01L2400/0677 , B01L2400/0683 , B01L2400/0694 , B01L2400/086
摘要： A microfluidic device and method is provided for handheld diagnostics and assays. A first substance is frozen in a cryopreservation fluid in a first well of a lid. The lid includes a first surface communicating with a first port of the first well and a second surface communicating with a second port of the first well. A porous membrane is affixed to the first surface so as to overlap the first port and a non-porous membrane is affixed to the second surface so as to overlap the second port. The first substance may be dialytically freed from the cryopreservation fluid at a user desired time. Thereafter, the lid may be moved from a first position wherein the lid is spaced from a base to a second position wherein the lid is adjacent the channel in the base such that the first substance communicates with the input of the channel.
摘要翻译： 提供了用于手持诊断和测定的微流体装置和方法。 将第一物质在盖的第一孔中的冷冻保存液中冷冻。 所述盖包括与所述第一井的第一端口连通的第一表面和与所述第一井的第二端口连通的第二表面。 将多孔膜固定在第一表面上以与第一端口重叠，并且非多孔膜固定到第二表面以与第二端口重叠。 第一物质可以在用户期望的时间透析地从冷冻保存液中除去。 此后，盖可以从第一位置移动，其中盖子与基座间隔开到第二位置，其中盖子与基座中的通道相邻，使得第一物质与通道的输入端相通。
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公开(公告)号：US09186670B2
公开(公告)日：2015-11-17
申请号：US13467544
申请日：2012-05-09
IPC分类号： B01L3/00
CPC分类号： B01L3/502715 , B01L3/5023 , B01L3/50853 , B01L2200/027 , B01L2300/044 , B01L2300/047 , B01L2300/0672 , B01L2300/0816 , B01L2400/0406 , B01L2400/0481 , B01L2400/0677 , B01L2400/0683 , B01L2400/086
摘要： A microfluidic device and method is provided for handheld diagnostics and assays. The device includes a base having outer surface and a channel therethough for receiving fluid therein. The channel has input and output ports communicating with the outer surface. A lid is also provided. The lid has an outer surface, a first well having a port communicating with the outer surface of the lid, and a second well having a port communicating with the outer surface. The lid moveable between a first disengaged position and a second engaged position wherein the first port of the lid is adjacent the input port of the channel and the second port is adjacent the output port of the channel.
摘要翻译： 提供了用于手持诊断和测定的微流体装置和方法。 该装置包括具有外表面的基部和用于在其中接收流体的通道。 通道具有与外表面连通的输入和输出端口。 还提供盖子。 盖具有外表面，第一阱具有与盖的外表面连通的端口，以及具有与外表面连通的端口的第二阱。 所述盖可在第一脱离位置和第二接合位置之间移动，其中所述盖的第一端口邻近所述通道的输入端口，并且所述第二端口邻近所述通道的输出端口。
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公开(公告)号：US11430279B2
公开(公告)日：2022-08-30
申请号：US13467599
申请日：2012-05-09
摘要： A microfluidic platform and method are provided. The microfluidic platform includes a base having an outer surface and a plurality of wells formed in the outer surface thereof for receiving fluid therein. The plurality of wells are in fluid communication with each other. A lid includes a plurality of channels having corresponding inputs and outputs. The lid is moveable between a first position wherein the lid is disengaged from the base and a second position wherein the inputs of each channel communicate with corresponding wells in the base. The fluid in each well is drawn into corresponding channels through the inputs thereof by capillary action.
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公开(公告)号：US20130299041A1
公开(公告)日：2013-11-14
申请号：US13467599
申请日：2012-05-09
CPC分类号： G07C9/00134 , B01L3/0255 , B01L3/0262 , B01L3/0293 , B01L3/50273 , B01L3/563 , B01L2200/16 , B01L2300/047 , B01L2300/0672 , B01L2300/0816 , B01L2400/024 , B01L2400/0406 , B01L2400/0481 , B01L2400/0683 , G07C9/00166 , G07C2209/08
摘要： A microfluidic platform and method are provided. The microfluidic platform includes a base having an outer surface and a plurality of wells formed in the outer surface thereof for receiving fluid therein. The plurality of wells are in fluid communication with each other. A lid includes a plurality of channels having corresponding inputs and outputs. The lid is moveable between a first position wherein the lid is disengaged from the base and a second position wherein the inputs of each channel communicate with corresponding wells in the base. The fluid in each well is drawn into corresponding channels through the inputs thereof by capillary action.
摘要翻译： 提供微流体平台和方法。 微流体平台包括具有外表面的基部和在其外表面中形成的用于在其中接收流体的多个阱。 多个井彼此流体连通。 盖包括具有相应输入和输出的多个通道。 盖子可以在其中盖子与基座脱开的第一位置和第二位置之间移动，第二位置，每个通道的输入端与基座中的相应的孔连通。 每个孔中的流体通过其通过毛细作用的输入被吸入相应的通道。
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