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公开(公告)号：US20160009785A1
公开(公告)日：2016-01-14
申请号：US14440569
申请日：2013-11-05
Applicant: FOUNDATION MEDICINE, INC.
Inventor： Doron Lipson , Roman Yelensky , Joel Robert Greenbowe , Jie He
CPC classification number: C07K14/71 , C07K14/47 , C07K16/18 , C07K16/2863 , C07K16/40 , C12N9/96 , C12N15/62
Abstract: Novel fusion molecules and uses are disclosed.
Abstract translation: 公开了新颖的融合分子和用途。
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公开(公告)号：US20150366866A1
公开(公告)日：2015-12-24
申请号：US14761518
申请日：2014-01-17
Applicant: Vincent A. Miller , FOUNDATION MEDICINE, INC.
Inventor： Siraj Mahamed Ali , Matthew J. Hawryluk , Jie He , Doron Lipson , Vincent A. Miller , Jeffrey S. Ross , Philip James Stephens
IPC: A61K31/5025 , C07K16/40 , C12Q1/68 , G01N33/573 , C12N9/12 , A61K31/4412 , C12N15/113
CPC classification number: A61K31/5025 , A61K31/404 , A61K31/435 , A61K31/4412 , A61K31/4439 , A61K31/47 , A61K31/496 , A61K31/498 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/53 , A61K31/5383 , A61K31/553 , A61K45/06 , C07K14/705 , C07K14/71 , C07K16/40 , C07K2319/00 , C12N9/12 , C12N15/1137 , C12N2310/11 , C12N2310/12 , C12N2310/14 , C12Q1/6883 , C12Q1/6886 , C12Q2600/156 , C12Q2600/158 , C12Y207/10001 , G01N33/573 , G01N2333/912 , G01N2500/04
Abstract: Methods and compositions for treating cholangiocarcinoma.
Abstract translation: 治疗胆管癌的方法和组合物。
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Patent Agency Ranking
公开(公告)号：US11230589B2
公开(公告)日：2022-01-25
申请号：US14440569
申请日：2013-11-05
Applicant: FOUNDATION MEDICINE, INC.
Inventor： Doron Lipson , Roman Yelensky , Joel Robert Greenbowe , Jie He
Abstract: Novel fusion molecules and uses are disclosed.
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公开(公告)号：US10980804B2
公开(公告)日：2021-04-20
申请号：US14761518
申请日：2014-01-17
Applicant: FOUNDATION MEDICINE, INC.
Inventor： Siraj Mahamed Ali , Matthew J. Hawryluk , Jie He , Doron Lipson , Vincent A. Miller , Jeffrey S. Ross , Philip James Stephens
IPC: A61K31/517 , A61K31/498 , A61K31/19 , A61K31/5025 , C12N9/12 , A61K31/4412 , A61K45/06 , A61K31/47 , A61K31/435 , A61K31/506 , A61K31/519 , A61K31/4439 , A61K31/53 , A61K31/404 , A61K31/5383 , A61K31/496 , C12Q1/6886 , A61K31/553 , C07K14/705 , C07K14/71 , C07K16/40 , C12N15/113 , C12Q1/6883 , G01N33/573
Abstract: Methods and compositions for treating cholangiocarcinoma.
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公开(公告)号：US12274699B2
公开(公告)日：2025-04-15
申请号：US18346029
申请日：2023-06-30
Applicant: Foundation Medicine, Inc.
Inventor： Siraj Mahamed Ali , Matthew J. Hawryluk , Jie He , Doron Lipson , Vincent A. Miller , Jeffrey S. Ross , Philip James Stephens
IPC: A61K31/517 , A61K31/19 , A61K31/404 , A61K31/435 , A61K31/4412 , A61K31/4439 , A61K31/47 , A61K31/496 , A61K31/498 , A61K31/5025 , A61K31/506 , A61K31/519 , A61K31/53 , A61K31/5383 , A61K31/553 , A61K45/06 , C07K14/705 , C07K14/71 , C07K16/40 , C12N9/12 , C12N15/113 , C12Q1/6883 , C12Q1/6886 , G01N33/573
Abstract: Methods and compositions for treating cholangiocarcinoma.
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公开(公告)号：US11674962B2
公开(公告)日：2023-06-13
申请号：US16041363
申请日：2018-07-20
Applicant: Genentech, Inc. , Foundation Medicine, Inc.
Inventor： Craig Anthony Cummings , Yan Li , Sarah Margaret Shagan , Erica Beth Schleifman , David Shames , David Fabrizio , Daniel Lieber , Geoffrey Alan Otto , Mark Kennedy , Travis Clark , Doron Lipson , Jie He , Shan Zhong
IPC: C12Q1/68 , C12Q1/6883 , G01N33/574 , C07K16/28 , G16H50/50 , G16H50/30 , G16H50/70 , G16H50/20 , A61P35/00 , G06F16/28 , C07K14/735 , A61K39/00
CPC classification number: G01N33/574 , A61P35/00 , C07K14/70535 , C07K16/2827 , C07K16/2896 , C12Q1/68 , C12Q1/6883 , G01N33/57492 , G06F16/285 , G16H50/20 , G16H50/30 , G16H50/50 , G16H50/70 , A61K2039/505 , A61K2039/55 , C07K2317/24 , C12Q2600/156 , G01N2333/70532 , G01N2800/52
Abstract: The present invention provides therapeutic, diagnostic, and prognostic methods for cancer. The invention provides methods of treating a cancer, methods of determining whether an individual having a cancer is likely to respond to a treatment including an immune checkpoint inhibitor (e.g., a PD-L1 axis binding antagonist), methods of predicting responsiveness of an individual having a cancer to a treatment including an immune checkpoint inhibitor (e.g., a PD-L1 axis binding antagonist), methods of selecting a therapy for an individual having a cancer, methods of providing a prognosis for an individual having a cancer, and methods of monitoring a response of an individual having a cancer, based on a blood tumor mutational burden (bTMB) score or a maximum somatic allele frequency (MSAF) from a sample (e.g., a whole blood sample, a plasma sample, a serum sample, or a combination thereof) from the individual.
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公开(公告)号：US11771698B2
公开(公告)日：2023-10-03
申请号：US17204830
申请日：2021-03-17
Applicant: Foundation Medicine, Inc.
Inventor： Siraj Mahamed Ali , Matthew J. Hawryluk , Jie He , Doron Lipson , Vincent A. Miller , Jeffrey S. Ross , Philip James Stephens
IPC: A61K31/517 , A61K31/498 , A61K31/19 , A61K31/5025 , C12N9/12 , A61K31/4412 , A61K45/06 , A61K31/47 , A61K31/435 , A61K31/506 , A61K31/519 , A61K31/4439 , A61K31/53 , A61K31/404 , A61K31/5383 , A61K31/496 , C12Q1/6886 , A61K31/553 , C07K14/705 , C07K14/71 , C07K16/40 , C12N15/113 , C12Q1/6883 , G01N33/573
CPC classification number: A61K31/5025 , A61K31/404 , A61K31/435 , A61K31/4412 , A61K31/4439 , A61K31/47 , A61K31/496 , A61K31/498 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/53 , A61K31/5383 , A61K31/553 , A61K45/06 , C07K14/705 , C07K14/71 , C07K16/40 , C12N9/12 , C12N15/1137 , C12Q1/6883 , C12Q1/6886 , C12Y207/10001 , G01N33/573 , C07K2319/00 , C12N2310/11 , C12N2310/12 , C12N2310/14 , C12Q2600/156 , C12Q2600/158 , G01N2333/912 , G01N2500/04
Abstract: Methods and compositions for treating cholangiocarcinoma.
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