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Patent Agency Ranking
公开(公告)号：US11007678B2
公开(公告)日：2021-05-18
申请号：US15933573
申请日：2018-03-23
Applicant: FUJIFILM Corporation
Inventor： Shotaro Ogawa , Satoshi Chai , Kenji Ichikawa , Kazunori Komatsu , Kozue Ikeda , Ryo Hibino
IPC: B29C33/38 , B29C33/42 , B81C99/00 , A61M37/00 , B29C43/52 , B29C33/40 , B29C41/20 , B29C41/38 , B29C41/42 , C25D1/10 , B29K101/12 , B29L7/00 , B29L31/00
Abstract: A production method of a mold includes: preparing a plate precursor having a protruding pattern formed of protrusions in a pattern presence region on a base, and a thermoplastic resin sheet; determining a position at which the plate precursor is to be pressed against the thermoplastic resin sheet by moving the plate precursor and the thermoplastic resin sheet relative to each other; and forming a recessed pattern on the thermoplastic resin sheet by pressing the protrusions of the plate precursor which is heated against the thermoplastic resin sheet at a position where a part of the pattern presence region of the plate precursor excluding the protrusions is separated from a surface of the thermoplastic resin sheet, cooling the plate precursor in a state in where the pressed protrusions and the thermoplastic resin sheet are in contact with each other, and separating the plate precursor from the thermoplastic resin sheet.
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公开(公告)号：US11597122B2
公开(公告)日：2023-03-07
申请号：US16591634
申请日：2019-10-03
Applicant: FUJIFILM Corporation
Inventor： Ricardo Itiro Ori , Hiroki Yanagawa , Kozue Ikeda
Abstract: Provided are a manufacturing method of a plate precursor having a plurality of needle-like protrusions and a manufacturing method of a microneedle array, which make it possible to manufacture a plate precursor within a short period of time.
A manufacturing method of a plate precursor having a needle-like protrusion includes: a preparation step of preparing a cutting tool including at least one blade conforming to an external shape of the needle-like protrusion, and a base material; and a cutting step of cutting the base material by rotating the cutting tool about a tool axis of the cutting tool and revolving the cutting tool around an axis of the needle-like protrusion to be formed on the base material to form the needle-like protrusion having a shape conforming to a shape of the cutting tool.-
公开(公告)号：US11772305B2
公开(公告)日：2023-10-03
申请号：US18049643
申请日：2022-10-26
Applicant: FUJIFILM Corporation
Inventor： Aya Mochizuki , Satoshi Chai , Toshihiro Usa , Kozue Ikeda
CPC classification number: B29C33/3857 , A61M37/0015 , B29C33/3842 , B29C33/40 , A61M2037/0053 , B29C33/424 , B29C2033/426
Abstract: A production method of a mold having a recessed pattern includes: a plate precursor preparation step of preparing a plate precursor having a pedestal on which a protruding pattern is disposed; a resin plate preparation step of preparing a thermoplastic resin plate having a recessed step portion; and a resin plate precursor production step of producing a thermoplastic resin plate precursor. The plate precursor comprises a substrate having a larger area than the pedestal in a plan view on a side opposite to a surface of the pedestal on which the protruding pattern is disposed. An edge portion where a side surface of the pedestal and the substrate are in contact with each other has a through-hole penetrating the substrate along the side surface of the pedestal.
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公开(公告)号：US11534943B2
公开(公告)日：2022-12-27
申请号：US16807181
申请日：2020-03-03
Applicant: FUJIFILM Corporation
Inventor： Aya Mochizuki , Satoshi Chai , Toshihiro Usa , Kozue Ikeda
Abstract: A production method of a mold having a recessed pattern includes: a plate precursor preparation step of preparing a plate precursor having a pedestal on which a protruding pattern is disposed; a resin plate preparation step of preparing a thermoplastic resin plate having a recessed step portion; and a resin plate precursor production step of producing a thermoplastic resin plate precursor, the resin plate precursor production step including a positioning step of positioning the protruding pattern of the plate precursor and a center position of the recessed step portion, and a recessed pattern forming step of forming a recessed pattern having an inverted shape of the protruding pattern on the thermoplastic resin plate by pressing the protruding pattern of the heated plate precursor and the pedestal against the recessed step portion, thereafter cooling the plate precursor, and separating the plate precursor from the thermoplastic resin plate.
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公开(公告)号：US20220324141A1
公开(公告)日：2022-10-13
申请号：US17849097
申请日：2022-06-24
Applicant: FUJIFILM Corporation
Inventor： Toshihiro Usa , Yasuhiro Sekizawa , Kenichiro Tamaki , Satoshi Chai , Kozue Ikeda
Abstract: Provided is a method for manufacturing a microneedle array, which enables efficient and stable manufacturing of a microneedle array including a needle-shaped protrusion having a constricted shape. The method for manufacturing a microneedle array includes: a first cutting step of forming a needle-shaped protrusion by cutting a base material by a first cutting tool; a second cutting step of forming a constricted shape in the needle-shaped protrusion by cutting a part of the needle-shaped protrusion by a second cutting tool different from the first cutting tool; a mold forming step of molding, from a plate precursor manufactured through the first cutting step and the second cutting step, a resin mold having a needle-shaped hole which has an inverted shape of the plate precursor; a first array manufacturing step of filling the needle-shaped hole of the resin mold with a drug solution and then drying the drug solution; a second array manufacturing step of filling the needle-shaped hole with a base material solution and drying the base material solution, after the first array manufacturing step; and a peeling step of peeling, from the resin mold, a microneedle array manufactured by the resin mold.
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