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    DETECTION USING A DYE AND A DYE MODIFIER
    6.
    发明申请
    DETECTION USING A DYE AND A DYE MODIFIER 有权
    使用染色剂和染色体改性剂进行检测

    公开(公告)号：US20120282617A1

    公开(公告)日：2012-11-08

    申请号：US13413352

    申请日：2012-03-06

    申请人： Fei Mao ,  Wai-Yee Leung ,  Hye Eun Hoover

    发明人： Fei Mao ,  Wai-Yee Leung ,  Hye Eun Hoover

    IPC分类号： G01N21/64

    CPC分类号： C09B67/0033 ,  C09B69/02 ,  Y10T436/143333

    摘要： The present invention relates to dyes in general. The present invention provides a wide range of dyes and kits containing the same, which are applicable for labeling a variety of biomolecules such as nucleic acids, cells and microorganisms. The present invention also provides various methods of using the dyes for research and development, forensic identification, environmental studies, diagnosis, prognosis, and/or treatment of disease conditions.

    摘要翻译： 本发明一般涉及染料。 本发明提供了广泛的含有该染料和试剂盒的染料和试剂盒，其适用于标记各种生物分子如核酸，细胞和微生物。 本发明还提供了用于研究和开发，法医鉴定，环境研究，诊断，预后和/或治疗疾病状况的各种方法。

    Detection using a dye and a dye modifier
    7.
    发明授权
    Detection using a dye and a dye modifier 有权
    使用染料和染料改性剂进行检测

    公开(公告)号：US08148515B1

    公开(公告)日：2012-04-03

    申请号：US12792718

    申请日：2010-06-02

    申请人： Fei Mao ,  Wai-Yee Leung ,  Hye Eun Hoover

    发明人： Fei Mao ,  Wai-Yee Leung ,  Hye Eun Hoover

    IPC分类号： C07H21/00

    CPC分类号： C09B67/0033 ,  C09B69/02 ,  Y10T436/143333

    摘要： The present invention relates to dyes in general. The present invention provides a wide range of dyes and kits containing the same, which are applicable for labeling a variety of biomolecules such as nucleic acids, cells and microorganisms. The present invention also provides various methods of using the dyes for research and development, forensic identification, environmental studies, diagnosis, prognosis, and/or treatment of disease conditions.

    摘要翻译： 本发明一般涉及染料。 本发明提供了广泛的含有该染料和试剂盒的染料和试剂盒，其适用于标记各种生物分子如核酸，细胞和微生物。 本发明还提供了用于研究和开发，法医鉴定，环境研究，诊断，预后和/或治疗疾病状况的各种方法。

    Detection using a dye and a dye modifier
    9.
    发明授权
    Detection using a dye and a dye modifier 有权
    使用染料和染料改性剂进行检测

    公开(公告)号：US08524503B2

    公开(公告)日：2013-09-03

    申请号：US13413352

    申请日：2012-03-06

    申请人： Fei Mao ,  Hye Eun Hoover ,  Wai-Yee Leung

    发明人： Fei Mao ,  Hye Eun Hoover ,  Wai-Yee Leung

    IPC分类号： G01N33/00

    CPC分类号： C09B67/0033 ,  C09B69/02 ,  Y10T436/143333

    摘要： The present invention relates to dyes in general. The present invention provides a wide range of dyes and kits containing the same, which are applicable for labeling a variety of biomolecules such as nucleic acids, cells and microorganisms. The present invention also provides various methods of using the dyes for research and development, forensic identification, environmental studies, diagnosis, prognosis, and/or treatment of disease conditions.

    摘要翻译： 本发明一般涉及染料。 本发明提供了广泛的含有该染料和试剂盒的染料和试剂盒，其适用于标记各种生物分子如核酸，细胞和微生物。 本发明还提供了用于研究和开发，法医鉴定，环境研究，诊断，预后和/或治疗疾病状况的各种方法。

    Substituted anthraquinone dyes for cellular stains and enzyme detection
    10.
    发明授权
    Substituted anthraquinone dyes for cellular stains and enzyme detection 有权
    取代的蒽醌染料用于细胞染色和酶检测

    公开(公告)号：US08790892B2

    公开(公告)日：2014-07-29

    申请号：US13439821

    申请日：2012-04-04

    申请人： Fei Mao ,  Wai-Yee Leung ,  Ching-Ying Cheung ,  Lori Michelle Roberts

    发明人： Fei Mao ,  Wai-Yee Leung ,  Ching-Ying Cheung ,  Lori Michelle Roberts

    IPC分类号： G01N1/30

    CPC分类号： C09B1/516 ,  A61K49/0052 ,  C09B1/501 ,  C09B1/51 ,  C09B1/5155 ,  G01N1/30 ,  G01N21/6428

    摘要： The invention discloses new substituted anthraquinone dyes that may be useful as cellular stains. In some aspect of the invention, the nuclear stains are useful for staining the nuclei of dead or fixed cells. Another aspect of the invention relates to substituted anthraquinone dyes comprising an enzyme substrate moiety that is transformable or cleavable by an enzyme such that the transformation or cleavage of the substrate moiety causes a detectable change in the functionality or spectral properties of the dye.

    摘要翻译： 本发明公开了可用作细胞污渍的新的取代的蒽醌染料。 在本发明的某些方面，核染料可用于染色死细胞或固定细胞的细胞核。 本发明的另一方面涉及包含酶底物部分的取代的蒽醌染料，其可由酶转化或切割，使得底物部分的转化或切割导致染料的官能度或光谱性质的可检测变化。