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公开(公告)号:US20120202806A1
公开(公告)日:2012-08-09
申请号:US13391712
申请日:2010-08-31
申请人: Franz Dürrenberger , Susanna Burckhardt , Peter O. Geisser , Wilm Buhr , Felix Funk , Julia M. Bainbridge , Vincent A. Corden , Stephen M. Courtney , Tara Davenport , Stefan Jaeger , Mark P. Ridgill , Mark Slack , Christopher J. Yarnold , Wei Tsung Yau
发明人: Franz Dürrenberger , Susanna Burckhardt , Peter O. Geisser , Wilm Buhr , Felix Funk , Julia M. Bainbridge , Vincent A. Corden , Stephen M. Courtney , Tara Davenport , Stefan Jaeger , Mark P. Ridgill , Mark Slack , Christopher J. Yarnold , Wei Tsung Yau
IPC分类号: A61K31/5377 , A61P3/02 , A61P7/06 , A61K31/506
CPC分类号: C07D401/04 , C07D239/47 , C07D251/18 , C07D251/66 , C07D401/14 , C07D403/04
摘要: The present invention relates to new hepcidin antagonists, pharmaceutical compositions containing them and the use thereof as a drug, in particular for the treatment of iron metabolism disorders such as, in particular, iron deficiency diseases and anaemia, in particular anaemia associated with chronic inflammatory disease (ACD: anaemia of chronic disease and AI: anaemia of inflammation).
摘要翻译: 本发明涉及新的hepcidin拮抗剂,含有它们的药物组合物及其作为药物的用途,特别是用于治疗铁代谢紊乱,特别是铁缺乏症和贫血,特别是与慢性炎性疾病相关的贫血 (ACD:慢性病贫血和AI:炎症性贫血)。
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公开(公告)号:US20120214798A1
公开(公告)日:2012-08-23
申请号:US13394201
申请日:2010-09-06
申请人: Franz Dürrenberger , Susanna Burckhardt , Wilm Buhr , Peter O. Geisser , Felix Funk , Vincent A. Corden , Stephen M. Courtney , Tara Davenport , Stefan Jaeger , Mark P. Ridgill , Mark Slack , Christopher J. Yarnold , Wei Tsung Yau
发明人: Franz Dürrenberger , Susanna Burckhardt , Wilm Buhr , Peter O. Geisser , Felix Funk , Vincent A. Corden , Stephen M. Courtney , Tara Davenport , Stefan Jaeger , Mark P. Ridgill , Mark Slack , Christopher J. Yarnold , Wei Tsung Yau
IPC分类号: A61K31/497 , A61K31/5377 , A61P3/02 , A61K31/445 , A61K31/551 , A61K31/496 , A61K31/4545
CPC分类号: C07D401/12 , C07D211/14 , C07D211/58 , C07D211/62 , C07D213/38 , C07D239/42 , C07D241/20 , C07D295/13 , C07D307/24 , C07D405/12 , C07D405/14 , C07D409/12
摘要: The present invention relates to novel hepcidin antagonists of formula (I), pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for treatment of disorders in iron metabolism, such as, in particular, iron deficiency diseases and anaemias, in particular anaemias in connection with chronic inflammatory diseases (ACD: anaemia of chronic disease and AI: anaemia of inflammation).
摘要翻译: 本发明涉及式(I)的新颖的铁调素拮抗剂,包含它们的药物组合物及其作为药物的用途,特别是用于治疗铁代谢紊乱,特别是铁缺乏症和疾病,特别是贫血 与慢性炎性疾病有关(ACD:慢性病贫血和AI:炎症性贫血)。
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公开(公告)号:US20120196853A1
公开(公告)日:2012-08-02
申请号:US13390785
申请日:2010-08-19
申请人: Franz Dürrenberger , Susanna Burckhardt , Peter O. Geisser , Wilm Buhr , Felix Funk , Vincent A. Corden , Tara Davenport , Stefan Jaeger , Mark Slack , Christopher J. Yarnold , Wei Tsung Yau , Stephen M. Courtney
发明人: Franz Dürrenberger , Susanna Burckhardt , Peter O. Geisser , Wilm Buhr , Felix Funk , Vincent A. Corden , Tara Davenport , Stefan Jaeger , Mark Slack , Christopher J. Yarnold , Wei Tsung Yau , Stephen M. Courtney
IPC分类号: A61K31/5377 , A61K31/496 , A61P3/00 , A61P7/06 , A61P19/02 , A61P13/12 , A61P9/00 , A61P29/00 , A61P19/04 , A61P1/00 , A61K31/4709 , A61P35/00
CPC分类号: C07D215/28 , C07D215/26 , C07D215/32 , C07D401/06 , C07D401/14 , C07D405/06 , C07D409/06
摘要: The present invention relates to novel hepcidin antagonists of the general formula (I), pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for treatment of disorders in iron metabolism, such as, in particular, iron deficiency diseases and anaemias, in particular anaemias in connection with chronic inflammatory diseases (ACD: anaemia of chronic disease and AI: anaemia of inflammation).
摘要翻译: 本发明涉及通式(I)的新型铁调素拮抗剂,包含它们的药物组合物及其作为药物的用途,特别是用于治疗铁代谢紊乱,特别是铁缺乏症和厌食症 与慢性炎症性疾病有关的特异性厌食症(ACD:慢性疾病和AI:炎症性贫血)。
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公开(公告)号:US20120214803A1
公开(公告)日:2012-08-23
申请号:US13364566
申请日:2012-02-02
申请人: Wilm Buhr , Susanna Burckhardt , Franz Dürrenberger , Felix Funk , Peter O. Geisser , Vincent A. Corden , Stephen M. Courtney , Graham Dawson , Tara Davenport , Mark Slack , Mark P. Ridgill , Chrostopher J. Yarnold , Susan Boyce , Albertus A. Ellenbroek
发明人: Wilm Buhr , Susanna Burckhardt , Franz Dürrenberger , Felix Funk , Peter O. Geisser , Vincent A. Corden , Stephen M. Courtney , Graham Dawson , Tara Davenport , Mark Slack , Mark P. Ridgill , Chrostopher J. Yarnold , Susan Boyce , Albertus A. Ellenbroek
IPC分类号: A61K31/542 , C07D215/40 , C07D215/50 , C07D401/12 , C07D215/46 , A61P7/06 , A61K31/4706 , A61K31/4709 , A61K31/549 , A61K31/497 , A61P3/00 , C07D513/04 , C07D215/42
CPC分类号: C07D513/04 , A61K45/06 , C07D215/40 , C07D215/42 , C07D215/46 , C07D215/50 , C07D333/34 , C07D401/12 , C07D409/12 , C07D417/12
摘要: The present invention relates to novel hepcidin antagonists, pharmaceutical compositions comprising them and the use thereof as medicaments for the use in the treatment of iron metabolism disorders, such as, in particular, iron deficiency diseases and anemias, in particular anemias in connection with chronic inflammatory diseases.
摘要翻译: 本发明涉及新型的铁调素拮抗剂,包含它们的药物组合物及其作为用于治疗铁代谢紊乱的药物的用途,特别是铁缺乏症和贫血,特别是与慢性炎症有关的贫血 疾病
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公开(公告)号:US20120052135A1
公开(公告)日:2012-03-01
申请号:US13202586
申请日:2010-03-01
申请人: Gisela Witzel , Peter O. Geisser , Erik Philipp
发明人: Gisela Witzel , Peter O. Geisser , Erik Philipp
CPC分类号: A61K33/06 , A61K33/10 , A61K33/26 , A61K2300/00
摘要: Subject of the present invention are compositions comprising a mixture of calcium, magnesium and iron salts for use as a pharmaceutical preparation for adsorbing phosphate, especially for use as pharmaceutical preparations for the treatment of hyperphosphataemia, chronic kidney deficiency as well as for the treatment of haemodialysis patients.
摘要翻译: 本发明的主题是包含用于吸附磷酸盐的药物制剂的钙,镁和铁盐的混合物的组合物,特别是用作治疗高磷酸血症的药物制剂,慢性肾脏缺乏以及用于治疗血液透析 耐心。
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