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Patent Agency Ranking
公开(公告)号：US20150141353A1
公开(公告)日：2015-05-21
申请号：US14513900
申请日：2014-10-14
Applicant: GILEAD SCIENCES, INC.
Inventor： William E. Delaney, IV , John O. Link , Hongmei Mo , David W. Oldach , Adrian S. Ray , William J. Watkins , Cheng Yong Yang , Weidong Zhong
IPC: A61K31/4184 , A61K31/381 , A61K31/5377 , A61K31/501 , A61K31/706 , A61K31/675
CPC classification number: A61K38/05 , A61K31/381 , A61K31/40 , A61K31/401 , A61K31/4025 , A61K31/407 , A61K31/4178 , A61K31/4184 , A61K31/4188 , A61K31/4353 , A61K31/4436 , A61K31/501 , A61K31/5377 , A61K31/662 , A61K31/675 , A61K31/7056 , A61K31/706 , A61K31/7068 , A61K38/212 , A61K45/06 , A61K2300/00
Abstract: This invention relates to combinations of therapeutic molecules useful for treating hepatitis C virus infection. The present invention relates to methods, uses, dosing regimens, and compositions.
Abstract translation: 本发明涉及可用于治疗丙型肝炎病毒感染的治疗分子的组合。 本发明涉及方法，用途，给药方案和组合物。
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公开(公告)号：US09353423B2
公开(公告)日：2016-05-31
申请号：US14073488
申请日：2013-11-06
Applicant: Gilead Sciences, Inc.
Inventor： Guofeng Cheng , William E. Delaney, IV , Betty Peng , Mei Yu
IPC: C12Q1/70 , C07K16/00 , C07K14/005 , C07K16/10 , C12N7/00
CPC classification number: C12Q1/707 , C07K14/005 , C07K16/10 , C12N7/00 , C12N2770/24221 , C12N2770/24222 , C12N2770/24251
Abstract: Replicons of genotype 6 hepatitis C virus (HCV) are provided. These replicons contain adaptive mutations giving rise to the HCV's capability to replicate in vitro. Methods of preparing genotype 6 replicons and methods of using these replicons to screen antiviral agents are also provided.
Abstract translation: 提供了基因型6丙型肝炎病毒（HCV）的复制品。 这些复制子包含适应性突变，导致HCV在体外复制的能力。 还提供了制备基因型6复制子的方法和使用这些复制子筛选抗病毒剂的方法。
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公开(公告)号：US20170042961A1
公开(公告)日：2017-02-16
申请号：US15244926
申请日：2016-08-23
Applicant: Gilead Sciences, Inc.
Inventor： William E. Delaney, IV , John O. Link , Hongmei Mo , David W. Oldach , Adrian S. Ray , William J. Watkins , Cheng Yong Yang , Weidong Zhong
IPC: A61K38/05 , A61K31/675 , A61K31/7068 , A61K31/381 , A61K31/4184 , A61K31/501 , A61K31/706
CPC classification number: A61K38/05 , A61K31/381 , A61K31/40 , A61K31/401 , A61K31/4025 , A61K31/407 , A61K31/4178 , A61K31/4184 , A61K31/4188 , A61K31/4353 , A61K31/4436 , A61K31/501 , A61K31/5377 , A61K31/662 , A61K31/675 , A61K31/7056 , A61K31/706 , A61K31/7068 , A61K38/212 , A61K45/06 , A61K2300/00
Abstract: This invention relates to combinations of therapeutic molecules useful for treating hepatitis C virus infection. The present invention relates to methods, uses, dosing regimens, and compositions.
Abstract translation: 本发明涉及可用于治疗丙型肝炎病毒感染的治疗分子的组合。 本发明涉及方法，用途，给药方案和组合物。
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公开(公告)号：US09452154B2
公开(公告)日：2016-09-27
申请号：US14513900
申请日：2014-10-14
Applicant: Gilead Sciences, Inc.
Inventor： William E. Delaney, IV , John O. Link , Hongmei Mo , David W. Oldach , Adrian S. Ray , William J. Watkins , Cheng Yong Yang , Weidong Zhong
IPC: A61K31/675 , A61K31/4184 , A61K31/381 , A61K31/40 , A61K31/401 , A61K31/4025 , A61K31/407 , A61K31/4178 , A61K31/4188 , A61K31/4353 , A61K31/4436 , A61K31/662 , A61K31/7056 , A61K45/06 , A61K31/501 , A61K31/5377 , A61K38/21 , A61K31/706
CPC classification number: A61K38/05 , A61K31/381 , A61K31/40 , A61K31/401 , A61K31/4025 , A61K31/407 , A61K31/4178 , A61K31/4184 , A61K31/4188 , A61K31/4353 , A61K31/4436 , A61K31/501 , A61K31/5377 , A61K31/662 , A61K31/675 , A61K31/7056 , A61K31/706 , A61K31/7068 , A61K38/212 , A61K45/06 , A61K2300/00
Abstract: This invention relates to combinations of therapeutic molecules useful for treating hepatitis C virus infection. The present invention relates to methods, uses, dosing regimens, and compositions.
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公开(公告)号：US20140134604A1
公开(公告)日：2014-05-15
申请号：US14073488
申请日：2013-11-06
Applicant: Gilead Sciences, Inc.
Inventor： Guofeng Cheng , William E. Delaney, IV , Betty Peng , Mei Yu
IPC: C12Q1/70 , C07K16/10 , C07K14/005
CPC classification number: C12Q1/707 , C07K14/005 , C07K16/10 , C12N7/00 , C12N2770/24221 , C12N2770/24222 , C12N2770/24251
Abstract: Replicons of genotype 6 hepatitis C virus (HCV) are provided. These replicons contain adaptive mutations giving rise to the HCV's capability to replicate in vitro. Methods of preparing genotype 6 replicons and methods of using these replicons to screen antiviral agents are also provided.
Abstract translation: 提供了基因型6丙型肝炎病毒（HCV）的复制品。 这些复制子包含适应性突变，导致HCV在体外复制的能力。 还提供了制备基因型6复制子的方法和使用这些复制子筛选抗病毒剂的方法。
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