公开(公告)号：US20180160950A1

公开(公告)日：2018-06-14

申请号：US15578505

申请日：2016-06-02

Applicant: GIVEN IMAGING LTD.

Inventor： Elisha RABINOVITZ ,  Osnat SELLA-TAVOR ,  Amit PASCAL

IPC: A61B5/145 ,  A61B5/01 ,  A61B5/05 ,  A61B5/07 ,  A61B5/1486

CPC classification number: A61B5/14507 ,  A61B5/01 ,  A61B5/05 ,  A61B5/073 ,  A61B5/14503 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/14865 ,  A61B5/4216 ,  A61B5/6861 ,  A61B2562/0295 ,  A61B2562/162 ,  A61B2562/166 ,  G01N33/558

Abstract: A swallowable in-vivo device comprising a shell formed with at least one inlet extending across a shell wall and configured for allowing ingress of fluid at least into the shell; the shell accommodates therein a lateral flow (LF) arrangement configured for absorbing the fluid; the LF arrangement comprises a test zone configured for coming into contact, in-vivo, with a predetermined N substance present in the fluid or a compound comprising the substance, thereby causing a change in at least one property of the test zone; the shell further accommodates a sensor configured for sensing, in-vivo, the at least one property, at least when changed by interaction with the fluid; the LF arrangement has at least one curved segment, and at least one exposure portion juxtaposed with the inlet, configured for absorbing the fluid passing through the inlet into the shell.

公开(公告)号：US20140316222A1

公开(公告)日：2014-10-23

申请号：US14259946

申请日：2014-04-23

Applicant: GIVEN IMAGING LTD.

Inventor： Elisha RABINOVITZ ,  Osnat Sella-Tavor

IPC: A61B5/07 ,  A61B5/053 ,  A61B5/00

CPC classification number: A61B5/073 ,  A61B5/0084 ,  A61B5/0538 ,  A61B5/42 ,  A61B5/742

Abstract: Device, system and method for in-vivo detection of H. pylori. For example, an in-vivo device includes a housing, a reference electrode disposed on the housing, and a working electrode disposed on the housing in close proximity to the reference electrode. The working electrode is coated by litography or screen printing with salt such that substantially no current passes between the working electrode and the reference electrode. The in-vivo device further includes a measuring device for measuring current, impedance, and/or resistance between the working and the reference electrodes, and a transmitter for transmitting the measurements. Presence of ammonia, which is a byproduct of H. pylori, causes increase in current and thus decrease in impedance or resistance between the reference electrode and the working electrode; thereby measurements of current, impedance, and/or resistance indicate on presence or absence of H. pylori.

Abstract translation: 用于幽门螺杆菌体内检测的装置，系统和方法。 例如，体内装置包括壳体，设置在壳体上的参考电极，以及设置在紧靠参考电极的壳体上的工作电极。 工作电极通过带有盐的扫描或丝网印刷进行涂覆，使得工作电极和参比电极之间基本上没有电流通过。 体内装置还包括用于测量工作和参考电极之间的电流，阻抗和/或电阻的测量装置，以及用于传送测量的发射器。 作为幽门螺杆菌的副产物的氨的存在导致电流增加，从而降低参考电极和工作电极之间的阻抗或电阻; 因此，电流，阻抗和/或电阻的测量指示幽门螺杆菌存在或不存在时。

公开(公告)号：US20130204086A1

公开(公告)日：2013-08-08

申请号：US13803693

申请日：2013-03-14

Applicant: GIVEN IMAGING LTD.

Inventor： Elisha RABINOVITZ ,  Daniel GAT ,  Shirrie Rosenthal

IPC: A61M37/00 ,  A61B1/31 ,  A61B5/00 ,  A61B1/04

CPC classification number: A61M37/00 ,  A61B1/041 ,  A61B1/31 ,  A61B5/0084 ,  A61B5/6861 ,  A61M31/002

Abstract: An in vivo sensing device and system may contain or be used in conjunction with an image sensor and a body lumen clearing element or agent. A method may enable clearing a body lumen for in vivo sensing while using the device of the invention.

Abstract translation: 体内感测装置和系统可以包含或与图像传感器和体腔清洁元件或代理结合使用。 一种方法可以使得在使用本发明的装置的同时清除体腔以进行体内感测。