-
公开(公告)号：US20240383949A1
公开(公告)日：2024-11-21
申请号：US18435026
申请日：2024-02-07
Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
Inventor： Enrico MALITO , Matthew James BOTTOMLEY , Andrea CARFI , Sumana CHANDRAMOULI , Kate LUISI
IPC: C07K14/045 , A61K38/00 , A61K39/245
Abstract: Described are mutant human cytomegalovirus (HCMV) pentamer complex polypeptides, methods of making them, and their use in HCMV protein complexes and compositions. In particular, the use of the modified HCMV polypeptides to stabilize HCMV complexes or unmask a pentamer epitope is described.
-
公开(公告)号：US20230250142A1
公开(公告)日：2023-08-10
申请号：US18008771
申请日：2021-06-11
Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
Inventor： Matthew James BOTTOMLEY , Roberta COZZI , Newton Muchugu WAHOME
CPC classification number: C07K14/47 , A61K47/42 , A61K47/646 , A61K47/61 , C12N15/63 , C07K2319/33
Abstract: Pairs of peptides capable of forming spontaneous covalent bonds, and their uses, such as in forming fusion proteins.
-
公开(公告)号：US20230303637A1
公开(公告)日：2023-09-28
申请号：US18008767
申请日：2021-06-11
Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
Inventor： Matthew James BOTTOMLEY , Newton Muchugu WAHOME
IPC: C07K14/315 , A61K39/09
CPC classification number: C07K14/315 , A61K39/092 , A61K2039/55555 , C07K2319/21
Abstract: Polypeptides capable of self-assembling into a nanoparticle, and nanoparticles made up of such polypeptides.
-
公开(公告)号：US20210277067A1
公开(公告)日：2021-09-09
申请号：US17223207
申请日：2021-04-06
Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
Inventor： Enrico MALITO , Matthew James BOTTOMLEY , Andrea CARFI , Sumana CHANDRAMOULI , Kate LUISI
IPC: C07K14/045 , A61K39/245 , A61K38/00
Abstract: Described are mutant human cytomegalovirus (HCMV) pentamer complex polypeptides, methods of making them, and their use in HCMV protein complexes and compositions. In particular, the use of the modified HCMV polypeptides to stabilize HCMV complexes or unmask a pentamer epitope is described.
-
-
-
Search Results
4
records
(took 0.011 seconds)
