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公开(公告)号：US20230071675A1
公开(公告)日：2023-03-09
申请号：US17663749
申请日：2022-05-17
Inventor： Adam Kenneth CHARNLEY , Michael G DARCY , Jason W. DODSON , Xiaoyang DONG , Terry V. HUGHES , Jianxing KANG , Lara LEISTER , Yiqian LIAN , Yue LI , John F. MEHLMANN , Neysa NEVINS , Joshi M. RAMANJULU , Joseph J. ROMANO , Gren Z. WANG , Guosen YE , Daohua ZHANG
IPC: C07D403/14 , C07D405/14 , C07D413/14 , C07D487/22 , C07D493/10 , C07D498/18 , C07F9/6558
Abstract: Disclosed are compounds having the formula: wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, and R17, are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.
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公开(公告)号：US20180085365A1
公开(公告)日：2018-03-29
申请号：US15811712
申请日：2017-11-14
Inventor： Michael Jonathan BURY , Linda N. CASILLAS , Adam Kenneth CHARNLEY , Pamela A. HAILE , Robert W. MARQUIS, JR. , John F. MEHLMANN , Joseph J. ROMANO , Robert R. SINGHAUS, JR. , Gren Z. WANG
IPC: A61K31/4709 , A61K31/4706
CPC classification number: A61K31/4709 , A61K31/4706 , C07D215/44 , C07D401/12 , C07D405/12 , C07D405/14 , C07D417/12 , C07D417/14 , C07D471/04
Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.
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公开(公告)号：US20210238172A1
公开(公告)日：2021-08-05
申请号：US16652780
申请日：2018-10-04
Inventor： Adam Kenneth CHARNLEY , Michael Gerard DARCY , Jason W. DODSON , Xiaoyang DONG , David FAVRE , Terry Vincent HUGHES , Jianxing KANG , Lara Kathryn LEISTER , Yuehu LI , Yiqian LIAN , John F. MEHLMANN , Neysa NEVINS , Joshi M. RAMANJULU , Joseph J. ROMANO , Gren Z. WANG , Guosen YE , Daohua ZHANG
IPC: C07D413/14
Abstract: The invention relates to combinations comprising a compound of the formula: or a salt thereof; and one or more additional pharmaceutically agents active against HIV, and methods of using the same.
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公开(公告)号：US20170128437A1
公开(公告)日：2017-05-11
申请号：US15413792
申请日：2017-01-24
Inventor： Michael Jonathan BURY , Linda N. CASILLAS , Adam Kenneth CHARNLEY , Pamela A. HAILE , Robert W. MARQUIS, JR. , John F. MEHLMANN , Joseph J. ROMANO , Robert R. SINGHAUS, JR. , Gren Z. WANG
IPC: A61K31/4709 , A61K31/4706
CPC classification number: A61K31/4709 , A61K31/4706 , C07D215/44 , C07D401/12 , C07D405/12 , C07D405/14 , C07D417/12 , C07D417/14 , C07D471/04
Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.
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