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    Extended Use Medical Device
    3.
    发明申请
    Extended Use Medical Device 有权
    延长使用医疗器械

    公开(公告)号：US20110054390A1

    公开(公告)日：2011-03-03

    申请号：US12585061

    申请日：2009-09-02

    申请人： Gary Searle ,  Keith N. Knapp ,  Roman Tunkel ,  Peter Skutnik ,  Lionel Vedrine

    发明人： Gary Searle ,  Keith N. Knapp ,  Roman Tunkel ,  Peter Skutnik ,  Lionel Vedrine

    IPC分类号： A61M5/168 ,  A61M5/142

    CPC分类号： A61M5/158 ,  A61M5/1413 ,  A61M5/14212 ,  A61M5/14224 ,  A61M5/14248 ,  A61M5/16886 ,  A61M5/1723 ,  A61M5/3134 ,  A61M5/385 ,  A61M5/46 ,  A61M2005/14208 ,  A61M2005/14268 ,  A61M2005/1585 ,  A61M2005/16872 ,  A61M2205/16 ,  A61M2205/702 ,  A61M2209/045 ,  A61M2230/005 ,  A61M2230/201

    摘要： Provided is an extended use self-contained, wearable medical device. The device is preferably configured with an infusion deployment mechanism for variably inserting and retracting an infusion needle to different depths, or completely retracting the infusion needle from the infusion site and then re-inserting the infusion needle after a predetermined period of time, throughout an infusion cycle for extending the viability of the infusion site. Another embodiment comprises dual needle deployment mechanisms which may also variably insert and retract the infusion needles. A flow sensor is preferably provided for detecting the stoppage of flow through the infusion cannula and signaling the needle deployment mechanism to attempt infusion at a different depth or to deploy a second infusion needle. A re-fillable reservoir assembly is preferably provided for supplying a drug over the extended use of the device. Another embodiment comprises a partially reusable and partially disposable medical device implementing the above features.

    摘要翻译： 提供了一种扩展使用的独立的，可穿戴的医疗设备。 该装置优选地配置有输注展开机构，用于将输注针可变地插入和缩回到不同的深度，或者将输注针从输注部位完全缩回，然后在整个输注期间在预定时间段之后重新插入输注针 循环，以延长输注部位的生存能力。 另一个实施例包括双针展开机构，其也可以可变地插入和缩回输注针。 优选地设置流量传感器，用于检测通过输注套管的流动的停止并且发出针部署机构以尝试在不同深度输注或部署第二输注针。 优选地，可重新填充的储存器组件用于通过扩展使用该装置来供应药物。 另一实施例包括实现上述特征的部分可再利用和部分一次性医疗装置。

    Extended use medical device
    4.
    发明授权
    Extended use medical device 有权
    延长使用医疗器械

    公开(公告)号：US09375529B2

    公开(公告)日：2016-06-28

    申请号：US12585061

    申请日：2009-09-02

    申请人： Gary Searle ,  Keith N Knapp ,  Roman Tunkel ,  Peter Skutnik ,  Lionel Vedrine

    发明人： Gary Searle ,  Keith N Knapp ,  Roman Tunkel ,  Peter Skutnik ,  Lionel Vedrine

    IPC分类号： A61M5/168 ,  A61M5/142 ,  A61M5/172 ,  A61M5/31 ,  A61M5/14 ,  A61M5/38 ,  A61M5/46 ,  A61M5/158

    CPC分类号： A61M5/158 ,  A61M5/1413 ,  A61M5/14212 ,  A61M5/14224 ,  A61M5/14248 ,  A61M5/16886 ,  A61M5/1723 ,  A61M5/3134 ,  A61M5/385 ,  A61M5/46 ,  A61M2005/14208 ,  A61M2005/14268 ,  A61M2005/1585 ,  A61M2005/16872 ,  A61M2205/16 ,  A61M2205/702 ,  A61M2209/045 ,  A61M2230/005 ,  A61M2230/201

    摘要： Provided is an extended use self-contained, wearable medical device. The device is preferably configured with an infusion deployment mechanism for variably inserting and retracting an infusion needle to different depths, or completely retracting the infusion needle from the infusion site and then re-inserting the infusion needle after a predetermined period of time, throughout an infusion cycle for extending the viability of the infusion site. Another embodiment comprises dual needle deployment mechanisms which may also variably insert and retract the infusion needles. A flow sensor is preferably provided for detecting the stoppage of flow through the infusion cannula and signaling the needle deployment mechanism to attempt infusion at a different depth or to deploy a second infusion needle. A re-fillable reservoir assembly is preferably provided for supplying a drug over the extended use of the device. Another embodiment comprises a partially reusable and partially disposable medical device implementing the above features.

    摘要翻译： 提供了一种扩展使用的独立的，可穿戴的医疗设备。 该装置优选地配置有输注展开机构，用于将输注针可变地插入和缩回到不同的深度，或者将输注针从输注部位完全缩回，然后在整个输注期间在预定时间段之后重新插入输注针 循环，以延长输注部位的生存能力。 另一个实施例包括双针展开机构，其也可以可变地插入和缩回输注针。 优选地提供流量传感器用于检测通过输注套管的流动的停止并且发出针部署机构以尝试在不同深度输注或部署第二输注针。 优选地，可重新填充的储存器组件用于通过扩展使用该装置来供应药物。 另一实施例包括实现上述特征的部分可再利用和部分一次性医疗装置。

    Flexible and Conformal Patch Pump
    5.
    发明申请
    Flexible and Conformal Patch Pump 审中-公开
    柔性和保形补片泵

    公开(公告)号：US20110054285A1

    公开(公告)日：2011-03-03

    申请号：US12585062

    申请日：2009-09-02

    申请人： Gary Searle ,  Keith N. Knapp ,  Peter Skutnik ,  Aidan Petrie ,  Dan Nelsen ,  Paul Brown

    发明人： Gary Searle ,  Keith N. Knapp ,  Peter Skutnik ,  Aidan Petrie ,  Dan Nelsen ,  Paul Brown

    IPC分类号： A61M5/142 ,  A61B5/00 ,  B23P11/00

    CPC分类号： A61M5/14244 ,  A61B5/14532 ,  A61B5/14542 ,  A61M5/16804 ,  A61M5/1723 ,  A61M2005/14252 ,  A61M2005/1583 ,  A61M2205/36 ,  Y10T29/49826

    摘要： Provided is a flexible and conformal wearable, self-contained medical device. The medical device comprises an integral housing formed by a flexible upper portion and a flexible lower portion joined along their perimeters. The medical device is also provided in a plurality of shapes and configurations for increasing the flexibility and conformability of the housing. The components contained within the housing, such as a drug reservoir, printed circuit board, and power supply are preferably constructed from flexible materials and are formed, connected and positioned according to the configuration of the housing in a manner for enhancing flexibility of the housing. A thermal bubble micropump is provided for controlling flow of a drug from the flexible reservoir, that utilizes a thermal resistor provided locally to a thermal expansion fluid that causes a surrounding membrane to expand and displace a volume of drug to be provided to the user.

    摘要翻译： 提供了一种柔性和适形的穿戴式，独立的医疗设备。 医疗装置包括由柔性上部部分和沿其周边连接的柔性下部部分形成的整体壳体。 医疗装置还设置有多个形状和构造，用于增加壳体的柔性和适应性。 包含在壳体内的诸如药物储存器，印刷电路板和电源的部件优选地由柔性材料构成，并且以提高壳体的柔性的方式根据壳体的构造形成，连接和定位。 提供了一种用于控制来自柔性储存器的药物流动的热泡微型泵，其利用局部地提供热膨胀流体的热电阻器，该热电阻器使周围的膜膨胀并移位一定量的待提供给使用者的药物。

    Flexible and conformal patch pump
    6.
    发明授权
    Flexible and conformal patch pump 有权

    公开(公告)号：US10092691B2

    公开(公告)日：2018-10-09

    申请号：US12585062

    申请日：2009-09-02

    申请人： Gary Searle ,  Keith N Knapp ,  Peter Skutnik ,  Aidan Petrie ,  Dan Nelsen ,  Paul Brown

    发明人： Gary Searle ,  Keith N Knapp ,  Peter Skutnik ,  Aidan Petrie ,  Dan Nelsen ,  Paul Brown

    IPC分类号： A61M37/00 ,  A61M5/142 ,  A61M5/168 ,  A61B5/145 ,  A61M5/172 ,  A61M5/158

    摘要： Provided is a flexible and conformal wearable, self-contained medical device. The medical device comprises an integral housing formed by a flexible upper portion and a flexible lower portion joined along their perimeters. The medical device is also provided in a plurality of shapes and configurations for increasing the flexibility and conformability of the housing. The components contained within the housing, such as a drug reservoir, printed circuit board, and power supply are preferably constructed from flexible materials and are formed, connected and positioned according to the configuration of the housing in a manner for enhancing flexibility of the housing. A thermal bubble micropump is provided for controlling flow of a drug from the flexible reservoir, that utilizes a thermal resistor provided locally to a thermal expansion fluid that causes a surrounding membrane to expand and displace a volume of drug to be provided to the user.

    LOW DOSE PREFILLED DRUG DELIVERY DEVICE AND METHOD
    7.
    发明申请
    LOW DOSE PREFILLED DRUG DELIVERY DEVICE AND METHOD 有权
    低剂量预制药物递送装置和方法

    公开(公告)号：US20130006216A1

    公开(公告)日：2013-01-03

    申请号：US13261383

    申请日：2011-01-31

    申请人： Margaret Taylor ,  James Bates ,  Roman Tunkel ,  Jay Butterbrodt ,  Gary Searle ,  Joshua Horvath ,  Keith Knapp, II ,  Edward Gillen

    发明人： Margaret Taylor ,  James Bates ,  Roman Tunkel ,  Jay Butterbrodt ,  Gary Searle ,  Joshua Horvath ,  Keith Knapp, II ,  Edward Gillen

    IPC分类号： A61M5/315 ,  A61M5/20 ,  A61M5/32

    CPC分类号： A61M5/2425 ,  A61M5/2459 ,  A61M5/3287 ,  A61M5/425 ,  A61M2005/005 ,  A61M2005/206

    摘要： A drug delivery device (100) for administering a low dose of a medicament includes a housing (111) and a drug reservoir (101) disposed in the housing (111). A needle (135) is connected to the drug reservoir (101). A pressure applying member (113) is movably connected to the housing (111) and is movable between first and second positions. The pressure applying member (113) does not apply pressure to the drug reservoir (101) in the first position and applies pressure to the drug reservoir (101) in the second position to dispense medicament stored in the drug reservoir (101). A method of administering a low dose of insulin to simulate a first-phase insulin response of a pancreas is also disclosed.

    摘要翻译： 用于施用低剂量药物的药物递送装置（100）包括设置在壳体（111）中的壳体（111）和药物储存器（101）。 针（135）连接到药物储存器（101）。 压力施加构件（113）可移动地连接到壳体（111）并且可在第一和第二位置之间移动。 压力施加构件（113）在第一位置不对药物储存器（101）施加压力，并且在第二位置向药物储存器（101）施加压力以分配存储在药物储存器（101）中的药物。 还公开了施用低剂量胰岛素以模拟胰腺的第一阶段胰岛素反应的方法。

    Heat exchanger connector assembly
    9.
    发明申请
    Heat exchanger connector assembly 有权
    热交换器连接器组件

    公开(公告)号：US20100241073A1

    公开(公告)日：2010-09-23

    申请号：US12382454

    申请日：2009-03-17

    申请人： Eric Andersen ,  David Baker ,  Gregory Hughes ,  Liam O'Shea ,  Gary Searle

    发明人： Eric Andersen ,  David Baker ,  Gregory Hughes ,  Liam O'Shea ,  Gary Searle

    IPC分类号： A61F7/12 ,  F28F9/02

    CPC分类号： F28F9/0246 ,  A61M5/44 ,  A61M39/10 ,  A61M39/105 ,  A61M2039/1072 ,  Y10S604/905

    摘要： A connector assembly for a heat exchanger has a fitting and a mount to which the fitting couples. The fitting has an elongate body having a proximal portion and a distal portion. At the proximal portion there is a crossbar, and at the distal portion there are an inlet and an outlet that protrude away from the body. Two wings extend from the body in a direction opposite to that of the inlet and outlet. There is formed on each of the wings a locking protrusion. The mount has a top portion where there is a groove dimensioned to accept the crossbar of the fitting. A longitudinal channel is formed orthogonal to the groove in the mount. Two sidewalls extend from the mount each for accepting a corresponding one of the wings, when the fitting is coupled to the mount. Apertures are provided at the sidewalls to engage the protrusion at the wings so that, once the fitting is coupled to the mount, it is secured thereto, until a force is exerted to compress the wings towards each other to disengage the protrusions from the apertures. To couple the fitting to the mount, a user first positions the crossbar of the fitting onto the groove of the mount, with the body of the fitting at an angle relative to the mount. With the crossbar resting on the groove, a pivot point is established between the fitting and the mount, so that the body of the fitting can be pivotally positioned within the channel of the mount. At that time the inlet and outlet of the fitting are mated to an output port and an input port, respectively, of the mount; and the protrusions at the wings of the fitting are engaged to the apertures at the sidewalls of the mount. An infusate line and a heat exchanger are connected to the proximal end and distal end, respectively, of the fitting.

    摘要翻译： 用于热交换器的连接器组件具有配件和配件相配合的安装件。 配件具有细长体，其具有近端部分和远端部分。 在近端部分处有横杆，并且在远侧部分处具有远离身体突出的入口和出口。 两个翼沿着与入口和出口相反的方向从身体延伸。 在每个翼上形成有锁定突起。 安装座具有顶部，其中有一个凹槽的尺寸以接受配件的横杆。 纵向通道形成为与安装件中的凹槽正交。 当配件联接到安装座时，两个侧壁从每个安装件延伸以接收相应的一个翼。 孔设置在侧壁处以与翼部处的突起接合，使得一旦接头联接到安装件上，其被固定到其上，直到施加力以将翼片朝向彼此压缩以使突起与孔分离。 为了将配件联接到安装座，用户首先将配件的横杆定位在安装件的凹槽上，使配件的主体相对于安装座成一角度。 在横杆搁置在槽上，在配件和安装座之间建立枢轴点，使得配件的主体可以枢转地定位在安装件的通道内。 此时，配件的入口和出口分别与安装座的输出端口和输入端口配合; 并且配件的翼部处的突起接合到安装件的侧壁处的孔。 输液管线和热交换器分别连接到配件的近端和远端。

    MULTI-FLUID DELIVERY SYSTEM
    10.
    发明申请
    MULTI-FLUID DELIVERY SYSTEM 审中-公开
    多流体输送系统

    公开(公告)号：US20100094089A1

    公开(公告)日：2010-04-15

    申请号：US12571006

    申请日：2009-09-30

    申请人： Eric Litscher ,  Gerald Heller ,  Danny Macari ,  Charles McCall ,  Eric Rioux ,  Gary Searle ,  Arthur Stephen

    发明人： Eric Litscher ,  Gerald Heller ,  Danny Macari ,  Charles McCall ,  Eric Rioux ,  Gary Searle ,  Arthur Stephen

    IPC分类号： A61B1/00

    CPC分类号： A61B1/015 ,  A61B1/00103

    摘要： A proximal connector of an endoscope shaft can be manually attached to and detached from a console, such that the connector and endoscope shaft can be provided as a single use device. An interface between the proximal connector and console can include a sliding plate moveable to operably make and break at least some of the connections between the console and endoscope shaft. A fluid reservoir may be separately connected to the proximal connector and hang from a mount on the interface.

    摘要翻译： 内窥镜轴的近侧连接器可以手动地附接到控制台并从控制台拆卸，使得连接器和内窥镜轴可以被提供为单次使用装置。 近端连接器和控制台之间的接口可以包括滑动板，其可移动以可操作地制造和断开控制台和内窥镜轴之间的至少一些连接。 流体储存器可以单独地连接到近端连接器并且从接口上的支架悬挂。