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公开(公告)号：US10377823B2
公开(公告)日：2019-08-13
申请号：US15231032
申请日：2016-08-08
Applicant: Genentech, Inc.
Inventor： Hilary Clark , Dan Eaton , Lino Gonzalez, Jr. , Jane Grogan , Jason A. Hackney , Kristin Bowles , Xin Yu
IPC: C07K16/00 , C12P21/08 , C07K16/28 , C07K14/705 , C07K16/18 , G01N33/50 , G01N33/564 , G01N33/569 , C07K14/47 , A61K39/00
Abstract: The present invention relates to compositions and methods of using those compositions for the diagnosis and treatment of immune related diseases.
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公开(公告)号：USRE46534E1
公开(公告)日：2017-09-05
申请号：US14699845
申请日：2015-04-29
Applicant: Genentech, Inc.
Inventor： Daryl T. Baldwin , Sarah C. Bodary-Winter , Andrew C. Chan , Hilary Clark , Janet K. Jackman , William I. Wood
CPC classification number: C07K16/18 , A61K2039/505 , C07K14/47 , C12N2799/026 , C12Q1/6883 , C12Q2600/158 , G01N2500/10 , G01N2800/065 , G01N2800/205 , G01N2800/24
Abstract: The present invention relates to compositions containing a novel protein and methods of using those compositions for the diagnosis and treatment of immune related diseases involving detection of the PRO52254 polypeptide.
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公开(公告)号：USRE46816E1
公开(公告)日：2018-05-01
申请号：US14228173
申请日：2014-03-27
Applicant: Genentech, Inc.
Inventor： Daryl T. Baldwin , Sarah C. Bodary-Winter , Andrew C. Chan , Hilary Clark , Janet K. Jackman , William I. Wood
CPC classification number: C07K16/18 , A61K2039/505 , C07K14/47 , C12N2799/026 , C12Q1/6883 , C12Q2600/158 , G01N2500/10 , G01N2800/065 , G01N2800/205 , G01N2800/24
Abstract: The present invention relates to compositions containing a novel protein and methods of using those compositions for the diagnosis and treatment of immune related diseases involving detection of the PRO52254 polypeptide.
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公开(公告)号：US20150166631A1
公开(公告)日：2015-06-18
申请号：US14451764
申请日：2014-08-05
Applicant: GENENTECH, INC.
Inventor： Hilary Clark , Daniel L. Eaton , Bernd Wranik , Wenjun Ouyang , Lino Gonzalez , Austin L. Gurney
IPC: C07K14/705 , C07K16/28 , G01N33/574 , G01N33/68
CPC classification number: C07K14/705 , A61K38/00 , C07K16/28 , C07K2319/00 , G01N33/5011 , G01N33/57407 , G01N33/6893 , G01N2333/705 , G01N2800/065 , G01N2800/24 , G01N2800/245
Abstract: The present invention relates to compositions containing a novel protein and methods of using those compositions for the diagnosis and treatment of immune related disease.
Abstract translation: 本发明涉及含有新蛋白质的组合物和使用这些组合物来诊断和治疗免疫相关疾病的方法。
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5.发明申请公开(公告)号：US20140371086A1
公开(公告)日：2014-12-18
申请号：US14290453
申请日：2014-05-29
Applicant: GENENTECH, INC.
Inventor： Alexander Abbas , Hilary Clark , Wenjun Ouyang , P. Mickey Williams , William I. Wood , Thomas D. Wu
CPC classification number: C12Q1/6837 , C07K14/47 , C12N9/2417 , C12Y302/01001 , G01N33/53 , G01N33/564 , G01N33/6893 , G01N2800/24
Abstract: The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
Abstract translation: 本发明涉及含有新蛋白质的组合物和使用这些组合物来诊断和治疗免疫相关疾病的方法。
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Patent Agency Ranking
公开(公告)号：US20140179620A1
公开(公告)日：2014-06-26
申请号：US13964861
申请日：2013-08-12
Applicant: GENENTECH, INC.
Inventor： Alexander R. Abbas , Hilary Clark , Lauri Diehl , Charles Lees , Colin L. Noble , Jack Satsangi
IPC: C12Q1/68 , G01N33/564
CPC classification number: G01N33/564 , A61K31/56 , A61K31/606 , C12Q1/6883 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172
Abstract: The present invention relates to methods of gene expression profiling for inflammatory bowel disease pathogenesis, in which the differential expression in a test sample from a mammalian subject of one or more IBD markers relative to a control is determined, wherein the differential expression in the test sample is indicative of an IBD in the mammalian subject from which the test sample was obtained.
Abstract translation: 本发明涉及炎症性肠病发病机理的基因表达谱的方法，其中测定来自一个或多个IBD标记物的哺乳动物受试者相对于对照的测试样品中的差异表达，其中测试样品中的差异表达 指示获得测试样品的哺乳动物受试者中的IBD。
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公开(公告)号：US20140154275A1
公开(公告)日：2014-06-05
申请号：US14020628
申请日：2013-09-06
Applicant: GENENTECH, INC.
Inventor： Alexander R. Abbas , Hilary Clark , Lauri Diehl , Charles Lees , Colin L. Noble , Jack Satsangi
IPC: C12Q1/68
CPC classification number: C12Q1/6883 , C12Q2600/158
Abstract: The present invention relates to methods of gene expression profiling for inflammatory bowel disease pathogenesis, in which the differential expression in a test sample from a mammalian subject of one or more IBD markers relative to a control is determined, wherein the differential expression in the test sample is indicative of an IBD in the mammalian subject from which the test sample was obtained.
Abstract translation: 本发明涉及炎症性肠病发病机理的基因表达谱的方法，其中测定来自一个或多个IBD标记物的哺乳动物受试者相对于对照的测试样品中的差异表达，其中测试样品中的差异表达 指示获得测试样品的哺乳动物受试者中的IBD。
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8.发明申请METHOD OF TREATING AUTOIMMUNE INFLAMMATORY DISORDERS USING IL-23R LOSS-OF-FUNCTION MUTANTS 审中-公开使用IL-23R功能失调症治疗自身免疫性炎症性疾病的方法公开(公告)号：US20140037618A1
公开(公告)日：2014-02-06
申请号：US13902714
申请日：2013-05-24
Applicant: GENENTECH, INC.
Inventor： Svetlana Pidasheva , Hilary Clark , Nico P. Ghilardi , Timothy W. Behrens , Hergen Spits , Sara Trifari
CPC classification number: G01N33/6872 , C12Q1/6883 , C12Q2600/106 , C12Q2600/156
Abstract: The present invention relates to compositions and methods of diagnosing and treating autoimmune and inflammatory disorders that are characterized by IL-23R loss-of-function mutations.
Abstract translation: 本发明涉及以IL-23R功能丧失突变为特征的诊断和治疗自身免疫性和炎症性疾病的组合物和方法。
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公开(公告)号：USRE46805E1
公开(公告)日：2018-04-24
申请号：US14228172
申请日：2014-03-27
Applicant: Genentech, Inc.
Inventor： Daryl T. Baldwin , Sarah C. Bodary-Winter , Andrew C. Chan , Hilary Clark , Janet K. Jackman , William I. Wood
CPC classification number: C07K16/18 , A61K2039/505 , C07K14/47 , C12N2799/026 , C12Q1/6883 , C12Q2600/158 , G01N2500/10 , G01N2800/065 , G01N2800/205 , G01N2800/24
Abstract: The present invention relates to compositions containing a novel protein and methods of using those compositions for the diagnosis and treatment of immune related diseases involving detection of the PRO52254 polypeptide.
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公开(公告)号：US09499596B2
公开(公告)日：2016-11-22
申请号：US13648191
申请日：2012-10-09
Applicant: Genentech, Inc.
Inventor： Hilary Clark , Dan Eaton , Lino Gonzalez , Jane Grogan , Jason Hackney , Kristin Bowles , Xin Yu
IPC: A61K39/35 , C12N5/00 , C12N5/02 , C07K16/00 , C07K14/47 , C07K14/705 , C07K16/18 , C07K16/28 , G01N33/50 , G01N33/564 , G01N33/569 , A61K39/00
CPC classification number: C07K16/2803 , A61K2039/505 , C07K14/4702 , C07K14/70503 , C07K16/18 , C07K2317/33 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/75 , C07K2317/76 , G01N33/505 , G01N33/564 , G01N33/56972 , Y02A50/466
Abstract: The present invention relates to compositions and methods of using those compositions for the diagnosis and treatment of immune related diseases.
Abstract translation: 本发明涉及使用这些组合物来诊断和治疗免疫相关疾病的组合物和方法。
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