摘要:
The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels.
摘要:
The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels.
摘要:
The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels.
摘要:
The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels.
摘要:
The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels.
摘要:
The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels.
摘要:
Disclosed is a method for estimating a density of an earth formation penetrated by a borehole. The method includes: emitting a pulse of fast neutrons into the formation during a neutron-pulse time interval; detecting gamma-rays due to inelastic scattering and thermal capture of the emitted neutrons in the formation to provide a gamma-ray energy spectrum due to the inelastic scattering and the thermal capture during a first time interval within the neutron-pulse time interval and to provide a time spectrum of counts or count rates due to thermal capture during a second time interval occurring after the neutron-pulse time interval; determining a macroscopic capture cross section of the formation from a decay in the time spectrum of counts or count rates; determining an elemental weight fraction from the gamma-ray energy spectrum; and estimating the density of the formation using the macroscopic capture cross section and the elemental weight fraction.
摘要:
An apparatus for estimating properties of an earth formation includes a carrier configured to be disposed in a borehole in the earth formation, and a sample retriever configured to remove a sample of the earth formation, the sample including solid components of the earth formation. The apparatus also includes an analysis assembly including a chamber disposed with the carrier and configured to hold the sample, an X-ray source configured to irradiate the sample with X-ray radiation while the sample is disposed in the chamber, and one or more X-ray detectors configured to detect radiation emitted from the sample in response to irradiation from the X-ray source.
摘要:
An auto grid moving apparatus for an X ray imaging device is provided. The apparatus includes: a grid; a grid holder on which the grid is disposed; a fixing base; and a double sided timing belt geared with at least two timing wheels at the two ends of the timing belt on the inner side face of the timing belt and geared with the grid holder at the outer side face of the timing belt, wherein one of the timing wheels has a motor disposed thereon, the motor being configured to drive the timing wheel to move the timing belt and to drive the grid holder to move.
摘要:
A liver cancer metastasis therapeutic device, consisting of a base plate, a prone support, an abdominal medicine massager, a chain wheel, a rotating wheel and a handheld massager, and being used in a treatment for restoring functions of a whole body; and the therapeutic device is focused on restoring the functions of the whole human body and complementarily performs chemoradiotherapy and surgery for killing cancer cells to treat causes of death, thus significantly reducing a death rate of patients due to metastasis of liver cancers and digestive organ cancers.