公开(公告)号：US20100268294A1

公开(公告)日：2010-10-21

申请号：US12749723

申请日：2010-03-30

申请人： Michael Vollkron ,  Gerald Czygan ,  Thomas Kraemer ,  Michael Lippert ,  Olaf Skerl

发明人： Michael Vollkron ,  Gerald Czygan ,  Thomas Kraemer ,  Michael Lippert ,  Olaf Skerl

IPC分类号： A61N1/365 ,  G06N5/02 ,  G06F11/07 ,  G06F17/00 ,  A61B5/021 ,  A61B5/0452 ,  A61N1/39

CPC分类号： A61N1/3627 ,  A61B5/0215 ,  A61B5/02158 ,  A61B5/053 ,  A61B5/1076 ,  A61N1/365 ,  A61N1/36521 ,  A61N1/36528 ,  A61N1/36564 ,  A61N1/36578

摘要： Embodiments relate to a heart monitor, which is connected to or can be connected to at least one sensor for pressure and volume data or equivalent substitute variables and which comprises an evaluation unit for processing at least one input signal reflecting the temporal course of pressure and volume data or equivalent substitute variables of the heart. The evaluation unit is configured such that it segments the input signal in accordance with individual completed cardiac cycles and examines segments of the input signal obtained in this way as to whether a particular segment of the input signal represents a PV diagram, which corresponds to specified quality conditions regarding the direction of circulation, morphology and distance between a starting and end values.

摘要翻译： 实施例涉及心脏监测器，心脏监测器连接到或可以连接至至少一个用于压力和体积数据或等效替代变量的传感器，并且其包括用于处理反映压力和体积的时间过程的至少一个输入信号的评估单元 数据或等效替代变量的心脏。 评估单元被配置为使得其根据各个完成的心动周期来分段输入信号，并且检查以这种方式获得的输入信号的段是关于输入信号的特定段是否表示对应于指定质量的PV图 关于循环方向，形态以及起始和终点之间的距离的条件。

公开(公告)号：US20100010354A1

公开(公告)日：2010-01-14

申请号：US12497778

申请日：2009-07-06

申请人： Olaf Skerl ,  Michael Lippert ,  Gerald Czygan

发明人： Olaf Skerl ,  Michael Lippert ,  Gerald Czygan

IPC分类号： A61B8/14

CPC分类号： A61B5/1107 ,  A61B5/0031 ,  A61B5/029 ,  A61B5/107 ,  A61B5/6846 ,  A61B5/686 ,  A61B8/02 ,  A61B8/06 ,  A61B8/0833 ,  A61B8/12 ,  A61B8/42 ,  A61B8/4483 ,  A61B8/543 ,  A61N1/36578

摘要： An implantable measurement arrangement for intracorporeal acoustic measurement of geometric parameters and motion parameters in and on organs and/or tissues of a patient includes an implantable device, in particular an electromedical device; an implantable sonic transducer for transmitting and receiving ultrasonic waves, the transducer being in signal connection with the implantable device; and an implantable reflector in communication with the implantable device and situated at a distance from the sonic transducer for reflecting the ultrasonic waves back in the direction of the sonic transducer. The electromedical device can analyze the ultrasonic waves picked up and reflected back by the sonic transducer.

摘要翻译： 用于体内和/或组织中几何参数和运动参数的体内声学测量的可植入测量装置包括可植入装置，特别是电动医疗装置; 用于发射和接收超声波的可植入声波换能器，所述换能器与所述可植入装置信号连接; 以及可植入反射器，其与所述可植入装置连通并且位于距离所述声音换能器一定距离处，用于将所述超声波反射回所述声音换能器的方向。 电子设备可以分析由声音传感器拾取并反射回的超声波。

公开(公告)号：US08965493B2

公开(公告)日：2015-02-24

申请号：US13040926

申请日：2011-03-04

申请人： Olaf Skerl ,  Michael Lippert ,  Gerald Czygan

发明人： Olaf Skerl ,  Michael Lippert ,  Gerald Czygan

IPC分类号： A61B5/04 ,  A61B5/053 ,  A61B5/00

CPC分类号： A61B5/0535 ,  A61B5/6846 ,  A61B5/7207 ,  A61B2562/0209 ,  A61B2562/043

摘要： An electromedical implant for monitoring a thoracic property of a living being is provided that includes a detector arrangement including an impedance measuring unit and an electrode arrangement, which are equipped to capture a measurement signal associated with the thoracic property in the form of an impedance signal; a monitoring arrangement, which is connected to the detector arrangement and equipped to generate a parameter from the measurement signal that is indicative of the thoracic property, and an evaluation unit, which is connected to the monitoring arrangement and equipped to determine an evaluation result regarding the thoracic property based on the parameter. According to the invention, the electrode arrangement comprises at least a plurality of mutually isolated electrodes, which are disposed on the housing and operatively connected by way of the impedance measuring unit and which can be separately controlled, wherein an electrode body has a strip shape.

摘要翻译： 提供了一种用于监测生命体的胸部性质的电植入物，其包括检测器装置，所述检测器装置包括阻抗测量单元和电极装置，其被配备为以阻抗信号的形式捕获与胸部特性相关联的测量信号; 监视装置，其连接到所述检测器装置，并且被配备为从所述测量信号生成指示胸部特性的参数;以及评估单元，所述评估单元连接到所述监视装置并被配备以确定关于所述检测装置的评估结果 胸部属性基于参数。 根据本发明，电极布置包括至少多个相互隔离的电极，它们设置在壳体上并且通过阻抗测量单元可操作地连接并且可以被单独控制，其中电极体具有带状。

公开(公告)号：US08491485B2

公开(公告)日：2013-07-23

申请号：US13038428

申请日：2011-03-02

申请人： Gerald Czygan ,  Michael Lippert ,  Olaf Skerl

发明人： Gerald Czygan ,  Michael Lippert ,  Olaf Skerl

IPC分类号： A61B5/024 ,  A61B5/026

CPC分类号： A61B5/0535 ,  A61B5/029 ,  A61B5/0295 ,  A61B5/0402 ,  A61B5/6846 ,  A61B5/721 ,  A61B5/7214 ,  A61B5/7275

摘要： An electromedical implant (100, 101, 102, 103) for monitoring a cardiac blood flow (B1) of a patient includes a detector (10, 10′, 10″) which obtains a first measurement signal (S1) associated with the cardiac blood flow (B1) and a second measurement signal (S2) associated with the epithoracic, peripheral blood flow (B2). A monitoring assembly (20) then generates a first parameter (P1) from the first measurement signal (S1) which is indicative of a time (tsys) at which blood is ejected from the heart, and a second parameter (2) from the second measurement signal (S2) which is indicative of a time (tgef) of a blood pulse in the thoracic tissue which is associated with the ejection of blood. An evaluation unit (30) then generates a pulse transit time (Δt=tgef−tsys) from the first parameter (P1) and the second parameter (P2). The detector (10, 10′, 10″) includes an impedance measuring unit (12) having an electrode assembly (11, 11′) for detection of at least the second measurement signal (S2) in the form of an impedance signal.

摘要翻译： 用于监测患者的心脏血流（B1）的电植入物（100,101,102,103）包括检测器（10,10'，10“），其获得与心脏相关联的第一测量信号（S1） 血液流（B1）和与脑外周血流（B2）相关联的第二测量信号（S2）。 监测组件（20）然后从第一测量信号（S1）产生指示从心脏喷出血液的时间（tsys）的第一参数（P1），以及来自第二测量信号的第二参数（2） 测量信号（S2），其指示与血液喷射相关联的胸部组织中的血液脉冲的时间（tgef）。 评估单元（30）然后从第一参数（P1）和第二参数（P2）产生脉冲传播时间（Deltat = tgef-tsys）。 检测器（10,10'，10“）包括具有用于以阻抗信号的形式检测至少第二测量信号（S2）的电极组件（11,11'）的阻抗测量单元（12）。

公开(公告)号：US08792970B2

公开(公告)日：2014-07-29

申请号：US12389719

申请日：2009-02-20

申请人： Olaf Skerl ,  Michael Lippert ,  Gerald Czygan ,  Stefan Paule

发明人： Olaf Skerl ,  Michael Lippert ,  Gerald Czygan ,  Stefan Paule

IPC分类号： A61B5/04 ,  A61B5/08 ,  A61N1/365 ,  A61B5/053 ,  A61N1/372

CPC分类号： A61B5/0809 ,  A61B5/0535 ,  A61N1/36521 ,  A61N1/37258

摘要： A system which generates a warning signal in the event of looming pulmonary edema and/or looming decompensation. The system has an impedance detection unit for determining impedance values, which represent a transthoracic impedance course, and an impedance analysis unit (78), which is connected to the impedance detection unit. The impedance analysis unit (78) is implemented to determine the degree of modulation for a particular impedance course detected by the impedance detection unit.

摘要翻译： 在发生肺水肿和/或逼近失代偿的情况下产生警告信号的系统。 系统具有阻抗检测单元，用于确定表示经胸阻抗路线的阻抗值，以及阻抗分析单元（78），其连接到阻抗检测单元。 阻抗分析单元（78）被实现以确定由阻抗检测单元检测到的特定阻抗进程的调制度。

公开(公告)号：US08521265B2

公开(公告)日：2013-08-27

申请号：US12749723

申请日：2010-03-30

申请人： Michael Vollkron ,  Gerald Czygan ,  Thomas Kraemer ,  Michael Lippert ,  Olaf Skerl

发明人： Michael Vollkron ,  Gerald Czygan ,  Thomas Kraemer ,  Michael Lippert ,  Olaf Skerl

IPC分类号： A61B5/04

CPC分类号： A61N1/3627 ,  A61B5/0215 ,  A61B5/02158 ,  A61B5/053 ,  A61B5/1076 ,  A61N1/365 ,  A61N1/36521 ,  A61N1/36528 ,  A61N1/36564 ,  A61N1/36578

摘要： Embodiments relate to a heart monitor, which is connected to or can be connected to at least one sensor for pressure and volume data or equivalent substitute variables and which comprises an evaluation unit for processing at least one input signal reflecting the temporal course of pressure and volume data or equivalent substitute variables of the heart. The evaluation unit is configured such that it segments the input signal in accordance with individual completed cardiac cycles and examines segments of the input signal obtained in this way as to whether a particular segment of the input signal represents a PV diagram, which corresponds to specified quality conditions regarding the direction of circulation, morphology and distance between a starting and end values.

摘要翻译： 实施例涉及心脏监测器，心脏监测器连接到或可以连接至至少一个用于压力和体积数据或等效替代变量的传感器，并且其包括用于处理反映压力和体积的时间过程的至少一个输入信号的评估单元 数据或等效替代变量的心脏。 评估单元被配置为使得其根据各个完成的心动周期来分段输入信号，并且检查以这种方式获得的输入信号的段是关于输入信号的特定段是否表示对应于指定质量的PV图 关于循环方向，形态以及起始和终点之间的距离的条件。

公开(公告)号：US08271085B2

公开(公告)日：2012-09-18

申请号：US11970662

申请日：2008-01-08

申请人： Michael Lippert ,  Olaf Skerl ,  Stefan Paule ,  Bernhard Fahn ,  Gerald Czygan ,  Heinrich Reinke ,  Albrecht Urbaszek

发明人： Michael Lippert ,  Olaf Skerl ,  Stefan Paule ,  Bernhard Fahn ,  Gerald Czygan ,  Heinrich Reinke ,  Albrecht Urbaszek

IPC分类号： A61N1/365

CPC分类号： A61B5/053 ,  A61B5/0538 ,  A61B5/14535 ,  A61B5/7207

摘要： An implantable medical device has an impedance or admittance determination unit, an alternating current or voltage source, a measuring unit, and an analysis unit which is connected to the alternating current or AC voltage source and the measuring unit to calculate an impedance value or an admittance value at different times. The impedance or admittance determination unit may generate measuring current having two different frequencies (preferably below 100 kHz), and the analysis unit may calculate pairs of impedance or admittance values which are chronologically assigned to one another for different frequencies of the measuring current, and calculate a value for a blood impedance or blood admittance component which is independent of the impedance of the body tissue surrounding a particular blood vessel, The analysis unit may also determine trends in this value over time as an indicator for a change of blood hematocrit value.

摘要翻译： 可植入医疗装置具有阻抗或导纳确定单元，交流或电压源，测量单元和分析单元，其连接到交流电压源或交流电压源和测量单元以计算阻抗值或导纳 价值在不同的时间。 阻抗或导纳确定单元可以产生具有两个不同频率（优选低于100kHz）的测量电流，并且分析单元可以计算针对测量电流的不同频率按时间顺序分配给彼此的阻抗或导纳值对，并且计算 血液阻抗或血液导入分量的值，其独立于围绕特定血管的身体组织的阻抗。分析单元还可以确定该值随时间的趋势作为血液血细胞比容值变化的指标。

公开(公告)号：US20110224520A1

公开(公告)日：2011-09-15

申请号：US13040926

申请日：2011-03-04

申请人： Olaf Skerl ,  Michael Lippert ,  Gerald Czygan

发明人： Olaf Skerl ,  Michael Lippert ,  Gerald Czygan

IPC分类号： A61B5/053 ,  A61B5/145

CPC分类号： A61B5/0535 ,  A61B5/6846 ,  A61B5/7207 ,  A61B2562/0209 ,  A61B2562/043

摘要： An electromedical implant for monitoring a thoracic property of a living being is provided that includes a detector arrangement including an impedance measuring unit and an electrode arrangement, which are equipped to capture a measurement signal associated with the thoracic property in the form of an impedance signal; a monitoring arrangement, which is connected to the detector arrangement and equipped to generate a parameter from the measurement signal that is indicative of the thoracic property, and an evaluation unit, which is connected to the monitoring arrangement and equipped to determine an evaluation result regarding the thoracic property based on the parameter. According to the invention, the electrode arrangement comprises at least a plurality of mutually isolated electrodes, which are disposed on the housing and operatively connected by way of the impedance measuring unit and which can be separately controlled, wherein an electrode body has a strip shape.

摘要翻译： 提供了一种用于监测生物体的胸部特性的电植入物，其包括检测器装置，所述检测器装置包括阻抗测量单元和电极装置，其被配备为以阻抗信号的形式捕获与胸部特性相关联的测量信号; 监视装置，其连接到所述检测器装置，并且被配备为从所述测量信号生成指示胸部特性的参数;以及评估单元，所述评估单元连接到所述监视装置并被配备以确定关于所述检测装置的评估结果 胸部属性基于参数。 根据本发明，电极布置包括至少多个相互隔离的电极，它们设置在壳体上并且通过阻抗测量单元可操作地连接并且可以被单独控制，其中电极体具有带状。

公开(公告)号：US08571641B2

公开(公告)日：2013-10-29

申请号：US12757307

申请日：2010-04-09

申请人： Thomas Kraemer ,  Michael Lippert ,  Olaf Skerl ,  Gerald Czygan ,  Stefan Paule

发明人： Thomas Kraemer ,  Michael Lippert ,  Olaf Skerl ,  Gerald Czygan ,  Stefan Paule

IPC分类号： A61B5/04

CPC分类号： A61B5/0537 ,  A61B5/0031 ,  A61B5/1116 ,  A61B5/4869 ,  A61B5/4878 ,  A61B5/6846 ,  A61B5/686 ,  A61B2562/0219 ,  A61N1/36521 ,  A61N1/36542 ,  A61N1/3655 ,  A61N1/36564 ,  A61N1/36571

摘要： A monitoring apparatus having a signal input for signals representing measurement values of one or more physiological parameters, and an evaluation and processing unit connected to the signal input. The evaluation and processing unit is designed to select, or differently weight, individual values from the values received for further processing based on one or more criteria such that measurement values raising doubts as to the validity thereof are not selected or given a very low weighting.

摘要翻译： 一种具有用于表示一个或多个生理参数的测量值的信号的信号输入的监视装置，以及连接到所述信号输入的评估和处理单元。 评估和处理单元被设计为基于一个或多个标准从接收到的值中选择或不同地权重的值，以使得对其有效性产生怀疑的测量值不被选择或给出非常低的加权。

公开(公告)号：US20110224527A1

公开(公告)日：2011-09-15

申请号：US13038428

申请日：2011-03-02

申请人： Gerald Czygan ,  Michael Lippert ,  Olaf Skerl

发明人： Gerald Czygan ,  Michael Lippert ,  Olaf Skerl

IPC分类号： A61B5/0245

CPC分类号： A61B5/0535 ,  A61B5/029 ,  A61B5/0295 ,  A61B5/0402 ,  A61B5/6846 ,  A61B5/721 ,  A61B5/7214 ,  A61B5/7275

摘要： An electromedical implant (100, 101, 102, 103) for monitoring a cardiac blood flow (B1) of a patient includes a detector (10, 10′, 10″) which obtains a first measurement signal (S1) associated with the cardiac blood flow (B1) and a second measurement signal (S2) associated with the epithoracic, peripheral blood flow (B2). A monitoring assembly (20) then generates a first parameter (P1) from the first measurement signal (S1) which is indicative of a time (tsys) at which blood is ejected from the heart, and a second parameter (2) from the second measurement signal (S2) which is indicative of a time (tgef) of a blood pulse in the thoracic tissue which is associated with the ejection of blood. An evaluation unit (30) then generates a pulse transit time (Δt=tgef−tsys) from the first parameter (P1) and the second parameter (P2). The detector (10, 10′, 10″) includes an impedance measuring unit (12) having an electrode assembly (11, 11′) for detection of at least the second measurement signal (S2) in the form of an impedance signal.

摘要翻译： 用于监测患者的心脏血流（B1）的电植入物（100,101,102,103）包括检测器（10,10'，10“），其获得与心脏血液相关联的第一测量信号（S1） 流量（B1）和与外部血液流（B2）相关联的第二测量信号（S2）。 监测组件（20）然后从第一测量信号（S1）产生指示从心脏喷出血液的时间（tsys）的第一参数（P1），以及来自第二测量信号的第二参数（2） 测量信号（S2），其指示与血液喷射相关联的胸部组织中的血液脉冲的时间（tgef）。 然后，评估单元（30）从第一参数（P1）和第二参数（P2）生成脉冲传播时间（＆Dgr; t = tgef-tsys）。 检测器（10,10'，10“）包括阻抗测量单元（12），其具有用于以阻抗信号的形式检测至少第二测量信号（S2）的电极组件（11,11'）。