公开(公告)号：US5683708A

公开(公告)日：1997-11-04

申请号：US536785

申请日：1995-09-29

申请人： Gerhard Gries ,  Gary Grant ,  Grigori Khaskin ,  Regine Gries ,  Keith N. Slessor ,  Jan Liska ,  Petr Kapitola

发明人： Gerhard Gries ,  Gary Grant ,  Grigori Khaskin ,  Regine Gries ,  Keith N. Slessor ,  Jan Liska ,  Petr Kapitola

IPC分类号： A01N43/20 ,  A01N25/08 ,  A01N27/00 ,  A01N31/02

CPC分类号： A01N43/20 ,  Y10S514/919

摘要： This invention relates to a composition and procedure for manipulating the behaviour of nun moth, Lymantria monacha (L.) and gypsy moth, Lymantria dispar (L.). More particularly, this invention relates to the preparation and use of chiral and racemic disparlure, chiral or racemic cis-7,8-epoxy-octadecane, 2-methyl-Z7-octadecene and Z7-octadene for manipulating the behaviour of nun moth and gypsy moth. A composition of chemicals for manipulating the behavior of nun moth and/or gypsy moth, said composition comprising two or more chemicals selected from the group consisting of: (a) 2-methyl-7R,8S-epoxy-octadecane (RS-disparlure); (b) 2-methyl-7S,8R-epoxy-octadecane (SR-disparlure); (c) 7R,8S-epoxy-octadecane; (d) 7S,8R-epoxy-octadecane; (e) 2-methyl-Z7-octadecene; and (f) Z7-octadecene.

摘要翻译： 本发明涉及一种操作尼姑蛾（Lymantria monacha L.）和吉卜斯蛾（Lymantria dispar）的行为的组合物和方法。 更具体地说，本发明涉及手性和外消旋脱除，手性或外消旋的顺式-7,8-环氧十八烷，2-甲基-Z7-十八碳烯和Z7-辛烯的制备和用途，用于操纵尼姑蛾和吉普赛人的行为 蛾。 一种用于操纵尼姑蛾和/或吉卜赛蛾行为的化学物质组合物，所述组合物包含两种或更多种选自以下的化学物质：（a）2-甲基-7R，8S-环氧十八烷（RS-分离） ; （b）2-甲基-7S，8R-环氧十八烷（SR-分离）; （c）7R，8S-环氧十八烷; （d）7S，8R-环氧 - 十八烷; （e）2-甲基-Z-十八碳烯; 和（f）Z7-十八碳烯。

公开(公告)号：US09199062B2

公开(公告)日：2015-12-01

申请号：US13256888

申请日：2010-03-10

申请人： Jan Liska ,  Madelene Eklund ,  Dan Karlsson ,  Jimmy Gidö Schon ,  Johan Rinman

发明人： Jan Liska ,  Madelene Eklund ,  Dan Karlsson ,  Jimmy Gidö Schon ,  Johan Rinman

IPC分类号： A61M25/00 ,  A61M25/06 ,  A61M25/02

CPC分类号： A61M25/0606 ,  A61M25/0097 ,  A61M25/02 ,  A61M25/0612 ,  A61M2025/0266

摘要： An inserter assembly for a peripheral catheter assembly configured with an adhesive plaster member, wherein the catheter tube extends through the plaster member. The inserter assembly includes a first inserter part having first and second legs, a bridge member connecting the first and second legs at a distance from each other, with the bridge member adapted for detachably engaging or holding at least a part of the needle module extending coaxially between the first and second legs. The inserter assembly includes a second inserter part for covering the needle. The plaster member impairs visual sight and the line of vision to the needle tip during puncture may be impaired. To prevent this the first inserter part serves for holding a back-folded part of the plaster member.

摘要翻译： 一种用于周边导管组件的插入器组件，其配置有胶粘剂构件，其中导管管延伸通过石膏构件。 插入器组件包括具有第一和第二腿部的第一插入器部件，将第一和第二腿部彼此间隔开地连接的桥接部件，桥接部件适于可拆卸地接合或保持同轴延伸的针模块的至少一部分 在第一和第二腿之间。 插入器组件包括用于覆盖针的第二插入器部分。 石膏构件损伤视力，穿刺期间针尖的视线可能受损。 为了防止这种情况，第一插入器部分用于保持石膏构件的折叠部分。

公开(公告)号：US20120010577A1

公开(公告)日：2012-01-12

申请号：US13256888

申请日：2010-03-10

申请人： Jan Liska ,  Madelene Eklund ,  Dan Karlsson ,  Jimmy Gidö Schön ,  Johan Rinman

发明人： Jan Liska ,  Madelene Eklund ,  Dan Karlsson ,  Jimmy Gidö Schön ,  Johan Rinman

IPC分类号： A61M5/32

CPC分类号： A61M25/0606 ,  A61M25/0097 ,  A61M25/02 ,  A61M25/0612 ,  A61M2025/0266

摘要： An inserter assembly for a peripheral catheter assembly configured with an adhesive plaster member, wherein the catheter tube extends through the plaster member. The inserter assembly includes a first inserter part having first and second legs, a bridge member connecting the first and second legs at a distance from each other, with the bridge member adapted for detachably engaging or holding at least a part of the needle module extending coaxially between the first and second legs. The inserter assembly includes a second inserter part for covering the needle. The plaster member impairs visual sight and the line of vision to the needle tip during puncture may be impaired. To prevent this the first inserter part serves for holding a back-folded part of the plaster member.

摘要翻译： 一种用于周边导管组件的插入器组件，其配置有胶粘剂构件，其中导管管延伸通过石膏构件。 插入器组件包括具有第一和第二腿部的第一插入器部件，将第一和第二腿部彼此间隔一定距离地连接的桥接部件，桥接部件适于可拆卸地接合或保持同轴延伸的针模块的至少一部分 在第一和第二腿之间。 插入器组件包括用于覆盖针的第二插入器部分。 石膏构件损伤视力，穿刺期间针尖的视线可能受损。 为了防止这种情况，第一插入器部分用于保持石膏构件的折叠部分。

公开(公告)号：US20100204565A1

公开(公告)日：2010-08-12

申请号：US12446098

申请日：2007-10-17

申请人： Henrik Falkén ,  Jan Liska

发明人： Henrik Falkén ,  Jan Liska

IPC分类号： A61M25/14 ,  A61B8/12 ,  A61B6/12 ,  B29C47/20

CPC分类号： A61B5/0215 ,  A61B5/14528 ,  A61B10/0045 ,  A61M25/0009

摘要： The invention relates to a microdialysis catheter comprising a multilumen tube (10) and a membrane (11), said tube exhibiting at least two longitudinally arranged inner channels (13,14), said channels extending from a proximal (20) end of the tube to the distal end (21) of the tube, whereat through-holes (12,15) are provided, one from each of said at least two channels to the outside of said tube, said channels (13,14) blocked for passage of liquid distally of the respective through-holes, a tubular membrane (11) arranged circumferentially around the tube (10) such as to cover the at least two through-holes (12,15), said membrane is sealingly fastened (22) to the tube thereby forming a dialysis chamber (18) between the tube and the membrane.

摘要翻译： 本发明涉及一种包含多腔管（10）和膜（11）的微透析导管，所述管呈现至少两个纵向布置的内通道（13,14），所述通道从管的近端（20）端延伸 到所述管的远端（21），其中设置通孔（12,15），一个从所述至少两个通道中的每一个通向所述管的外部，所述通道（13,14）被阻挡以通过 各个通孔的远端的液体，围绕管（10）周向布置的管状膜（11），以覆盖至少两个通孔（12,15），所述膜密封地紧固（22）到 从而在管和膜之间形成透析室（18）。

公开(公告)号：US09167997B2

公开(公告)日：2015-10-27

申请号：US13509939

申请日：2010-11-16

申请人： Anton Karlsson ,  Henrik Falkén ,  Gabriel Österdahl ,  Jan Liska

发明人： Anton Karlsson ,  Henrik Falkén ,  Gabriel Österdahl ,  Jan Liska

IPC分类号： A61B5/145 ,  A61B5/155 ,  A61B5/00

CPC分类号： A61B5/155 ,  A61B5/1427 ,  A61B5/14503 ,  A61B5/14528 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/15003 ,  A61B5/150274 ,  A61B5/15087 ,  A61B5/153 ,  A61B5/157 ,  A61B5/412 ,  A61B5/686 ,  A61B5/6876 ,  Y10T29/49826

摘要： The invention relates to a method and arrangement for continuously measuring substances in a pressurised body fluid. A probe (202) for enabling continuous measurement of the concentration of one or more substances in a pressurized body fluid is provided. The probe is adapted to be inserted into the pressurized body fluid, and comprises an interface and an outlet lumen. Furthermore, the probe is configured so that a continuous and spontaneous fluid flow is established from the body fluid through the interface to the outlet lumen. The fluid flow from the outlet may be analyzed by a sensor.

摘要翻译： 本发明涉及连续测量加压体液中的物质的方法和装置。 提供了用于能够连续测量加压体液中的一种或多种物质的浓度的探针（202）。 探针适于插入加压体液中，并且包括界面和出口腔。 此外，探针构造成使得从体液通过界面到出口腔建立连续和自发的流体流动。 来自出口的流体流可以由传感器分析。

公开(公告)号：US06811542B2

公开(公告)日：2004-11-02

申请号：US10177108

申请日：2002-06-24

申请人： Jan Liska ,  Anders Franco-Cereceda

发明人： Jan Liska ,  Anders Franco-Cereceda

IPC分类号： A61M100

CPC分类号： A61B5/145 ,  A61B5/14528

摘要： A microdialysis probe and catheter arrangement includes a catheter carrying in a distal end thereof a probe to be inserted in the body of a living being. The catheter has an elongate catheter body including a first channel for supplying a first fluid and a second channel for returning said first fluid. The first and second channels extend internally along the catheter body from a proximal end thereof to the probe. The probe includes a microdialysis membrane defining a dialysis chamber communicating with the first and second channels. A third channel extends internally along the catheter body and communicates with the second channel to supply a second fluid to thereto, thereby to increase the flow rate therein.

摘要翻译： 微透析探针和导管装置包括导管的远端，导管插入生物体内。 导管具有细长的导管主体，其包括用于供应第一流体的第一通道和用于返回所述第一流体的第二通道。 第一和第二通道沿着导管主体从其近端延伸到探针内部延伸。 探针包括限定与第一和第二通道连通的透析室的微透析膜。 第三通道沿着导管主体内部延伸并与第二通道连通以向其提供第二流体，从而增加其中的流速。

公开(公告)号：US06632315B2

公开(公告)日：2003-10-14

申请号：US09826956

申请日：2001-04-06

申请人： Jan Liska ,  Anders Franco-Cereceda

发明人： Jan Liska ,  Anders Franco-Cereceda

IPC分类号： B29C4700

CPC分类号： A61B5/145 ,  A61B5/14528 ,  B01D61/28 ,  Y10T156/1064

摘要： A method of manufacturing a microdialysis catheter, comprises the steps of extruding a flexible material to form an elongate catheter body having a substantially cylindrical outer surface and a plurality of continuous internal channels extending in the longitudinal direction of said catheter body; sealing a free end of said catheter body; providing in said surface at a distance from said free end an opening extending into said catheter body to communicate with a portion of a first of said channels; providing communication between said first channel and a second of said channels at a distance from said free end shorter that said distance; and covering said opening by a microdialysis membrane.

摘要翻译： 一种制造微透析导管的方法包括以下步骤：挤出柔性材料以形成具有基本上圆柱形的外表面和沿所述导管主体的纵向方向延伸的多个连续内部通道的细长导管主体; 密封所述导管体的自由端; 在所述表面上距所述自由端一定距离延伸到所述导管主体中以与所述第一通道的一部分连通的开口; 提供所述第一通道和所述通道之间的距离与所述距离相距一定距离的通信; 并用微透析膜覆盖所述开口

公开(公告)号：US08229546B2

公开(公告)日：2012-07-24

申请号：US12446098

申请日：2007-10-17

申请人： Henrik Falkén ,  Jan Liska

发明人： Henrik Falkén ,  Jan Liska

IPC分类号： A61M25/14 ,  A61B8/12 ,  A61B6/12 ,  B29C47/20

CPC分类号： A61B5/0215 ,  A61B5/14528 ,  A61B10/0045 ,  A61M25/0009

摘要： The invention relates to a microdialysis catheter comprising a multilumen tube (10) and a membrane (11), said tube exhibiting at least two longitudinally arranged inner channels (13,14), said channels extending from a proximal (20) end of the tube to the distal end (21) of the tube, whereat through-holes (12,15) are provided, one from each of said at least two channels to the outside of said tube, said channels (13,14) blocked for passage of liquid distally of the respective through-holes, a tubular membrane (11) arranged circumferentially around the tube (10) such as to cover the at least two through -holes (12,15), said membrane is sealingly fastened (22) to the tube thereby forming a dialysis chamber (18) between the tube and the membrane.

摘要翻译： 本发明涉及一种包含多腔管（10）和膜（11）的微透析导管，所述管呈现至少两个纵向布置的内通道（13,14），所述通道从管的近端（20）端延伸 到所述管的远端（21），其中设置通孔（12,15），一个从所述至少两个通道中的每一个通向所述管的外部，所述通道（13,14）被阻挡以通过 各个通孔的远端的液体;围绕管（10）周向布置的管状膜（11），以覆盖至少两个通孔（12,15），所述膜密封地紧固（22）到 从而在管和膜之间形成透析室（18）。

公开(公告)号：US07083598B2

公开(公告)日：2006-08-01

申请号：US10228223

申请日：2002-08-27

申请人： Jan Liska

发明人： Jan Liska

IPC分类号： A61M5/32

CPC分类号： A61M25/00 ,  A61M25/0097 ,  A61M25/02 ,  Y10S128/26

摘要： A transcutan catheter assembly including a catheter having a distal end and a proximal end, and a collar of a relatively flexible material having an upper surface and a lower surface. The catheter extends in a fluid tight manner through the collar such that the distal end of the catheter protrudes underneath the lower surface of the collar and its proximal end is accessible at the upper surface for the connection of tubing to the catheter. The lower surface of the collar has adhesive properties for fluid tight attachment to the skin of a patient.

摘要翻译： 包括具有远端和近端的导管的经颅导管组件和具有上表面和下表面的相对柔性材料的套环。 导管以流体密封的方式延伸通过套环，使得导管的远端突出在套环的下表面下方，并且其近端可在上表面处接近以将管连接到导管。 套环的下表面具有用于与患者的皮肤流体紧密连接的粘合性质。

公开(公告)号：US06346090B1

公开(公告)日：2002-02-12

申请号：US09359312

申请日：1999-07-23

申请人： Jan Liska ,  Anders Franco-Cereceda

发明人： Jan Liska ,  Anders Franco-Cereceda

IPC分类号： A61M100

CPC分类号： A61B5/145 ,  A61B5/14528 ,  A61M25/00

摘要： A catheter for insertion into a blood vessel of a living being, which includes an elongated catheter body and membrane defining a dialysis chamber; a first channel provided for delivery of dialysis liquid to the dialysis chamber and a second channel provided for the discharge of dialysis liquid from the dialysis chamber, wherein the dialysis chamber comprises a plurality of tubular members, each having an inlet end and an outlet end, all the inlet ends being connected to the first channel and all the outlet ends being connected to the second channel.

摘要翻译： 用于插入活体血管的导管，其包括限定透析室的细长导管体和膜; 提供用于将透析液体输送到透析室的第一通道和用于从透析室排出透析液体的第二通道，其中透析室包括多个管状构件，每个管状构件具有入口端和出口端， 所有入口端连接到第一通道，并且所有出口端连接到第二通道。