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    Synergistic mixtures of C6- to C12-alkanediols and tropolone (derivatives)
    4.
    发明授权
    Synergistic mixtures of C6- to C12-alkanediols and tropolone (derivatives) 有权
    C6-至C12-烷二醇与托普龙酮（衍生物）的协同混合物

    公开(公告)号：US08647651B2

    公开(公告)日：2014-02-11

    申请号：US11460587

    申请日：2006-07-27

    申请人： Gerhard Schmaus ,  Sabine Lange ,  Ravikumar Pillai ,  William Johncock

    发明人： Gerhard Schmaus ,  Sabine Lange ,  Ravikumar Pillai ,  William Johncock

    IPC分类号： A01N31/02 ,  A01N35/06

    CPC分类号： A01N35/06 ,  A01N31/02 ,  A01N2300/00

    摘要： Antimicrobial mixtures comprising or consisting of: one or more branched or unbranched alkanediols having 6-12 carbon atoms, one, two or more compounds chosen from the group consisting of the tropolones of the formula (I) wherein the substituents R1, R2, R3, R4 and R5 independently of one another have the following meaning: H; linear or branched, saturated or unsaturated, aliphatic hydrocarbon radical having up to 30 C atoms; OH; OR6, wherein R6 is a linear or branched, saturated or unsaturated, aliphatic hydrocarbon radical having up to 30 C atoms; COOH; COOR7, wherein R7 is a linear or branched, saturated or unsaturated, aliphatic hydrocarbon radical having up to 30 C atoms; NO2; NH2; F, Cl, Br, I; are described.

    摘要翻译： 包含或由以下组成的抗微生物混合物：一种或多种具有6-12个碳原子的支链或非支链烷二醇，一种，两种或更多种选自式（I）的托乐酮的化合物，其中取代基R 1，R 2，R 3， R 4和R 5彼此独立地具有以下含义：H; 具有至多30个C原子的直链或支链，饱和或不饱和的脂族烃基; 哦; OR 6，其中R 6是具有至多30个C原子的直链或支链饱和或不饱和的脂族烃基; COOH; COOR 7，其中R 7是具有至多30个C原子的直链或支链饱和或不饱和的脂族烃基; NO2; NH2; F，Cl，Br，I; 被描述。

    STABILIZED PREPARATIONS COMPRISING PHENOLIC COMPOUNDS AND BENZOPHENONES
    6.
    发明申请
    STABILIZED PREPARATIONS COMPRISING PHENOLIC COMPOUNDS AND BENZOPHENONES 审中-公开
    包含苯酚化合物和苯并噻唑的稳定化制剂

    公开(公告)号：US20090130035A1

    公开(公告)日：2009-05-21

    申请号：US12159866

    申请日：2007-01-05

    申请人： Sabine Lange ,  Gerhard Schmaus ,  Gabriele Vielhaber ,  Karin Schaper

    发明人： Sabine Lange ,  Gerhard Schmaus ,  Gabriele Vielhaber ,  Karin Schaper

    IPC分类号： A61K8/35 ,  A61K31/12 ,  C07C49/215

    CPC分类号： A61K8/347 ,  A61K8/35 ,  A61K2800/52 ,  A61K2800/782 ,  A61Q5/08 ,  A61Q17/04 ,  A61Q19/02 ,  A61Q19/08

    摘要： The present invention relates primarily to a cosmetic and/or pharmaceutical preparation comprising of consisting of one or more phenolic compounds of the formula (I) where for formula (I) it is the case that: R1, R2, R3, R4 and R5 are independently of one another hydrogen, halogen, an OH group, methyl or a linear or branched alkyl having 2, 3, 4 or 5 C atoms, with 1, 2 or 3 different radicals from the group R1, R2, R3, R4 and R5 simultaneously representing an OH group, R6 and R7 are independently of one another hydrogen, methyl or a linear or branched alkyl having 2, 3, 4 or 5 C atoms, n is an integer from 0 to 20 and R8 is methyl or a linear or branched alkyl having 2 or 3 C atoms, a cycloalkyl having 3, 4, 5, 6 or 7 C atoms or a phenyl and one or more compounds of the formula (II) where for formula (II) it is the case that: R9, R10, R11 and R12 independently of one another are hydrogen, methyl, an OH group or a group —O—R13 and R13 is methyl or a linear or branched alkyl having 2, 3, 4, 5, 6, 7, 8, 9 or 10 C atoms, and to uses of compounds of the formula (II) for stabilizing compounds of the formula (I), and also to methods of stabilizing compounds of the formula (I).

    摘要翻译： 本发明主要涉及包含一种或多种式（I）的酚类化合物的化妆品和/或药物制剂，其中对于式（I），其中R1，R2，R3，R4和R5是 独立于氢，卤素，OH基，甲基或具有2,3,4或5个C原子的直链或支链烷基，与R1，R2，R3，R4和R5中的1,2或3个不同的基团 同时表示OH基团，R6和R7彼此独立地为氢，甲基或具有2,3,4或5个C原子的直链或支链烷基，n为0至20的整数，R8为甲基或直链或支链烷基， 具有2或3个C原子的支链烷基，具有3,4,5,6或7个C原子的环烷基，或苯基和一种或多种式（II）化合物，其中式（II）的情况是：R9 R 10，R 11和R 12彼此独立地是氢，甲基，OH基或-O-R 13基，R 13是甲基或具有2,3， 4，5，6，7，8，9或10个C原子，以及式（II）化合物用于稳定式（I）化合物的用途，以及稳定式（I）化合物的方法， 。

    SYNERGISTIC MIXTURES OF C6- TO C12-ALKANEDIOLS AND TROPOLONE (DERIVATIVES)
    7.
    发明申请
    SYNERGISTIC MIXTURES OF C6- TO C12-ALKANEDIOLS AND TROPOLONE (DERIVATIVES) 有权
    C6-对C12-烷烃和三聚氰胺（衍生物）的协同混合物

    公开(公告)号：US20070059331A1

    公开(公告)日：2007-03-15

    申请号：US11460587

    申请日：2006-07-27

    申请人： Gerhard Schmaus ,  Sabine Lange ,  Ravikumar Pillai ,  William Johncock

    发明人： Gerhard Schmaus ,  Sabine Lange ,  Ravikumar Pillai ,  William Johncock

    IPC分类号： A01N35/00 ,  A01N31/00

    CPC分类号： A01N35/06 ,  A01N31/02 ,  A01N2300/00

    摘要： Antimicrobial mixtures comprising or consisting of: one or more branched or unbranched alkanediols having 6-12 carbon atoms, one, two or more compounds chosen from the group consisting of the tropolones of the formula (I) wherein the substituents R1, R2, R3, R4 and R5 independently of one another have the following meaning: H; linear or branched, saturated or unsaturated, aliphatic hydrocarbon radical having up to 30 C atoms; OH; OR6, wherein R6 is a linear or branched, saturated or unsaturated, aliphatic hydrocarbon radical having up to 30 C atoms; COOH; COOR7, wherein R7 is a linear or branched, saturated or unsaturated, aliphatic hydrocarbon radical having up to 30 C atoms; NO2; NH2; F, Cl, Br, I; are described.

    摘要翻译： 包含或由以下组成的抗微生物混合物：一种或多种具有6-12个碳原子的支链或非支链烷二醇，一种，两种或更多种选自式（I）的托乐酮的化合物，其中取代基R 1，R 2，R 3， R 4和R 5彼此独立地具有以下含义：H; 具有至多30个C原子的直链或支链，饱和或不饱和的脂族烃基; 哦; OR 6，其中R 6是具有至多30个C原子的直链或支链饱和或不饱和的脂族烃基; COOH; COOR 7，其中R 7是具有至多30个C原子的直链或支链饱和或不饱和的脂族烃基; NO 2 NH 2; F，Cl，Br，I; 被描述。

    SYNERGISTIC ACTIVE PREPARATIONS COMPRISING DIPHENYLMETHANE DERIVATIVES AND FURTHER SKIN AND/OR HAIR LIGHTENING AND/OR SENILE KERATOSIS REDUCING COMPOUNDS
    8.
    发明申请
    SYNERGISTIC ACTIVE PREPARATIONS COMPRISING DIPHENYLMETHANE DERIVATIVES AND FURTHER SKIN AND/OR HAIR LIGHTENING AND/OR SENILE KERATOSIS REDUCING COMPOUNDS 审中-公开
    包含二苯基甲基衍生物的协同活性制剂和进一步的皮肤和/或头发亮度和/或高效减毒化合物

    公开(公告)号：US20090148391A1

    公开(公告)日：2009-06-11

    申请号：US12159951

    申请日：2007-01-05

    申请人： Gerhard Schmaus ,  Sabine Lange ,  Gabriele Vielhaber ,  Karin Schaper ,  Ravikumar Pillai

    发明人： Gerhard Schmaus ,  Sabine Lange ,  Gabriele Vielhaber ,  Karin Schaper ,  Ravikumar Pillai

    IPC分类号： A61K8/97 ,  A61K31/05 ,  A61Q17/04 ,  A61K36/48

    CPC分类号： A61K8/347 ,  A61K8/35 ,  A61K2800/52 ,  A61K2800/782 ,  A61Q5/08 ,  A61Q17/04 ,  A61Q19/02 ,  A61Q19/08

    摘要： The present invention relates to specific synergistic active skin- and/or hair-lightening and/or senile keratosis-reducing (cosmetic or pharmaceutical) preparations comprising a mixture comprising or consisting of a) a tyrosinase-inhibiting amount of one or more compounds of the formula 1:  wherein: R1 is hydrogen, methyl, straight-chain or branched alkyl having 2-4 C atoms, OH or halogen, R2 is hydrogen, methyl or straight-chain or branched alkyl having 2-5 C atoms, R3 is methyl or straight-chain or branched alkyl having 2-5 C atoms, and R4 and R5 are, independently of one another hydrogen, methyl, straight-chain or branched alkyl having 2-5 C atoms, OH or halogen and b) a skin- and/or hair lightening and/or senile keratosis-reducing amount of one or more compounds selected from the group consisting of (i) chelating agents, (ii) phenolic derivatives, plant extracts with an amount of phenolic derivatives and (iii) organic acid derivatives as well as uses thereof.

    摘要翻译： 本发明涉及具体的协同增效活性皮肤和/或发发轻度和/或老年角化病减少剂（化妆品或药物）制剂，其包含混合物，其包含或由以下组成：a）酪氨酸酶抑制量的一种或多种化合物 式1：其中：R1是氢，甲基，具有2-4个C原子的直链或支链烷基，OH或卤素，R2是氢，甲基或具有2-5个C原子的直链或支链烷基，R3是甲基 或具有2-5个C原子的直链或支链烷基，R 4和R 5彼此独立地为具有2-5个C原子的氢，甲基，直链或支链烷基，OH或卤素，和b） 和/或毛发发光和/或老年性角化病减少量的一种或多种选自（i）螯合剂，（ii）酚衍生物，具有一定量酚衍生物的植物提取物和（iii）有机酸 衍生物及其用途。

    USE OF 1,2-DECANEDIOL FOR SEBUM REDUCTION AND COSMETIC AND/OR DERMATOLOGICAL FORMULATIONS COMPRISING 1,2-DECANEDIOL
    9.
    发明申请
    USE OF 1,2-DECANEDIOL FOR SEBUM REDUCTION AND COSMETIC AND/OR DERMATOLOGICAL FORMULATIONS COMPRISING 1,2-DECANEDIOL 审中-公开
    使用1,2-癸醇用于减少和减少包含1,2-癸醇的化妆和/或皮肤配方

    公开(公告)号：US20100324152A1

    公开(公告)日：2010-12-23

    申请号：US12446190

    申请日：2007-10-12

    申请人： Gerhard Schmaus ,  Sabine Lange ,  Joachim Roding

    发明人： Gerhard Schmaus ,  Sabine Lange ,  Joachim Roding

    IPC分类号： A61K31/045 ,  C07C31/18

    CPC分类号： A61K8/345 ,  A61Q19/008 ,  A61Q19/10

    摘要： The present invention relates to a use of 1,2-decanediol for reduction of the sebum concentration of the skin, a cosmetic and/or dermatological formulation for topical application comprising 1,2-decanediol, a method for reduction of the sebum concentration of the skin and a use of 1,2-decanediol and a method for assisting the penetration of one, two, three, four or more active compounds into areas of the skin with increased sebum production.

    摘要翻译： 本发明涉及1,2-癸二醇用于降低皮肤的皮脂浓度，用于局部施用的化妆品和/或皮肤病学制剂，包括1,2-癸二醇，降低皮脂含量的方法 皮肤和1,2-癸二醇的使用以及一种辅助将一种，两种，三种，四种或更多种活性化合物渗入皮肤区域并增加皮脂产生的方法。

    MIXTURES WITH A COLLAGEN SYNTHESIS BOOSTING ACTION
    10.
    发明申请
    MIXTURES WITH A COLLAGEN SYNTHESIS BOOSTING ACTION 审中-公开
    混合物与胶原蛋白合成促进作用

    公开(公告)号：US20090232915A1

    公开(公告)日：2009-09-17

    申请号：US12401390

    申请日：2009-03-10

    申请人： Gerhard Schmaus ,  Helge Franke ,  Sabine Lange

    发明人： Gerhard Schmaus ,  Helge Franke ,  Sabine Lange

    IPC分类号： A61K8/97 ,  A61Q19/08

    CPC分类号： A61K8/676 ,  A61K8/97 ,  A61K2800/70 ,  A61Q19/08

    摘要： The invention relates to synergistically active, ternary mixtures which boost collagen synthesis and to the uses thereof, in particular for slowing down skin ageing and for wound healing of damaged skin. The invention furthermore relates to the use of the ternary mixtures according to the invention for treating the oral cavity and pharynx, and in particular therein for preventing and slowing down periodontitis, for building up periodontal connective tissue and for preventing and treating infections in the oral cavity and for wound healing in the oral cavity.

    摘要翻译： 本发明涉及促进胶原合成及其用途的协同活性三元混合物，特别是用于减缓皮肤老化和损伤皮肤的伤口愈合。 本发明还涉及根据本发明的三元混合物用于治疗口腔和咽部，特别是其中用于预防和减缓牙周炎，用于建立牙周结缔组织和用于预防和治疗口腔感染的用途 并且用于口腔中的伤口愈合。