公开(公告)号：US20050140837A1

公开(公告)日：2005-06-30

申请号：US10748562

申请日：2003-12-30

申请人： Gregory Crawford ,  James Eakin ,  Marc Radcliffe

发明人： Gregory Crawford ,  James Eakin ,  Marc Radcliffe

IPC分类号： G02F1/1337 ,  G02F1/136

CPC分类号： G02F1/133788

摘要： A method includes exposing an alignment material to an interference pattern to cause a chemical reaction in the alignment material and exposing the alignment material to a liquid crystal, where the liquid crystal aligns relative to the alignment material based on the interference pattern.

摘要翻译： 一种方法包括将对准材料暴露于干涉图案以引起对准材料中的化学反应并将对准材料暴露于液晶，其中液晶基于干涉图案相对于取向材料取向。

公开(公告)号：US20100021400A1

公开(公告)日：2010-01-28

申请号：US12430739

申请日：2009-04-27

申请人： Gregory D. Jay ,  Gregory Crawford

发明人： Gregory D. Jay ,  Gregory Crawford

IPC分类号： A61K8/18 ,  A61Q17/04

CPC分类号： A61K8/466 ,  A61K8/0295 ,  A61K2800/434 ,  A61K2800/81 ,  A61Q17/04 ,  A61Q19/004

摘要： The invention relates to topical compositions comprising a fluorescent dye that absorbs UVA and UVB radiation and converts it into a healing light, in combination with a dermatologically acceptable excipient. The compositions of the invention are useful for repairing photo-damaged skin cells and reducing or preventing future skin damage as a result of exposure to UV light.

摘要翻译： 本发明涉及包含与皮肤病学可接受的赋形剂组合的吸收UVA和UVB辐射并将其转化为愈合光的荧光染料的局部组合物。 本发明的组合物可用于修复受光损伤的皮肤细胞，并且由于暴露于UV光而减少或防止将来的皮肤损伤。

公开(公告)号：US20060105357A1

公开(公告)日：2006-05-18

申请号：US11051736

申请日：2005-02-04

申请人： Frank Benesch ,  Victoria Barbata ,  Robert Valentini ,  Herman Vandenburgh ,  Gregory Crawford

发明人： Frank Benesch ,  Victoria Barbata ,  Robert Valentini ,  Herman Vandenburgh ,  Gregory Crawford

IPC分类号： C12Q1/68 ,  G01N1/30 ,  C12M1/34

CPC分类号： B01L3/5088 ,  B01L3/5085 ,  B01L2300/0636 ,  B01L2300/0819 ,  G01N33/5088 ,  G01N33/6887

摘要： Described are assemblies for screening a compound for bioactivity, the assemblies comprising a tissue and a sensor. A change in a biological parameter is measured by the sensor, such that a change in a parameter occurring when the tissue is contacted with a candidate compound is detected by the sensor. Assemblies provided herein include single sensor/tissue assemblies and arrays of such assemblies, including plates comprising tissues in combination with one or more sensors. Also provided are methods of screening a compound using tissue/sensor tissue assemblies as described.

摘要翻译： 描述了用于筛选用于生物活性的化合物的组件，所述组件包括组织和传感器。 通过传感器测量生物参数的变化，使得当传感器检测到组织与候选化合物接触时发生的参数变化。 本文提供的组件包括单个传感器/组织组件和这种组件的阵列，包括与一个或多个传感器组合的组织的板。 还提供了使用如所述的组织/传感器组织组件筛选化合物的方法。

公开(公告)号：US20070123762A1

公开(公告)日：2007-05-31

申请号：US10587777

申请日：2005-01-28

申请人： Gregory Crawford ,  Gregory Jay

发明人： Gregory Crawford ,  Gregory Jay

IPC分类号： A61B5/00 ,  G01N33/48

CPC分类号： G01J3/12 ,  A61B5/14546 ,  A61B5/1455 ,  G01J3/32 ,  G01J3/36 ,  G01J3/51 ,  G01J2003/1213 ,  G01N21/255 ,  G01N2201/067

摘要： In the spectrometric device of this invention the objective lens and diffraction grating are replaced with a spectral imaging apparatus on electrically switchable color filter technology. The spectrometric device includes wavelength filter means as the spectral imaging apparatus for transmitting or reflecting wavelengths of light, light intensity sensor means arranged and disposed to measure the intensity of the wavelengths transmitted or reflected by the wavelength filter means and generate an electrical signal from the wavelengths transmitted or reflected, output processing means connected to the light intensity sensor means to receive and process the output from the light intensity sensor means, and display means connected to the output processing means to display the output.

摘要翻译： 在本发明的光谱测量装置中，物镜和衍射光栅由可电切换滤色器技术的光谱成像装置代替。 光谱测量装置包括作为用于发射或反射波长的光谱成像装置的波长滤波器装置，布置和设置的光强度传感器装置，以测量由波长滤波器装置传输或反射的波长的强度，并从波长产生电信号 发送或反射的输出处理装置，连接到光强度传感器装置以接收和处理来自光强度传感器装置的输出;以及显示装置，连接到输出处理装置以显示输出。

公开(公告)号：US20050087021A1

公开(公告)日：2005-04-28

申请号：US10764263

申请日：2004-01-23

申请人： Gregory Crawford ,  Darran Cairns ,  Christopher Bowley ,  Sorasak Danworaphong ,  Adam Fontecchio ,  Sadeg Faris ,  Le Li

发明人： Gregory Crawford ,  Darran Cairns ,  Christopher Bowley ,  Sorasak Danworaphong ,  Adam Fontecchio ,  Sadeg Faris ,  Le Li

IPC分类号： G01B11/16 ,  G01L1/24 ,  G02F1/1334

CPC分类号： G01B11/165 ,  G01B11/18 ,  G01L1/241 ,  G02F1/13342

摘要： A reflective strain gauge includes an holographically-formed polymer dispersed liquid crystal (H-PDLC) film comprising layers of liquid crystal (LC) droplets in a matrix polymer, the H-PDLC film having a reflection or transmission grating capable of reflecting or transmitting light of a selected wavelength, and means for adhering the film to a surface of a workpiece for monitoring the strain at said surface. A change in the nature of the reflected light is an indication of strain. Also included is a polarizing material having an holographically-formed polymer dispersed liquid crystal (H-PDLC) film comprising layers of liquid crystal (LC) droplets in a matrix polymer, the H-PDLC film having a reflection grating capable of reflecting light of a selected wavelength, wherein the reflection grating of the H-PDLC film is oriented, such that the refractive index parallel to said axis of orientation (ne) is greater than the refractive index perpendicular to said axis (no).

摘要翻译： 反射应变计包括在基质聚合物中包含液晶（LC）液滴层的全息形成的聚合物分散液晶（H-PDLC）膜，该H-PDLC膜具有能够反射或透射光的反射或透射光栅 以及用于将膜粘附到工件的表面以用于监测所述表面处的应变的装置。 反射光的性质的变化表明了应变。 还包括具有在基体聚合物中包含液晶（LC）液滴层的全息形成的聚合物分散液晶（H-PDLC）膜的偏振材料，该H-PDLC膜具有能够反射光的反射光栅 选择的波长，其中所述H-PDLC膜的反射光栅被取向，使得平行于所述取向轴（n）的折射率大于垂直于所述轴线的折射率（n ）。